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Displaying drugs 201 - 225 of 15512 in total

Sertraline

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Synonyms: … (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine …
Matched Iupac: … (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine …
Matched Description: … is similar to drugs such as [Citalopram] and [Fluoxetine]. ... popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and ... classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and …

Piroxicam

A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid …
Matched Iupac: … 4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1lambda6,2-benzothiazine-3-carboxamide …
Matched Description: … osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. ... non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Menotropins

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Menopur Powder for Injection and Solvent 75 IU ... Menopur Powder and Solvent For Solution for Injection 75iu ... MENOPUR multidose 600IU Powder and Solvent for Solution for Injection …

Selenium Sulfide

Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Description: … is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Head and Shoulders Itch ... Walgreens Dandruff and Conditioner Cleansing and Conditioning Anti-dandruff ... Head and Shoulders Clinical Strength …

Cefotaxime

Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Synonyms: … aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... -thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … -thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5 …
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Products: … Cefotaxime and Dextrose …

Fenoterol

Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
Approved
Investigational
Matched Synonyms: … 3,5-dihydroxy-α-(((p-hydroxy-α-methylphenethyl)amino)methyl)benzyl alcohol ... 5-{1-Hydroxy-2-[2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-benzene-1,3-diol …
Matched Description: … Fenoterol is an adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic. …
Matched Categories: … fenoterol and ipratropium bromide ... Genito Urinary System and Sex Hormones …

Ramipril

Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Synonyms: … 2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid …
Matched Iupac: … [(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid …
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Categories: … simvastatin, acetylsalicylic acid and ramipril ... atorvastatin, acetylsalicylic acid and ramipril ... ACE Inhibitors and Diuretics ... ramipril and diuretics ... ramipril and felodipine …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … ADVATE 250IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 500IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 1000IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … During secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …

Aluminum chlorohydrate

Aluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. It is included up to 25% in over-the-counter hygiene products as an active antiperspirant agent. The primary site of action of aluminum chlorohydrate is at the level of the stratum corneum layer, which is relatively near...
Approved
Matched Categories: … Astringents and Deodorants ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … Soft and Dri Cool and Clean ... Suave Sweet Pea and Violet Antiperspirant and Deodorant ... G and H Protect Deodorant and Antiperspirant Roll On …

Dobutamine

A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Synonyms: … 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol …
Matched Categories: … Adrenergic and Dopaminergic Agents …

Alprostadil

Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Synonyms: … 11α,15α-dihydroxy-9-oxo-13-trans-prostenoic acid ... (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid …
Matched Iupac: … 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid …
Matched Description: … intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and ... This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle …
Matched Categories: … Genito Urinary System and Sex Hormones …

Lumacaftor

Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... Approved for use by the Food and Drug Administration in July 2015 and by Health Canada in January 2016 ... and trafficking of mature protein to the cell surface. …
Matched Categories: … ivacaftor and lumacaftor …

Benzylparaben

Benzylparaben is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … p-Hydroxybenzoic acid benzyl ester …

Dexfenfluramine

Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss. However, following multiple concerns about the cardiovascular side-effects of the drug, such approval was withdrawn.
Approved
Illicit
Investigational
Withdrawn
Matched Synonyms: … d-N-ethyl-α-methyl-m-trifluoromethylphenethylamine …
Matched Categories: … Alimentary Tract and Metabolism …

Terfenadine

In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Approved
Withdrawn
Matched Synonyms: … (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-ol …

Pyrazinamide

A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Matched Synonyms: … Pyrazinoic acid amide …
Matched Categories: … rifampicin, pyrazinamide and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …

Dexamethasone acetate

Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as hydrocortisone and prednisolone. Dexamethasone acetate has largely been replaced by dexamethasone phosphate and...
Approved
Investigational
Vet approved
Matched Synonyms: … 16alpha-Methyl-9alpha-fluoroprednisolone 21-acetate …
Matched Description: … one-third in patients on oxygen therapy and mechanical ventilation, respectively. ... previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and ... [A188724] Dexamethasone acetate has largely been replaced by [dexamethasone] phosphate and continues …

Bromhexine

Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Synonyms: … N-cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine …
Matched Iupac: … 2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline …
Matched Description: … and reducing cough. ... prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs. ... It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many …
Matched Categories: … Cough and Cold Preparations …

Venetoclax

Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Synonyms: … 4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro ... -4-{[(oxan-4-yl)methyl]amino}benzene-1-sulfonyl)-2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]benzamide ... 4-{4-[(4'-chloro-5,5-dimethyl[3,4,5,6-tetrahydro[1,1'-biphenyl]]-2-yl)methyl]piperazin-1-yl}-N-(3-nitro …
Matched Iupac: … 4-yl)methyl]amino}benzenesulfonyl)-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzamide ... 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-(3-nitro-4-{[(oxan- …
Matched Description: … Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Sildenafil

In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Synonyms: … 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl) …
Matched Iupac: … 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1H,4H,7H-pyrazolo[4,3-d]pyrimidin …
Matched Description: … it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows …

Chenopodium album pollen

Chenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Lamb Quarters Chenopodium album ... Pollens - Weeds and Garden Plants, Lambs Quarters Chenopodium album …

Enzacamene

Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Synonyms: … Methyl benzylidene camphor …
Matched Description: … Its tradenames include Eusolex 6300 (Merck) and Parsol 5000 (DSM). ... Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic ... human reproductive system as an endocrine disruptor are being investigated, its use in over-the-counter and …
Matched Mixtures name: … Natural Sun AQ Body and Family Mild Sun Milk ... Outback 2-in-1 Insect Repellent and Protective Sunscreen ... mesoestetic moisturizing sun protection BROAD SPECTRUM FOR NORMAL AND DRY SKINS …

Calcium glycerophosphate

Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Synonyms: … β-glycerophosphoric acid calcium salt …
Matched Description: … Calcium glycerophosphate is a [DB01373] salt of glycerophosphoric acid that forms a white, fine, slightly ... The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. ... phosphate levels and direct interaction with dental mineral [A27153]. …
Matched Mixtures name: … Somarexin and C 1000 ... NUTROPLEX LIQUID WITH IRON AND LYSINE …

Mezlocillin

Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Matched Synonyms: … 6β-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid ... oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … carbonyl)amino]-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and …
Displaying drugs 201 - 225 of 15512 in total