Displaying drugs 76 - 100 of 16599 in total
Norepinephrine
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Synonyms: … (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol ... 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol ... (R)-noradrenaline …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Salts cas: … 108341-18-0 …
Matched Mixtures name: … XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUS …
Matched Categories: … Amino Alcohols ... Adrenergic beta-3 Receptor Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists …
Matched Products: … Levophed(r) Norepinephrine Bitartrate ... Norepinephrine Bitartrate In 5% Dextrose Injection ... Mykronor 5 Mikrogramm/ml Injektions-/Infusionslösung …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Salts cas: … 108341-18-0 …
Matched Mixtures name: … XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUS …
Matched Categories: … Amino Alcohols ... Adrenergic beta-3 Receptor Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists …
Matched Products: … Levophed(r) Norepinephrine Bitartrate ... Norepinephrine Bitartrate In 5% Dextrose Injection ... Mykronor 5 Mikrogramm/ml Injektions-/Infusionslösung …
Melphalan
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Synonyms: … 4-(Bis(2-chloroethyl)amino)-L-phenylalanine ... 3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine ... 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Salts cas: … 3223-07-2 …
Matched Categories: … Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Peptides, and Proteins …
Matched Products: … İÇEREN FLAKON+1 ADET ÇÖZÜCÜ İÇEREN FLAKON ... อัลเคอแรน (เม็ด 2 มก.) ... ALKERAN® 2 MG TABLETAS …
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Salts cas: … 3223-07-2 …
Matched Categories: … Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Peptides, and Proteins …
Matched Products: … İÇEREN FLAKON+1 ADET ÇÖZÜCÜ İÇEREN FLAKON ... อัลเคอแรน (เม็ด 2 มก.) ... ALKERAN® 2 MG TABLETAS …
Flurbiprofen
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Synonyms: … 3-fluoro-4-phenylhydratropic acid ... 2-(2-fluorobiphenyl-4-yl)propanoic acid ... (±)-2-fluoro-α-methyl-4-biphenylacetic acid …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic …
Matched Mixtures name: … MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 30 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 50 G …
Matched Categories: … Carboxylic Acids ... Arylpropionic acid NSAIDS ... Non COX-2 selective NSAIDS ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … MERDEX %5 TOPIKAL SPREY, ÇÖZELTİ 50 ML, 1 ŞIŞE ... SEMPTAL %5 TOPIKAL SPREY, ÇÖZELTİ, 50 ML, 1 ŞIŞE ... ZERO-P 100 MG FILM KAPLI TABLET, 30 ADET …
Matched Iupac: … 2-{2-fluoro-[1,1'-biphenyl]-4-yl}propanoic acid …
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic …
Matched Mixtures name: … MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 30 G ... MERDEX DUO %5 + %0.25 TOPIKAL JEL, 50 G …
Matched Categories: … Carboxylic Acids ... Arylpropionic acid NSAIDS ... Non COX-2 selective NSAIDS ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … MERDEX %5 TOPIKAL SPREY, ÇÖZELTİ 50 ML, 1 ŞIŞE ... SEMPTAL %5 TOPIKAL SPREY, ÇÖZELTİ, 50 ML, 1 ŞIŞE ... ZERO-P 100 MG FILM KAPLI TABLET, 30 ADET …
Lumiracoxib
Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zealand and Canada have also followed suit in recalling...
