Displaying drugs 26 - 50 of 2880 in total
Human varicella-zoster immune globulin
Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the...
Approved
Matched Synonyms: … Human herpesvirus 3 immune globulin ... Varicella zoster immune globulin human ... Varicella zoster immune globulin (human) …
Matched Name: … Human varicella-zoster immune globulin …
Matched Description: … human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). ... Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified ... It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and …
Matched Categories: … Complex Mixtures ... Human Varicella Zoster Immune Globulins …
Matched Products: … Varicella-zoster Immune Globulin (human) …
Matched Name: … Human varicella-zoster immune globulin …
Matched Description: … human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). ... Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified ... It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and …
Matched Categories: … Complex Mixtures ... Human Varicella Zoster Immune Globulins …
Matched Products: … Varicella-zoster Immune Globulin (human) …
Human interferon beta
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … HUMAN INTERFERON BETA ... Interferon beta (human) …
Matched Name: … Human interferon beta …
Matched Description: … Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis …
Matched Name: … Human interferon beta …
Matched Description: … Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis …
Human vaccinia virus immune globulin
Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody [FDA Label, A33814]. The IgG fraction is purified by the anion-exchange column chromatography...
Approved
Matched Synonyms: … Human vaccinia immune globulin ... Vaccinia Immune Globulin (Human) Intravenous ... Vaccinia immune globulin intravenous (human) …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG ... Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human …
Matched Categories: … Human Immunoglobulin G …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG ... Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human …
Matched Categories: … Human Immunoglobulin G …
Drotrecogin alfa
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Blood coagulation factor XIV (human) ... Recombinant human activated protein C (rH-APC) …
Matched Description: … Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Blood Coagulation Factor Inhibitors …
Matched Description: … Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. …
Matched Categories: … Blood Coagulation Factor Inhibitors …
Human botulinum neurotoxin A/B immune globulin
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin IV human ... Botulism immune globulin intravenous (human) ... Human-derived botulism antitoxin antibodies …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in …
Matched Categories: … Human Immunoglobulin G …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in …
Matched Categories: … Human Immunoglobulin G …
Sargramostim
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational
Matched Synonyms: … Recombinant human granulocyte-macrophage colony stimulating factor …
Matched Description: … Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed …
Matched Categories: … Leukocyte Growth Factor ... Granulocyte-Macrophage Colony-Stimulating Factor …
Matched Description: … Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed …
Matched Categories: … Leukocyte Growth Factor ... Granulocyte-Macrophage Colony-Stimulating Factor …
Human papillomavirus type 11 L1 capsid protein antigen
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 11 Vaccine ... Recombinant human papillomavirus type 11 L1 protein …
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Human papillomavirus type 58 L1 capsid protein antigen
Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 58 Vaccine ... Recombinant human papillomavirus type 58 L1 protein …
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Becaplermin
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Synonyms: … Platelet-derived growth factor BB, recombinant ... Recombinant platelet-derived growth factor BB ... Platelet-derived growth factor beta polypeptide …
Matched Description: … produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor …
Matched Categories: … Human Platelet-derived Growth Factor ... Platelet-Derived Growth Factor …
Matched Description: … produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor …
Matched Categories: … Human Platelet-derived Growth Factor ... Platelet-Derived Growth Factor …
Corticorelin ovine triflutate
Corticorelin, available commercially as corticorelin ovine triflutate (tradename Acthrel), is a synthetic form of the peptide human corticotropin-releasing hormone (hCRH), a potent stimulator of adrenocorticotropic hormone (ACTH) release from the anterior pituitary. Endogenous forms hCRH are involved in the stress response and its main function is stimulation of the pituitary...
Approved
Matched Synonyms: … Ovine ACTH releasing factor ... Ovine corticotropin-releasing factor ... Corticotropin-releasing factor (sheep) …
Matched Description: … commercially as corticorelin ovine triflutate (tradename Acthrel), is a synthetic form of the peptide human …
Matched Description: … commercially as corticorelin ovine triflutate (tradename Acthrel), is a synthetic form of the peptide human …
Lenograstim
Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Synonyms: … Granulocyte colony-stimulating factor lenograstim ... Granulocyte colony stimulating factor 3 (CHO cell derived) ... Glycosylated recombinant granulocyte colony stimulating factor …
Matched Description: … Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent …
Matched Description: … Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent …
Damoctocog alfa pegol
In recent years, various extended half-life factor VIII and factor IX preparations have been studied and gained approval. In order to extend half-lives, techniques such as fusion to protein conjugates (Fc part of IgG1 or albumin), chemical modification (PEGylation), and protein sequence modification have been utilized. Also known as, BAY94-9027,...
