You are using an unsupported browser. Please upgrade your browser to a newer version to get the best experience on DrugBank.
Identification
NamePotassium Chloride
Accession NumberDB00761  (APRD01322)
TypeSmall Molecule
GroupsApproved, Withdrawn
Description

A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.

Structure
Thumb
Synonyms
SynonymLanguageCode
[KCl]Not AvailableNot Available
Chlorid draselnyCzechNot Available
Chloride of potashNot AvailableNot Available
KaliumchloridNot AvailableNot Available
Kaon-CL 10Not AvailableNot Available
KClNot AvailableNot Available
Klor-CONNot AvailableNot Available
KlotrixNot AvailableNot Available
Monopotassium chlorideNot AvailableNot Available
Muriate of potashNot AvailableNot Available
SylviteNot AvailableNot Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
K-tabtablet, film coated, extended release1500 mgoralAbb Vie Inc.1980-06-09Not AvailableUs
K-tabtablet, film coated, extended release600 mgoralAbb Vie Inc.1980-06-09Not AvailableUs
K-tabtablet, film coated, extended release750 mgoralAbb Vie Inc.1980-06-09Not AvailableUs
Klor-contablet, film coated, extended release600 mgoralUpsher Smith Laboratories, Inc.1986-04-17Not AvailableUs
Klor-contablet, film coated, extended release750 mgoralUpsher Smith Laboratories, Inc.1986-04-17Not AvailableUs
Potassium Chloridetablet, extended release600 mgoralUpsher Smith Laboratories, Inc.1986-04-17Not AvailableUs
Potassium Chloridetablet, extended release750 mgoralUpsher Smith Laboratories, Inc.1986-04-17Not AvailableUs
Potassium Chloridetablet, extended release600 mgoralUpsher Smith Laboratories, Inc.1986-04-17Not AvailableUs
Potassium Chloridetablet, extended release750 mgoralUpsher Smith Laboratories, Inc.1986-04-17Not AvailableUs
Potassium Chlorideinjection, solution29.8 g/1000mLintravenousBaxter Healthcare Corporation1989-12-26Not AvailableUs
Potassium Chlorideinjection, solution14.9 g/1000mLintravenousBaxter Healthcare Corporation1989-12-26Not AvailableUs
Potassium Chlorideinjection, solution22.4 g/1000mLintravenousBaxter Healthcare Corporation1989-12-26Not AvailableUs
Potassium Chlorideinjection, solution7.46 g/1000mLintravenousBaxter Healthcare Corporation1989-12-26Not AvailableUs
Potassium Chlorideinjection, solution10 meq/100mLintravenousHospira, Inc.1992-11-30Not AvailableUs
Potassium Chlorideinjection, solution200 meq/1000mLintravenousHospira, Inc.1992-11-30Not AvailableUs
Potassium Chlorideinjection, solution30 meq/100mLintravenousHospira, Inc.1992-11-30Not AvailableUs
Potassium Chlorideinjection, solution400 meq/1000mLintravenousHospira, Inc.1992-11-30Not AvailableUs
Klor-contablet, film coated, extended release750 mgoralLiberty Pharmaceuticals, Inc.1986-04-17Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-10-25Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2010-10-25Not AvailableUs
Potassium Chloridetablet, film coated, extended release600 mgoralSandoz Inc.1986-04-17Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralSandoz Inc.1986-04-17Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralREMEDYREPACK INC.2013-02-28Not AvailableUs
Klor-contablet, film coated, extended release750 mgoralREMEDYREPACK INC.2013-03-18Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralAidarex Pharmaceuticals LLC1986-04-17Not AvailableUs
K-tabtablet, film coated, extended release750 mgoralAphena Pharma Solutions Tennessee, Llc1980-06-09Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralREMEDYREPACK INC.2013-05-21Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralREMEDYREPACK INC.2012-09-11Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralLake Erie Medical DBA Quality Care Products LLC2011-02-22Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralNesher Pharmaceuticals (USA) LLC2010-10-25Not AvailableUs
Potassium Chloridecapsule, extended release600 mgoralNesher Pharmaceuticals (USA) LLC2010-10-25Not AvailableUs
Potassium Chloridetablet, extended release750 mgoralREMEDYREPACK INC.2012-09-21Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralREMEDYREPACK INC.2013-05-28Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralREMEDYREPACK INC.2013-11-12Not AvailableUs
K-tabtablet, film coated, extended release750 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Klor-con Extended-releasetablet, extended release600 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Klor-con Extended-releasetablet, extended release750 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Potassium Chloridetablet, film coated, extended release600 mgoralA S Medication Solutions Llc1986-04-17Not AvailableUs
