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Displaying drugs 251 - 275 of 6213 in total
Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other...
Approved
Investigational
Matched Iupac: … -1H-cyclopenta[a]phenanthren-2-yl]-1-methylpiperidin-1-ium ... 1-[(1R,2S,3aS,3bR,5aS,7S,8S,9aS,9bS,11aS)-1,7-bis(acetyloxy)-9a,11a-dimethyl-8-(piperidin-1-yl)-hexadecahydro …
Matched Description: … A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. …
Matched Products: … VECURON INYECCION 2 ML (VECURONIO BROMURO 4 MG/ AMPOLLA) ... BROCURIX 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... BROMURO DE VECURONIO 4 MG/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Fostamatinib has been investigated for the treatment and basic science of Rheumatoid Arthritis and Immune Thrombocytopenic Purpura (ITP). It was approved on April 17, 2018, under the trade name Tavalisse for use in ITP [L2644, FDA Label]. Fostamatinib has also been granted orphan drug status by the FDA . Recently,...
Approved
Investigational
Matched Iupac: … {[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2H,3H,4H-pyrido ... [3,2-b][1,4]oxazin-4-yl]methoxy}phosphonic acid …
Matched Description: … It was approved on April 17, 2018, under the trade name Tavalisse for use in ITP [L2644, FDA Label]. ... Recently, fostamatinib has been identified as a potential therapeutic for controlling acute respiratory …
Matched Salts cas: … 914295-16-2
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor (NDRI) used most commonly for the management of Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), and as an aid for smoking cessation. Bupropion exerts its pharmacological effects by weakly inhibiting the enzymes involved in the uptake...
Approved
Matched Iupac: … 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one …
Matched Description: … Bupropion (also known as the brand name product Wellbutrin®) is a norepinephrine/dopamine-reuptake inhibitor ... [A6399,A178840] Lack of activity at these receptors results in a more tolerable side effect profile; ... significant weight loss, with a mean change in body weight of -6.3% compared to -1.3% for placebo. …
Matched Salts cas: … 905818-69-1
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Synonyms: … (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans ... cyclic (6-1)-peptide ... -4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline …
Matched Iupac: … (10R,12S)-N-[(3S,6S,9S,11R,15S,18S,20R,21S,24S,25S)-3-[(1R)-3-amino-1-hydroxypropyl]-21-[(2-aminoethyl ... )amino]-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,25-trihydroxy-15-[(1R)-1-hydroxyethyl …
Matched Description: … Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Salts cas: … 179463-17-3
Matched Products: … CASPOFUNGIN B. BRAUN ... CASPOFUNGINA 50 MG/VIAL POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE ... CASPOVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron...
Approved
Matched Description: … A metallic element found in certain minerals, in nearly all soils, and in mineral waters. …
Matched Mixtures name: … ADDAMEL N ... PNV Tabs 29-1 ... PNV Tabs 29-1
Matched Products: … FERİMAX 100 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 5 AMPUL ... COMPLEJO DE HIDROXIDO DE HIERRO EN SACAROSA EQUIVALENTE A 100 MG DE HIERRO ELEMENTAL INYECTABLE …
Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives . Bronopol is used as a microbicide or microbiostat...
Approved
Matched Synonyms: … 2-Bromo-2-nitropropane-1,3-diol ... 2-Nitro-2-bromo-1,3-propanediol …
Matched Iupac: … 2-bromo-2-nitropropane-1,3-diol …
Matched Description: … Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial ... First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was ... Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Description: … Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting ... complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B) ... potency and efficacy, particularly when used for the treatment of bleeding associated with Hemophilia B
Matched Products: … BERIPLEX P/N 250 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... BERIPLEX P/N 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Aurothioglucose, also known as gold thioglucose, was formerly used to treat rheumatoid arthritis. Contemporary research on the effect of gold salts treatment began in 1935, primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis . The use of gold compounds has decreased since the 1980s...
