Spironolactone.

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Patibandla S, Heaton J, Kyaw H

Spironolactone.

PubMed ID

32119308 [ View in PubMed

]

Abstract

Spironolactone is a medication used in the management and treatment of hypertension and heart failure with some indications aside from cardiovascular disease. It is in the mineralocorticoid receptor antagonist class of drugs. This activity reviews the indications, action, and contraindications for spironolactone as a valuable agent in the management of cardiovascular diseases and other disorders when applicable.

DrugBank Data that Cites this Article

Drugs

Spironolactone

Drug Targets

Drug	Target	Kind	Organism	Pharmacological Action	Actions
Spironolactone	Androgen receptor	Protein	Humans	Unknown	Antagonist	Details

Drug Interactions

Drugs	Interaction
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Spironolactone Celiprolol	The risk or severity of hyperkalemia can be increased when Celiprolol is combined with Spironolactone.
Spironolactone Nebivolol	The risk or severity of hyperkalemia can be increased when Nebivolol is combined with Spironolactone.
Spironolactone Nylidrin	The risk or severity of hyperkalemia can be increased when Nylidrin is combined with Spironolactone.
Spironolactone Anisodamine	The risk or severity of hyperkalemia can be increased when Anisodamine is combined with Spironolactone.
Spironolactone Nicorandil	The risk or severity of hyperkalemia can be increased when Nicorandil is combined with Spironolactone.