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Displaying drugs 26 - 50 of 691 in total

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

Calcium polycarbophil

Calcium polycarbophil is a stool stabilizer. Based on its chemical structure, it is a synthetic polymer of polyacrylic acid cross-linked with divinyl glycol presenting a calcium atom as a counter-ion. Polycarbophil is used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel...
Approved
Matched Synonyms: … Calcium polycarbophil ... Polycarbophil calcium ... Polycarbophil, calcium …
Matched Name: … Calcium polycarbophil …
Matched Description: … Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps ... It is insoluble in water, dilute acids, and dilute alkali. ... digestive enzymes or intestinal absorption, possesses satisfactory stability, is physiologically inert, and …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium Salts ... polycarbophil calcium …
Matched Products: … Up and Up Fiber Therapy ... Foster and Thrive Fiber Laxative 147 ... Calcium Polycarbophil …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

Stannous fluoride

Stannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective...
Approved
Matched Description: … It manages and prevents dental caries and gingivitis by promoting enamel mineralization [A19580], reducing ... compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and ... effect and modulation of the microbial composition of the dental biofilm [A19581]. …
Matched Mixtures name: … Perfect Choice 0.717% Root and Dentin Desens …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up Anticavity Toothpaste Multi Function ... Sensodyne Sensitivity and Gum Clean and Fresh ... Crest Sensi-Repair and Prevent …

Petrolatum

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … Ice Lipbalm - Stk Top ... Ice Lipbalm SPF 12- Stk Top ... Natural Ice Lipbalm SPF 14.7-stk Top …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Vitamin A and D ... A and D ... UP and UP …

PMC-403

PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Matched Synonyms: … a fully human monoclonal antibody that binds and activates the Tie2 receptor …

TSHA-101

Investigational
Matched Synonyms: … adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric ... has structural and functional characteristics similar to those of endogenous factor IX. ... has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and …
Matched Products: … BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Benzocaine

Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and …
Matched Mixtures name: … Topco 4x Medicated Toothache and Gum Gel ... BENZOCAINE and RESORCINOL ... BENZOCAINE and RESORCINOL …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Topex ... Sting and Bite ... Bite and Sting relief …

Menthol

Approved
Matched Mixtures name: … Topco 4x Medicated Toothache and Gum Gel ... Top Medicated ... AA Top Medicated …
Matched Products: … Top Care Medicated ... Muscle and Joint ... Muscle and Joint Vanishing Scent Fast Penetrating …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature …

Chlorine dioxide

Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
Investigational
Matched Name: … Chlorine dioxide …
Matched Description: … Chlorine Dioxide has been used in trials studying the treatment of Halitosis. …
Matched Products: … Disinfectant and Sanitizer ... Chlorine Dioxide Air Disinfectant …

Menotropins

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … MENOPUR multidose 600IU Powder and Solvent for Solution for Injection ... MENOPUR multidose 1200IU Powder and Solvent for Solution for Injection ... Menopur Powder for Injection and Solvent 75 IU …

MM-111

MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

CLL1-CD33 compound chimeric antigen receptor T cells

Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … disinfection and surgical instruments. ... Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin ... It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … HACCP Flat Top E-2 ... Uscalrite Tec E-1 - Liq Top 0.5% ... Spartan E2 Hand Wash and Sanitizer …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … ADVATE 250IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 500IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 1000IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg …

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …

DCVAC/OvCa

DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …
Displaying drugs 26 - 50 of 691 in total