Approved
Withdrawn
Matched International brands: … Solganal B
Matched Iupac: … {[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanyl}gold …
Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women. Bremelanotide does not interact with alcohol. The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown. Bremelanotide was first described in the literature in 2003 when it...
Approved
Investigational
Matched Description: … [A179689] Bremelanotide was granted FDA approval on 21 June 2019.[L9635] ... Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal ... [A179686] The mechanism by which bremelanotide's action on receptors translates to a clinical effect …
Matched Salts cas: … 1607799-13-2
Matched Categories: … Receptor, Melanocortin, Type 3, agonists …
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Description: … L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and ... the World Health Organization's List of Essential Medicines, the most important medications needed in a
Matched Mixtures name: … Isolyte H in Dextrose ... N-ORS Oral Rehydration Salts (Orange Flavour) ... Acd-A
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … B. BRAUN 50% GLUCOSE INJECTION BP ... B. BRAUN 5% GLUCOSE IV INFUSION BP ... B. BRAUN 20% GLUCOSE IV INFUSION BP …
Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as...
Approved
Nutraceutical
Matched Description: … The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. ... Lysine is a base, as are arginine and histidine. …
Matched Salts cas: … 657-27-2 ... 57282-49-2
Matched Mixtures name: … ONE A DAY TABLET ... AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML …
Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Although the risk of developing febrile neutropenia...
Approved
Matched Description: … conjugated to the N-terminus of filgrastim (at the methionine residue) to develop longer-acting pegfilgrastim ... It is typically administered via a subcutaneous injection. ... Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … ENJEKSIYON ICIN KULLANIMA HAZIR SIRINGA, 1 ADET ... Pelgraz 6 mg solution for injection in a pre-filled syringe ... NUFILONG SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 6MG/0.6ML …
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Description: … [A245854] B-cell maturation antigen (BCMA) is a transmembrane glycoprotein member of the tumor necrosis ... [L40739] Patient T-cells are reprogrammed with a transgene encoding a specific chimeric antigen receptor ... Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. …
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … Compared to [pembrolizumab], a smaller proportion of patients experienced grade 3-4 adverse events (4% ... [A255111] Nadofaragene firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer ... serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). …
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Synonyms: … 2,4,4'-Trichloro-2'-hydroxydiphenyl ether ... 5-Chloro-2-(2,4-dichloro-phenoxy)-phenol …
Matched Iupac: … 5-chloro-2-(2,4-dichlorophenoxy)phenol …
Matched Description: … An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, …
Matched Mixtures name: … PREVENT 2 EN 1 ... KURSEPT %19 + %1 KREM (30 G) ... APRIL Bath and Shower Anti-bacterial Hand 3 Pack …
Matched Products: … Pier 1 Imports Sweet Orange Anti-bacterial Hand Wash N/A ... Pier 1 Imports Sweet Grape Anti-bacterial Hand Wash N/A ... Pier 1 Imports Sweet Cherry Anti-bacterial Hand Wash N/A
Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that is produced as an oral fluid in the alimentary canal of the male blister beetle.[A32891, A32892] For its natural purpose, the male blister beetle secretes and presents the cantharidin to a female beetle as a copulatory...
Approved
Investigational
Matched Description: … [L47496] The approval was based on positive results from 2 phase III trials, CAMP-1 and CAMP-2, where ... female beetle as a copulatory gift during mating. ... Cantharidin is a naturally occurring odorless, colorless fatty substance of the terpenoid class that …
Matched Mixtures name: … CANTHACUR PS %1,%5,%30 TOPIKAL SOLUSYON 7,5 ML ... Cantharidin 1% / Podophyllum Resin 5% / Salicylic Acid 30% …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
Approved
Matched Description: … Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of ... B. anthracis toxin. ... Raxibacumab has a molecular weight of approximately 146 kilodaltons. …
Matched Categories: … Anthrax Protective Antigen-directed Antibody ... Anthrax Protective Antigen-directed Antibody Interactions …
Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.
