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Displaying drugs 476 - 500 of 584 in total
A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Approved
Investigational
Matched Products: … TOLVON 30 MG TABLET, 14 ADET ... TOLVON 30 MG FİLM KAPLI TABLET, 14 ADET …
Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). For these purposes, sunitinib is generally available as an orally administered formulation....
Approved
Investigational
Matched Description: … cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). ... In addition, sunitinib inhibits other RTKs including RET, CSF-1R, and flt3. ... These include all platelet-derived growth factor receptors (PDGF-R) and vascular endothelial growth factor …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … SUTENT 50 MG KAPSUL, 14 ADET ... SUNO 50 MG SERT KAPSÜL, 14 ADET ... SUTESGO 50 MG SERT KAPSÜL, 14 ADET …
Approved
Experimental
Matched Synonyms: … Ginger root oil ... Ginger root oil china ... Ginger root oil cochin …
Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Description: … [FDA Label] Due to their good safety profile and as several PPIs are available over the counter without ... and bone fractures later in life. ... B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis …
Matched Categories: … Alimentary Tract and Metabolism ... pantoprazole, amoxicillin and clarithromycin ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... pantoprazole, amoxicillin, clarithromycin and metronidazole …
Matched Products: … PANTPAS 40 MG TABLET, 14 ADET ... STAMIC 40 MG ENTERIK TABLET, 14 ADET ... ABPAX 40 MG ENTERIK KAPLI TABLET, 14 ADET …
Fesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Approved
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … TOVIAZ 4 MG UZATILMIS SALIMLI TABLET, 14 ADET ... TOVIAZ 8 MG UZATILMIS SALIMLI TABLET, 14 ADET ... FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 14 ADET …
Atractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Atractyloides Japonica Root Oil …
Matched Name: … Atractylodes lancea root oil …
Matched Description: … Atractylodes lancea root oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Brivaracetam is a racetam derivative of levetiracetam used in the treatment of partial-onset seizures. Brivaracetam binds SV2A with 20 times higher affinity than levetiracetam . It is available under the brand name Briviact made by UCB. Briviact received FDA approval on February 19, 2016 .
Approved
Investigational
Matched Description: … Briviact received FDA approval on February 19, 2016 [L760]. …
Matched Products: … BRIVIACT 10 MG FILM KAPLI TABLET ,14 FILM KAPLI TABLET ... BRIVIACT 100 MG FILM KAPLI TABLET ,14 FILM KAPLI TABLET ... BRIVIACT 25 MG FILM KAPLI TABLET ,14 FILM KAPLI TABLET …
Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where...
Approved
Investigational
Matched Synonyms: … Synthetic somatostatin-14
Matched Description: … Prosomastatin is further process into two active forms, somatostatin-14 (SST-14) and somatostatin-28 ... It is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also ... generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Pertuzumab is a recombinant humanized monoclonal antibody that targets the extracellular dimerization domain (subdomain II) of the human epidermal growth factor receptor 2 protein (HER2). It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. It was first approved by the FDA in...
Approved
Matched Description: … It was first approved by the FDA in 2012 for use with [docetaxel] and another HER2-targeted monoclonal ... It consists of two heavy chains and two lights chains that have 448 and 214 residues respectively. ... Its indicated conditions have since expanded to include use as both a neoadjuvant therapy and an adjuvant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … PERJETA 420 MCG/14 ML KONSANTRE İNFÜZYON ÇÖZELTİSİ ... PERJETA CONCENTRATE FOR SOLUTION FOR INFUSION 420MG/14ML ... PERJETA® 420 MG/14 ML SOLUCIÓN CONCENTRADA PARA INFUSIÓN …
Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Description: … ., and received FDA approval in 1997 for the treatment of major depressive disorder. ... prevent nausea and vomiting after surgery. ... symptoms of neurological disorders, reverse weight loss caused by medical conditions, improve sleep, and
Matched Products: … MIRES 15 MG FILM TABLET, 14 ADET ... MIRES 30 MG FILM TABLET, 14 ADET ... MIRES 45 MG FILM TABLET, 14 ADET …
Curcuma aromatica root oil is obtained from the roots of Curcuma aromatica, or more commonly called wild tumeric, via steamed distillation. Curcuma aromatica belongs to the family Zingiberaceae. The wild ginger has been used as a cosmetic herbal where its rhizomes exhibit a distinct fragrance and color. The major constituents...
Approved
Matched Name: … Curcuma aromatica root oil …
Matched Description: … , ar-turmerone and 1,8-cineole [A27219]. ... The wild ginger has been used as a cosmetic herbal where its rhizomes exhibit a distinct fragrance and ... Curcuma aromatica root oil is obtained from the roots of *Curcuma aromatica*, or more commonly called …
Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys,...