Approved
Investigational
Matched Description: … In recent years, various extended half-life factor VIII and factor IX preparations have been studied ... [A38907]
Also known as, BAY94-9027, Damoctocog alfa pegol is a longer-acting Factor VIII therapy formulated …
Matched Categories: … Blood Coagulation Factors …
Matched Categories: … Blood Coagulation Factors …
Emicizumab
Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. ... Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation ... factors allows it to overcome immunogenicity and unstable hemostatic efficacy produced by previous Factor …
Matched Categories: … Blood Coagulation Factors …
Matched Categories: … Blood Coagulation Factors …
Apadamtase alfa
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant human adamts13 ... Metalloproteinase ADAMTS13 (human recombinant BAX930) …
Matched Description: … Willebrand factor multimers and preventing the formation of microthrombi - this deficiency in ADAMTS13 ... metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible for cleaving large von …
Matched Description: … Willebrand factor multimers and preventing the formation of microthrombi - this deficiency in ADAMTS13 ... metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible for cleaving large von …
Iron sucrose
Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Synonyms: … Iron sucrose complex ... Ferric hydroxide sucrose complex ... Iron(III) hydroxide sucrose complex …
Citrus bioflavonoids
Approved
Experimental
Matched Synonyms: … Hesperidin complex …
Matched Mixtures name: … NATURERICH ESTER-C COMPLEX TABLETS …
Matched Mixtures name: … NATURERICH ESTER-C COMPLEX TABLETS …
Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen
Approved
Investigational
Matched Name: … Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen …
Conestat alfa
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Recombinant human C1-INH ... Recombinant human C1 inhibitor ... Recombinant human C1-inhibitor …
Matched Description: … XIIa and factor XIa. ... C1 esterase inhibitor has also been shown to inhibit the action of thrombin within the coagulation pathway ... through inhibition of several target proteases within these pathways including activated C1s, kallikrein, factor …
Matched Description: … XIIa and factor XIa. ... C1 esterase inhibitor has also been shown to inhibit the action of thrombin within the coagulation pathway ... through inhibition of several target proteases within these pathways including activated C1s, kallikrein, factor …
Plasminogen
Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved
Matched Synonyms: … Human plasminogen ... plasminogen, human-tvmh …
Matched Description: … [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh …
Matched Description: … [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh …
Etanercept
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Synonyms: … Recombinant human TNF …
Matched Description: … (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. ... Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton …
Matched Categories: … Tumor Necrosis Factor Blockers ... Tumor necrosis factor alpha (TNF-alpha) inhibitors …
Matched Description: … (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. ... Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton …
Matched Categories: … Tumor Necrosis Factor Blockers ... Tumor necrosis factor alpha (TNF-alpha) inhibitors …
Remestemcel-L
Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal stem cells intended for intravenous infusion. The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen (HLA)–unmatched healthy adult donors and have the ability to differentiate into different tissue cells. It was...
Approved
Investigational
Matched Synonyms: … Adult human mesenchymal stem cells ... Allogeneic human mesenchymal stem cell …
Matched Description: … Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal ... The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen ... Human mesenchymal stem cells (hMSCs) serve to down-regulate inflammatory responses and produce anti-inflammatory …
Matched Categories: … Complex Mixtures …
Matched Description: … Remestemcel-L is a third-party, off-the-shelf suspension of ex-vivo cultured adult human mesenchymal ... The mesenchymal stem cells are derived from the bone marrow of unrelated and human leukocyte antigen ... Human mesenchymal stem cells (hMSCs) serve to down-regulate inflammatory responses and produce anti-inflammatory …
Matched Categories: … Complex Mixtures …
Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Synonyms: … WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 LIGHT CHAIN, DIMER ... WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18/CHO LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(GANGLIOSIDE GD2) (HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 HEAVY CHAIN), DISULFIDE …
Matched Description: … It is indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin ... Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed ... on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted …
Matched Description: … It is indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin ... Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed ... on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted …
Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Microplasmin (synthetic human) ... Recombinant human microplasmin …
Matched Description: … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Description: … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Antithymocyte immunoglobulin (rabbit)
Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Synonyms: … Rabbit anti-human thymocyte globulin ... Anti-human thymocyte immunoglobulin, rabbit ... Rabbit anti-human thymocyte immunoglobulin …
Matched Categories: … Complex Mixtures …
Matched Categories: … Complex Mixtures …
Belzutifan
Belzutifan is an inhibitor of hypoxia-inducible factor 2α (HIF-2α) used in the treatment of von Hippel-Lindau (VHL) disease-associated cancers. The HIF-2α protein was first identified in the 1990s by researchers at UT Southwestern Medical Center as a key player in the growth of certain cancers. Initially considered to be undruggable,...
Approved
Investigational
Matched Description: … Belzutifan is an inhibitor of hypoxia-inducible factor 2α (HIF-2α) used in the treatment of von Hippel-Lindau ... a necessary step in its activation - by preventing the formation of this complex, belzutifan can slow ... [L36105]
Belzutifan inhibits the complexation of HIF-2α with another transcription factor, HIF-1β, …
Matched Categories: … Hypoxia-inducible Factor Inhibitor …
Matched Categories: … Hypoxia-inducible Factor Inhibitor …
Displaying drugs 26 - 50 of 2880 in total