Displaying drugs 201 - 225 of 12572 in total
Sildenafil
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … and effective treatment for erectile dysfunction and since its formal approval for medical use in the ... being serendipitously indicated for treating erectile dysfunction in the late 1980s [A175732]. ... public in 1998 [A175732], continues to see millions of prescriptions written for it internationally. …
Matched Mixtures name: … DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOXIL 30/50 MG FILM KAPLI TABLET, 3 FILM KAPLI TABLET …
Matched Categories: … Drugs Used in Erectile Dysfunction …
Matched Products: … Managra F/C Tablet 50mg ... Managra F/C Tablet 100mg ... Sildenafil for Oral Suspension …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … and effective treatment for erectile dysfunction and since its formal approval for medical use in the ... being serendipitously indicated for treating erectile dysfunction in the late 1980s [A175732]. ... public in 1998 [A175732], continues to see millions of prescriptions written for it internationally. …
Matched Mixtures name: … DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET ... DAPOXIL 30/50 MG FILM KAPLI TABLET, 3 FILM KAPLI TABLET …
Matched Categories: … Drugs Used in Erectile Dysfunction …
Matched Products: … Managra F/C Tablet 50mg ... Managra F/C Tablet 100mg ... Sildenafil for Oral Suspension …
Calcium glycerophosphate
Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Iupac: … calcium 2-(phosphonooxy)propane-1,3-diol …
Matched Description: … as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings ... calcium glycerophosphate promotes plaque-pH buffering, elevation of plaque [DB01373] and phosphate levels ... It is also present in dental or oral hygiene products due to its cariostatic effects. …
Matched Mixtures name: … Somarexin and C 1000 ... Alsimine W Vitamins A D …
Matched Description: … as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings ... calcium glycerophosphate promotes plaque-pH buffering, elevation of plaque [DB01373] and phosphate levels ... It is also present in dental or oral hygiene products due to its cariostatic effects. …
Matched Mixtures name: … Somarexin and C 1000 ... Alsimine W Vitamins A D …
Tryptophan
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Synonyms: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... L-β-3-indolylalanine ... (S)-α-amino-1H-indole-3-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Description: … An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults ... It is a precursor of indole alkaloids in plants. ... It can be a precursor to niacin, albeit inefficiently, in mammals. …
Matched Mixtures name: … Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) ... 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose ... AMINOMIX 3 SOLÜSYON, 1000 ML …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Description: … An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults ... It is a precursor of indole alkaloids in plants. ... It can be a precursor to niacin, albeit inefficiently, in mammals. …
Matched Mixtures name: … Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) ... 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose ... AMINOMIX 3 SOLÜSYON, 1000 ML …
Aminophenazone
Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests to measure the cytochrome P-450 metabolic activity in liver function tests. The FDA suspended the use of aminophenazone due to its association...
Approved
Withdrawn
Matched Synonyms: … 1,5-Dimethyl-4-dimethylamino-2-phenyl-3-pyrazolone ... 3-Keto-1,5-dimethyl-4-dimethylamino-2-phenyl-2,3-dihydropyrazole ... 4-(Dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … a risk of agranulocytosis. ... In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests ... to measure the cytochrome P-450 metabolic activity in liver function tests. …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Iupac: … 4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Description: … a risk of agranulocytosis. ... In biomedical applications, radiolabelled (13C-labeled) aminophenazone has been used in breath tests ... to measure the cytochrome P-450 metabolic activity in liver function tests. …
Matched Categories: … Non COX-2 selective NSAIDS …
Epinephrine
Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Synonyms: … 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol …
Matched Description: … Dosage delivery routes for epinephrine include intravenous, inhalation, nebulization, intramuscular injection ... glands that can also be used as a drug due to its various important functions. ... Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal …
Matched Salts cas: … 51-42-3 ... 55-31-2 …
Matched Mixtures name: … Xilonibsa 2% Solution for injection ... XILONIBSA Solution for Injection 2% 1:80000 ... LOCANEST-A 40 MG/2ML + 0,025/2ML ENJEKSİYONLUK ÇÖZELTİ, 20 ADET …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Sympathomimetics in Glaucoma Therapy ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists ... Drugs for Obstructive Airway Diseases …
Matched Products: … Epi E-Z Pen - Liquid - 0.3mg/0.3ml ... Gingi-pak Max Z-twist No 3 ... Gingi-pak Max Soft-twist No 3 …
Matched Iupac: … 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol …
Matched Description: … Dosage delivery routes for epinephrine include intravenous, inhalation, nebulization, intramuscular injection ... glands that can also be used as a drug due to its various important functions. ... Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal …
Matched Salts cas: … 51-42-3 ... 55-31-2 …
Matched Mixtures name: … Xilonibsa 2% Solution for injection ... XILONIBSA Solution for Injection 2% 1:80000 ... LOCANEST-A 40 MG/2ML + 0,025/2ML ENJEKSİYONLUK ÇÖZELTİ, 20 ADET …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Sympathomimetics in Glaucoma Therapy ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists ... Drugs for Obstructive Airway Diseases …
