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Displaying drugs 2976 - 2987 of 2987 in total

Gliclazide

Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It has been classified differently according to its drug properties in which based on its chemical structure, gliclazide is considered a first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release...
Approved
Matched Description: … increase the number and sensitivity of insulin receptors. ... first-generation sulfonylurea due to the structural presence of a sulfonamide group able to release a proton and ... Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Mint-gliclazide Mr …

Quetiapine

Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Description: … as [clozapine] and [olanzapine]. ... , quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and ... [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … Q-MIND ... Mint-quetiapine ... Mint-quetiapine XR …

Irbesartan

Irbesartan is an angiotensin receptor blocker (ARB) indicated to treat hypertension or diabetic nephropathy.[L7456,L7459] It can also be used as part of a combination product with hydrochlorothiazide for patients not well controlled or not expected to be well controlled on monotherapy. Unlike angiotensin converting enzyme inhibitors, ARBs are not associated...
Approved
Investigational
Matched Mixtures name: … Mint-irbesartan/hctz ... Mint-irbesartan/hctz ... Mint-irbesartan/hctz …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... irbesartan and diuretics ... irbesartan and amlodipine ... irbesartan, amlodipine and hydrochlorothiazide …
Matched Products: … Mint-irbesartan …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … Sitagliptin Phosphate/Metformin Hydrochloride ... JANUMET 50/850MG (SITAGLIPTIN PHOSPHATE/METFORMIN HCI) ... JANUMET 50/500MG (SITAGLIPTIN PHOSPHATE/METFORMIN HCI) …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and sulfonylureas ... metformin and gemigliptin ... metformin and linagliptin …
Matched Products: … Mint-metformin ... Sitagliptin/metfor Min Hydrochloride Mylan …

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no ... choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and …
Matched Products: … Mint-levetiracetam ... Levetiracetam in Sodium Chloride …

Losartan

Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … Mint-losartan/hctz ... Mint-losartan/hctz ... Mint-losartan/hctz DS …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Angiotensin II receptor blockers (ARBs) and diuretics ... losartan and diuretics ... losartan and amlodipine …
Matched Products: … Mint-losartan …

Venlafaxine

Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). ... Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine ... treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Mint-venlafaxine XR …

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … Mint-donepezil ... ANDEM 10 MG FILM TABLET, 14 ADET ... ANDEM 10 MG FILM TABLET, 28 ADET …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Description: … it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... muscle relaxation and vasodilation that subsequently facilitates relief in pulmonary arterial hypertension …
Matched Products: … Mint-sildenafil …

Amlodipine

Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), ... Amlodipine is commonly used in the treatment of high blood pressure and angina. ... associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine Besylate and Atorvastatin Calcium …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... Angiotensin II Antagonists and Calcium Channel Blockers ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … Mint-amlodipine …

Tadalafil

Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Description: … that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and ... [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and …
Matched Categories: … Genito Urinary System and Sex Hormones ... ambrisentan and tadalafil ... tamsulosin and tadalafil ... finasteride and tadalafil ... macitentan and tadalafil …
Matched Products: … Mint-tadalafil …

Risperidone

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Description: … mental health conditions including schizophrenia and bipolar disorder. ... Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and ... D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical …
Matched Products: … Mint-risperidon …
Displaying drugs 2976 - 2987 of 2987 in total