Potassium Chloridetablet, film coated, extended release600 mgoralPhysicians Total Care, Inc.1996-10-01Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralCardinal Health1986-04-17Not AvailableUs
Klor-contablet, film coated, extended release750 mgoralCardinal Health1986-04-17Not AvailableUs
Klor-contablet, film coated, extended release600 mgoralCardinal Health1986-04-17Not AvailableUs
Klor-contablet, film coated, extended release600 mgoralPd Rx Pharmaceuticals, Inc.1986-04-17Not AvailableUs
Potassium Chloridetablet, film coated, extended release600 mgoralClinical Solutions Wholesale1986-04-17Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralClinical Solutions Wholesale1986-04-17Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralSt Marys Medical Park Pharmacy2013-05-15Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralSt Marys Medical Park Pharmacy2014-08-20Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralREMEDYREPACK INC.2014-08-05Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralDIRECT RX2014-01-01Not AvailableUs
Potassium Chloridetablet, film coated, extended release20 meqoralDIRECT RX2014-01-01Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralbryant ranch prepack1986-04-17Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralbryant ranch prepack2011-02-22Not AvailableUs
Micro-k 10 Extencapscapsule, extended release750 mgoralTher Rx Corporation2009-08-01Not AvailableUs
Micro-k Extencapscapsule, extended release600 mgoralTher Rx Corporation2009-08-01Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralTYA Pharmaceuticals2011-02-22Not AvailableUs
Potassium Chloridesolution20 meq/15mLoralLehigh Valley Technologies, Inc.2015-02-15Not AvailableUs
Potassium Chloridesolution40 meq/15mLoralLehigh Valley Technologies, Inc.2015-02-15Not AvailableUs
Klor-contablet, film coated, extended release600 mgoralSandoz Inc.2014-09-01Not AvailableUs
Klor-contablet, film coated, extended release750 mgoralSandoz Inc.2014-09-01Not AvailableUs
Klor-con Extended-releasetablet, extended release750 mgoralContract Pharmacy Services Pa1986-04-17Not AvailableUs
Klor-contablet, film coated, extended release600 mgoralAphena Pharma Solutions Tennessee, Llc1986-04-17Not AvailableUs
Klor-contablet, film coated, extended release750 mgoralAphena Pharma Solutions Tennessee, Llc1986-04-17Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralAmerican Health Packaging2012-07-02Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralAmerican Health Packaging2011-09-13Not AvailableUs
Potassium Chloridetablet, film coated, extended release1500 mgoralZydus Pharmaceuticals USA Inc2014-01-16Not AvailableUs
Potassium Chloridetablet, film coated, extended release750 mgoralZydus Pharmaceuticals USA Inc2011-02-22Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralZydus Pharmaceuticals (USA) Inc.2010-10-25Not AvailableUs
Potassium Chloridecapsule, extended release600 mgoralZydus Pharmaceuticals (USA) Inc.2010-10-25Not AvailableUs
Potassium Chloridetablet, film coated, extended release600 mgoralZydus Pharmaceuticals USA Inc2014-01-16Not AvailableUs
Klor-contablet, film coated, extended release600 mgoralLegacy Pharmaceutical Packaging1986-04-17Not AvailableUs
Klor-contablet, film coated, extended release750 mgoralLegacy Pharmaceutical Packaging1986-04-17Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralMc Kesson Contract Packaging2013-04-15Not AvailableUs
Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Klor-con Mtablet, extended release750 mgoralUpsher Smith Laboratories, Inc.2011-01-18Not AvailableUs
Klor-con Mtablet, extended release1500 mgoralUpsher Smith Laboratories, Inc.2011-01-18Not AvailableUs
Klor-con Mtablet, extended release1125 mgoralUpsher Smith Laboratories, Inc.2011-01-18Not AvailableUs
Potassium Chlorideinjection, solution, concentrate14.9 g/100mLparenteralB. Braun Medical Inc.1978-03-21Not AvailableUs
Potassium Chloridetablet, film coated, extended release8 meqoralMylan Pharmaceuticals Inc.2014-08-21Not AvailableUs
Potassium Chloridetablet, film coated, extended release10 meqoralMylan Pharmaceuticals Inc.2014-08-21Not AvailableUs
Potassium Chlorideinjection, solution, concentrate149 mg/mLintravenousHospira, Inc.1972-03-16Not AvailableUs
Potassium Chlorideinjection, solution, concentrate149 mg/mLintravenousHospira, Inc.1972-03-16Not AvailableUs
Potassium Chlorideinjection, solution, concentrate149 mg/mLintravenousHospira, Inc.1972-03-16Not AvailableUs
Potassium Chlorideinjection, solution, concentrate149 mg/mLintravenousHospira, Inc.1972-03-16Not AvailableUs
Potassium Chlorideinjection, solution, concentrate149 mg/mLintravenousHospira, Inc.1972-03-16Not AvailableUs
