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Displaying drugs 601 - 625 of 695 in total
Experimental
Matched Name: … N-sulfo-flavin mononucleotide …
Investigational
Matched Name: … Albumin-stabilized nanoparticle (130 nm) …
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … chain), disulfide with human-mus musculus monoclonal BAN2401 light chain, dimer ... Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy …
Matched Description: … recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … (human-mus musculus monoclonal m9346a heavy chain), disulfide with human-mus musculus monoclonal m9346a …
Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … .4-chain), disulfide with human-mus musculus monoclonal ak117 .kappa. ... Immunoglobulin g4 (225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal ak117 .gamma …
Experimental
Matched Name: … O2-Sulfo-Glucuronic Acid …
Experimental
Matched Synonyms: … O-sulfo-L-serine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Synonyms: … WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 LIGHT CHAIN, DIMER ... WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18/CHO LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(GANGLIOSIDE GD2) (HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 HEAVY CHAIN), DISULFIDE …
Matched Description: … Despite a high clinical response seen after first-line treatment, the complete eradication of neuroblastoma ... It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the ... constant regions of human IgG1 heavy-chain and kappa light-chain. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Investigational
Matched Synonyms: … pbp1510 .gamma.1-chain), disulfide with human-mus musculus monoclonal pbp1510 .kappa. ... Immunoglobulin g1, anti-(human pancreatic adenocarcinoma up-regulated factor) (human-mus musculus monoclonal …
Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Investigational
Matched Synonyms: … WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA. ... IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Gemfibrozil is a fibric acid agent, similar to clofibrate, used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. Gemfibrozil was granted FDA approval on 21...
Approved
Matched Synonyms: … 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid …
Matched Description: … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias ... responded adequately to weight loss, diet, exercise, and other medications. ... [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not …
Matched Categories: … Drug-Related Side Effects and Adverse Reactions ... Metabolic Side Effects of Drugs and Substances …
Carya tomentosa pollen is the pollen of the Carya tomentosa plant. Carya tomentosa pollen is mainly used in allergenic testing.
Approved
Matched Synonyms: … Carya alba pollen …
Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.
Approved
Investigational
Withdrawn
Matched International brands: … Resulin
Matched Description: … It was superseded by [pioglitazone] and [rosiglitazone]. …
Matched Categories: … Alimentary Tract and Metabolism ... Sulfur Compounds …
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched International brands: … Resof
Matched Description: … for its high replicative rate and genetic diversity [A19594]. ... count, and neuropsychiatric effects [A19635]. ... categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and
Matched Mixtures name: … Ledipasvir and Sofosbuvir ... Sofosbuvir and Velpatasvir …
Matched Categories: … sofosbuvir and ledipasvir ... sofosbuvir and velpatasvir ... Nucleic Acids, Nucleotides, and Nucleosides ... sofosbuvir, velpatasvir and voxilaprevir …
Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(multiple sclerosis-associated retrovirus viral envelope protein) (human-mus ... musculus monoclonal gnbac1 heavy chain), disulfide with human-mus musculus monoclonal gnbac1 kappa-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … hlx10 .gamma.4-chain), disulfide with human-mus musculus monoclonal hlx10 .kappa. ... Immunoglobulin g4 (228-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal …
Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as...
Approved
Vet approved
Matched Description: … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... paclitaxel and encequidar …
Matched Products: … Paclitaxel Protein Bound Particles Albumin Bound ... Paclitaxel protein-bound particles for injectable suspension (albumin-bound) ... Paclitaxel Protein-Bound Particles for Injectable Suspension (Albumin-Bound) …
Investigational
Matched Synonyms: … .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa. ... Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 Plus Bendamustine vs. Bendamustine in Relapsed Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human cd antigen cd37) (synthetic human-mus musculus fragment tru-016), dimer …
Matched Description: … Otlertuzumab is under investigation in clinical trial NCT01188681 (Safety and Efficacy Study of TRU-016 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … with human-mus musculus monoclonal c2g4 .kappa. ... IMMUNOGLOBULIN G1-KAPPA, ANTI-(EBOLAVIRUS GLYCOPROTEIN) CHIMERIC HOMO SAPIENS-MUS MUSCULUS MONOCLONAL ... ANTIBODY: .GAMMA.1 HEAVY CHAIN (1-451) (MUS MUSCULUS VH (IGHV6-6*02 (95%) (IGHD)-IGHJ4*01 (94%)) (8.10.12 …
Investigational
Matched Synonyms: … 230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein TNFSF14) (human-Mus ... musculus monoclonal SAR252067 γ4-chain), disulfide with human-Mus musculus monoclonal SAR252067 .kappa …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Azadirachta indica leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Bead Tree Leaf …
Investigational
Matched Synonyms: … 267-glutamic acid,de-C-terminal lysine), anti-(human tumor necrosis factor receptor TNFRSF9) (human-mus ... musculus monoclonal lvgn6051 .hamma.1-chain), disulfide with human-mus musculus monoclonal lvgn6051 …
Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Description: … or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and ... Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular …
Matched Mixtures name: … Albumin Human Diluent ... Plasma-Lyte 148 and dextrose ... Dextrose and Electrolyte No. 75 …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Walgreens Infants and Childrens Saline Nasal …
An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Synonyms: … -L-ARABINO-HEXOPYRANOSIDE ... -L-ARABINO-HEXOPYRANOSYL)OXY)-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-, (8S-CIS …
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Displaying drugs 601 - 625 of 695 in total