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Displaying drugs 1326 - 1350 of 1392 in total

Methapyrilene

Methapyrilene, formerly marketed in many drug products, was shown to be a potent carcinogen. Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979.
Withdrawn
Matched Synonyms: … 2-[[2-(Dimethylamino)ethyl]-2-thenylamino]pyridine …
Matched Description: … Manufacturers voluntarily withdrew methapyriline drug products from the market in May and June 1979. …
Matched Salts name: … Methapyrilene hydrochloride …
Matched Categories: … Hypnotics and Sedatives …

MPT-0L055

Investigational
Matched Synonyms: … 4-(((3-chloro-1,4-dioxo-1,4 dihydronaphthalen-2-yl)amino)methyl)-n-(pyridine-3-yl)benzamide …

AVA-6000

Investigational
Matched Synonyms: … dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl]oxy}oxan-4-yl)carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]pyridine …

Ambroxol

Ambroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the...
Approved
Investigational
Matched Description: … It stimulates synthesis and release of surfactant by type II pneumocytes. ... in providing protection against infection and irritating agents. ... The substance is a mucoactive drug with several properties including secretolytic and secretomotoric …
Matched Salts name: … Ambroxol hydrochloride …
Matched Categories: … Cough and Cold Preparations ... clenbuterol and ambroxol …
Matched Products: … AMBROXOL HYDROCHLORIDE ... ZERINOL GOLA MENTA …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and ... -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). ... A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Daptomycin in Sodium Chloride …

Trazodone

Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Description: … Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors ... [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as ... tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine …
Matched Salts name: … Trazodone hydrochloride …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Trazodone Hydrochloride …

Magrolimab

Magrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Investigational
Matched Synonyms: … .4-chain), disulfide with human-mus musculus monoclonal hu5f9-g4 .kappa. ... Immunoglobulin g4(225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal hu5f9-g4 .gamma …
Matched Description: … NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Nadide

A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Experimental
Matched Synonyms: … Pyridine, nucleotide diphosphate …
Matched Description: … electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …

2-amino-7-fluoro-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide

Experimental
Matched Name: … 2-amino-7-fluoro-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide …
Matched Iupac: … 2-amino-7-fluoro-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxamide …

Apomorphine

Apomorphine is a non-ergoline dopamine D2 agonist indicated to treat hypomobility associated with Parkinson's. It was first synthesized in 1845 and first used in Parkinson's disease in 1884. Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.[A203597,A203618] Apomorphine...
Approved
Investigational
Matched Description: … It was first synthesized in 1845 and first used in Parkinson's disease in 1884. ... A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and …
Matched Salts name: … Apomorphine hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Apomorphine Hydrocloride …

3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine

Experimental
Matched Name: … 3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine …

4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE

Experimental
Matched Name: … 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE …
Matched Iupac: … 4-[5-(3-iodophenyl)-2-{4-[(R)-methanesulfinyl]phenyl}-1H-imidazol-4-yl]pyridine …

Metronidazole

Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Description: … , and amebiasis which are parasitic infections. ... It is available in capsule form, tablet form, and topical form, and suppository preparations for the ... [L3754] It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride ... Bismuth Subsalicylate/Metronidazole/Tetracycline Hydrochloride …
Matched Salts name: … Metronidazole hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinfectives and Antiseptics for Local Oral Treatment ... Antiparasitic Products, Insecticides and Repellents ... Genito Urinary System and Sex Hormones ... metronidazole and diloxanide …
Matched Products: … METRONIDAZOL 0.5% GLAS …

Sulfapyridine

Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Approved
Matched Synonyms: … 2-(p-Aminobenzenesulphonamido)pyridine …
Matched Iupac: … 4-amino-N-(pyridin-2-yl)benzene-1-sulfonamide …
Matched Description: … Antibacterial, potentially toxic, and previously used to treat certain skin diseases. …
Matched Categories: … Benzene Derivatives ... Genito Urinary System and Sex Hormones ... Sulfonamides and trimethoprim ... Gynecological Antiinfectives and Antiseptics …

Tranexamic acid

Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Tranexamic Acid In Sodium Chloride …

