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Displaying drugs 51 - 75 of 1861 in total

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification ... coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and ... Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... Three domains are deleted from retavase - kringle-1, finger, and epidermal growth factor (EGF). …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated …
Matched Categories: … Medications that reduce magnesium levels ... Compounds used in a research, industrial, or household setting …

Padimate O

Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in ... It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... concentrations up to 8%, as regulated by the FDA [L2153]. …
Matched Mixtures name: … Sun and Ski Stick SPF 15 ... Aruba Aloe Lip Sunscreen and Moisturizer ... Phineas and Ferb Sun Smacker SPF 24 Berry Busted …
Matched Categories: … Hydrocarbons, Cyclic ... Compounds used in a research, industrial, or household setting …
Matched Products: … Green Tea and Ginkgo Moisturizer SPF 10 ... Hand and Body Lotion SPF 15 ... Medicated Lip Balm - Ont Top 8% …

ARGX-119

ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … targets and activates MuSK ... a fully humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically …
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …

Menotropins

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits ... It is used as a fertility medication that is injected either subcutaneously or intramuscularly. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Menopur Powder for Injection and Solvent 75 IU ... MENOPUR multidose 600IU Powder and Solvent for Solution for Injection ... MENOPUR multidose 1200IU Powder and Solvent for Solution for Injection …

Selenium Sulfide

Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Description: … is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and ... Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative ... tinea capitis, a fungal infection that is primarily a disease of preadolescent children. …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Topco Associates ... Head and Shoulders Itch ... Walgreens Dandruff and Conditioner Cleansing and Conditioning Anti-dandruff …

Synthetic camphor

Approved
Experimental
Matched Mixtures name: … Green Leaf Cbd Ultra Relief ... CAMPHOR (SYNTHETIC) and PHENOL ... Major Camphor and Phenol …
Matched Products: … Arthritis and Joint Pain Relief Thayers ... Soothe and Move Pain Relief Cream ... Weeks and Leo Medicated Vaporizing Steam …

Camphor

Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Description: … It is used topically as a skin antipruritic and as an anti-infective agent. ... When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often ... The FDA ruled that camphorated oil could not be marketed in the United States and that no product could …
Matched Mixtures name: … Green Leaf Cbd Joint and Muscle Pain Relief ... OFF Bite and Itch Relief First Aid Antiseptic ... Jack and Jill Rub …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics ... Hydrocarbons, Cyclic …
Matched Products: … Muscle and Joint HRX Pain Relieving ... Joints and Muscles Pain Relieving ... Earths Care Muscle and Joint Rub …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Description: … Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Hemophilia A …
Matched Products: … ADVATE 250IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 500IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 1000IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Eupatorium capillifolium pollen

Eupatorium capillifolium pollen is the pollen of the Eupatorium capillifolium plant. Eupatorium capillifolium pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Dog Fennel, Eastern Eupatorium capillifolium ... Pollens - Weeds and Garden Plants, Dog Fennel Eupatorium capillifolium …

Sodium fluorophosphate

Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Approved
Matched Mixtures name: … Mentadent Specialty Whitening Toothpaste and Polishing ... Hawaiian Airline EC with Colgate Toothbrush and Sun ... Topol Plus Whitening Tpt for Sensitive Teeth …
Matched Categories: … Alimentary Tract and Metabolism ... Phosphoric Acids ... Phosphorus Acids ... Phosphorus Compounds ... Compounds used in a research, industrial, or household setting …
Matched Products: … New Doctor Ag Plus Gold ... Schmidts MINT and BERRY KIDS TOOTH AND MOUTH ... Schmidts WATERMELON and STRAWBERRY KIDS TOOTH AND MOUTH …

DCVAC/OvCa

DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … and matured by TLR3 ligand _ex vivo_. ... DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells …

CHF5633

CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … ), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic ... CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). ... FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent ... of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines …
Matched Mixtures name: … BOSKA ... Top Care Flu and Sore Throat ... Vanquish Digital Headache …
Matched Categories: … Acetaminophen and Prodrugs ... codeine and paracetamol ... tramadol and paracetamol ... oxycodone and paracetamol ... dihydrocodeine and paracetamol …
Matched Products: … Uphamol 1000mg Powder (Honey and Lemon) ... Topco Arthritis 8 Hour ... Pain and Fever …

TN-201

TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.
Investigational
Matched Synonyms: … Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … promoter and the wild-type human MYBPC3 gene. ... TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific …

Capsaicin

Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent...
Approved
Matched Description: … Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, ... and patch preparations of various strengths; however, it may also be found in some dietary supplements ... The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated …
Matched Mixtures name: … Satohap Cool and Hot Pads ... Zostrix Hot and Cold Therapy System ... Cajun Hot Ice Muscle and Joint Pain Rub …
Matched Categories: … Basic Lotions and Liniments ... Capsaicin and Similar Agents ... Topical Products for Joint and Muscular Pain ... Hydrocarbons, Cyclic ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Products: … MINTED LEAF Heat Therapy Roll-On with Capsaicin and CBD ... Sherman and Clark Pain Relieving ... CareALL Arthritis and Muscle …

TPX-4589

TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … and linker-payload MC-VC-PAB-MMAE. ... TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 …

Beef

Beef allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Animal Products and Poultry Products, Beef Bovine spp. …

VOR33

VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …

Omalizumab

Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). IgE promotes the release of inflammatory mediators from mast cells and basophils during allergic and inflammatory reactions. By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its...
Approved
Investigational
Matched Description: … , and asthma. ... and inflammatory reactions. ... By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xolair 75mg Powder and Solvent for Solution for Injection ... XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Xolair 150mg Powder and Solvent for Solution for Injection …

Hydrocodone

Hydrocodone is a synthetic opioid derivative of codeine. It is commonly used in combination with acetaminophen to control moderate to severe pain. Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by dextromethorphan in current cough and cold formulations. Hydrocodone's more potent metabolite, hydromorphone...
Approved
Illicit
Investigational
Matched Description: … Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is ... by [dextromethorphan] in current cough and cold formulations. ... Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced …
Matched Mixtures name: … Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate and Acetaminophen …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... Hydrocarbons, Cyclic …
Matched Products: … Hydrocodone Bitartrate and Acetaminophen ... Hydrocodone Bitartrate And Acetaminophen …

Wormwood

Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Absinthe Flowering Top ... Absinthium Flowering Top ... Absinth Sagewort Flowering Top …
Matched Description: … It is not an approved drug. ... Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Products: … Seborrheic Dermatitis and Psoriasis ... Seborrheic Dermatitis and Psoriasis Cream …

Sunflower oil

Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Description: … It is not an approved drug. ... Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Products: … OrgaPlus Super Care Balm for combination and oi ly skin type 20g ... OrgaPlus Super Care Balm for combination and oi ly skin type 14g …

TN-401

TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational
Matched Synonyms: … A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …
Displaying drugs 51 - 75 of 1861 in total