Potassium Chloridecapsule, extended release600 mgoralPaddock Laboratories, LLC2011-06-03Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralPaddock Laboratories, LLC2011-06-03Not AvailableUs
Klor Con Mtablet, extended release1500 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs1998-11-20Not AvailableUs
Klor Con Mtablet, extended release750 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs1998-11-20Not AvailableUs
Klor-con Mtablet, extended release750 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-09-01Not AvailableUs
Klor-con Mtablet, extended release1500 mgoralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-09-01Not AvailableUs
Potassium Chloridetablet, film coated, extended release10 meqoralNcs Health Care Of Ky, Inc Dba Vangard Labs2014-08-21Not AvailableUs
Potassium Chloridetablet, extended release1500 mgoralSandoz Inc1998-11-20Not AvailableUs
Potassium Chloridetablet, extended release750 mgoralSandoz Inc1998-11-20Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralMajor Pharmaceuticals2009-08-25Not AvailableUs
Potassium Chloride Extended-Releasecapsule, extended release8 meqoralPar Pharmaceutical, Inc.2013-12-26Not AvailableUs
Potassium Chloride Extended-Releasecapsule, extended release10 meqoralPar Pharmaceutical, Inc.2013-12-26Not AvailableUs
Klor-con M10tablet, extended release10 meqoralApace Packaging LLC2000-08-09Not AvailableUs
Klor-con M20tablet, extended release20 meqoralApace Packaging LLC2000-08-09Not AvailableUs
Potassium Chloridetablet, extended release10 meqoralRebel Distributors Corp2002-04-10Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralRebel Distributors Corp2002-04-10Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralREMEDYREPACK INC.2013-10-07Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralAidarex Pharmaceuticals LLC2002-04-10Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralAv Kare, Inc.2014-05-07Not AvailableUs
Potassium Chloridecapsule, extended release8 meqoralAv Kare, Inc.2013-03-05Not AvailableUs
Potassium Chloridecapsule, extended release10 meqoralAv Kare, Inc.2013-03-05Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralAphena Pharma Solutions Tennessee, Llc2004-08-18Not AvailableUs
Klor-con Mtablet, extended release750 mgoralAphena Pharma Solutions Tennessee, Llc2011-01-18Not AvailableUs
Potassium Chloridetablet, extended release1500 mgoralSafecor Health, LLC2014-09-30Not AvailableUs
Potassium Chloridetablet, extended release750 mgoralSafecor Health, LLC2014-09-30Not AvailableUs
Klor-con Mtablet, extended release1500 mgoralREMEDYREPACK INC.2011-09-26Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralUnit Dose Services2004-08-18Not AvailableUs
Klor-con Mtablet, extended release1500 mgoralUnit Dose Services1998-11-20Not AvailableUs
Potassium Chloride ERtablet20 meqoralNorthwind Pharmaceuticals, LLC2014-10-22Not AvailableUs
Potassium Chloridetablet, extended release1500 mgoralREMEDYREPACK INC.2013-09-27Not AvailableUs
Potassium Chlorideinjection2 meq/mLintravenousGeneral Injectables & Vaccines, Inc2010-08-01Not AvailableUs
Potassium Chlorideinjection, solution2 meq/mLintravenousGeneral Injectables & Vaccines, Inc2010-08-01Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralAmneal Pharmaceuticals of New York, LLC2013-02-22Not AvailableUs
Potassium Chloridetablet, extended release1500 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Potassium Chloridetablet, extended release600 mgoralState of Florida DOH Central Pharmacy2009-07-01Not AvailableUs
Potassium Chlorideinjection, solution, concentrate149 mg/mLintravenousPhysicians Total Care, Inc.2007-03-16Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralPhysicians Total Care, Inc.1996-04-11Not AvailableUs
Potassium Chloridetablet, extended release10 meqoralPhysicians Total Care, Inc.2004-12-17Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralPhysicians Total Care, Inc.2002-04-19Not AvailableUs
Klor-con Mtablet, extended release1500 mgoralCardinal Health2014-09-01Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralCardinal Health2009-08-10Not AvailableUs
Potassium Chloridetablet, extended release1500 mgoralCardinal Health2010-01-21Not AvailableUs
Potassium Chlorideinjection149 mg/mLintravenousCardinal Health1972-03-16Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralCardinal Health2009-08-25Not AvailableUs
Potassium Chloridetablet, extended release1500 mgoralCardinal Health1998-11-20Not AvailableUs
Potassium Chloridetablet, extended release750 mgoralCardinal Health1998-11-20Not AvailableUs
Klor-con M20tablet, extended release1500 mgoralCardinal Health2011-01-18Not AvailableUs