Matched Products: … Epi E-Z Pen - Liquid - 0.3mg/0.3ml ... Gingi-pak Max Z-twist No 3 ... Gingi-pak Max Soft-twist No 3 …
Perphenazine
An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Approved
Matched Synonyms: … 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol ... 2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine ... 4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … Etrafon A Tab ... Etrafon F Tab ... Apo Peram Tab 3-15 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … โมนาซีน-2 ... โปราซิน 2 ... เพอร์นาซีน 2 มก. …
Matched Iupac: … 2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethan-1-ol …
Matched Mixtures name: … Etrafon A Tab ... Etrafon F Tab ... Apo Peram Tab 3-15 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … โมนาซีน-2 ... โปราซิน 2 ... เพอร์นาซีน 2 มก. …
Darifenacin
Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence.
Darifenacin blocks M3 muscarinic acetylcholine receptors, which mediate bladder muscle contractions. This block reduces the urgency to urinate and so it should not be used in people with urinary retention.
It is unknown if M3 receptor selectivity is clinically...
Approved
Investigational
Matched Synonyms: … (S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-α,α-diphenyl-3-pyrrolidineacetamide …
Matched Iupac: … 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide …
Matched Description: … Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. ... This block reduces the urgency to urinate and so it should not be used in people with urinary retention ... It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Urinary Frequency and Incontinence …
Matched Iupac: … 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide …
Matched Description: … Darifenacin (Enablex®, Novartis) is a medication used to treat urinary incontinence. ... This block reduces the urgency to urinate and so it should not be used in people with urinary retention ... It is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Urinary Frequency and Incontinence …
Fluphenazine
A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Synonyms: … 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine ... 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol ... 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … A phenothiazine used in the treatment of psychoses. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Fluphenazine 2 Tab 2mg ... PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … A phenothiazine used in the treatment of psychoses. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Fluphenazine 2 Tab 2mg ... PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …
Periciazine
Periciazine is a phenothiazine of the piperidine group. It has been shown to reduce pathologic arousal and affective tension in some psychotic patients, while the symptoms of abnormal mental integration are relatively unaffected. It is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine...
Approved
Investigational
Matched Synonyms: … 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine ... 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine ... 10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Matched Description: … It is used as an adjunctive medication in some psychotic patients, for the control of residual prevailing ... Periciazine is a phenothiazine of the piperidine group. ... what has been described as a central adrenergic blockade. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Matched Description: … It is used as an adjunctive medication in some psychotic patients, for the control of residual prevailing ... Periciazine is a phenothiazine of the piperidine group. ... what has been described as a central adrenergic blockade. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Trimebutine
Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI...
Approved
Matched Synonyms: … 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoat …
Matched Iupac: … 2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate …
Matched Description: … Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international ... It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility ... Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Matched Products: … DEBRIDAT FOR ORAL SUSPENSION ... DEBRIDAT 100 MG TABLET, 20 ADET ... DEBRUTIN 100 MG TABLET, 20 ADET …
Matched Iupac: … 2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate …
Matched Description: … Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international ... It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility ... Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal …
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Matched Products: … DEBRIDAT FOR ORAL SUSPENSION ... DEBRIDAT 100 MG TABLET, 20 ADET ... DEBRUTIN 100 MG TABLET, 20 ADET …
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with …
Matched Description: … This decision is based on positive results demonstrated in 2 Phase 3 trials, B-SIMPLE 4 and B-SIMPLE ... 2, where reduced lesion counts were observed with once-a-day uses of berdazimer. ... [A262960] Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, …
Matched Description: … This decision is based on positive results demonstrated in 2 Phase 3 trials, B-SIMPLE 4 and B-SIMPLE ... 2, where reduced lesion counts were observed with once-a-day uses of berdazimer. ... [A262960] Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, …
Betibeglogene autotemcel
Betibeglogene autotemcel is an autologous gene therapy that adds functional copies of the β-globin gene (βA-T87Q-globin) to hematopoietic stem cells in order to treat β-thalassemia. β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. This affects...
