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Displaying drugs 76 - 100 of 5172 in total
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … and matured by TLR3 ligand _ex vivo_. ... It is under investigation for the treatment of ovarian cancer. ... DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells …
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … ), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic ... CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Phosphatidic Acids
Nutraceutical
Matched Mixtures name: … frida mom Labor and Delivery Plus Postpartum Recovery ... frida mom Labor and Delivery Plus Postpartum Recovery ... Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) …
Matched Categories: … Astringents and Deodorants ... Herbs and Natural Products ... Skin and Mucous Membrane Agents …
Matched Products: … Distilled Witch Hazel Liq 100% ... Jw Tonic II ... Collagen Plus Daily Mask …
Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Synonyms: … Tin(II) fluoride …
Matched Description: … Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient ... It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing ... in toothpastes, stannous fluoride has been shown to be more effective at stopping and reversing dental …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism ... Compounds used in a research, industrial, or household setting …
Matched Products: … Up and Up Anticavity Toothpaste Multi Function ... Sensodyne Sensitivity and Gum Clean and Fresh ... Crest Sensi-Repair and Prevent …
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally ... acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NOVOEİGHT 250 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... NOVOEİGHT 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... NOVOEİGHT 1000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Experimental
Matched Synonyms: … Hypochlorous acid, calcium salt …
Matched Mixtures name: … INFECCO Eusol (Solution A AND B) Antiseptic …
Matched Products: … Eusol I and II
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Iupac: … 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... This drug was the first clinical useful drug in its class, and its approval was followed by the formulation ... acid-related disorders. …
Matched Mixtures name: … ORAZOLE ® 10 MG CAPSULA ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Salts name: … Omeprazole sodium
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism …
Matched Products: … Omeprazol Biosan 10 mg - Kapseln ... Up and Up Omeprazole ... Berkley and Jensen Omeprazole …
Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... It is shown to be effective in mediating its antimicrobial action against bacteria, fungi, mold and viruses ... Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum …
Matched Salts cas: … 121-54-0 …
Matched Mixtures name: … Salicylic Acid ... I.C. Barrier ... Aspiera Wound Care and Antiseptic …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … Charm Tex 3 IN 1 Antibacterial Shave Gel Body Wash ... 3 in 1 First Aid Wound Care ... Alpha Foaming E-2 …
Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Synonyms: … Selenium(IV) sulfide ... Selenium(IV) sulphide ... Selenium(IV) disulfide …
Matched Description: … dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent children ... cells in seborrhea. ... Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Selsun Blue 2-in-1 ... Selsun Blue, 2-IN-1 ... SESUL SÜSPANSİYON, 120 ML …
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … FDA in 1951 and is available in a variety of forms including syrup form, regular tablets, effervescent ... of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines ... and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). …
Matched Mixtures name: … Acetaminophen, Ascorbic acid, Chlorpheniramine Maleate ... ALPARA ... ALPARA
Matched Categories: … Acetaminophen and Prodrugs ... codeine and paracetamol ... tramadol and paracetamol ... oxycodone and paracetamol ... dihydrocodeine and paracetamol …
Matched Products: … PROLIEF ... PROLIEF BLUE ... PROLIEF ORANGE …
Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). IgE promotes the release of inflammatory mediators from mast cells and basophils during allergic and inflammatory reactions. By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its...