Klor-con M10tablet, extended release750 mgoralCardinal Health2011-01-18Not AvailableUs
Klor-con Mtablet, extended release10 meqoralCardinal Health2011-01-18Not AvailableUs
Potassium Chlorideinjection149 mg/mLintravenousCardinal Health1972-03-16Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralPd Rx Pharmaceuticals, Inc.2008-08-25Not AvailableUs
Potassium Chloridetablet, extended release10 meqoralPd Rx Pharmaceuticals, Inc.2002-04-10Not AvailableUs
Klor-con Mtablet, extended release20 meqoralPd Rx Pharmaceuticals, Inc.2011-01-18Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralPd Rx Pharmaceuticals, Inc.2004-08-18Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralClinical Solutions Wholesale2004-08-18Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralSt Marys Medical Park Pharmacy .2013-05-16Not AvailableUs
Potassium Chloridecapsule, extended release8 meqoralWatson Pharma, Inc.2008-08-25Not AvailableUs
Potassium Chloridecapsule, extended release10 meqoralWatson Pharma, Inc.2008-08-25Not AvailableUs
Potassium Chloridetablet, extended release10 meqoralWatson Pharma, Inc.2002-04-10Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralWatson Pharma, Inc.2002-04-10Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralWatson Pharma, Inc.2004-08-18Not AvailableUs
Potassium Chlorideinjection, solution, concentrate2 meq/mLintravenousAPP Pharmaceuticals, LLC1999-09-27Not AvailableUs
Potassium Chlorideinjection, solution, concentrate2 meq/mLintravenousAPP Pharmaceuticals, LLC2000-09-05Not AvailableUs
Potassium Chloridetablet, extended release750 mgoralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2009-08-03Not AvailableUs
Potassium Chloridetablet, extended release1500 mgoralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2009-08-10Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralAmneal Pharmaceuticals2013-02-22Not AvailableUs
Klor-con Mtablet, extended release750 mgoralSandoz Inc.2014-09-01Not AvailableUs
Klor-con Mtablet, extended release1125 mgoralSandoz Inc.2014-09-01Not AvailableUs
Klor-con Mtablet, extended release1500 mgoralSandoz Inc.2014-09-01Not AvailableUs
Potassium Chloridetablet, extended release10 meqoralContract Pharmacy Services Pa2010-08-02Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralContract Pharmacy Services Pa2010-08-02Not AvailableUs
Potassium Chloridetablet, extended release20 meqoralContract Pharmacy Services Pa2010-08-02Not AvailableUs
Klor-con Mtablet, extended release1500 mgoralAphena Pharma Solutions Tennessee, Inc.2011-01-18Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralBlue Point Laboratories2013-12-022015-10-31Us
Potassium Chloridetablet, extended release20 meqoralBlue Point Laboratories2014-02-25Not AvailableUs
Potassium Chloridecapsule, extended release750 mgoralBlue Point Laboratories2013-06-23Not AvailableUs
Potassium Chloridetablet, extended release1500 mgoralAmerican Health Packaging2010-01-21Not AvailableUs
Potassium Chloridetablet, extended release10 meqoralAmerican Health Packaging2013-01-18Not AvailableUs
Potassium Chloridecapsule, extended release8 meqoralCarilion Materials Management2008-08-25Not AvailableUs
Klor-con Mtablet, extended release1500 mgoralMc Kesson Contract Packaging2011-12-05Not AvailableUs
Klor-con Mtablet, extended release750 mgoralMc Kesson Contract Packaging2011-12-07Not AvailableUs
Over the Counter ProductsNot Available
International Brands
NameCompany
K-DurNot Available
Kaon ClNot Available
KlotrixNot Available
Micro-KNot Available
Sando-KNot Available
Slow-KNot Available
Brand mixturesNot Available
SaltsNot Available
CategoriesNot Available
CAS number7447-40-7
WeightAverage: 74.551
Monoisotopic: 73.932559568
Chemical FormulaClK
InChI KeyWCUXLLCKKVVCTQ-UHFFFAOYSA-M
InChI
InChI=1S/ClH.K/h1H;/q;+1/p-1
IUPAC Name
potassium chloride
SMILES
[Cl-].[K+]
Taxonomy
DescriptionThis compound belongs to the class of inorganic compounds known as alkali metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is an alkali metal.
KingdomInorganic compounds
Super ClassMixed metal/non-metal compounds
ClassAlkali metal salts
Sub ClassAlkali metal chlorides
Direct ParentAlkali metal chlorides
Alternative Parents
Substituents
  • Alkali metal chloride
  • Inorganic chloride salt
  • Inorganic salt
  • Acyclic compound
Molecular FrameworkAcyclic compounds
External Descriptors
Pharmacology
IndicationFor use as an electrolyte replenisher and in the treatment of hypokalemia.
