Displaying drugs 26 - 50 of 54 in total
Brodalumab
Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-severe plaque psoriasis.
Approved
Investigational
Minocycline
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Beta vulgaris pollen
Beta vulgaris pollen is the pollen of the Beta vulgaris plant. Beta vulgaris pollen is mainly used in allergenic testing.
Approved
Matched Name: … Beta vulgaris pollen …
Matched Description: … Beta vulgaris pollen is the pollen of the Beta vulgaris plant. ... Beta vulgaris pollen is mainly used in allergenic testing. …
Matched Description: … Beta vulgaris pollen is the pollen of the Beta vulgaris plant. ... Beta vulgaris pollen is mainly used in allergenic testing. …
Azelaic acid
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is also produced by Malassezia furfur, also known as Pityrosporum ovale, which is a species of fungus that is normally found on human skin. Azelaic acid is effective against a number of skin conditions, such...
Approved
Matched Synonyms: … Anchoic acid ... Azelaic acid ... Lepargylic acid …
Matched Name: … Azelaic acid …
Matched Iupac: … nonanedioic acid …
Matched Description: … Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. ... Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied …
Matched Mixtures name: … Azelaic Acid 15% / Niacinamide 4% ... 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … azelaic acid …
Matched Products: … Azelaic Acid ... Azelaic Acid Gel …
Matched Name: … Azelaic acid …
Matched Iupac: … nonanedioic acid …
Matched Description: … Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. ... Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied …
Matched Mixtures name: … Azelaic Acid 15% / Niacinamide 4% ... 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … azelaic acid …
Matched Products: … Azelaic Acid ... Azelaic Acid Gel …
Northern bluefin tuna
Northern bluefin tuna allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Thunnus vulgaris flesh ... Thynnus vulgaris flesh …
Atlantic halibut
Atlantic halibut allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Hippoglossus vulgaris flesh …
Atlantic mackerel
Atlantic mackerel allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Scomber vulgaris flesh …
Clascoterone
Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. It binds to androgen receptors with high affinity. By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland proliferation, excess sebum production, and...
Approved
Investigational
Matched Description: … A218846] In August 2020, FDA approved clascoterone for the first-in-class topical treatment of acne (acne vulgaris …
Mezlocillin
Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Matched Synonyms: … 6β-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid ... oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Carindacillin
Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Synonyms: … 6β-{2-[(2,3-dihydro-1H-inden-5-yloxy)carbonyl]-2-phenylacetamido}-2,2-dimethylpenam-3α-carboxylic acid …
Matched Iupac: … yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … yloxy)-3-oxo-2-phenylpropanamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Benzoyl peroxide
Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Products: … Panoxyl Wash 10 - Liq Top 10% ... Panoxyl Aquagel 20 - Gel Top 20% ... SLMD BP Body Wash …
Spironolactone
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne vulgaris …
Netilmicin
Netilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. Netilmicin inhibits protein synthesis in susceptible organisms by binding to the bacterial 30S ribosomal subunit and interfering with mRNA binding and the acceptor tRNA site. The bactericidal effect...
Approved
Investigational
Acetyl sulfisoxazole
Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Matched Description: … , which is the precursor of folic acid. ... ester of _sulfisoxazole_, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid ... This process causes an inhibition of bacterial folic acid synthesis and de novo synthesis of purines …
Cantharidin
Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that is produced as an oral fluid in the alimentary canal of the male blister beetle.[A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory...
Approved
Investigational
Matched Mixtures name: … Cantharidin 1% / Podophyllum Resin 5% / Salicylic Acid 30% …
Rituximab
Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Bambusa vulgaris top
Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Bambusa Vulgaris Leaf/stem Extract ... Bambusa Vulgaris Top Extract ... Bamboo Top …
Matched Name: … Bambusa vulgaris top …
Matched Description: … Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Name: … Bambusa vulgaris top …
Matched Description: … Bambusa vulgaris top is a plant/plant extract used in some OTC (over-the-counter) products. …
Picolinic acid
PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. PCL-016 plays a key role in zinc transport. As a...
Investigational
Matched Name: … Picolinic acid …
Matched Iupac: … pyridine-2-carboxylic acid …
Matched Description: … as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body ... Acne vulgaris, herpes and other viral infections therefore pose potential therapeutic targets of PCL- ... PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. …
Matched Iupac: … pyridine-2-carboxylic acid …
Matched Description: … as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body ... Acne vulgaris, herpes and other viral infections therefore pose potential therapeutic targets of PCL- ... PCL-016 or Picolinic acid drug substance is a pyridine carboxylate metabolite of tryptophan. …
Prunus armeniaca seed
Prunus armeniaca seed is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Armeniaca Vulgaris Seed …
Olumacostat glasaretil
Olumacostat glasaretil has been used in trials studying the treatment of Acne Vulgaris.
Investigational
Matched Description: … Olumacostat glasaretil has been used in trials studying the treatment of Acne Vulgaris. …
Ianalumab
Ianalumab is under investigation in clinical trial NCT01930175 (Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris).
Investigational
Matched Description: … investigation in clinical trial NCT01930175 (Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris …
Nadifloxacin
Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
Investigational
Matched Iupac: … hydroxypiperidin-1-yl)-12-methyl-4-oxo-1-azatricyclo[7.3.1.0⁵,¹³]trideca-2,5,7,9(13)-tetraene-3-carboxylic acid …
Matched Description: … Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris. …
Matched Description: … Nadifloxacin has been used in trials studying the treatment of Acne Vulgaris. …
PF-05175157
PF-05175157 has been used in trials studying the basic science and treatment of Acne Vulgaris, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus Type 2, and Diabetes Mellitus, Type 2, among others.
Investigational
Matched Description: … PF-05175157 has been used in trials studying the basic science and treatment of Acne Vulgaris, Diabetes …
Displaying drugs 26 - 50 of 54 in total