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Displaying drugs 101 - 125 of 3968 in total
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Superagonist interleukin-15:interleukin-15 receptor alphasu/fc fusion complex alt-803 ... Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) ... Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … [A263617, A263622] Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , ... stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and
Matched Categories: … Receptors, Interleukin-15 ... Amino Acids, Peptides, and Proteins …
Investigational
Matched International brands: … Sporidin-G
Matched Synonyms: … Bovine anti-cryptosporidium hyperimmune colostrum immunoglobulin ... Bovine hyperimmune anti-Cryptosporidium colostrum immunoglobulin ... Bovine immunoglobulin concentrate, cryptosporidium parvum …
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … (1'R,2R,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)- ... }]pentacosane]-10',14',16',22'-tetraen-2'-one; (1'R,2R,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21 ... [oxane-2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one ... -6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-3',7',19'-trioxaspiro ... 5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13
Matched Description: … (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro ... use for the prophylaxis and treatment of COVID-19. ... With the advent of 2020 and the COVID-19 pandemic, ivermectin began garnering notoriety due to its off-label …
Matched Mixtures name: … Ivermectin 1% / Metronidazole 1% ... Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... 171083 Ivermectin 1% / Metronidazole 1% / Niacinamide 4% …
Matched Categories: … Anti-Infective Agents ... Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... SOOLANTRA 10 MG/G KREM, 30 G ... Soolantra 10 mg/g Creme …
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Synonyms: … -thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo ... (6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5 …
Matched Iupac: … -thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5 …
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Mixtures name: … SEFOTAK 1 G IM ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADET …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …
Matched Products: … Cefotaxime and Dextrose ... CEFOTAXIMA 1 G ... CLAFORAN 2.0 G TOZ+10 CC ÇÖZÜCÜ AMPUL, 1 ADET …
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against both compared to third-generation antibiotics.[A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused by multi-resistant microorganisms such as Pseudomonas aeruginosa, and is also indicated...
Approved
Investigational
Matched Synonyms: … -1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ... (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(1-methylpyrrolidinium …
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methylpyrrolidin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-carboxylato-8-oxo-5-thia …
Matched Description: … Cefepime is active against Gram-positive and Gram-negative bacteria, and has greater activity against ... [A2457,A249050] Cefepime is normally used to treat severe nosocomial pneumonia and infections caused ... by multi-resistant microorganisms such as _Pseudomonas aeruginosa_, and is also indicated for the empirical …
Matched Categories: … cefepime and amikacin ... Anti-Bacterial Agents ... Anti-Infective Agents …
Matched Products: … Cefepime Hydrochloride and Dextrose ... CEFEPIMA 1 G ... CEFEPEN INJECTION 1 g
Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system. Although the indazole analogue benzydamine is a...
Approved
Matched Iupac: … {3-[(1-benzyl-1H-indazol-3-yl)oxy]propyl}dimethylamine …
Matched Description: … It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal ... drug (NSAID) with local anaesthetic and analgesic properties. ... Although the indazole analogue benzydamine is a non-steroidal anti-inflammatory drug (NSAID), it has …
Matched Salts cas: … 132-69-4 …
Matched Mixtures name: … Anti-inflammatory Lozenge (with antibacterial) (Eucalyptus and Menthol) ... Difflam mouth gel ... DIFFLAM MOUTH GEL
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Anti-Inflammatory Agents ... Anti-Inflammatory Agents, Non-Steroidal ... Mouthwashes and Gargles ... Alimentary Tract and Metabolism …
Matched Products: … TANTUM %5 JEL, 100 G ... Anti-Inflammatory Throat Spray ... Difflam Anti-Inflammatory 3mg Lozenges …
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(rabies lyssavirus spike glycoprotein g) (human-mus musculus clone 2g11 .gamma ... .1-chain), disulfide with human-mus musculus clone 2g11 .kappa. …
Lumiliximab is a chimeric monoclonal antibody which is used as an immunosuppressive drug. It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE antibody, for the potential treatment of allergic conditions. Lumiliximab was developed by IDEC Pharmaceuticals, which was acquired by Biogen. Clinical trials for...
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC- ... IMMUNOGLOBULIN G1, ANTI-(HUMAN IMMUNOGLOBULIN E RECEPTOR TYPE II) (HUMAN-MACACA IRUS MONOCLONAL IDEC- ... PRIMATIZED ANTI-CD23 …
Matched Description: … Clinical trials for CLL were terminated in 2010, and for allergic asthma in 2007. ... It is a primatized anti-CD23 macaque/human chimeric antibody that inhibits the production of the IgE …
Matched Categories: … Immunoglobulins ... Amino Acids, Peptides, and Proteins …
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Synonyms: … (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7- ... oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Iupac: … (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl ... -7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam ... Anti-Bacterial Agents ... Anti-Infective Agents …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP ... MEROPENEM 1 G
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Matched Synonyms: … Immunoglobulin g (234-proline,303-glutamine), anti-(human oncostatin m receptor subunit .beta.) …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and
Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein linked to the Fc portion of immunoglobulin G1. Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome...