Approved
Investigational
Matched Description: … Therapeutics' brand name Galafold was approved using the Accelerated Approval pathway, under which the FDA ... in patients with Fabry disease, builds up in the blood vessels, the kidneys, the nerves, the heart, and ... L4274,L4278] In the U.S., it is estimated that more than 3,000 people are living with Fabry disease, and
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Products: … GALAFOLD 123 MG SERT KAPSÜL, 14 ADET …
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … and stimulated gastric acid secretion. ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal …
Matched Mixtures name: … RASOFORCE 20/1680 MG TOZ İÇEREN SAŞE, 14 SAŞE …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... rabeprazole, amoxicillin and metronidazole ... rabeprazole, amoxicillin and clarithromycin …
Matched Products: … PATRIL 20 MG ENTERIK TABLET,14 ADET ... RANEKS 20 MG ENTERIK TABLET, 14 ADET ... RAZOGEN 20MG ENTERIK TABLET, 14 ADET …
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 (Photodynamic Therapy in Treating Patients With Lung Cancer).
Investigational
Matched Synonyms: … 3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)- …
Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Description: … By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune ... European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and ... was later approved by the FDA in 2018. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … UNAMİTY 4 MG FİLM KAPLI TABLET, 14 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 14 ADET …
Clarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug...
Approved
Matched Iupac: … (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy ... }-14-ethyl-12,13-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-7-methoxy …
Matched Description: … translation and protein assembly process. ... Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the ... Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration …
Matched Mixtures name: … Lansoprazole, Amoxicillin, and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin ... Lansoprazole, Amoxicillin and Clarithromycin …
Matched Categories: … Alimentary Tract and Metabolism ... Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins ... vonoprazan, amoxicillin and clarithromycin ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … KLAX 250 MG TABLET, 14 ADET ... CLABEL 500 MG FILM TABLET, 14 ADET ... KLAMAXIN 250 MG FILM TABLET, 14 ADET …
In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination ... with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … ANDEM 5 MG FILM TABLET, 14 ADET ... ANDEM 10 MG FILM TABLET, 14 ADET ... ANDEM 5 MG FILM TABLET, 28 ADET …
Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a...
Approved
Vet approved
Matched Description: … Salbutamol is formulated as a racemic mixture of the R- and S-isomers. ... USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and ... The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Categories: … Alcohols ... Amino Alcohols ... salbutamol and budesonide ... salbutamol and beclometasone ... salbutamol and sodium cromoglicate …
Matched Products: … SACRUSYT® LA SALBUTAMOL 100 MCG / 200 DOSIS( SIN ALCOHOL) ... SALBUTAM SR 4 MG KAPSUL, 14 ADET ... SALBUTAM SR 8 MG KAPSUL, 14 ADET …
Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Approved
Matched Description: … Zofenopril is employed as both a cardioprotective and anti-hypertensive agent. …
Matched Categories: … ACE Inhibitors and Diuretics ... zofenopril and diuretics ... zofenopril and nebivolol ... Amino Acids, Peptides, and Proteins …
Matched Products: … BIFRIL 30 MG FILM TABLET, 14 ADET ... ZOPROTEC 15 MG FILM TABLET, 14 ADET ... ZOPROTEC 30 MG FILM TABLET, 14 ADET …
Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.[A253942,L43752] The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor...
Approved
Investigational
Matched Description: … agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide]. ... [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying ... [A253917] Prior to its FDA approval, dimethyl fumarate had been used in Germany for treatment of psoriasis …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TECFIDERA 120 MG ENTERIK SERT KAPSÜL,14 ADET ... PHARON 120 MG GASTROREZİSTAN SERT KAPSÜL, 14 ADET ... TENİPRA 120 MG GASTROREZİSTAN SERT KAPSÜL, 14 ADET …
Dirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections.
Experimental
Matched Iupac: … methoxy-4,6-dimethyloxan-2-yl]oxy}-15-[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-4,16-dioxa-14
Matched Description: … to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and
Matched Categories: … Macrolides, Lincosamides and Streptogramins …
Matched Products: … DYNABAC 250 MG ENTERİK KAPLI TABLET, 14 ADET …
Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. ... [A236050] Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002. ... The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [ …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances ... 14-alpha Demethylase Inhibitors …
Matched Products: … VFEND 50 MG FILM TABLET, 14 ADET ... VORZOL 50 MG FILM TABLET,14 ADET ... VORZOL 200 MG FILM TABLET,14 ADET …
Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Description: … TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and ... be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … LUDIOMIL 75 MG TABLET, 14 ADET ... MAPROTIL 75 MG TABLET, 14 ADET …
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and
Matched Products: … ELITREX 5 MG FILM TABLET, 14 ADET ... CIPRALEX 5 MG FILM TABLET, 14 ADET ... ELITREX 10 MG FILM TABLET, 14 ADET …
Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.[A31421,L8681] Other members of this drug class include Exenatide and Liraglutide. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection...
Approved
Investigational
Matched Description: … Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection in December ... and reducing blood glucose. ... [A31421,L8681] Other members of this drug class include [Exenatide] and [Liraglutide]. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … RYBELSUS® TABLET 14MG ... RYBELSUS® 14 MG TABLETAS ... RYBELSUS 14 MG TABLET, 30 ADET …
Displaying drugs 476 - 500 of 584 in total