Approved
Investigational
Matched Synonyms: … 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid …
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid …
Matched Description: … Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). …
Matched Categories: … Carboxylic Acids ... COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates …
Matched Iupac: … 2-{2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid …
Matched Description: … Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). …
Matched Categories: … Carboxylic Acids ... COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates …
Bezafibrate
Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Approved
Investigational
Matched Synonyms: … 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid …
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Matched Categories: … Carboxylic Acids ... Fibric Acid Derivatives ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP3A Substrates …
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Matched Categories: … Carboxylic Acids ... Fibric Acid Derivatives ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Inhibitors ... Cytochrome P-450 CYP3A Substrates …
Methionine
A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Synonyms: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid ... (S)-2-amino-4-(methylthio)butanoic acid ... (S)-2-amino-4-(methylthio)butyric acid …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. …
Matched Salts cas: … 6810-12-4 …
Matched Mixtures name: … Amino Acid InJ.W.O.elect.5%dext. ... 4.25%travasol Amino Acid InJ.W.elecw.5%dex. ... 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex. …
Matched Categories: … Amino Acids ... Amino Acids, Neutral ... Amino Acids, Essential ... Amino Acids, Sulfur ... Proteinogenic Amino Acids …
Matched Iupac: … (2S)-2-amino-4-(methylsulfanyl)butanoic acid …
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. …
Matched Salts cas: … 6810-12-4 …
Matched Mixtures name: … Amino Acid InJ.W.O.elect.5%dext. ... 4.25%travasol Amino Acid InJ.W.elecw.5%dex. ... 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex. …
Matched Categories: … Amino Acids ... Amino Acids, Neutral ... Amino Acids, Essential ... Amino Acids, Sulfur ... Proteinogenic Amino Acids …
Naproxen
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched International brands: … Proxen S …
Matched Synonyms: … (S)-2-(6-Methoxy-2-naphthyl)propanoic acid ... (S)-2-(6-Methoxy-2-naphthyl)propionic acid ... (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid …
Matched Iupac: … (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid …
Matched Salts cas: … 26159-34-2 …
Matched Mixtures name: … PENSODIL-S ... VELSAY-S COMPUESTO ... NAPROSYN PLUS %10+% 5 JEL,30G …
Matched Categories: … Arylpropionic acid NSAIDS ... Non COX-2 selective NSAIDS ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates …
Matched Products: … 7 Select Naproxen Sodium ... ALEVE (R) TABLETAS 220 MG ... NAPROXENO 3 % …
Matched Synonyms: … (S)-2-(6-Methoxy-2-naphthyl)propanoic acid ... (S)-2-(6-Methoxy-2-naphthyl)propionic acid ... (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid …
Matched Iupac: … (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid …
Matched Salts cas: … 26159-34-2 …
Matched Mixtures name: … PENSODIL-S ... VELSAY-S COMPUESTO ... NAPROSYN PLUS %10+% 5 JEL,30G …
Matched Categories: … Arylpropionic acid NSAIDS ... Non COX-2 selective NSAIDS ... P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates …
Matched Products: … 7 Select Naproxen Sodium ... ALEVE (R) TABLETAS 220 MG ... NAPROXENO 3 % …
Chloroprocaine
Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Synonyms: … 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester ... 2-(Diethylamino)ethyl 4-amino-2-chlorobenzoate ... 2-chloroprocaine …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-2-chlorobenzoate …
Matched Salts cas: … 3858-89-7 …
Matched Categories: … Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Products: … Nesacaine Ce 2% Inj 20mg/ml ... Nesacaine Ce 3% Inj 30mg/ml …
Matched Iupac: … 2-(diethylamino)ethyl 4-amino-2-chlorobenzoate …
Matched Salts cas: … 3858-89-7 …
Matched Categories: … Carboxylic Acids ... Esters of Aminobenzoic Acid …
Matched Products: … Nesacaine Ce 2% Inj 20mg/ml ... Nesacaine Ce 3% Inj 30mg/ml …
Metolazone
A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Synonyms: … 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide ... 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide ... 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone …
Matched Iupac: … 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Oseltamivir
Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Synonyms: … 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha ... Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate …
Matched Iupac: … ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate …
Matched Description: … oseltamivir in people with a higher risk of developing complications including children younger than 2 ... non-specific effects on symptoms (where the time to first alleviation of symptoms was only reduced from 7 …