2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE

Experimental
Matched Name: … 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE …
Matched Iupac: … 2-[2-phenyl-3-(pyridin-2-yl)-4,5,6,7-tetrahydro-2H-isophosphindol-1-yl]pyridine …

4-[4-(4-Fluorophenyl)-2-[4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine

Experimental
Matched Name: … 4-[4-(4-Fluorophenyl)-2-[4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine …
Matched Iupac: … 4-[4-(4-fluorophenyl)-2-{4-[(R)-methanesulfinyl]phenyl}-1H-imidazol-5-yl]pyridine …

N~3~-[5-(1H-INDOL-6-YL)-2-(PYRIDIN-2-YLMETHOXY)BENZYL]PYRIDINE-2,3-DIAMINE

Experimental
Matched Name: … N~3~-[5-(1H-INDOL-6-YL)-2-(PYRIDIN-2-YLMETHOXY)BENZYL]PYRIDINE-2,3-DIAMINE …
Matched Iupac: … N3-{[5-(1H-indol-6-yl)-2-[(pyridin-2-yl)methoxy]phenyl]methyl}pyridine-2,3-diamine …

Atenolol

Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. Sir James Black, a Scottish pharmacologist, pioneered the use of beta-blockers for the management of angina pectoris in 1958 for which he received the Nobel Prize. Beta-blockers quickly became popular in clinical use and where subsequently investigated for...
Approved
Matched Description: … use in myocardial infarction, arrhythmias, and hypertension during the 1960s. ... [A178429] Beta-blockers quickly became popular in clinical use and where subsequently investigated for ... Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and …
Matched Mixtures name: … Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone ... Atenolol and Chlorthalidone …
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta blocking agents and calcium channel blockers ... atenolol and nifedipine ... atenolol and thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Matched Products: … Septa-atenolol …

Rubella virus vaccine

Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered. It is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus).
Approved
Investigational
Matched Synonyms: … Rubivirus rubella virus Wistar RA 27/3 whole …
Matched Mixtures name: … MEASLES AND RUBELLA VIRUS VACCINE LIVE ... SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 10 doses ... SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 1 dose …
Matched Categories: … measles, combinations with mumps and rubella, live attenuated ... measles, combinations with mumps, rubella and varicella, live attenuated …

Allopurinol

Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and ... It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [ …
Matched Salts name: … Allopurinol sodium …
Matched Products: … Allopurinol sodium …

Morphine

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Description: … [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk ... strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine], and ... Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. …
Matched Salts name: … Morphine hydrochloride ... Morphine hydrochloride trihydrate …
Matched Categories: … morphine and antispasmodics …
Matched Products: … Bar-morphine SR ... MORPHINE HYDROCHLORIDE …

Erlotinib

Erlotinib is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is typically marketed under the trade name Tarceva. Erlotinib binds to the epidermal growth factor receptor (EGFR)...
Approved
Investigational
Matched Description: … EGFR) tyrosine kinase that is used in the treatment of non-small cell lung cancer, pancreatic cancer and ... , which is a mutant form of tyrosine kinase JAK2 found in most patients with polycythemia vera (PV) and ... This finding introduces the potential use of erlotinib in the treatment of JAK2V617F-positive PV and …
Matched Salts name: … Erlotinib hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Erlotinib Hydrochloride …

Ulviprubart

Investigational
Matched Synonyms: … monoclonal ABC008 γ1-chain), disulfide with human-Mus musculus monoclonal ABC008 κ-chain, dime ... Immunoglobulin G1, anti-(human killer cell lectin-like receptor subfamily G member 1) (human-Mus musculus …

(3Z,5S,6R,7S,8S,8aR)-3-(octylimino)hexahydro[1,3]oxazolo[3,4-a]pyridine-5,6,7,8-tetrol

Experimental
Matched Name: … (3Z,5S,6R,7S,8S,8aR)-3-(octylimino)hexahydro[1,3]oxazolo[3,4-a]pyridine-5,6,7,8-tetrol …
Matched Iupac: … (3Z,5S,6R,7S,8S,8aR)-3-(octylimino)-hexahydro-1H-[1,3]oxazolo[3,4-a]pyridine-5,6,7,8-tetrol …
Displaying drugs 1326 - 1350 of 1392 in total