PharmacodynamicsThe potassium ion is in the principle intracellular cation of most body tissues. Potassium ions participate in a number of essential physiological processes including the maintenance of intracellular tonicity, the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, and the maintenance of normal renal function. The intracellular concentration of potassium is approximately 150 to 160 mEq per liter. The normal adult plasma concentration is 3.5 to 5 mEq per liter. An active ion transport system maintains this gradient across the plasma membrane. Potassium is a normal dietary constituent and under steady-state conditions the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. The usual dietary intake of potassium is 50 to 100 mEq per day. Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake. Such depletion usually develops as a consequence of therapy with diuretics, primarily or secondary hyperaldosteronism, diabetic ketoacidosis, or inadequate replacement of potassium in patients on prolonged parenteral nutrition. Depletion can develop rapidly with severe diarrhea, especially if associated with vomiting. Potassium depletion due to these causes is usually accompanied by concomitant loss of chloride and is manifested by hypokalemia and metabolic alkalosis. Potassium depletion may produce weakness, fatigue, disturbances of cardiac rhythm (primarily ectopic beats), prominent U-waves in the electrocardiogram, and, in advanced cases, flaccid paralysis and/or impaired ability to concentrate urine. If potassium depletion associated with metabolic alkalosis cannot be managed by correcting the fundamental cause of the deficiency, e.g., where the patient requires long-term diuretic therapy, supplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels. In rare circumstances (e.g., patients with renal tubular acidosis) potassium depletion may be associated with metabolic acidosis and hyperchloremia. In such patients, potassium replacement should be accomplished with potassium salts other than the chloride, such as potassium bicarbonate, potassium citrate, potassium acetate, or potassium gluconate.
Mechanism of actionSupplemental potassium in the form of high potassium food or potassium chloride may be able to restore normal potassium levels.
AbsorptionPotassium is a normal dietary constituent and under steady-state conditions the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine.
Volume of distributionNot Available
Protein bindingNot Available
Metabolism
Route of eliminationPotassium is a normal dietary constituent and, under steady-state conditions, the amount of potassium absorbed from the gastrointestinal tract is equal to the amount excreted in the urine. Potassium depletion will occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake.
Half lifeNot Available
ClearanceNot Available
ToxicityThe administration of oral potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired, of if potassium is administered too rapidly intravenously, potentially fatal hyperkalemia can result. It is important to recognize that hyperkalemia is usually asymptomatic and may be manifested only by an increased serum potassium concentration (6.5-8.0 mEq/L) and characteristic electrocardiographic changes (peaking of T-waves, loss of P-wave, depression of S-T segment, and prolongation of the QT interval). Late manifestations include muscle paralysis and cardiovascular collapse from cardiac arrest (9-12 mEq/L).
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9445
Blood Brain Barrier+0.975
Caco-2 permeable+0.6764
P-glycoprotein substrateNon-substrate0.9039
P-glycoprotein inhibitor INon-inhibitor0.9891
P-glycoprotein inhibitor IINon-inhibitor0.9866
Renal organic cation transporterNon-inhibitor0.9219
CYP450 2C9 substrateNon-substrate0.8116
CYP450 2D6 substrateNon-substrate0.717
CYP450 3A4 substrateNon-substrate0.7571
CYP450 1A2 substrateNon-inhibitor0.7551
CYP450 2C9 substrateNon-inhibitor0.8594
CYP450 2D6 substrateNon-inhibitor0.9314
CYP450 2C19 substrateNon-inhibitor0.8365
CYP450 3A4 substrateNon-inhibitor0.9576
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9002
Ames testNon AMES toxic0.6808
CarcinogenicityCarcinogens 0.7523
BiodegradationReady biodegradable0.6815
Rat acute toxicity1.9786 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9433
hERG inhibition (predictor II)Non-inhibitor0.9634
Pharmacoeconomics
Manufacturers
  • Novo nordisk inc
  • Savage laboratories inc div altana inc
  • Kv pharmaceutical co
  • Teva pharmaceuticals usa inc
  • Watson laboratories inc florida
  • Abraxis pharmaceutical products
  • Akorn inc
  • App pharmaceuticals llc
  • B braun medical inc
  • Baxter healthcare corp anesthesia and critical care
  • Baxter healthcare corp
  • Gd searle llc
  • Hospira inc
  • International medication system
