Displaying drugs 426 - 450 of 12359 in total
Fenfluramine
Dravet syndrome is a pediatric encephalopathy that typically manifests within the first year of life following exposure to elevated temperatures. It is characterized by recurrent pharmacoresistant seizures, which increase in frequency and severity with disease progression. Concomitantly with these seizures, patients typically display delayed development and neurocognitive impairment.[A214694, A214709, A214712,...
Approved
Illicit
Investigational
Withdrawn
Matched Synonyms: … 1-(m-trifluoromethyl-phenyl)-2-ethylaminopropane …
Matched Iupac: … ethyl({1-[3-(trifluoromethyl)phenyl]propan-2-yl})amine …
Matched Description: … Dravet syndrome is a pediatric encephalopathy that typically manifests within the first year of life ... [A214694, A214709, A214712, A214715] Fenfluramine is a serotonergic phenethylamine originally used as ... A214700] Fenfluramine was granted initial FDA approval in 1973 prior to its withdrawal; it was granted a …
Matched Iupac: … ethyl({1-[3-(trifluoromethyl)phenyl]propan-2-yl})amine …
Matched Description: … Dravet syndrome is a pediatric encephalopathy that typically manifests within the first year of life ... [A214694, A214709, A214712, A214715] Fenfluramine is a serotonergic phenethylamine originally used as ... A214700] Fenfluramine was granted initial FDA approval in 1973 prior to its withdrawal; it was granted a …
Coral snake (micrurus fulvius) immune globulin antivenin (equine)
North American Coral Snake Antivenin (Equine) is a horse-derived antivenin indicated for the treatment of envenomation caused by North American coral snake bites. It is intravenously administered so that the antivenin binds to and neutralizes coral snake venom.
The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins...
Approved
Experimental
Matched Description: … North American Coral Snake Antivenin (Equine) is a horse-derived antivenin indicated for the treatment ... The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins obtained by …
Epoprostenol
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Iupac: … 5-[(2Z,3aR,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2- …
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. …
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. …
Interferon alfa-2a
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched International brands: … Roferon A …
Matched Description: … Interferon a (human leukocyte protein moiety reduced). ... A type I interferon consisting of 165 amino acid residues with lysine in position 23. …
Matched Products: … Roferon-A Solution 3 Million I.U./ml ... ROFERON-A PREFILLED SYRINGE FOR INJECTION 3 miu/0.5 ml ... ROFERON - A ROCHE SOLUCION INYECTABLE 3 K/U.I. …
Matched Description: … Interferon a (human leukocyte protein moiety reduced). ... A type I interferon consisting of 165 amino acid residues with lysine in position 23. …
Matched Products: … Roferon-A Solution 3 Million I.U./ml ... ROFERON-A PREFILLED SYRINGE FOR INJECTION 3 miu/0.5 ml ... ROFERON - A ROCHE SOLUCION INYECTABLE 3 K/U.I. …
Ferrous cysteine glycinate
Approved
Matched Synonyms: … Ferrous cysteine glycinate chelate (1:2:1) …
Matched Iupac: … lambda2-iron(2+) (2R)-2-amino-3-sulfanylpropanoic acid 2-aminoacetic acid (2R)-2-amino-3-sulfanidylpropanoate …
Matched Iupac: … lambda2-iron(2+) (2R)-2-amino-3-sulfanylpropanoic acid 2-aminoacetic acid (2R)-2-amino-3-sulfanidylpropanoate …
Tenofovir alafenamide
Tenofovir alafenamide is a novel tenofovir prodrug developed in order to improve renal safety when compared to the counterpart tenofovir disoproxil. Both of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a novel oxycarbonyloxymethyl linkers to improve the oral bioavailability and intestinal...
Approved
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl] …
Matched Description: … Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when ... of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a ... [A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Tenofovir alafenamide is a novel [tenofovir] prodrug developed in order to improve renal safety when ... of these prodrugs were first created to cover the polar phosphonic acid group on tenofovir by using a ... [A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Diloxanide furoate
Approved
Matched Synonyms: … 2,2-dichloroacetamido-4-n-methylphenyl 2-furoate ... 4-(n-methyl-2,2-dichloroacetamido)phenyl 2-furoate …
Matched Iupac: … 4-(2,2-dichloro-N-methylacetamido)phenyl furan-2-carboxylate …
Matched Iupac: … 4-(2,2-dichloro-N-methylacetamido)phenyl furan-2-carboxylate …
Tinidazole
A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Approved
Investigational
Matched Synonyms: … 1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole …
Matched Description: … A nitroimidazole antitrichomonal agent effective against _Trichomonas vaginalis_, _Entamoeba histolytica …
Matched Mixtures name: … TRİVAG 300 MG / 200 MG/ 100 MG OVÜL, 3 ADET ... GYNOMAX XL 200 MG/ 300 MG/100 MG VAJINAL OVÜL, 3 ADET …
Matched Iupac: … 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole …
Matched Description: … A nitroimidazole antitrichomonal agent effective against _Trichomonas vaginalis_, _Entamoeba histolytica …
Matched Mixtures name: … TRİVAG 300 MG / 200 MG/ 100 MG OVÜL, 3 ADET ... GYNOMAX XL 200 MG/ 300 MG/100 MG VAJINAL OVÜL, 3 ADET …
Black widow spider antivenin (equine)
Black widow spider (Latrodectus mactans) antivenin is a treatment for black widow spider bites derived from the serum of healthy horses immunized against black widow spider venom.
