Displaying drugs 451 - 475 of 11573 in total
Lesinurad
Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Description: … In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... Marketed as the product Zurampic, it is indicated for use in combination with a xanthine oxidase inhibitor ... hyperuricemia associated with gout in
patients who have not achieved target serum uric acid levels with a …
Urea C-14
Urea 14C is a urea molecule radiolabelled with a radioactive carbon-14. It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed as PyTest) for the detection of Helicobacter pylori infections. H pylori is a common stomach bacteria that has been linked...
Approved
Matched Description: … Urea 14C is a urea molecule radiolabelled with a radioactive carbon-14. ... H pylori is a common stomach bacteria that has been linked to a variety of upper gastrointestinal disorders ... It is currently used for the Urea Breath Test (UBT) and is available as a rapid diagnostic test (marketed …
Nafcillin
A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Description: … A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic ... It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections ... It may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360 …
Salmeterol
Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Description: … Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for ... [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 …
Phenoxyethanol
Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial...
Approved
Matched Description: … Phenoxyethanol is a colorless liquid with a pleasant odor. ... It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, ... Phenoxyethanol is a colorless, clear, oily liquid with a faint aromatic odor at room temperature and …
Trypan blue free acid
Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Description: … of a mature cataract. ... Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sodium zirconium cyclosilicate
Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … powder for oral suspension that acts as a highly selective potassium removing agent. ... Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Anethole
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sulfathiazole
Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide.
Except for those formulated for vaginal use, the FDA withdrew its approval for the use of...
Approved
Vet approved
Withdrawn
Matched Description: … Sulfathiazole is a short-acting sulfa drug. ... It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. …
Norepinephrine
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … It is also found in plants and is used pharmacologically as a sympathomimetic. ... Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic …
Pentolinium
Pentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.
Approved
Matched Description: … Pentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension …
Chlorquinaldol
Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. It was marketed in the 1950s as an iodine-free alternative which was also unrelated to sulfa drugs or hormones. Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene for the treatment...
Approved
Matched Description: … Chlorquinaldol was used historically as a topical antiseptic under the trade name Sterosan. ... Chlorquinaldol is currently approved by the European Medicines Agency as a combination tablet with promestriene …
Selenious acid
Selenious acid is the acid form of sodium selenite, a form of selenium .
Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … It is a cofactor metabolic enzyme regulation. ... Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. ... Selenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative …
Flavin adenine dinucleotide
A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
Approved
Matched Description: … A condensation product of riboflavin and adenosine diphosphate. …
Zinc sulfate, unspecified form
Zinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888]
Approved
Experimental
Matched Description: … Zinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888] …
Valoctocogene roxaparvovec
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Description: … [L43282] The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes ... [L43292] Hemophilia A treatments such as prophylactic regimens of exogenous factor VIII or [emicizumab ... roxaparvovec was approved by EMA in September 2022 and is indicated for the treatment of severe hemophilia A. …
Nonoxynol-9
Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams,...
Approved
Withdrawn
Matched Description: … Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Micronomicin
Micronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina.
Approved
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Urokinase
Urokinase is an endogenous peptide that is cleaved in the presence of plasmin between lysine 158 and isoleucine 159 to yield active urokinase. Urokinase remains connected between these 2 chains by a sulfhydryl bond. Urokinase was granted FDA approval on 16 January 1978.
Approved
Investigational
Withdrawn
Matched Description: … [A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond. …
Physostigmine
A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.
Approved
Investigational
Matched Description: … A cholinesterase inhibitor that is rapidly absorbed through membranes. …
Aminocaproic acid
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Emicizumab
Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation …
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Description: … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced ... by recombinant DNA technology in a Pichia pastoris expression system. ... Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. …
Sodium aurothiomalate
Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL. It is most effective in active progressive rheumatoid arthritis and of little or no value in...
Approved
Investigational
Matched Description: … Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects ... Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold …
Ethylhexyl methoxycrylene
Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting with both the singlet and triplet states . It returns UV filters to their ground states without absorbing sunlight . It is used as a solvent for crystalline UV filters and is easily emulsified and suitable...
Approved
Experimental
Matched Description: … Ethylhexyl methoxycrylene is a photostabilizer that preserves the effectiveness of UV filters by interacting ... It is used as a solvent for crystalline UV filters and is easily emulsified and suitable for use in various …
Displaying drugs 451 - 475 of 11573 in total