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Displaying drugs 826 - 850 of 885 in total

Bosentan

Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Taro-bosentan …

Dexamethasone

Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and ... L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and ... Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one …
Matched Mixtures name: … Taro-ciprofloxacin/dexamethasone ... Neomycin and Polymyxin B Sulfates and Dexamethasone ... Neomycin Polymyxin B Sulfates and Dexamethasone …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Sex Hormones and Insulins ... dexamethasone and antibiotics ... dexamethasone and antiinfectives …
Matched Products: … Dexamethasone Sod Phos Inj 4mg/ml …

Mycophenolate mofetil

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Description: … Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified ... to prevent organ rejection after hepatic, renal, and cardiac transplants. ... [A180805] This drug is an immunosuppressant combined with drugs such as [Cyclosporine] and corticosteroids …
Matched Categories: … Mycophenolic Acid and Prodrugs …
Matched Products: … Taro-mycophenolate …

Bupropion

Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Matched Description: … commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and ... effects by weakly inhibiting the enzymes involved in the uptake of the neurotransmitters norepinephrine and ... from the synaptic cleft, therefore prolonging their duration of action within the neuronal synapse and …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … bupropion and naltrexone ... bupropion and dextromethorphan ... Dopamine And Norepinephrine Reuptake Inhibitors ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Taro-bupropion XL …

Anastrozole

Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such...
Approved
Investigational
Matched Description: … provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and ... drugs of choice in the treatment of postmenopausal breast cancer due to a more favourable efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Taro-anastrozole …

N-(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)-4-morpholin-4-yl-4-oxobutanamide

Experimental
Matched Name: … N-(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)-4-morpholin-4-yl-4-oxobutanamide …
Matched Iupac: … N-{4-bromo-2-[(3R,5S)-3,5-dimethylpiperidine-1-carbonyl]phenyl}-4-(morpholin-4-yl)-4-oxobutanamide …

Latanoprost

Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Description: … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse …
Matched Mixtures name: … Latanoprost and Timolol Ophthalmic Solution ... Latanoprost and Timolol STADA 50mcg/ml + 5mg/ml Eye drops ... LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPS …
Matched Categories: … Antiglaucoma Preparations and Miotics ... latanoprost and netarsudil …
Matched Products: … Taro-latanoprost …

Domperidone

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Taro-domperidone …

Sumatriptan

Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches ... [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available …
Matched Mixtures name: … Sumatriptan Succinate and Naproxen Sodium ... Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Genito Urinary System and Sex Hormones ... sumatriptan and naproxen ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Taro-sumatriptan …

Fenofibrate

Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Categories: … pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … Taro-fenofibrate E …

Apixaban

Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases[Label,A6897]. It is marketed under the name Eliquis[Label,L6043]. Apixaban was approved by the FDA on December 28,...
Approved
Matched Description: … Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa ... , as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Taro-apixaban …

1-(5-BROMO-PYRIDIN-2-YL)-3-[2-(6-FLUORO-2-HYDROXY-3-PROPIONYL-PHENYL)-CYCLOPROPYL]-UREA

Experimental
Matched Name: … 1-(5-BROMO-PYRIDIN-2-YL)-3-[2-(6-FLUORO-2-HYDROXY-3-PROPIONYL-PHENYL)-CYCLOPROPYL]-UREA …

5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide

Experimental
Matched Name: … 5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide …
Matched Iupac: … 5-bromo-N-{3-chloro-2-[4-(prop-2-yn-1-yl)piperazin-1-yl]phenyl}furan-2-carboxamide …

Granisetron

A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … TARAZ …

Sitagliptin

Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Description: … Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise ... The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon …
Matched Mixtures name: … Reddy-sitagliptin and Metformin Hydrochloride ... Reddy-sitagliptin and Metformin Hydrochloride ... Sitagliptin and metformin hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... sitagliptin and simvastatin ... metformin and sitagliptin ... sitagliptin and ertugliflozin ... sitagliptin and dapagliflozin …
Matched Products: … Taro-sitagliptin Fumarate …

Alpha-1-proteinase inhibitor

Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … Mucus proteinase inhibitor …
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …

Zoledronic acid

Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Description: … third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and ... [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia ... of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... zoledronic acid, calcium and colecalciferol, sequential …
Matched Products: … Taro-zoledronic Acid ... Taro-zoledronic Acid Concentrate …

Letrozole

Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Taro-letrozole …

8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide

Experimental
Matched Name: … 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole …
Matched Iupac: … 8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1H,2H,3H,6H-pyrrolo[3,4-e]indole-7-carboxamide …

Methylprednisolone

Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … Taro-methylprednisolone Injection …

Nifedipine

Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Description: … developed with slower onsets and longer durations of action. ... [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature ... [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... atenolol and nifedipine ... nifedipine and diuretics …
Matched Products: … Taro-nifedipine Cap 10mg …

Celecoxib

Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... [A181532] It is marketed by Pfizer under the brand name Celebrex, and was initially granted FDA approval ... selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antineoplastic and Immunomodulating Agents ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... tramadol and celecoxib ... amlodipine and celecoxib …
Matched Products: … Taro-celecoxib …

Doxorubicin

Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var ... [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Taro-doxorubicin Liposomal …

Pravastatin

Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Description: … It was the first statin administered as the active form and not as a prodrug. ... Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Matched Categories: … pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin and acetylsalicylic acid ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … Taro-pravastatin …

Lenalidomide

Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Description: … [A228708] However, lenalidomide is much safer and potent than thalidomide, with fewer adverse effects ... and toxicities. ... previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Taro-lenalidomide …
Displaying drugs 826 - 850 of 885 in total