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Displaying drugs 801 - 825 of 1083 in total

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Salts name: … Nalmefene hydrochloride ... Nalmefene hydrochloride dihydrate …
Matched Products: … Nalmefene Hydrochloride …

N-[(4-methoxyphenyl)sulfonyl]-D-alanine

Experimental
Matched Name: … N-[(4-methoxyphenyl)sulfonyl]-D-alanine …

Mexiletine

Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational
Matched Salts name: … Mexiletine hydrochloride …
Matched Products: … Mexiletine Hydrochloride ... Mexiletine hydrochloride …

Butenafine

Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes.
Approved
Matched Description: … Butenafine hydrochloride is a synthetic benzylamine antifungal agent. …
Matched Salts name: … Butenafine hydrochloride …
Matched Products: … Butenafine Hydrochloride 1% ... Butenafine Hydrochloride ... Butenafine Hydrochloride Jock Itch …

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Description: … and the absence of a chloride moiety. ... [A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction ... due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Salts name: … Olanzapine hydrochloride …
Matched Categories: … olanzapine and samidorphan ... Diazepines, Oxazepines, Thiazepines and Oxepines ... Histamine Antagonists ... Histamine H1 Antagonists ... Histamine H2 Antagonists …
Matched Products: … PROLANZ® 5 MG ... PROLANZ 10 MG ... PROLANZ ® 10MG …

PR1 leukemia peptide vaccine

PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … L-VALINE, L-VALYL-L-LEUCYL-L-GLUTAMINYL-L-.ALPHA. …
Matched Description: … PR1 leukemia peptide vaccine is under investigation in clinical trial NCT00513578 (Vaccine Therapy and …

Isoxsuprine

A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Approved
Withdrawn
Matched Description: … A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. ... It is used in the treatment of peripheral vascular disease and in premature labor. …
Matched Salts name: … Isoxsuprine hydrochloride …
Matched Products: … Isoxsuprine Hydrochloride ... ISOXSUPRINE HYDROCHLORIDE …

Epinastine

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Description: … binding to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents ... stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine …
Matched Salts name: … Epinastine hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Inhibitors ... Histamine H1 Antagonists …
Matched Products: … Epinastine Hydrochloride ... RELESTAT (EPINASTINE HYDROCHLORIDE OPHTHALMIC SOLUTION 0.5 MG/ML) ... RELESTAT (EPINASTINE HYDROCHLORIDE OPTHALMIC SOLUTION) 0.5mg/ml …

O-(N-acetyl-alpha-D-galactosaminyl)-L-serine

Experimental
Matched Name: … O-(N-acetyl-alpha-D-galactosaminyl)-L-serine …

Cysteine

A thiol-containing non-essential amino acid that is oxidized to form cystine.
Approved
Nutraceutical
Matched Salts name: … Cysteine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Cysteine Hydrochloride ... L-Cysteine Hydrochloride …

N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE

Experimental
Matched Name: … N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE …

Tirofiban

Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Synonyms: … N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine …
Matched Description: … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits …
Matched Salts name: … Tirofiban hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Tirofiban Hydrochloride ... Tirofiban hydrochloride …

Daunorubicin

A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Approved
Matched Description: … , used in treatment of leukemia and other neoplasms. ... A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others …
Matched Salts name: … Daunorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... cytarabine and daunorubicin ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Daunorubicin Hydrochloride ... Daunorubicin Hydrochloride Injection ... Daunorubicin Hydrochloride for Injection …

Buspirone

Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Description: … Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. ... receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and ... , such as generalized anxiety disorder (GAD), and relieve symptoms of anxiety. …
Matched Salts name: … Buspirone hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Buspirone Hydrochloride ... BusPIRone Hydrochloride ... Buspirone hydrochloride …

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine ... Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. …
Matched Salts name: … Vilazodone hydrochloride …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Vilazodone Hydrochloride ... Vilazodone hydrochloride …

Fluphenazine

A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Description: … Its properties and uses are generally similar to those of chlorpromazine. …
Matched Salts name: … Fluphenazine hydrochloride …
Matched Products: … Fluphenazine Hydrochloride ... Fluphenazine hydrochloride …

2-Oxy-4-Hydroxy-5-(2-Hydrazinopyridine)Phenylalanine

Experimental
Matched Name: … 2-Oxy-4-Hydroxy-5-(2-Hydrazinopyridine)Phenylalanine …

Dorzolamide

Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Description: … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA ... ) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular ... [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Salts name: … Dorzolamide hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Dorzolamide Hydrochloride ... Dorzolamide hydrochloride ... Dorzolamide Hydrochloride Ophthalmic …

MIV-711

Investigational
Matched Synonyms: … -4-yl]-4-methyl-1-oxopentan-2-yl]-4-[5-fluoro-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide hydrochloride …

Ephedrine

Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of ... norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine …
Matched Salts name: … Ephedrine hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars ... Herbs and Natural Products …
Matched Products: … EPHEDRINE HYDROCHLORIDE ... Ephedrine Hydrochloride ... Ephedrine Hydrochloride Tablets 25mg …

Trihexyphenidyl

Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders.[L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity. Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant...
Approved
Matched Description: … Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced ... [A229103] Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment …
Matched Salts name: … Trihexyphenidyl hydrochloride …
Matched Products: … Trihexyphenidyl hydrochloride ... Trihexyphenidyl Hydrochloride ... TRIHEXYPHENIDYL HYDROCHLORIDE …

Glycopyrronium

Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Description: … [L33110] They are both quaternary ammonium compounds and long acting muscarinic antagonists. ... found that glycopyrronium could also be used for reducing sweat gland,[L4755] oral,[L33140] airway, and ... L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and …
Matched Categories: … Alimentary Tract and Metabolism ... indacaterol and glycopyrronium bromide ... formoterol and glycopyrronium bromide ... glycopyrronium bromide and psycholeptics ... formoterol, glycopyrronium bromide and beclometasone …
Matched Products: … Glycate …

Sirpiglenastat

Sirpiglenastat, also known as DRP-104, is a prodrug of 6-diazo-5-oxo-L-norleucine (DON), which is a broad-acting glutamine antagonist. It is under investigation in clinical trial NCT04471415 (Study to Investigate DRP-104 in Adults With Advanced Solid Tumors).
Investigational
Matched Synonyms: … L-norleucine, n-acetyl-l-tryptophyl-6-diazo-5-oxo-, 1-methylethyl ester ... Propan-2-yl (2s)-2-((n-acetyl-l-tryptophyl)amino)-6-diazo-5-oxohexanoate …

A-16L

Investigational
Matched Synonyms: … -GLUTAMYL-L-LEUCINE ... L-LEUCINE, L-ALANYL-L-GLUTAMINYL-L-TYROSYL-L-ISOLEUCYL-L-LYSYL-L-ALANYL-L-ASPARAGINYL-L-SERYL-L-LYSYL-L-PHENYLALANYL-L-ISOLEUCYLGLYCYL-L-ISOLEUCYL-L-THREONYL-L …

Amiodarone

Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Description: … indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and ... Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved …
Matched Salts name: … Amiodarone hydrochloride …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … Amiodarone Hydrochloride ... Amiodarone hydrochloride ... AMIODARONE HYDROCHLORIDE …
Displaying drugs 801 - 825 of 1083 in total