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Displaying drugs 26 - 50 of 10290 in total

Pentoxifylline

Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched International brands: … An Ruo Ning …
Matched Description: … 1972; PTX extended-release tablets sold under the trade name TRENTAL by US Pharm Holdings were first approved …
Matched Categories: … Antiplatelet agents ... Cardiovascular Agents ... Hematologic Agents ... Protective Agents ... Vasodilating Agents …
Matched Products: … Truemed Group LLC …

Flupentixol

Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Description: … Flupentixol is an antipsychotic drug of the thioxanthene group. ... It is approved for use in Canada and other countries around the world, but not in the US. ... [A229083] Flupentixol is an antagonist of both D1 and D2 dopamine receptors. …
Matched Categories: … Antidepressive Agents ... Dopamine Agents ... Antipsychotic Agents ... Neurotoxic agents ... Serotonin Agents …

Opium

Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … Opium is the first substance of the diverse group of the opiates. ... This plant is an integrant of the Papaveraceae family, and it is characterized by solitary leaves and ... of phenanthrenes and alkaloids that have no central nervous system effect in the category of isoquinolines …
Matched Categories: … Antitussive Agents ... Sensory System Agents ... Gastrointestinal Agents ... Respiratory System Agents ... Central Nervous System Agents …

Baloxavir marboxil

Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.[A39895, A251755] It is a prodrug of baloxavir with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl...
Approved
Investigational
Matched Description: … active metabolite due to the addition of a phenolic hydroxyl group to its structure. ... Baloxavir marboxil is an antiviral drug used to treat influenza. ... [L4779] It was also approved by the European Commission on January 7, 2021.[L45241] …
Matched Categories: … Antiviral Agents ... Anti-Infective Agents …

Parecoxib

Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral...
Approved
Matched Description: … Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx ... It is approved through much of Europe for short term perioperative pain control much in the same way …
Matched Categories: … Antirheumatic Agents ... Nephrotoxic agents ... Agents causing hyperkalemia ... Anti-Inflammatory Agents ... Sensory System Agents …

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Description: … Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Second-Generation ... Antidepressive Agents Indicated for Depression ... Anti-Anxiety Agents ... Serotonin Agents …

Cholestyramine

Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water.
Approved
Investigational
Matched Categories: … Anticholesteremic Agents ... Hypolipidemic Agents ... Lipid Modifying Agents ... Lipid Regulating Agents ... Lipid Modifying Agents, Plain …

Ziprasidone

Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Description: … [A180748] Although ziprasidone is classified as an atypical antipsychotic, it appears to have a lower …
Matched Categories: … Antidepressive Agents ... Dopamine Agents ... Antipsychotic Agents ... Anticholinergic Agents ... Serotonin Agents …
Matched Products: … Truemed Group LLC …

Benzylpenicillin

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms. Natural penicillins are considered...
Approved
Vet approved
Matched Description: … The natural penicillins may also be used as first or second line agents against susceptible gram positive ... D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. ... Aminoglycosides may be added for synergy against group B streptococcus (*S. agalactiae*), *S. viridans …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …

Estradiol cypionate

Estradiol Cypionate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol cypionate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Description: … Estradiol cypionate is commercially available as Depo-Estradiol, an intramuscular depot injection used ... [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability …
Matched Mixtures name: … Truemed Group LLC …
Matched Categories: … Contraceptive Agents, Female ... Contraceptive Agents, Hormonal ... Reproductive Control Agents …

Dimethicone

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Categories: … Antifoaming Agents ... Skin and Mucous Membrane Agents …
Matched Products: … An Adc Wrinkle ... KVG Group, Inc. FXP Cracked Heel Formula ... An Adc Sp Intensive Wrinkle …

Nomifensine

Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Description: … The approved application holder removed Merital capsules from the market on January 23, 1986. ... Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic …
Matched Categories: … Antidepressive Agents ... Dopamine Agents ... Neurotransmitter Agents …