Approved
Investigational
Matched Description: … By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding ... [A39518] Omalizumab was first approved in the US in 2003 [A263507] and in Europe in 2005. ... [L50482] It is used to treat a range of immune and inflammatory conditions, including allergies, urticaria …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Anti-IgE ... Decreased IgE Activity ... IgE-directed Antibody Interactions …
Matched Products: … Xolair 75mg Powder and Solvent for Solution for Injection ... XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... Xolair 150mg Powder and Solvent for Solution for Injection …
Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Compounds used in a research, industrial, or household setting …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Iupac: … (4S)-N-{4-[(2S)-2-{[(1R)-2-[4-(carbamoylamino)phenyl]-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1R)-1-carbamoylethyl ... ]carbamoyl}pyrrolidin-1-yl]-1-oxo-6-[(propan-2-yl)amino]hexan-2-yl]carbamoyl}-3-methylbutyl]carbamoyl ... )propanamido]propanamido]-3-(pyridin-3-yl)propanamido]-3-hydroxypropanamido]ethyl]phenyl}-2,6-dioxo-1,3
Matched Description: … receptors in the pituitary gland and blocks interaction with GnRH. ... Chemically, it is a synthetic linear decapeptide amide with seven unnatural amino acids, five of which ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately …
Matched Salts cas: … 934246-14-7 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … FIRMAGON Powder and Solvent for Solution for Injection 120 mg ... เฟอร์มากอน 120 มก. ... Firmagon 120mg Powder and Solvent for Solution for Injection …
Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … ], which is produced by recombinant DNA technology and is identical in sequence to endogenously produced ... Exogenous replacement of Factor VIII is currently the cornerstone of Hemophilia treatment and is used ... Antihemophilic factor human is approved by the Food and Drug Administration for use in hemophilia A ( …
Matched Mixtures name: … Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection ... Haemate P Powder and solvent for solution for injection or infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250 IU ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in ... It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... It is a structurally-related compound to [DB02362] that absorbs UV-B rays to prevent photodamage. …
Matched Mixtures name: … Sun and Ski Stick SPF 15 ... Skin Pro-tec II SPF-15 ... Ice Lipbalm SPF 12- Stk Top …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Compounds used in a research, industrial, or household setting …
Matched Products: … Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 ... Chap-ice SPF 4 Cherry Lip Balm …
Investigational
Matched Synonyms: … surface receptor and cd3 ... Bispecific t-cell engager antibody with a single chain fc moiety that binds to b cell maturation antigen …
Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Iupac: … dialuminium(3+) ion hydrate chloride pentahydroxide …
Matched Description: … It is also used as a coagulant in the water purification process. ... It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. ... is relatively near the skin surface [A27159]. …
Matched Mixtures name: … KURSEPT %19 + %1 KREM (30 G) ... PERS-MANT %19 + %2 JEL (30 G) …
Matched Categories: … Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Gillette Arctic Ice Invisible ... Charm-Tex Deodorant ... Charm-Tex ANTIPERSPIRANT ROLL-ON DEODORANT …
Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Synonyms: … Coagulation factor IX (recombinant), albumin fusion protein ... Coagulation Factor IX (Recombinant), Albumin Fusion Protein (rIX-FP) …
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …
Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... A to manage and prevent bleeding episodes. ... It was first approved by the European Commission in January 2018. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Synonyms: … Heparinic acid
Matched Description: … and higher risk of osteoporosis in long term use. ... coagulation enzymes thrombin (factor IIa) and factor Xa. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj ... Heparin Sodium in Dextrose …
Matched Salts name: … Heparin sodium
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Matched Products: … Heparin Sodium and Sodium Chloride ... Heparin Sodium and Dextrose ... HEPARINOL 10000 IU/mL (Heparin Sodium (Bovine) Injection BP 10000 IU/mL) …
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Synonyms: … (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid ... (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid ... Zoledronic acid
Matched Name: … Zoledronic acid
Matched Iupac: … [1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid
Matched Description: … [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia ... to [ibandronic acid], [minodronic acid], and [risedronic acid]. ... [L13712,L13715,L13721] Zoledronic acid was first described in the literature in 1994. …
Matched Salts name: … Zoledronic acid monohydrate ... Zoledronic acid hemipentahydrate …
Matched Categories: … zoledronic acid, calcium and colecalciferol, sequential ... Drugs Affecting Bone Structure and Mineralization ... Heterocyclic Compounds, 1-Ring ... zoledronic acid
Matched Products: … ZOMETA 4 MG/100 ML INF LSG ... ZOLCURE 5 MG/100 ML I.V. İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... VERTEBZOL 5 MG/100 ML I.V. İNFÜZYONLUK ÇÖZELTİ, 100 ML …
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. ... -TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE …
Matched Iupac: … (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy ... -3-phenylpropanoyl]oxy}-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0 ... ^{3,10}.0^{4,7}]heptadec-13-en-2-yl benzoate …
Matched Description: … [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 ... It was first approved by the FDA on June 17, 2010. ... A260621] As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION ... Cabazred 60mg/1.5ml Concentrate And Solvent For Solution For Infusion ... JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION) …
Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Synonyms: … Ibandronic acid
Matched Iupac: … {1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl}phosphonic acid
Matched Description: … acid], [minodronic acid], and [risedronic acid]. ... [A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis. ... [A203138] Ibandronate was granted FDA approval on 16 May 2003.[L13805] …
Matched Salts cas: … 138926-19-9 …
Matched Mixtures name: … IBAMIN D3 150 MG/2800 IU SAŞE ,3 SAŞE ... IBAMIN D3 150 MG/2800 IU FİLM KAPLI TABLET, 3 ADET …
Matched Salts name: … Ibandronate sodium
Matched Categories: … ibandronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization ... ibandronic acid
Matched Products: … Ibandronate Sodium ... Ibandronate sodium ... IBANDRONIC ACID ACC3MG ILO
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
Displaying drugs 76 - 100 of 5172 in total