  • Eli lilly and co
  • Luitpold pharmaceuticals inc
  • Miles laboratories inc
  • Pharma serve inc sub torigian laboratories
  • Watson laboratories inc
  • Future pak ltd
  • Upsher smith laboratories inc
  • Apothecon inc div bristol myers squibb
  • Abbott laboratories pharmaceutical products div
  • Copley pharmaceutical inc
  • Eurand america inc
  • Schering corp
  • Novartis pharmaceuticals corp
  • Upsher-Smith Laboratories Inc.
Packagers
Dosage forms
FormRouteStrength
Capsule, extended releaseoral10 meq
Capsule, extended releaseoral600 mg
Capsule, extended releaseoral750 mg
Capsule, extended releaseoral8 meq
Injectionintravenous149 mg/mL
Injectionintravenous2 meq/mL
Injection, solutionintravenous10 meq/100mL
Injection, solutionintravenous14.9 g/1000mL
Injection, solutionintravenous2 meq/mL
Injection, solutionintravenous200 meq/1000mL
Injection, solutionintravenous22.4 g/1000mL
Injection, solutionintravenous29.8 g/1000mL
Injection, solutionintravenous30 meq/100mL
Injection, solutionintravenous400 meq/1000mL
Injection, solutionintravenous7.46 g/1000mL
Injection, solution, concentrateintravenous149 mg/mL
Injection, solution, concentrateintravenous2 meq/mL
Injection, solution, concentrateparenteral14.9 g/100mL
Solutionoral20 meq/15mL
Solutionoral40 meq/15mL
Tabletoral20 meq
Tablet, extended releaseoral10 meq
Tablet, extended releaseoral1125 mg
Tablet, extended releaseoral1500 mg
Tablet, extended releaseoral20 meq
Tablet, extended releaseoral600 mg
Tablet, extended releaseoral750 mg
Tablet, film coated, extended releaseoral10 meq
Tablet, film coated, extended releaseoral1500 mg
Tablet, film coated, extended releaseoral20 meq
Tablet, film coated, extended releaseoral600 mg
Tablet, film coated, extended releaseoral750 mg
Tablet, film coated, extended releaseoral8 meq
Prices
Unit descriptionCostUnit
Klor-Con 100 20meq Packets Box106.77USD box
Kay Ciel 30 20meq Packets Box58.99USD box
Rum-K-SF 15% Liquid 473ml Bottle45.98USD bottle
Klor-Con 30 25meq Packets Box36.99USD box
Colyte 240 gm Solution26.0USD bottle
Colyte-Flavored 240 gm Solution18.17USD bottle
K-Lor 20meq Packets1.92USD packet
K-lyte tablet eff1.43USD tablet
K-lyte-cl 25 meq tablet eff1.43USD tablet
Micro-K 10meq capsule1.41USD capsule
Micro-K 8meq capsule1.21USD capsule
Potassium cl 25 meq tablet eff0.94USD tablet
Micro-k 10 meq extencaps0.91USD each
Potassium Chloride CR 10meq capsule0.9USD capsule
Potassium Chloride CR 8meq capsule0.87USD capsule
K-Tabs 10meq Controlled Release Tabs0.68USD tab
K-tab er 10 meq tablet0.66USD tablet
Kaochlor-eff 20 meq tablet0.59USD tablet
K-tab 10 meq tablet sa0.58USD tablet
K-Lyte 25 meq Effervescent Tablet0.58USD tablet
Klor-con m20 tablet0.57USD tablet
Klor-Con/EF 25meq Effervescent Tabs0.57USD tab
Klor-Con 8meq Controlled Release Tabs0.56USD tab
Klor-Con M20 20meq Controlled Release Tabs0.55USD tab
Potassium Chloride Crys CR 20meq Controlled Release Tabs0.53USD tab
Potassium cl 20 meq tablet er0.52USD tablet
Potassium cl 20 meq tablet sa0.52USD tablet
Klor-con 10 meq tablet0.5USD tablet
Klor-con m15 tablet0.5USD tablet
Klotrix 10meq Controlled Release Tabs0.5USD tab
Potassium cl er 20 meq tablet0.49USD tablet
Klor-con-ef 25 meq tablet eff0.4USD tablet
Micro-k 8 meq extencaps0.34USD each
Kaon-Cl-10 10meq Controlled Release Tabs0.3USD tab
Klor-con m10 tablet0.3USD tablet
Potassium cl er 10 meq tablet0.3USD tablet
Potassium cl 10 meq tablet sa0.29USD tablet
Potassium Chloride Crys CR 10meq Controlled Release Tabs0.28USD tab
Potassium Chloride CR 10meq Controlled Release Tabs0.27USD tab
Potassium cl er 8 meq tablet0.26USD tablet
Kaon-cl 10 meq tablet sa0.23USD tablet
Potassium cl 2 meq/ml vial0.23USD ml
K-Dur 20 meq Sustained-Release Tablet0.21USD tablet
Potassium Chloride CR 8meq Controlled Release Tabs0.18USD tab
Klor-con 8 meq tablet0.16USD tablet
Slow K 8 meq Sustained-Release Tablet0.16USD tablet
Micro-K Extencaps 8 meq Sustained-Release Capsule0.1USD capsule
Apo-K 8 meq Sustained-Release Tablet0.09USD tablet
Potassium Chloride 40 Meq/15ml(20%) Liquid0.06USD ml
Potassium Chloride 20 Meq/15ml(10%) Liquid0.03USD ml
Potassium chloride crystals0.02USD g
K-10 Oral Liquid 1.33 meq/ml Liquid0.02USD ml
Colyte with flavor packets0.01USD ml
Pms - Potassium Chloride 1.33 meq/ml Liquid0.01USD ml
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
PatentsNot Available
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point770 °CNot Available
water solubilityFreely solubleNot Available
Predicted Properties
PropertyValueSource
logP0.2ChemAxon
pKa (Strongest Acidic)-7ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
References
Synthesis Reference