Approved
Matched Synonyms: … 2-(p-bromo-α-phenylbenzyloxy)-N,N-dimethylethylamine …
Matched Iupac: … {2-[(4-bromophenyl)(phenyl)methoxy]ethyl}dimethylamine …
Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from one of the first blood samples in the United States from a patient who recovered from COVID-19.[A224039, L15311, L15316] Bamlanivimab is a neutralizing IgG1κ mAb directed against the SARS-CoV-2 spike (S) protein, which is described to...
Approved
Investigational
Matched Description: … [L20979] Based on phase 2 clinical trial (BLAZE-1) interim results, bamlanivimab was granted Emergency ... [A224039, L15311, L15316] Bamlanivimab is a neutralizing IgG1κ mAb directed against the SARS-CoV-2 spike ... [A224044, L20974] It is set to enter phase 3 clinical trials. …
Hydrocortamate is a synthetic glucocorticoid used for its anti-inflammatory or immunosuppressive properties to treat inflammation due to corticosteroid-responsive dermatoses. Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects.
Approved
Matched Iupac: … ,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl 2-(diethylamino)acetate ... 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Description: … Hydrocortamate is a synthetic glucocorticoid used for its anti-inflammatory or immunosuppressive properties ... Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol ... receptor and trigger a variety of important cardiovascular, metabolic, immunologic and homeostatic effects …
Matched Salts cas: … 125-03-1
Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Synonyms: … (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ... 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. ... [A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition …
Matched Salts cas: … 23325-78-2 ... 105879-42-3
Matched Categories: … Heterocyclic Compounds, 2-Ring ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Products: … KEFLEX 1 G TABLETAS ... MAKSIPOR 1 GR FILM TABLET, 10 ADET ... MAKSIPOR 1 GR FILM TABLET, 20 ADET …
Bethanechol is a synthetic ester that was initially synthesized in 1935.[A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function to acetylcholine and is used in specific cases when stimulation of the parasympathetic nervous system is necessary.[A232905,L32539] For example, bethanechol is readily used to treat postoperative or...
Approved
Matched Synonyms: … 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium ... 2-carbamoyloxypropyl-trimethylazanium ... (2-hydroxypropyl)trimethylammonium carbamate …
Matched Iupac: … 1-(trimethylazaniumyl)propan-2-yl carbamate …
Matched Description: … Bethanechol is a synthetic ester that was initially synthesized in 1935. ... [A232905,L32539] As a cholinergic agent, bethanechol is similar in structure and pharmacological function …
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … under investigations for potential therapeutic use in diseases driven by allergic reactions or type 2 ... Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin ... [L7186] Dupilumab is commonly marketed as Dupixent, which is available as a formulation for subcutaneous …
Matched Products: … DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 200 mg/1.14ml ... DUPİXENT 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Iupac: … 2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl furan-2-carboxylate ... (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-1-(2-chloroacetyl)-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H, …
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Mixtures name: … M-FURO MANT % 0.1 + % 1 KREM, 20G ... M-FURO FA %0.1 + %2 KREM, 30 G ... MATEC 2/200 MCG INHALASYON TOZ IÇEREN KAPSÜL , 60 KAPSÜL …
Matched Products: … Monovo 1 mg/g Creme ... Momecutan 1 mg/g Creme ... Momecutan 1 mg/g Salbe …
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … L36325] Filgrastim-sndz was approved on March 6, 2015 [L40768] and filgrastim-ayow was approved on March 2, ... sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal ... Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor ( …
Matched Products: … FRAVEN 30 MIU/0,5 ML IV INFUZYON/SC ENJEKSIYON ICIN COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 3 ADET ... ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML ... ACCOFIL 30 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 30 MU/0.5 ML …
Displaying drugs 251 - 275 of 6213 in total