Matched Products: … TAZAMIR(R) CAPSULA 75 MG ... FLUHALT FOR ORAL SUSPENSION 60 mg/ 5 ml …
Matched Iupac: … ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate …
Matched Description: … oseltamivir in people with a higher risk of developing complications including children younger than 2 ... non-specific effects on symptoms (where the time to first alleviation of symptoms was only reduced from 7 …
Matched Products: … TAZAMIR(R) CAPSULA 75 MG ... FLUHALT FOR ORAL SUSPENSION 60 mg/ 5 ml …
Aceclofenac
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid carboxymethyl ester …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Mixtures name: … ZERODOL P …
Matched Categories: … Carboxylic Acids ... Acetic Acid Derivatives and Related Substances ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Mixtures name: … ZERODOL P …
Matched Categories: … Carboxylic Acids ... Acetic Acid Derivatives and Related Substances ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Febuxostat
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Synonyms: … 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid …
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid …
Matched Description: … , thereby reducing serum uric acid levels. ... [L32238] Gout is a form of arthritis that is caused by the accumulation of uric acid crystal in or around ... a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones, joints …
Matched Salts cas: … 442664-09-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Preparations Inhibiting Uric Acid Production ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid …
Matched Description: … , thereby reducing serum uric acid levels. ... [L32238] Gout is a form of arthritis that is caused by the accumulation of uric acid crystal in or around ... a joint, leading to inflammation and further deposition of uric acid crystal deposition in bones, joints …
Matched Salts cas: … 442664-09-7 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Preparations Inhibiting Uric Acid Production ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C8 Substrates …
Cinoxacin
Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid ... 5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
Matched Iupac: … 1-ethyl-4-oxo-1H,4H,7H-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid …
Matched Description: … Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) …
Ioxaglic acid
Ioxaglic acid is marketed as Hexabrix. This drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during...
Approved
Investigational
Matched Synonyms: … Ioxaglic acid …
Matched Name: … Ioxaglic acid …
Matched Iupac: … 3-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodo-5-(2-{[2,4,6-triiodo-3-(methylcarbamoyl)-5-(N-methylacetamido ... )phenyl]formamido}acetamido)benzoic acid …
Matched Description: … Ioxaglic acid is marketed as Hexabrix. ... Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast …
Matched Salts cas: … 59018-13-2 …
Matched Categories: … Carboxylic Acids ... ioxaglic acid …
Matched Name: … Ioxaglic acid …
Matched Iupac: … 3-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodo-5-(2-{[2,4,6-triiodo-3-(methylcarbamoyl)-5-(N-methylacetamido ... )phenyl]formamido}acetamido)benzoic acid …
Matched Description: … Ioxaglic acid is marketed as Hexabrix. ... Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray ... Ioxaglic acid has a low osmolarity and is associated with fewer side effects compared to older contrast …
Matched Salts cas: … 59018-13-2 …
Matched Categories: … Carboxylic Acids ... ioxaglic acid …
Ezogabine
Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Synonyms: … Ethyl 2-amino-4-((p-fluorobenzyl)amino)carbanilate ... N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester ... N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 …
Matched Categories: … Carboxylic Acids …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 …
Matched Categories: … Carboxylic Acids …
Clofarabine
Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic...
Approved
Investigational
Matched Synonyms: … (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol ... 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine ... 2-chloro-9-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)adenine …
Matched Iupac: … (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … FARABIN 1 MG/ ML SOLUCIÓNINYECTABLE ... CLOLAR 1 MG/ML SOLUCION CONCENTRADA PARA INFUSION ... CLOLAR® 1 MG/ML SOLUCION CONCENTRADA PARA INFUSION …
Matched Iupac: … (2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … FARABIN 1 MG/ ML SOLUCIÓNINYECTABLE ... CLOLAR 1 MG/ML SOLUCION CONCENTRADA PARA INFUSION ... CLOLAR® 1 MG/ML SOLUCION CONCENTRADA PARA INFUSION …
Metrizoic acid
Metrizoic acid is a molecule used as a contrast medium. It present a higher risk of allergic reactions due to its high osmolality. Its approval has been discontinued by the FDA. One study in 1976 demonstrated that metrizoic acid, when used for cardiac angiography, was well tolerated. A total of...
