Displaying drugs 1 - 25 of 106 in total
Recombinant stabilized RSV A prefusion F antigen
Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Synonyms: … RSV subgroup A stabilized prefusion F protein …
Matched Name: … Recombinant stabilized RSV A prefusion F antigen …
Matched Description: … Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial ... The vaccine comprises two antigens - the other being [recombinant stabilized RSV A prefusion F antigen ... ] - which have been expressed in Chinese hamster ovary cell lines and then purified and lyophilized. …
Matched Categories: … Respiratory syncytial virus (RSV) vaccines …
Matched Name: … Recombinant stabilized RSV A prefusion F antigen …
Matched Description: … Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial ... The vaccine comprises two antigens - the other being [recombinant stabilized RSV A prefusion F antigen ... ] - which have been expressed in Chinese hamster ovary cell lines and then purified and lyophilized. …
Matched Categories: … Respiratory syncytial virus (RSV) vaccines …
Recombinant stabilized RSV B prefusion F antigen
Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Synonyms: … RSV subgroup B stabilized prefusion F protein …
Matched Name: … Recombinant stabilized RSV B prefusion F antigen …
Matched Description: … Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial ... The vaccine comprises two antigens - the other being [recombinant stabilized RSV A prefusion F antigen ... ] - which have been expressed in Chinese hamster ovary cell lines and then purified and lyophilized. …
Matched Categories: … Respiratory syncytial virus (RSV) vaccines …
Matched Name: … Recombinant stabilized RSV B prefusion F antigen …
Matched Description: … Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial ... The vaccine comprises two antigens - the other being [recombinant stabilized RSV A prefusion F antigen ... ] - which have been expressed in Chinese hamster ovary cell lines and then purified and lyophilized. …
Matched Categories: … Respiratory syncytial virus (RSV) vaccines …
Influenza A virus A/Victoria/361/2011 (H3N2) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … influenza A virus A/Victoria/361/2011 (H3N2) antigen …
Matched Name: … Influenza A virus A/Victoria/361/2011 (H3N2) recombinant hemagglutinin antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen …
Matched Name: … Influenza A virus A/Victoria/361/2011 (H3N2) recombinant hemagglutinin antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen …
Neisseria meningitidis serogroup b fhbp fusion protein antigen
Approved
Matched Synonyms: … Neisseria meningitidis serogroup B recombinant FHBP fusion protein antigen …
Matched Name: … Neisseria meningitidis serogroup b fhbp fusion protein antigen …
Matched Name: … Neisseria meningitidis serogroup b fhbp fusion protein antigen …
Influenza A virus A/Wisconsin/588/2019 (H1N1) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Wisconsin/588/2019 (H1N1) recombinant hemagglutinin antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen …
Matched Categories: … Recombinant influenza vaccines …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen …
Matched Categories: … Recombinant influenza vaccines …
Influenza A virus A/Tasmania/503/2020 (H3N2) recombinant hemagglutinin antigen
Approved
Matched Name: … Influenza A virus A/Tasmania/503/2020 (H3N2) recombinant hemagglutinin antigen …
Matched Categories: … Recombinant influenza vaccines …
Matched Categories: … Recombinant influenza vaccines …
Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen …
Influenza A virus A/Kansas/14/2017 (H3N2) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Kansas/14/2017 (H3N2) recombinant hemagglutinin antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen …
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... defence includes the production of humoral immunity through the development of antibodies (through memory B ... parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen …
Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen
Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine for intramuscular injection indicated for the active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated...
Approved
Matched Name: … Neisseria meningitidis serogroup B recombinant LP2086 A05 protein variant antigen …
Matched Description: … Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine ... and one from subfamily B (A05 and B01, respectively). ... It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated …
Matched Description: … Neisseria meningitidis serogroup B recombinant lp2086 a05 protein variant antigen is a sterile vaccine ... and one from subfamily B (A05 and B01, respectively). ... It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated …
Respiratory syncytial virus vaccine, adjuvanted
Arexvy (respiratory syncytial virus vaccine, adjuvanted) is an adjuvanted vaccine developed by GlaxoSmithKline Biologicals. It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with the accompanying vial of AS01E adjuvant as the adjuvant...
Approved
Matched Synonyms: … RECOMBINANT RESPIRATORY SYNCYTIAL VIRUS PRE-FUSION F PROTEIN ... RESPIRATORY SYNCYTIAL VIRUS PREFUSION F PROTEIN (RSVPREF3) …
Matched Description: … It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized ... in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with ... immunization against lower respiratory tract disease (LRTD) as the first respiratory syncytial virus (RSV …
Matched Categories: … Respiratory syncytial virus (RSV) vaccines …
Matched Description: … It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized ... in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with ... immunization against lower respiratory tract disease (LRTD) as the first respiratory syncytial virus (RSV …
Matched Categories: … Respiratory syncytial virus (RSV) vaccines …
Human papillomavirus type 33 L1 capsid protein antigen
Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 33. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … Recombinant human papillomavirus type 33 L1 protein …
Matched Name: … Human papillomavirus type 33 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 33 which are produced by separate fermentations in recombinant …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Name: … Human papillomavirus type 33 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 33 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular ... *Saccharomyces cerevisiae* and self-assembled into VLPs. ... VLPs) of the major capsid (L1) protein of HPV Type 33 which are produced by separate fermentations in recombinant …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 6 L1 capsid protein antigen
Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Synonyms: … Recombinant human papillomavirus type 6 L1 protein …
Matched Name: … Human papillomavirus type 6 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Name: … Human papillomavirus type 6 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 6 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Human papillomavirus type 16 L1 capsid protein antigen
Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Investigational
Matched Synonyms: … Recombinant human papillomavirus type 16 L1 protein …
Matched Name: … Human papillomavirus type 16 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Human papillomavirus type 16 L1 capsid protein antigen …
Matched Description: … Human papillomavirus type 16 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... 18, which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and self-assembled ... by Human Papillomavirus (HPV) types 6, 11, 16 and 18. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Influenza A Virus A/Victoria/4897/2022 IVR-238 (H1N1) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A Virus A/Victoria/4897/2022 IVR-238 (H1N1) antigen (formaldehyde inactivated) …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Influenza A virus A/Darwin/9/2021 IVR-228 (H3N2) antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Darwin/9/2021 IVR-228 (H3N2) antigen (UV, formaldehyde inactivated) …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Influenza A virus A/Georgia/12/2022 CVR-167 (H1N1) Antigen (MDCK cell derived, propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that helps to protect against infection from influenza viruses. These vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which results in...