Fritz Hagedorn, Gerd Peuschel, Arno Singewald, “Method for the production of potassium chloride with K.sub.2 O content of more than 55 weight percent.” U.S. Patent US5057208, issued July, 1955.

US5057208
General ReferenceNot Available
External Links
ATC CodesA12BA01B05XA01
AHFS Codes
  • 40:12.00
  • 40:34.00*
  • 88:29.00*
  • 92:02.00*
PDB EntriesNot Available
FDA labelDownload (632 KB)
MSDSDownload (72.6 KB)
Interactions
Drug Interactions
Drug
ClidiniumAnticholinergic agents such as clidinium may enhance the ulcerogenic effect of potassium chloride. Solid oral dosage forms of potassium chloride are contraindicated in patients with impaired gastric emptying (e.g., due to the effects of drugs such as many anticholinergics). Patients on drugs with substantial anticholinergic effects should avoid using any solid oral dosage form of potassium chloride; liquid or effervescent potassium preparations are possible alternatives.
TelmisartanPotassium Chloride may increase the hyperkalemic effect of Telmisartan. Monitor serum potassium levels during concomitant use.
TiotropiumThe ulcerative effects of solid oral dosage forms of KCl may be enhanced by Tiotropium, an anticholinergic. Anticholinergics slow gastric emptying, increasing the contact time between the gastrointestinal mucosa and KCl. Prolonged exposure to KCl increases the risk of gastric and intestinal irritation and ulceration. Solid oral dosage forms of KCl should be avoided; alternatives include liquid or effervescent potassium preparations.
TolterodineThe ulcerative effects of solid oral dosage forms of KCl may be enhanced by the anticholinergic, Tolterodine. Anticholinergics slow gastric emptying, increasing the contact time between the gastrointestinal mucosa and KCl. Prolonged exposure to KCl increases the risk of gastric and intestinal irritation and ulceration. Solid oral dosage forms of KCl should be avoided; alternatives include liquid or effervescent potassium preparations.
TrandolaprilThe potassium salt may increase the hyperkalemic effect of Trandolapril.
TrihexyphenidylThe ulcerative effects of solid oral dosage forms of KCl may be enhanced by Trihexyphenidyl, an anticholinergic. Anticholinergics slow gastric emptying, increasing the contact time between the gastrointestinal mucosa and KCl. Prolonged exposure to KCl increases the risk of gastric and intestinal irritation and ulceration. Solid oral dosage forms of KCl should be avoided; alternatives include liquid or effervescent potassium preparations.
TrimethobenzamideThe ulcerative effects of solid oral dosage forms of KCl may be enhanced by Trimethobenzamide, an anticholinergic. Anticholinergics slow gastric emptying, increasing the contact time between the gastrointestinal mucosa and KCl. Prolonged exposure to KCl increases the risk of gastric and intestinal irritation and ulceration. Solid oral dosage forms of KCl should be avoided; alternatives include liquid or effervescent potassium preparations.
TrospiumThe ulcerative effects of solid oral dosage forms of KCl may be enhanced by Trospium, an anticholinergic. Anticholinergics slow gastric emptying, increasing the contact time between the gastrointestinal mucosa and KCl. Prolonged exposure to KCl increases the risk of gastric and intestinal irritation and ulceration. Solid oral dosage forms of KCl should be avoided; alternatives include liquid or effervescent potassium preparations.
Food Interactions
  • Take with a full glass of water Take after a full meal.