Approved
Investigational
Matched Synonyms: … interleukin-1 (IL-1) trap ... IL-1 TRAP ... IL-1-TRAP …
Matched Description: … linked to the Fc portion of immunoglobulin G1. ... Rilonacept functions as an interleukin 1 inhibitor and is used in the treatment of CAPS, also known as ... Rilonacept is a dimeric fusion protein consisting of portions of IL-1R and the IL-1R accessory protein …
Matched Categories: … Interleukin-1 Blockers ... Receptors, Interleukin-1 Type I ... Anti-Inflammatory Agents ... Interleukin-1 Receptor Accessory Protein ... Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … -tetra-l-lysine)human interleukin 8 precursor-(34-99)- peptide anti-inflammatory ... Interleukin 8 (synthetic human clone dncxcl8 increased-glycosaminoglycan binding isoform pa401) ... Recombinant dna derived, human interleukin 8 (cxcl8) mutein, produced in escherichia coli: (44,48,97,98 …
Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Synonyms: … human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA …
Investigational
Matched Synonyms: … 75-133-interleukin 2 (125-serine) (human) fusion protein with peptide linker (gg) fusion protein with ... 75-133-Interleukin 2 [125-serine] (human) fusion protein with peptide linker (GG) fusion protein with ... 2 receptor .alpha. …
INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being investigated to treat Shiga-toxin producing bacterial infection relating to the prevention of hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Anti-Shiga toxin hyperimmune equine immunoglobulin F(ab')2 fragment ... Neutralizing equine anti-Stx hyperimmune immunoglobulin F(ab')2 fragment …
Matched Description: … INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being …
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Iupac: … 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine …
Matched Description: … preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. ... Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular …
Matched Mixtures name: … SİMBRİNZA 10 MG/ML + 2 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 5 ML ... Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... RIMOSOPT GÖZ DAMLASI, 5 ML …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents ... Antiglaucoma Preparations and Miotics …
Matched Products: … BREMON %0.2 GÖZ DAMLASI,5 ML, 1 ŞIŞE ... BREMON %0,1 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... BRİOP % 0.15 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … Alpha 1-antitrypsin ... Alpha-1-antitrypsin ... .Alpha.-1 protease inhibitor …
Matched Name: … Alpha-1-proteinase inhibitor …
Matched Description: … Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol ... fractionation followed by PEG and zinc chloride fractionation. …
Matched Categories: … Human alpha-1 Proteinase Inhibitor ... Alpha-Globulins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Alpha1-proteinase Inhibitor (human) ... PROLASTIN C 1000 MG IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … , in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions [A32213]. ... Allantoin is a substance that is endogenous to the human body and also found as a normal component of ... During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated …
Matched Mixtures name: … NOSKAR 100 MG/50 IU/10 MG / G, JEL 120 G ... NOSKAR 100 MG/50 IU/10 MG / G, JEL 100 G ... NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 G
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Herbs and Natural Products ... Basic Ointments and Protectants …
Matched Products: … Miracle GYN (10 Tablets) ... Anti Chafe Balm ... Bodyglide anti chafe balm …
Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Description: … During in vitro testing to demonstrate anti-bacterial activity it was found that the complex was less ... Shelanski and M. V. Shelanski. ... Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine …
Matched Mixtures name: … Loris 10% Povidone-Iodine and 70% Isopropyl Alcohol Solution ... Mlp A-1 ... GFA First Aid 36 Unit Metal Case …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Anti-Infective Agents ... Anti-Infective Agents, Local ... Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones …
Matched Products: … Alpha One ... BETADINE FEMININE DOUCHE and WASH 10% w/v ... BIO-BACTEDENE GEL 10%W/W …
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Iupac: … (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-1-(2-chloroacetyl)-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H, ... 2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl furan-2-carboxylate …
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Mixtures name: … FUNIDE PLUS GEL ... ELOSALIC MERHEM, 30 G ... ELOSALIC MERHEM, 45 G
Matched Categories: … formoterol and mometasone ... Anti-Allergic Agents ... Anti-Inflammatory Agents …
Matched Products: … Up and Up Allergy ... Nasonex Allergy and Congestion ... Nasal Allergy and Congestion Relief …
Investigational
Matched Name: … Leukocyte interleukin
Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders. Pramocaine is available by itself and in combination with other medications...
Approved
Matched Description: … Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. ... bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders ... It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect …
Matched Salts cas: … 637-58-1
Matched Mixtures name: … HIPOKORT ARTI %2,5 + %1 LOSYON 50 GR ... HİPOKORT ARTI %2,5 + %1 DERİ KÖPÜĞÜ, 50 G ... Johnson and Johnson First Aid All Purpose 160 CT …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Anti Itch Soothing 1 Pramoxine Hydrochloride ... Anti-Itch Soothing Wipes 1 Pramoxine Hydrochloride ... Tronothane Pramoxine HCl Crm 1% USP …
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... activity targeting her2 and her3 receptors.) ... clone mcla-128 .gamma.1-chain), disulfide with humanized clone mcla-128 light chain, dimer …
Matched Description: … in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immunoglobulins ... Immunoglobulin Isotypes …
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. It is one of the active ingredients in Anktiva, a combination product also containing nogapendekin alfa, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA...
Investigational
Matched Synonyms: … INTERLEUKIN 15 RECEPTOR .ALPHA. ... INTERLEUKIN 15 RECEPTOR SUBUNIT ALPHA (HUMAN IL15R.ALPHA.) (1-65)-PEPTIDE (SUSHI DOMAIN-CONTAINING) FUSION ... CHAIN (HUMAN SUSHI DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT …
Matched Description: … the activation and proliferation of natural killer cells and CD8+ memory T cells, which also synergistically ... Inbakicept is a dimeric human IL-15 receptor α (IL-15Rα) sushi domain/human IgG1 Fc fusion protein. ... [A263617, A263622] Inbakicept, in combination with nogapendekin alfa, mimics the actions of IL-15, stimulating …
Matched Categories: … Interleukin-15 ... Receptors, Interleukin-15 ... Amino Acids, Peptides, and Proteins ... Experimental Unapproved Treatments for COVID-19
Displaying drugs 101 - 125 of 3968 in total