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Displaying drugs 801 - 825 of 854 in total
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. …
Matched Products: … Esmolol Hydrochloride In Sodium Chloride …
Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido, as well as long-term complications such as osteoporosis . Newer dopamine receptor agonists such as quinagolide and DB00248 are...
Approved
Investigational
Matched Synonyms: … N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)sulfamide
Matched Description: … Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido ... Newer dopamine receptor agonists such as quinagolide and [DB00248] are shown to effectively inhibit prolactin ... Quinagolide exists as a racemate and its relevant clinical activity is mediated predominantly by the …
Matched Categories: … Genito Urinary System and Sex Hormones …
Cefalotin is a cephalosporin antibiotic.
Approved
Investigational
Vet approved
Matched Salts name: … Cefalotin sodium
Matched Products: … CEFALOTINA (SODICA)1 G FRASCO AMPOLLA …
Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Description: … Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and ... As folate analogs, levoleucovorin and leucovorin are both used to counteract the toxic effects of folic …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives ... sodium levofolinate …
Matched Products: … SODIO LEVOFOLINATO MEDAC …
Arabica coffee bean allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Coffea vulgaris seed …
Approved
Experimental
Matched Synonyms: … Amomum angustifolium oil …
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Approved
Investigational
Matched Description: … It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone …
Matched Salts name: … Cefonicid sodium
Matched Products: … CEFONICID SODICO
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … Amoxicillin Sodium and Potassium Clavulanate for Injection ... Amoxicillin Sodium and Potassium Clavulanate for Injection ... Amoxicillin Sodium and Potassium Clavulanate for Injection …
Matched Salts name: … Amoxicillin sodium
Matched Categories: … Alimentary Tract and Metabolism ... rabeprazole, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and clarithromycin ... omeprazole, amoxicillin and rifabutin ... rabeprazole, amoxicillin and metronidazole …
Matched Products: … AMOXICILLIN SODIUM ... AMOXICILLINA SODICA K24 PHARMACEUTICALS ... Nu-amoxi Sus 125/5ml …
Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
Investigational
Matched Synonyms: … anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused with human iduronate-2-sulfatase ... ) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC 2-AMINO ACID LINKER) FUSION PROTEIN WITH HUMAN IDURONATE-2-SULFATASE
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … Sodium 3-(3-tert-butyl-4-methoxy-5-{6­ [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 …
Matched Description: … categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... [DB00503] for genotype 1b and with [DB00811] for genotype 1a of Hepatitis C [L852]. ... recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and
Matched Salts name: … Dasabuvir sodium ... Dasabuvir sodium monohydrate …
Matched Categories: … dasabuvir, ombitasvir, paritaprevir and ritonavir …
Experimental
Matched Synonyms: … para-toluene sulfonate
AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … modified autologous cell therapy intended for the stable provision of functional human iduronate-2-sulfatase
Matched Description: … autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Description: … it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows …
Matched Products: … VULGAR 25 MG FILM TABLET, 4 FILM TABLET ... VULGAR 50 MG FILM TABLET, 4 FILM TABLET ... VULGAR 100 MG FILM TABLET, 4 FILM TABLET …
Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.
Investigational
Vet approved
Matched Synonyms: … Fenbendazole sulfoxide
Matched Description: … This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn. ... Oxfendazole is a sulfoxide metabolite of fenbendazole. …
Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like morphine and oxycodone. Fentanyl's high potency has also...
Approved
Illicit
Investigational
Vet approved
Matched Description: … Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia ... Label,L6598,L6601,L6604,L6607,L922,L6610,L6613] Fentanyl is related to other opioids like [morphine] and
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … PECFENT NASAL SPRAY SOLUTION 400 MCG/SPRAY ... PECFENT NASAL SPRAY SOLUTION 100 MCG/SPRAY ... FENTANYL MERCURY 100 MG/2 ML IV ENJEKSİYONLUK ÇÖZELTİ …
Experimental
Matched Name: … 2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate
Matched Iupac: … 2-(cycloheptylmethyl)-1,1-dioxo-1lambda6-benzothiophen-6-yl sulfamate
Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Mixtures name: … PIPERACILLIN SODIUM and TAZOBACTAM SODIUM ... PIPERACILLIN SODIUM and TAZOBACTAM SODIUM ... PIPERACILLIN SODIUM and TAZOBACTAM SODIUM
Matched Salts name: … Piperacillin sodium
Matched Products: … PIPERACILLINA SODICA
Taraxacum officinale leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Taraxacum Vulgare Leaf …
Investigational
Matched Synonyms: … -one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium
Experimental
Matched Name: … Tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate
Matched Iupac: … potassium (1R)-4-{[1,1'-biphenyl]-4-yl}-1-[bis(potassiooxy)phosphoryl]butane-1-sulfonate
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Salts name: … Dicloxacillin sodium ... Dicloxacillin sodium anhydrous …
Matched Products: … Dicloxacillin Sodium
Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and is produced by Streptomyces fradiae.[A229338,A230348] It may also be produced synthetically and is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. In terms of...
Approved
Matched Description: … Fosfomycin was discovered in 1969 by scientists at the Spanish Penicillin and Antibiotics Company and ... group and an epoxide ring. ... is active against both gram-positive and gram-negative bacteria. …
Matched Salts name: … Fosfomycin sodium
Matched Products: … FOSFOMYCIN SODIUM
Pisum sativum whole allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Pisum vulgare whole …
An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical...
Approved
Matched Description: … An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory ... Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine ... Throughout the late seventies and the eighties, important research initiatives developed stable mesalazine …
Matched Products: … sfRowasa Sulfite-Free Formulation …
Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis[L7303,L7315,L7318,L7321,L7324,L7327]. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA...
Approved
Matched Description: … analog antiviral used to treat herpes simplex, _Varicella zoster_, herpes zoster, herpes labialis, and ... Acyclovir is generally used first line in the treatment of these viruses and some products are indicated …
Matched Salts name: … Acyclovir sodium
Matched Categories: … Acyclovir and prodrug ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … Acyclovir Sodium ... Acyclovir Sodium Injection ... Acyclovir Sodium for Injection …
Displaying drugs 801 - 825 of 854 in total