Approved
Matched Synonyms: … LATRODECTUS IMMUNE F(AB)2 …
Matched Description: … Black widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived …
Matched Description: … Black widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived …
Triclabendazole
Triclabendazole, manufactured by Novartis pharmaceuticals, is an antihelminthic drug that was approved by the FDA in February 2019 for the treatment of fascioliasis in humans.[FDA label, L5452] Fascioliasis is a parasitic infection often caused by the helminth, Fasciola hepatica, which is also known as “the common liver fluke” or “the...
Approved
Investigational
Matched Iupac: … 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-1,3-benzodiazole …
Matched Description: … [FDA label, L5452] Fascioliasis is a parasitic infection often caused by the helminth, _Fasciola hepatica …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … [FDA label, L5452] Fascioliasis is a parasitic infection often caused by the helminth, _Fasciola hepatica …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Carya tomentosa pollen
Carya tomentosa pollen is the pollen of the Carya tomentosa plant. Carya tomentosa pollen is mainly used in allergenic testing.
Approved
Influenza B virus B/Hubei-Wujiagang/158/2009 BX-39 hemagglutinin antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Calcium undecylenate
Approved
Experimental
Voretigene neparvovec
Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy. An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. This type of virus is vastly used as vectors for gene therapy because they can...
Approved
Matched Description: … It is not pathogenic and it causes a very mild immune response. ... [L1094] An adeno-associated virus is a small virus that infects humans and other primates. ... of this adeno-associated virus is the high predictability, unlike retrovirus, as they associate with a …
Etrasimod
Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that targets the S1P1,4,5 with no detectable activity on S1P2 and S1P3 receptors. S1P receptors are membrane-derived lysophospholipid signaling molecules that are involved in the sequestration of circulating peripheral lymphocytes in lymph nodes. Therefore, S1P receptor modulators like etrasimod...
Approved
Matched Iupac: … 2-[(3R)-7-{[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy}-1H,2H,3H,4H-cyclopenta[b]indol-3-yl]acetic …
Matched Description: … targets the S1P1,4,5 with no detectable activity on S1P2 and S1P3 receptors ... 2-mg daily dose regimen of etrasimod, with a 32% and 26% remission rate observed in UC 52 and UC 12 trials ... Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … targets the S1P1,4,5 with no detectable activity on S1P2 and S1P3 receptors ... 2-mg daily dose regimen of etrasimod, with a 32% and 26% remission rate observed in UC 52 and UC 12 trials ... Etrasimod is a synthetic next-generation selective Sphingosine 1-phosphate (S1P) receptor modulator that …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ciltacabtagene autoleucel
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Description: … [L40739] Patient T-cells are reprogrammed with a transgene encoding a specific chimeric antigen receptor ... Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. ... [L40749] There have been a number of treatments developed for multiple myeloma (e.g. …
Halothane
A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Approved
Vet approved
Matched Synonyms: … 1,1,1-trifluoro-2-bromo-2-chloroethane ... 1,1,1-trifluoro-2-chloro-2-bromoethane ... 2-bromo-2-chloro-1,1,1-trifluoroethane …
Matched Iupac: … 2-bromo-2-chloro-1,1,1-trifluoroethane …
Matched Description: … A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little …
Matched Iupac: … 2-bromo-2-chloro-1,1,1-trifluoroethane …
Matched Description: … A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little …
Conivaptan
Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Approved
Investigational
Matched Synonyms: … 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide …
Matched Iupac: … )-[1,1'-biphenyl]-2-carboxamide ... N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),2(6),3,10,12-pentaene-9-carbonyl}phenyl …
Matched Description: … Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … )-[1,1'-biphenyl]-2-carboxamide ... N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),2(6),3,10,12-pentaene-9-carbonyl}phenyl …
Matched Description: … Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Bromotheophylline
Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive...
Approved
Matched Description: … Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline ... [A33018] Bromotheophylline is categorized on the FDA as a drug substance with an inactive state since ... From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics …
Matched Salts cas: … 606-04-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 606-04-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Interferon alfa-2b
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … Intron A ... Intron A (Interferon α2b) …
Matched Description: … A type I interferon consisting of 165 amino acid residues with arginine in position 23. …
Matched Mixtures name: … Intron A ... Intron A ... Intron A - Kit (pws+diluent) 3000000iu/vial …
Matched Products: … INTRON A SOLUCION INYECTABLE (H.S.A. FREE) 3 MU.I ... Intron A ... Intron A - Liq 5000000iu/ml …
Matched Description: … A type I interferon consisting of 165 amino acid residues with arginine in position 23. …
Matched Mixtures name: … Intron A ... Intron A ... Intron A - Kit (pws+diluent) 3000000iu/vial …
Matched Products: … INTRON A SOLUCION INYECTABLE (H.S.A. FREE) 3 MU.I ... Intron A ... Intron A - Liq 5000000iu/ml …
Vonicog alfa
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Description: … Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. …
Benzoin
Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide, and is used in organic syntheses. This should not be confused with benzoin gum from STYRAX (see DB11222). Benzoin is an FDA-approved colour additive used for marking fruits and vegetables.
Approved
Experimental
Matched Synonyms: … 2-Hydroxy-1,2-diphenylethanone ... Hydroxy-2-phenyl acetophenone …
Matched Iupac: … 2-hydroxy-1,2-diphenylethan-1-one …
Matched Description: … Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide …
Matched Iupac: … 2-hydroxy-1,2-diphenylethan-1-one …
Matched Description: … Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide …
Benzocaine
Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Mixtures name: … E-Vac Plus ... NORAVER C ... Adventure Medical Kits 1-2 Person First Aid …
Matched Products: … Mark 3 ... KANK-A ... NeuroMed FA …
Matched Products: … Mark 3 ... KANK-A ... NeuroMed FA …
Displaying drugs 426 - 450 of 12359 in total