Approved
Investigational
Matched Description: … [L42940] BB305 LVV encodes βA-T87Q-globin, compensating for the lack of β-globin in these ... This affects hemoglobin levels, and in patients with severe forms of this disease, long-term red cell ... [L42940] β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a …
Dienogest
Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Synonyms: … 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one ... 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile …
Matched Iupac: … 2-[(10S,11S,14R,15S)-14-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-1,6-dien-14-yl] …
Matched Description: … It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination ... for endometriosis to alleviate painful symptoms of endometriosis and reduce endometriotic lesions [A20330 ... It is a derivative of 19-nortestosterone and has antiandrogenic properties. …
Matched Mixtures name: … VELBIENNE® 20 ... VELBIENNE® 20 ... LAFAMME 2/2MG …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Products: … DIENOGEST E ETINILESTRADIOLO DOC ... Aridya 2 mg Tabletten ... DIENOGEST 2 MG …
Matched Iupac: … 2-[(10S,11S,14R,15S)-14-hydroxy-15-methyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-1,6-dien-14-yl] …
Matched Description: … It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination ... for endometriosis to alleviate painful symptoms of endometriosis and reduce endometriotic lesions [A20330 ... It is a derivative of 19-nortestosterone and has antiandrogenic properties. …
Matched Mixtures name: … VELBIENNE® 20 ... VELBIENNE® 20 ... LAFAMME 2/2MG …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Products: … DIENOGEST E ETINILESTRADIOLO DOC ... Aridya 2 mg Tabletten ... DIENOGEST 2 MG …
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug ... bowel syndrome (IBS) in women. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Functional Gastrointestinal Disorders ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug ... bowel syndrome (IBS) in women. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Functional Gastrointestinal Disorders ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Rofecoxib
Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Synonyms: … 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone ... 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and ... The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. ... Rofecoxib is a solid. This compound belongs to the stilbenes. …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one …
Matched Description: … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and ... The proteins that rofecoxib target include elastin and prostaglandin G/H synthase 2. ... Rofecoxib is a solid. This compound belongs to the stilbenes. …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Ribavirin
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Synonyms: … 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide ... 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … in patients with genotype 2 and 3 [A19626]. ... In HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] ... It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. …
Matched Categories: … Treatments for Hepatitis C ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Antivirals for treatment of HCV infections …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … in patients with genotype 2 and 3 [A19626]. ... In HCV genotye 1/2/3/4/5/6 patients, ribavirin can be used in combination therapy involving [DB09102] ... It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. …
Matched Categories: … Treatments for Hepatitis C ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Antivirals for treatment of HCV infections …
Phenobarbital
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Description: … A barbituric acid derivative that acts as a nonselective central nervous system depressant. …
Matched Mixtures name: … Phenaphen No 3 Cap ... Phenaphen No 2 Cap ... Phenaphen No.3 Cap …
Matched Categories: … Medications that reduce magnesium levels ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Matched Mixtures name: … Phenaphen No 3 Cap ... Phenaphen No 2 Cap ... Phenaphen No.3 Cap …
Matched Categories: … Medications that reduce magnesium levels ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
2-mercaptobenzothiazole
Approved
Experimental
Vet approved
Matched Synonyms: … 2-MBT ... 2-Benzothiazolethiol ... Benzothiazole-2-thiol …
Matched Name: … 2-mercaptobenzothiazole …
Matched Iupac: … 2,3-dihydro-1,3-benzothiazole-2-thione …
Matched Salts name: … Sodium 2-mercaptobenzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Name: … 2-mercaptobenzothiazole …
Matched Iupac: … 2,3-dihydro-1,3-benzothiazole-2-thione …
Matched Salts name: … Sodium 2-mercaptobenzothiazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Entrectinib
Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Synonyms: … N-[5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methylpiperazin-1-yl)-2-(oxan-4-ylamino)benzamide …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … [L8081] It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic ... Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein ... [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … N-{5-[(3,5-difluorophenyl)methyl]-1H-indazol-3-yl}-4-(4-methylpiperazin-1-yl)-2-[(oxan-4-yl)amino]benzamide …
Matched Description: … [L8081] It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic ... Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein ... [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Clenbuterol
A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.