Approved
Matched Name: … Influenza A virus A/Georgia/12/2022 CVR-167 (H1N1) Antigen (MDCK cell derived, propiolactone inactivated …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Matched Description: … Recombinant influenza vaccines are produced by synthesizing recombinant influenza hemagglutinin antigen ... in a laboratory and do not require the use of candidate viruses or egg-based manufacturing processes ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Interferon gamma-1b
Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography.
The sequence displayed is a cDNA sequence which...
Approved
Investigational
Matched Synonyms: … Interferon gamma 1-b ... Interferon gamma-1b, recombinant …
Matched Description: … et. al. and not specifically interferon gamma 1b. ... Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium ... The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … et. al. and not specifically interferon gamma 1b. ... Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium ... The sequence displayed is a cDNA sequence which codes for human interferon gamma, as described by Gray …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Efanesoctocog alfa
Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding episodes in patients with hemophilia A. The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl …
Matched Description: … Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and ... routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
Matched Description: … Efanesoctocog alfa (BIVV001) is a recombinant factor VIII (FVIII) analogue fusion protein used for the ... To extend the half-life of FVIII, efanesoctocog alfa is fused to dimeric Fc, a D'D3 domain of VWF, and ... routine prophylaxis, perioperative management of bleeding and on-demand treatment and control of bleeding …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Recombinant Proteins ... Recombinant Fusion Proteins …
Raxibacumab
Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
Approved
Matched Description: … Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. ... Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of ... B. anthracis toxin. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Anthrax Protective Antigen-directed Antibody ... Anthrax Protective Antigen-directed Antibody Interactions …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Anthrax Protective Antigen-directed Antibody ... Anthrax Protective Antigen-directed Antibody Interactions …
Bamlanivimab
Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from one of the first blood samples in the United States from a patient who recovered from COVID-19.[A224039, L15311, L15316] Bamlanivimab is a neutralizing IgG1κ mAb directed against the SARS-CoV-2 spike (S) protein, which is described to...
Approved
Investigational
Matched Description: … one of the first blood samples in the United States from a patient who recovered from COVID-19. ... Bamlanivimab (LY-CoV555, also known as LY3819253), is a synthetic monoclonal antibody (mAb) derived from ... [A224039, L15311, L15316] Bamlanivimab is a neutralizing IgG1κ mAb directed against the SARS-CoV-2 spike …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Rituximab
Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … CD20 antigen found on the surface of normal and malignant B lymphocytes. ... FDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however ... , has now been approved for a variety of conditions [FDA label]. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Amino Acids, Peptides, and Proteins ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Belimumab
Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Description: … Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte ... stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. ... It is produced by recombinant DNA technology in a murine cell (NS0) expression system. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Decreased B Lymphocyte Activation ... B Lymphocyte Stimulator-specific Inhibitor ... B Lymphocyte Stimulator-directed Antibody Interactions …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Decreased B Lymphocyte Activation ... B Lymphocyte Stimulator-specific Inhibitor ... B Lymphocyte Stimulator-directed Antibody Interactions …
Tebentafusp
Tebentafusp is a gp100 peptide-HLA-directed CD3 T cell engager. It is a bispecific, fusion protein and first-in-class drug of immune-mobilizing monoclonal T cell receptors against cancer (ImmTACs), a recently developed cancer immunotherapy with a novel mechanism of action. ImmTACs bind to target cancer cells that express a specific antigen of...
Approved
Investigational
Matched Description: … ImmTACs bind to target cancer cells that express a specific antigen of interest and recruit cytotoxic ... [L39995] It is a bispecific, fusion protein and first-in-class drug of immune-mobilizing monoclonal T ... [A244815,A244910]
Uveal melanoma is a rare ocular tumour with often poor prognosis and limited treatment …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Recombinant Proteins ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Alemtuzumab
Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Matched Description: … It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the ... [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic ... The dose of alemtuzumab used for B-CLL is much higher than that for MS, and also at more frequent dosing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Tafasitamab
Tafasitamab is a humanized, CD19-directed cytolytic monoclonal antibody intended for the treatment of B-cell malignancies. It is produced using recombinant DNA technology in Chinese hamster ovary cells, and contains an IgG1/2 hybrid Fc-domain which has been modified with 2 amino acid substitutions to enhance its cytotoxicity relative to non-engineered anti-CD19...
Approved
Investigational
Matched Description: … [L15302] It is produced using recombinant DNA technology in Chinese hamster ovary cells, and contains ... Tafasatimab is designed to bind to and block the activity of the CD19 surface antigen, which ultimately ... appears to play a role in enhancing B-cell receptor signaling. …
Matched Categories: … Lymphoma, B-Cell ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … Lymphoma, B-Cell ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Displaying drugs 1 - 25 of 106 in total