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Displaying drugs 126 - 150 of 8596 in total

Amlodipine

Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … group of drugs called _dihydropyridine calcium channel blockers_. ... Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the …
Matched Categories: … Antianginal Agents ... Antiarrhythmic agents ... Hypotensive Agents ... Agents causing hyperkalemia ... Cardiovascular Agents …

Momelotinib

Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. It is a competitive inhibitor of JAK ATP binding. First approved by the FDA on September 15, 2023, momelotinib is used to treat myelofibrosis. Myelofibrosis (MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative hematopoietic stem cells,...
Approved
Investigational
Matched Description: … [A261566] First approved by the FDA on September 15, 2023,[L48206] momelotinib is used to treat myelofibrosis ... [L48186] Myelofibrosis (MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative …
Matched Categories: … Antineoplastic Agents ... Antineoplastic and Immunomodulating Agents …

Tedizolid phosphate

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Description: … [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist ... A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved …
Matched Categories: … Antidepressive Agents ... Anti-Bacterial Agents ... Anti-Infective Agents ... Serotonin Agents ... Immunosuppressive Agents …

Vigabatrin

Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Categories: … GABA Agents ... Neurotransmitter Agents ... Central Nervous System Agents …

Dalbavancin

Dalbavancin is a second-generation lipoglycopeptide antibiotic that was designed to improve on the natural glycopeptides currently available, such as vancomycin and teicoplanin [A4072, A4073]. Modifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin but with increased activity and once-weekly dosing [FDA Label, F2356, A4072, A4073]....
Approved
Investigational
Matched Description: … methicillin-susceptible and methicillin-resistant strains), S. pyogenes, S. agalactiae, S. dysgalactiae, the S. anginosus group …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …

Potassium hydroxide

Potassium hydroxide, also known as lye is an inorganic compound with the chemical formula KOH. Also commonly referred to as caustic potash, it is a potent base that is marketed in several forms including pellets, flakes, and powders. It is used in various chemical, industrial and manufacturing applications. Potassium hydroxide...
Approved

Mequinol

Mequinol is a phenol used in various applications. It is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons and ethyl cellulose, as an ultraviolet inhibitor, as a chemical intermediate in the manufacture of antioxidants, pharmaceuticals, plasticizers, and dyestuffs . It is found as...
Approved
Matched Categories: … Depigmenting Agents ... Protective Agents …

Birch bark extract

Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used...
Approved
Experimental
Matched Description: … wounds in patients with epidermolysis bullosa (EB), a rare group of hereditary disorders of the skin ... [L42390] Filsuvez was subsequently approved for the same indication by the US FDA in December 2023. ... [L42365,L42370] Filsuvez, one of these two formulations, is approved for the treatment of partial thickness …
Matched Categories: … Anti-Inflammatory Agents ... Anti-inflammatory Agents, Miscellaneous …

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …

Fenofibrate

Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Categories: … Hypolipidemic Agents ... Agents Causing Muscle Toxicity ... Lipid Modifying Agents ... Lipid Regulating Agents ... Lipid Modifying Agents, Plain …

Brexpiprazole

Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. Although it is structurally similar to aripiprazole, brexpiprazole has different binding affinities for dopamine and serotonin receptors. Compared...
Approved
Investigational
Matched Description: … [A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015. ... [A182186] Currently approved for the treatment of depression, schizophrenia, and agitation associated …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents Indicated for Depression ... Dopamine Agents ... Antipsychotic Agents ... Serotonin Agents …

Halothane

A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Approved
Vet approved
Matched Description: … Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents …
Matched Categories: … Hypotensive Agents ... Agents that produce hypertension ... Central Nervous System Agents …

Technetium Tc-99m red blood cells

Technetium Tc-99m red blood cells is a radiopharmaceutical diagnostic agent that is intravenously administered to be used in blood pool imaging, including cardiac first pass and gated equilibrium imaging and for detection of sites of gastrointestinal bleeding. It is clinically useful in early detection and localization of bleeding sites, and...
Approved

Meradimate

Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Description: … [T200] It is currently required to be named as meradimate in all FDA approved OTC products. ... Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products …
Matched Categories: … Sunscreen Agents …

Abacavir

Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Categories: … Anti-HIV Agents ... Antiviral Agents ... Anti-Infective Agents ... Anti-Retroviral Agents …

Amcinonide

Amcinonide is a corticosteroid.
Approved
Matched Categories: … Corticosteroids, Potent (Group III) ... Anti-Inflammatory Agents ... Immunosuppressive Agents ... Hyperglycemia-Associated Agents …

Gepirone

Gepirone, an azapirone, is a pharmacologic analog of buspirone that acts selectively on the pre- and post-synaptic 5HT1A receptors. Although earlier clinical trials showed promising results for gepirone, its formulation as an immediate-release tablet necessitates frequent administration due to the short half-lives. It was not until an extended-release formulation of...
Approved
Investigational
Matched Description: … [A261670,A261675,A182315] Gepirone was approved by the FDA on September 28, 2023, under the brand …
Matched Categories: … Antidepressive Agents ... Anti-Anxiety Agents ... Serotonin Agents ... Tranquilizing Agents ... Neurotransmitter Agents …

Tinidazole

A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
Approved
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Antiparasitic Agents ... Antitrichomonal Agents …

Romidepsin

Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment of cutaneous T-cell lymphoma (CTCL) in patients who have received at least one prior systemic therapy.
Approved
Investigational
Matched Description: … Romidepsin is a selective inhibitor of histone deacetylase, approved in the US in 2009 for the treatment …
Matched Categories: … Antineoplastic Agents ... QTc Prolonging Agents ... Highest Risk QTc-Prolonging Agents ... Antineoplastic and Immunomodulating Agents …

Alpha-1-proteinase inhibitor

Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Categories: … Antifibrinolytic Agents …

Nitrazepam

A benzodiazepine derivative used as an anticonvulsant and hypnotic.
Approved
Matched Categories: … GABA Agents ... Anti-Anxiety Agents ... Tranquilizing Agents ... Neurotransmitter Agents ... Central Nervous System Agents …

Sucralfate

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Description: … It was approved by the FDA 1982 in tablet form, and in 1994 for the suspension form [L6073, L6076]. ... considered a _cytoprotective agent_, protecting cells in the gastrointestinal tract from damage caused by agents …
Matched Categories: … Anti-Ulcer Agents ... Gastrointestinal Agents …

Lidocaine

Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched Categories: … Antiarrhythmic agents ... Cardiovascular Agents ... Sensory System Agents ... Central Nervous System Agents ... Agents that reduce seizure threshold …

Silver sulfadiazine

Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
Approved
Vet approved
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Anti-Infective Agents, Local …

Olipudase alfa

Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … [A251590] It was later approved by the European Commission on June 28, 2022 [L42740] and by the FDA on …
Displaying drugs 126 - 150 of 8596 in total