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Displaying drugs 1 - 25 of 4054 in total
Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Synonyms: … Aluminium zirconium octachlorohydrex gly ... Aluminum zirconium octachlorohydrex gly
Matched Name: … Aluminum zirconium octachlorohydrex gly
Matched Description: … Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate …
Matched Products: … Speed Stick Pro Skin ... Speed Stick Pro Clean ... Speed Stick Pro Extra Fresh …
The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Synonyms: … Sebelipasa alfa ... Sebelipase alfa
Matched Name: … Sebelipase alfa
Matched Description: … [L39337] Sebelipase alfa is a recombinant form LAL approved for the treatment of LAL deficiency. …
Matched Categories: … sebelipase alfa
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Synonyms: … Turoctocog alfa
Matched Name: … Turoctocog alfa
Matched Description: … coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally ... Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence ... Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any human- or animal-derived …
Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). Hypophosphatasia is almost always fatal when severe skeletal disease is obvious at birth. By replacing deficient ALP, treatment with Asfotase Alfa aims to improve the elevated enzyme substrate levels...
Approved
Investigational
Matched Synonyms: … Asfotase alfa
Matched Name: … Asfotase alfa
Matched Description: … The annual average price of Asfotase Alfa treatment is $285,000. ... Asfotase Alfa is marketed under the brand name Strensiq® by Alexion Pharmaceuticals, Inc. ... Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying …
Matched Categories: … asfotase alfa
Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Synonyms: … Olipudase alfa
Matched Name: … Olipudase alfa
Matched Description: … Olipudase alfa is recombinant human acid sphingomyelinase. ... [A251590] Olipudase alfa gained its first global approval in Japan on March 28, 2022. ... [A251600] Olipudase alfa works to hydrolyze sphingomyelin accumulated in body tissues, such as the lungs …
Matched Categories: … olipudase alfa
Approved
Investigational
Matched Synonyms: … Lonoctocog alfa
Matched Name: … Lonoctocog alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Dornasa alfa ... Dornase alfa ... Dornase alfa, recombinant …
Matched Name: … Dornase alfa
Matched Description: … Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. ... The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. ... Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products …
Matched Categories: … dornase alfa (desoxyribonuclease) …
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Velmanase alfa ... Velmanase alfa-tycv …
Matched Name: … Velmanase alfa
Matched Description: … [L45295] Velmanase alfa is currently not approved in Canada. ... [A244509] In February 2023, the FDA also approved velmanase alfa for the same indication. ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy …
Matched Categories: … velmanase alfa
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin Alfa
Matched Name: … Thrombomodulin Alfa
Matched Description: … Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). …
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Vonicog alfa
Matched Name: … Vonicog alfa
Matched Description: … Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. ... [L1849] By the EMA, vonicog alfa is still under clinical analysis.[L1862] …
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Interferon alfa-2a ... Interferon-alfa-2a ... Interferon alfa-2a,recombinant …
Matched Name: … Interferon alfa-2a …
Matched Categories: … Alfa Interferons ... interferon alfa-2a …
Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Synonyms: … Peginterferon alfa-2b …
Matched Name: … Peginterferon alfa-2b …
Matched Description: … Peginterferon alfa-2b is derived from the alfa-2b moeity of recombinant human interferon and acts by ... Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat ... Use of Peginterferon alfa-2b is associated with a wide range of severe adverse effects including the …
Matched Categories: … Alfa Interferons ... peginterferon alfa-2b ... peginterferon alfa-2b, combinations …
Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Synonyms: … Albutrepenonacog alfa
Matched Name: … Albutrepenonacog alfa
Matched Description: … Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation …
Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Approved
Matched Synonyms: … Interferon alfa-2b ... Interferon alfa-2b (recombinant) ... Interferon alfa-2b, recombinant …
Matched Name: … Interferon alfa-2b …
Matched Categories: … Alfa Interferons ... interferon alfa-2b …
Matched Products: … INTRON-A 10 MIU/1 ML ENJEKTABL ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Synonyms: … Rurioctocog alfa pegol …
Matched Name: … Rurioctocog alfa pegol …
Matched Description: … [L40119] Rurioctocog alfa pegol is a covalent conjugate of [octocog alfa], which is a recombinant ... Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor ... [A245139] Rurioctocog alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia …
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Name: … Efanesoctocog alfa
Matched Description: … Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the ... [A257464] Efanesoctocog alfa was designed to have an extended half-life, and to surpass the half-life ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza A virus A/Brisbane/10/2010 (H1N1) whole ... Influenza A virus A/Brisbane/10/2010 (H1N1) wild type …
Matched Name: … Influenza A virus A/Brisbane/10/2010 live (attenuated) antigen …
Cucurbita pepo subsp. ovifera whole allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Cucurbita pepo var. ovifera whole …
A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Gly
Matched Mixtures name: … BRAUN 10% ... BRAUN 10% ... Primene 10% …
Red pepper allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Capsicum annuum var. annuum seed …
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Synonyms: … pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 …
Betula pendula pollen allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Betula alba var. pendula pollen …
Evernia prunastri allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Parmelia prunastri var. retusa …
Approved
Experimental
Matched Synonyms: … Calcium 10-undecenoate ... Calcium diundec-10-enoate …
Matched Iupac: … calcium bis(undec-10-enoate) …
Matched Products: … Cruex Medicated Pwr 10% …
Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE and refrigerants, but the latter application is declining. Chloroform is part of...
Approved
Vet approved
Withdrawn
Matched Synonyms: … chloroformium pro narcosi …
Displaying drugs 1 - 25 of 4054 in total