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Displaying drugs 51 - 75 of 2703 in total

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Colloidal oatmeal

Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Description: … Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal ... It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. ... skin irritation and itching due to rashes, eczema, poison ivy, oak, sumac, or insect bites. …
Matched Mixtures name: … Dermavive Shower and Bath Oil …
Matched Products: … BALSHI MD Calming Hemp Seed for Eczema Relief ... Skinfix Calm and Nourish Body ... Dry and Itchy Skin Relief Thayers …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and ... the activity-related kringle-2 and serine protease domains of human tPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … enhanced secretion of bile acids and lipids in the feces, patients who take complicated medication regimens ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …

Menotropins

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones ... Gonadotropins and Antigonadotropins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … MENOPUR multidose 600IU Powder and Solvent for Solution for Injection ... MENOPUR multidose 1200IU Powder and Solvent for Solution for Injection ... Menopur Powder for Injection and Solvent 75 IU …

Undecylenic acid

Undecylenate, or undecylenic acid, is an unsaturated fatty acid with a terminal double bond that is derived from castor oil. Undecylenic acid is also found naturally in the human sweat. It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones . Undecylenic acid was...
Approved
Investigational
Matched Synonyms: … Undecenoic acid ... 10-undecenoic acid ... Undecylenic acid …
Matched Name: … Undecylenic acid …
Matched Iupac: … undec-10-enoic acid …
Matched Description: … of ricinoleic acid, and has been polymerized for vinyl production [A32281]. ... relieves itching, burning, and irritation associated with the skin condition. ... undecylenate is an example of a topical antifungal agent that treats skin infections such as athlete’s foot and …
Matched Mixtures name: … Fungi Nail Toe and Foot MS ... Fungi Nail Toe and Foot MS ... Foot and Body Powder …
Matched Categories: … Fatty Acids ... undecylenic acid ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated ... undecylenic acid, combinations …
Matched Products: … Undecylenic Acid ... Fungi Nail Toe and Foot Pen ... Fungi Nail Toe and Foot …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … disinfection and surgical instruments. ... Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin ... It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … HACCP Flat Top E-2 ... Uscalrite Tec E-1 - Liq Top 0.5% ... health care personnel handwash Berry …

MM-111

MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

CLL1-CD33 compound chimeric antigen receptor T cells

Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …

Selenium Sulfide

Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Description: … is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Topco Associates ... Head and Shoulders Itch ... Walgreens Dandruff and Conditioner Cleansing and Conditioning Anti-dandruff …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Iupac: … hexaoxo-3-phenyl-icosahydropyrrolo[1,2-a]1,4,7,10,13,16-hexaazacyclooctadecan-19-yl N-(2-aminoethyl)carbamate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … ADVATE 250IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 500IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 1000IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form ... NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... powder and solvent for solution for injection 2mg …

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... 720, and a monoclonal antibody binding C-terminal to this position is used in the purification process …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …

Hydroquinone

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration ... with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and ... As a result of these concerns, hydroquinone has been banned in the EU and UK. …
Matched Mixtures name: … Top White ... Top White Skin Lightening ... CREMA CON ACIDO GLICOLICO AL 8% …
Matched Products: … Celazome Fade Shades Lightening Cream w/ Glycolic Acid ... CONDITION AND ENHANCE CLEAR Skin Bleaching and Corrector ... CONDITION AND ENHANCE BLENDER Skin Lightener and Blending …

DCVAC/OvCa

DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …

CHF5633

CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Phosphatidic Acids …

Triclosan

An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items...
Approved
Investigational
Matched Description: … sports equipment and shoes. ... An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy ... It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, …
Matched Mixtures name: … Benzocaine and Triclosan ... Benzocaine and Triclosan ... Ecosave Grapefruit and Lemongrass Soap Antibacterial Hand Soap …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives ... Fatty Acid Synthesis Inhibitors …
Matched Products: … Pumpkin Seeds Antibacterial Foaming Hand Wash ... Topco Antibacterial ... G-995 - Lot Top 0.1% …

Romilkimab

Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …

Carbidopa

Carbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does not cross the blood-brain barrier. Due to its activity, carbidopa is always administered concomitantly with levodopa. An individual formulation containing solely carbidopa was generated to treat...
Approved
Matched Synonyms: … (αS)-α-hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid ... L-3-(3,4-dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid ... (-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate …
Matched Iupac: … (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid …
Matched Description: … It potently inhibits aromatic amino acid decarboxylase (DDC) and due to its chemical properties, it does ... approved product by the FDA containing only carbidopa was developed by Amerigens Pharmaceuticals Ltd and …
Matched Mixtures name: … Carbidopa and Levodopa ... Carbidopa and Levodopa ... Carbidopa and Levodopa …
Matched Categories: … Aromatic Amino Acid Decarboxylase Inhibitors ... Aromatic L-amino Acid Decarboxylase Inhibitors …
Matched Products: … Carbidopa and Levodopa ... Carbidopa and levodopa …

Octasulfur

Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Description: … After calcium and phosphorus, it is the third most abundant mineral in the human body. ... Sulfur seems to have an antibacterial activity. It has been also used for acne. ... Sulfur is also found in garlic, onions and broccoli. …
Matched Mixtures name: … ZOLFO E POTASSIO CARBONATO NEW.FA.DEM. ... ZOLFO E POTASSIO CARBONATO NEW.FA.DEM. ... Sodium polysulthionate and folic acid …
Matched Products: … Spai-sons Acid Anti-dandruff ... Rodan and Fields Unblemish 1 Wash Acne Medicated Cleanser ... Acne Treatment Sulfur Wash Rodan and Field …

Eupatorium capillifolium pollen

Eupatorium capillifolium pollen is the pollen of the Eupatorium capillifolium plant. Eupatorium capillifolium pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Dog Fennel, Eastern Eupatorium capillifolium ... Pollens - Weeds and Garden Plants, Dog Fennel Eupatorium capillifolium …

ARGX-119

ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and …
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …

Calcium polycarbophil

Calcium polycarbophil is a stool stabilizer. Based on its chemical structure, it is a synthetic polymer of polyacrylic acid cross-linked with divinyl glycol presenting a calcium atom as a counter-ion. Polycarbophil is used to treat constipation. This drug may also be used to help relieve the symptoms of irritable bowel...
Approved
Matched Description: … It is insoluble in water, dilute acids, and dilute alkali. ... Less gas and bloating compared to psyllium laxative products, but can cause heartburn, and belly cramps ... digestive enzymes or intestinal absorption, possesses satisfactory stability, is physiologically inert, and …
Matched Categories: … Alimentary Tract and Metabolism ... Bulk-Forming Laxatives …
Matched Products: … Up and Up Fiber Therapy ... Foster and Thrive Fiber Laxative 147 ... Prodiem Bulk Fibre Therapy …

Plantago seed

Platango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements. Its potential benefit in maintaining remission in ulcerative colitis has been studied . Regardless, this agent is most predominantly used as...
Approved
Investigational
Matched Name: … Plantago seed …
Matched Description: … It is found in some laxatives for treating occasional constipation and restoring regularity in bowel ... Platango seeds refer to the seeds collected from various species of plantago trees. …
Matched Categories: … Herbs and Natural Products ... Bulk-Forming Laxatives …
Matched Products: … Psyllium Seed Blond 630mg ... Up and Up Fiber Therapy ... Bulk-forming Laxative …
Displaying drugs 51 - 75 of 2703 in total