Approved
Investigational
Vet approved
Matched Synonyms: … 1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanol …
Matched Iupac: … 1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethan-1-ol …
Matched Description: … It is used as a bronchodilator in asthma. ... A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. …
Matched Mixtures name: … OXOLVAN C ... BRONCOCHEM® F JARABE ADULTOS ... BRONCOCHEM® F JARABE ADULTOS …
Matched Categories: … Adrenergics for Systemic Use ... Adrenergic beta-2 Receptor Agonists ... Drugs for Obstructive Airway Diseases ... Selective Beta 2-adrenergic Agonists …
Matched Iupac: … 1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethan-1-ol …
Matched Description: … It is used as a bronchodilator in asthma. ... A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. …
Matched Mixtures name: … OXOLVAN C ... BRONCOCHEM® F JARABE ADULTOS ... BRONCOCHEM® F JARABE ADULTOS …
Matched Categories: … Adrenergics for Systemic Use ... Adrenergic beta-2 Receptor Agonists ... Drugs for Obstructive Airway Diseases ... Selective Beta 2-adrenergic Agonists …
Bexarotene
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Synonyms: … 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid ... p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid ... 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid …
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid …
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. ... Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Retinoids for cancer treatment …
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid …
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. ... Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Retinoids for cancer treatment …
Acenocoumarol
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one ... 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one ... 3-(alpha-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … Acenocoumarol is a coumarin derivative used as an anticoagulant. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … Acenocoumarol is a coumarin derivative used as an anticoagulant. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Pimecrolimus
Pimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007. It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Approved
Investigational
Matched Iupac: … (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-12-[(1E)-1-[(1R,3R,4S)-4-chloro-3-methoxycyclohexyl]prop ... -1-en-2-yl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo …
Matched Description: … It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema). ... It is now promoted in Canada by Galderma since early 2007. …
Matched Categories: … Agents for Dermatitis, Excluding Corticosteroids …
Matched Description: … It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema). ... It is now promoted in Canada by Galderma since early 2007. …
Matched Categories: … Agents for Dermatitis, Excluding Corticosteroids …
Theophylline
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly...
Approved
Matched Description: … Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for ... A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac ... Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and …
Matched Mixtures name: … TUSBRON-A JARABE ... Theophylline in Dextrose ... Theophylline in Dextrose …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Obstructive Airway Diseases ... Medications that reduce magnesium levels ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … Theophylline in Dextrose ... PIRAZMEN 250 MG TABLET, 20 TABLET ... FILINSEL 24 MG/ML IV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 10 ML X 3 AMPUL …
Matched Mixtures name: … TUSBRON-A JARABE ... Theophylline in Dextrose ... Theophylline in Dextrose …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs for Obstructive Airway Diseases ... Medications that reduce magnesium levels ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … Theophylline in Dextrose ... PIRAZMEN 250 MG TABLET, 20 TABLET ... FILINSEL 24 MG/ML IV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 10 ML X 3 AMPUL …
Chlormezanone
A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide ... 2-(p-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide …
Matched Iupac: … 2-(4-chlorophenyl)-3-methyl-1lambda6,3-thiazinane-1,1,4-trione …
Matched Description: … A non-benzodiazepine that is used in the management of anxiety. ... It has been suggested for use in the treatment of muscle spasm. …
Matched Iupac: … 2-(4-chlorophenyl)-3-methyl-1lambda6,3-thiazinane-1,1,4-trione …
Matched Description: … A non-benzodiazepine that is used in the management of anxiety. ... It has been suggested for use in the treatment of muscle spasm. …
Displaying drugs 201 - 225 of 12572 in total