Dihydro-alpha-ergocryptine

Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. Both compounds are hydrogenated ergot derivatives. Alpha-dihydroergocryptine approved drug product...
Approved
Matched Description: … Alpha-dihydroergocryptine approved drug product is as a part of an ergoloid mixture. ... These two compounds are differentiated in the position of a methyl group. …

Fluticasone

Fluticasone is a synthetic glucocorticoid available as 2 esters, DB08906 and DB00588[F4355,F4358,F4361,F4364][FDA Label]. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications[F4355,F4358,F4361,F4364][FDA Label]. DB00588 was first approved in 1990 and DB08906 was approved in 2007 .
Approved
Experimental
Matched Description: … [DB00588] was first approved in 1990[L5962] and [DB08906] was approved in 2007[L5965]. …
Matched Categories: … Corticosteroids, Potent (Group III) ... Autonomic Agents ... Anti-Allergic Agents ... Anti-Asthmatic Agents ... Bronchodilator Agents …

Rezafungin

Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Description: … Rezafungin is an echinocandin antifungal drug. ... [A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and …
Matched Categories: … Antifungal Agents ... Anti-Infective Agents ... Photosensitizing Agents …

Demeclocycline

A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Photosensitizing Agents ... Agents that produce neuromuscular block (indirect) …

Hemoglobin

The respiratory protein of the red blood cells. It consists primarily of globin and heme.
Approved
Experimental
Investigational

Rosuvastatin

Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an ... lovastatin], and [simvastatin], which are all extensively metabolized by Cytochrome P450 (CYP) 3A4, an …
Matched Categories: … Anticholesteremic Agents ... Hypolipidemic Agents ... Agents Causing Muscle Toxicity ... Lipid Modifying Agents ... Lipid Regulating Agents …
Matched Products: … ROSUVASTATINA TEVA GROUP ... Rosuvastatin Actavis Group 5 mg Filmtabletten ... Rosuvastatin Actavis Group 10 mg Filmtabletten …

Betaine

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Description: … Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. ... [A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine ... The FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment …
Matched Categories: … Lipotropic Agents ... Gastrointestinal Agents ... Lipid Regulating Agents ... Other Miscellaneous Therapeutic Agents …

Vaborbactam

Vaborbactam is a β-lactamase inhibitor based on a cyclic boronic acid pharmacophore. It has been used in trials investigating the treatment of bacterial infections in subjects with varying degrees of renal insufficiency. In August 2017, a combination antibacterial therapy under the market name Vabomere was approved by the FDA for...
Approved
Investigational
Matched Description: … In August 2017, a combination antibacterial therapy under the market name Vabomere was approved by the …
Matched Categories: … Anti-Infective Agents …

Ulobetasol

Ulobetasol is a highly potent corticosteroid. It is structurally related to clobetasol. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.
Approved
Matched Categories: … Corticosteroids, Potent (Group III) ... Cardiovascular Agents ... Anti-Inflammatory Agents ... Vasoconstrictor Agents ... Immunosuppressive Agents …

Clocortolone

Clocortolone is a medium potency corticosteroid that is often used as a topical cream for the relief of inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp.
Approved
Matched Categories: … Corticosteroids, Moderately Potent (Group II) ... Anti-Inflammatory Agents ... Immunosuppressive Agents …

Medroxyprogesterone acetate

Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also...
Approved
Investigational
Matched Mixtures name: … Truemed Group LLC …
Matched Categories: … Antineoplastic Agents ... Contraceptive Agents, Male ... Antineoplastic Agents, Hormonal ... Contraceptive Agents, Female ... Contraceptive Agents, Hormonal …

Technetium Tc-99m tetrofosmin

Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin. It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit...
Approved
Matched Description: … [A31592] Technetium Tc-99m tetrofosmin was developed by GE Healthcare and FDA approved on February 9, ... lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit which yields an ... technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group …

Loracarbef

Loracarbef is a carbacephem antibiotic sometimes grouped together with the second-generation cephalosporin antibiotics. It is marketed under the trade name Lorabid.
Approved
Investigational
Withdrawn
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Nephrotoxic agents …
Displaying drugs 26 - 50 of 10290 in total