Approved
Matched Synonyms: … Metrizoic acid …
Matched Name: … Metrizoic acid …
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzoic acid …
Matched Description: … Seven cases of ventricular fibrillation, and 5 of significant bradycardia/asystole, were associated with ... metrizoic acid injection. ... Metrizoic acid is a molecule used as a contrast medium. …
Matched Salts cas: … 7241-11-4 ... 20828-80-2 ... 20968-37-0 …
Matched Categories: … Carboxylic Acids ... metrizoic acid …
Matched Name: … Metrizoic acid …
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(N-methylacetamido)benzoic acid …
Matched Description: … Seven cases of ventricular fibrillation, and 5 of significant bradycardia/asystole, were associated with ... metrizoic acid injection. ... Metrizoic acid is a molecule used as a contrast medium. …
Matched Salts cas: … 7241-11-4 ... 20828-80-2 ... 20968-37-0 …
Matched Categories: … Carboxylic Acids ... metrizoic acid …
Gluconic Acid
Commonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Approved
Investigational
Matched Synonyms: … Maltonic acid ... Dextronic acid ... D-Gluconic Acid …
Matched Name: … Gluconic Acid …
Matched Iupac: … (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid …
Matched Description: … Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions. …
Matched Salts cas: … 527-07-1 …
Matched Mixtures name: … Normosol-R & 5% Dextrose ... Isolyte S With 5% Dextrose Inj ... MULTIELECTROLITOS TIPO 1 …
Matched Categories: … Carboxylic Acids …
Matched Name: … Gluconic Acid …
Matched Iupac: … (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid …
Matched Description: … Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions. …
Matched Salts cas: … 527-07-1 …
Matched Mixtures name: … Normosol-R & 5% Dextrose ... Isolyte S With 5% Dextrose Inj ... MULTIELECTROLITOS TIPO 1 …
Matched Categories: … Carboxylic Acids …
Carprofen
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years (1985-1995). It was generally well tolerated, with the majority of adverse effects being mild,...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid ... 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid ... (±)-6-chloro-α-methylcarbazole-2-acetic acid …
Matched Iupac: … 2-(6-chloro-9H-carbazol-2-yl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Heterocyclic Compounds, 2-Ring ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Matched Iupac: … 2-(6-chloro-9H-carbazol-2-yl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Heterocyclic Compounds, 2-Ring ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) …
Eprosartan
Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Synonyms: … (E)-3-[2-n-butyl-1-{(4-carboxyphenyl)methyl}-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid ... (E)-2-butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid ... (E)-α{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid …
Matched Iupac: … 4-({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic ... acid …
Matched Description: … It performs 2 actions on the renin angiotensin system. …
Matched Salts cas: … 144143-96-4 ... 197855-71-3 …
Matched Categories: … Carboxylic Acids ... Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 1-Ring ... Angiotensin II Type 1 Receptor Blockers …
Matched Iupac: … 4-({2-butyl-5-[(1E)-2-carboxy-2-[(thiophen-2-yl)methyl]eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic ... acid …
Matched Description: … It performs 2 actions on the renin angiotensin system. …
Matched Salts cas: … 144143-96-4 ... 197855-71-3 …
Matched Categories: … Carboxylic Acids ... Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 1-Ring ... Angiotensin II Type 1 Receptor Blockers …
Bempedoic acid
High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. Caused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are...
