Displaying drugs 26 - 50 of 59 in total
Natalizumab
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Description: … Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Dabigatran etexilate
Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran.[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. In contrast to warfarin, because its anticoagulant effects...
Approved
Matched Description: … Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin …
Matched Categories: … Blood and Blood Forming Organs …
Matched Categories: … Blood and Blood Forming Organs …
Porphobilinogen deaminase, human recombinant
Investigational
Matched Synonyms: … Hydroxymethylbilane synthase, recombinant human erythyroid isoform ... Porphobilinogen deaminase, recombinant human erythroid isoform ... Recombinant human porphobilinogen deaminase, erythroid isoform …
Matched Name: … Porphobilinogen deaminase, human recombinant …
Matched Name: … Porphobilinogen deaminase, human recombinant …
Lenvervimab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(hepatitis b surface antigen) (human monoclonal gc1102 .gamma.1-chain), disulfide ... Recombinant hepatitis B human immunoglobulin ... Hepatitis B virus neutralizing human monoclonal antibody …
Baloramotide
Investigational
Matched Synonyms: … L antigen family member 2, recombinant ... Glycyl-l-prolyl-human cancer/testis antigen 1 (autoimmunogenic cancer/testis antigen ny-eso-1, l antigen ... Cancer/testis antigen 1, recombinant …
RP-A501
RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9) capsid containing the human LAMP2B transgene (AAV9:LAMP2B), which encodes lysosome-associated membrane protein 2 (LAMP-2). It is being investigated for Danon disease.
Investigational
Matched Synonyms: … B transgene (AAV9.LAMP2B) ... Adeno-associated virus serotype 9 vector containing the human lysosome-associated membrane glycoprotein 2 isoform …
Matched Description: … RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9 …
Matched Description: … RP-A501 is a gene therapy product consisting of a recombinant adeno-associated virus serotype 9 (rAAV9 …
Volrubigene ralaparvovec
Volrubigene ralaparvovec is under investigation in clinical trial NCT03223194 (Gene Transfer Clinical Study in Crigler-najjar Syndrome).
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated viral vector, serotype 8, expressing the 1A1 isoform of …
Recifercept
Investigational
Matched Synonyms: … Fibroblast growth factor receptor 3 (recombinant human soluble isoform ta-46) ... Recombinant human fibroblast growth factor receptor 3 ... Human fibroblast growth factor receptor 3 (fgfr-3, cd333) (1-336)-(401-413) fragment (1-349) (soluble isoform …
Dapiclermin
Dapiclermin is a recombinant ciliary neurotrophic factor.
Investigational
Matched Synonyms: … 2-185-ciliary neurotrophic factor (17 -alanine,63-arginine) (human isoform axokine) ... 2-185-(17-alanine,63-agrinine)ciliary neurotrophic factor-(2,185)-peptide (human isoform axokine) …
Matched Description: … Dapiclermin is a recombinant ciliary neurotrophic factor. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Dapiclermin is a recombinant ciliary neurotrophic factor. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Canoctakin
Investigational
Matched Synonyms: … -tetra-l-lysine)human interleukin 8 precursor-(34-99)- peptide anti-inflammatory ... Interleukin 8 (synthetic human clone dncxcl8 increased-glycosaminoglycan binding isoform pa401) ... Recombinant dna derived, human interleukin 8 (cxcl8) mutein, produced in escherichia coli: (44,48,97,98 …
Denenicokin
Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational
Matched Synonyms: … L-METHIONYL(HUMAN INTERLEUKIN-21) ... IL-21 recombinant ... Recombinant human IL-21 …
Botaretigene sparoparvovec
Investigational
Matched Synonyms: … DNA (RECOMBINANT PSEUDOTYPED ADENO-ASSOCIATED VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER ... FRAGMENT-REGULATED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS …
rhMBL
rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL is a 400-700kDa oligomer made of 3 identical 32kDa peptide...
Investigational
Matched Synonyms: … Recombinant human mannan-binding protein ... Recombinant human mannose-binding lectin …
Matched Description: … rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections …
Matched Description: … rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections …
Lucatumumab
Investigational
Matched Synonyms: … Recombinant anti-CD40 monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
NGN-401
NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 (MECP2). Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome.
Investigational
Matched Synonyms: … Recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence ... , complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 (MECP2) …
Matched Description: … NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA ... generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding …
Matched Description: … NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA ... generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding …
Zelpultide alfa
Zelpultide alfa is a recombinant human surfactant protein D.
Investigational
Matched Synonyms: … RECOMBINANT SP-D ... recombinant human surfactant protein D ... RECOMBINANT HUMAN PULMONARY SURFACTANT-ASSOCIATED PROTEIN D …
Matched Description: … Zelpultide alfa is a recombinant human surfactant protein D. …
Matched Description: … Zelpultide alfa is a recombinant human surfactant protein D. …
Eflepedocokin alfa
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Synonyms: … RECOMBINANT HUMAN INTERLEUKIN-22 IGG2-FC ... F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO …
Matched Description: … Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
MEDI6012
Recombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction).
Investigational
Matched Synonyms: … Recombinant human lecithin:cholesterol acyltransferase …
Matched Description: … Recombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 ... (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction …
Matched Description: … Recombinant human lecithin:cholesterol acyltransferase is under investigation in clinical trial NCT03578809 ... (A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction …
Simtuzumab
Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis.
Investigational
Matched Synonyms: … Recombinant humanized anti-LOXL2 monoclonal antibody …
Matched Description: … Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis. ... Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis. ... Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Depelestat
Investigational
Matched Synonyms: … Proteinase inhibitor m/nei (synthetic human) ... Recombinant human neutrophil inhibitor (hne) ... Human recombinant neutrophil elastase inhibitor, homologue of the second kunitz domain of inter-alpha-trypsin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Acimtamig
Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.
Investigational
Matched Synonyms: … tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct ... region) fusion protein with peptide linker (GGS)3 fusion protein with immunoglobulin anti-(human CD30 antigen …
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
GYM329
GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH-dependent manner
Investigational
Matched Synonyms: … recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin in a pH dependent …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Matched Description: … GYM329 is a recombinant humanized IgG1-based monoclonal antibody which binds to human latent myostatin …
Retlirafusp alfa
Investigational
Matched Synonyms: … linker ((ggggs)4g) fusion protein with 20-136-type II transforming growth factor .beta. receptor (human isoform …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins …
GTB-3550
GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of Interleukin 15 (IL-15).
Investigational
Matched Synonyms: … single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 …
Matched Description: … GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable ... regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of Interleukin …
Matched Description: … GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable ... regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of Interleukin …
Aldafermin
Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study in Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)).
Investigational
Matched Synonyms: … Engineered variant of recombinant human fibroblast growth factor 19 …
Matched Description: … Double-blind, Placebo-controlled, Multi-center Study in Subjects With Nonalcoholic Steatohepatitis and ... Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Double-blind, Placebo-controlled, Multi-center Study in Subjects With Nonalcoholic Steatohepatitis and ... Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Displaying drugs 26 - 50 of 59 in total