Approved
Investigational
Matched Synonyms: … Bempedoic acid …
Matched Name: … Bempedoic acid …
Matched Iupac: … 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid …
Matched Description: … [L12153] About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are insufficiently managed ... [L12180] Bempedoic acid is first-in-class adenosine triphosphate-citrate lyase (ACL) inhibitor used ... A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased …
Matched Categories: … Carboxylic Acids ... bempedoic acid ... bempedoic acid and ezetimibe …
Matched Name: … Bempedoic acid …
Matched Iupac: … 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid …
Matched Description: … [L12153] About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are insufficiently managed ... [L12180] Bempedoic acid is first-in-class adenosine triphosphate-citrate lyase (ACL) inhibitor used ... A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased …
Matched Categories: … Carboxylic Acids ... bempedoic acid ... bempedoic acid and ezetimibe …
Thiosulfuric acid
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Synonyms: … Sulfurothioic S-acid ... Monosulfanemonosulfonic acid …
Matched Name: … Thiosulfuric acid …
Matched Iupac: … dihydroxy-1lambda6-disulfen-1-one …
Matched Description: … [L43337] When administered 6 hours after cisplatin chemotherapy, Sodium thiosulfate leads to a lower ... Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid …
Matched Salts cas: … 7772-98-7 ... 10102-17-7 …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Sodium Polysulthionate, 5-mthf …
Matched Categories: … Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2B6 Inducers (strength unknown) …
Matched Name: … Thiosulfuric acid …
Matched Iupac: … dihydroxy-1lambda6-disulfen-1-one …
Matched Description: … [L43337] When administered 6 hours after cisplatin chemotherapy, Sodium thiosulfate leads to a lower ... Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... L43332,A252832] and it is frequently used in conjunction with sodium nitrite (a salt form of [nitrous acid …
Matched Salts cas: … 7772-98-7 ... 10102-17-7 …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... Sodium Polysulthionate, 5-mthf …
Matched Categories: … Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2B6 Inducers (strength unknown) …
Meclofenamic acid
A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Approved
Vet approved
Matched Synonyms: … N-(2,6-dichloro-3-methylphenyl)anthranilic acid ... N-(3-methyl-2,6-dichlorophenyl)anthranilic acid ... Meclofenamic acid …
Matched Name: … Meclofenamic acid …
Matched Iupac: … 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid …
Matched Salts cas: … 67254-91-5 …
Matched Categories: … Carboxylic Acids ... Non COX-2 selective NSAIDS ... meclofenamic acid ... meclofenamic acid …
Matched Name: … Meclofenamic acid …
Matched Iupac: … 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid …
Matched Salts cas: … 67254-91-5 …
Matched Categories: … Carboxylic Acids ... Non COX-2 selective NSAIDS ... meclofenamic acid ... meclofenamic acid …
Sofosbuvir
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 ... -methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … Approved in October 2014 by the FDA, Harvoni is indicated for the treatment of HCV genotypes 1, 4, 5, ... -deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective ... and 6 with or without [DB00811] depending on the level of liver damage or cirrhosis [FDA Label]. …
Matched Categories: … P-glycoprotein substrates ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … Approved in October 2014 by the FDA, Harvoni is indicated for the treatment of HCV genotypes 1, 4, 5, ... -deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective ... and 6 with or without [DB00811] depending on the level of liver damage or cirrhosis [FDA Label]. …
Matched Categories: … P-glycoprotein substrates ... Heterocyclic Compounds, 1-Ring …
Nabumetone
Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Synonyms: … 4-(6-Methoxy-2-naphthyl)-2-butanone ... 4-(6-Methoxy-2-naphthalenyl)-2-butanone …
Matched Iupac: … 4-(6-methoxynaphthalen-2-yl)butan-2-one …
Matched Description: … [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite ... [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … DOLORSIN 1 G …
Matched Iupac: … 4-(6-methoxynaphthalen-2-yl)butan-2-one …
Matched Description: … [label,A178903] The molecule itself is a pro-drug with its 6-methoxy-2-naphthylacetic acid (6-MNA) metabolite ... [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone …
Matched Categories: … COX-2 Inhibitors ... Selective Cyclooxygenase 2 Inhibitors (NSAIDs) ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2C9 Substrates …
Matched Products: … DOLORSIN 1 G …
Displaying drugs 76 - 100 of 16599 in total