Targets

1. Solute carrier family 12 member 2

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Solute carrier family 12 member 2 P55011 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Hebert SC: Bartter syndrome. Curr Opin Nephrol Hypertens. 2003 Sep;12(5):527-32. Pubmed

2. Solute carrier family 12 member 1

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: binder

Components

Name UniProt ID Details
Solute carrier family 12 member 1 Q13621 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Fujiwara TM, Bichet DG: Molecular biology of hereditary diabetes insipidus. J Am Soc Nephrol. 2005 Oct;16(10):2836-46. Epub 2005 Aug 10. Pubmed
  4. Bichet DG: Hereditary polyuric disorders: new concepts and differential diagnosis. Semin Nephrol. 2006 May;26(3):224-33. Pubmed
  5. Pressler CA, Heinzinger J, Jeck N, Waldegger P, Pechmann U, Reinalter S, Konrad M, Beetz R, Seyberth HW, Waldegger S: Late-onset manifestation of antenatal Bartter syndrome as a result of residual function of the mutated renal Na+-K+-2Cl- co-transporter. J Am Soc Nephrol. 2006 Aug;17(8):2136-42. Epub 2006 Jun 28. Pubmed
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. Pubmed

3. Solute carrier family 12 member 5

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Solute carrier family 12 member 5 Q9H2X9 Details

References:

  1. Takayama C, Inoue Y: Developmental localization of potassium chloride co-transporter 2 (KCC2) in the Purkinje cells of embryonic mouse cerebellum. Neurosci Res. 2007 Feb;57(2):322-5. Epub 2006 Nov 28. Pubmed
  2. Tornberg J, Segerstrale M, Kulesskaya N, Voikar V, Taira T, Airaksinen MS: KCC2-deficient mice show reduced sensitivity to diazepam, but normal alcohol-induced motor impairment, gaboxadol-induced sedation, and neurosteroid-induced hypnosis. Neuropsychopharmacology. 2007 Apr;32(4):911-8. Epub 2006 Aug 16. Pubmed
  3. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. Pubmed
  4. Takayama C, Inoue Y: Developmental localization of potassium chloride co-transporter 2 in granule cells of the early postnatal mouse cerebellum with special reference to the synapse formation. Neuroscience. 2006 Dec;143(3):757-67. Epub 2006 Sep 27. Pubmed
  5. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. Pubmed

4. Solute carrier family 12 member 6

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Solute carrier family 12 member 6 Q9UHW9 Details

References:

  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. Pubmed
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. Pubmed
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. Pubmed

5. Solute carrier family 12 member 7

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Solute carrier family 12 member 7 Q9Y666 Details

References:

  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. Pubmed
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. Pubmed
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. Pubmed

6. Solute carrier family 12 member 4

Kind: protein

Organism: Human

Pharmacological action: unknown

Components

Name UniProt ID Details
Solute carrier family 12 member 4 Q9UP95 Details

References:

  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. Pubmed
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. Pubmed
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. Pubmed

Transporters

1. Solute carrier family 12 member 2

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Solute carrier family 12 member 2 P55011 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Hebert SC: Bartter syndrome. Curr Opin Nephrol Hypertens. 2003 Sep;12(5):527-32. Pubmed

2. Solute carrier family 12 member 1

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Solute carrier family 12 member 1 Q13621 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Fujiwara TM, Bichet DG: Molecular biology of hereditary diabetes insipidus. J Am Soc Nephrol. 2005 Oct;16(10):2836-46. Epub 2005 Aug 10. Pubmed
  4. Bichet DG: Hereditary polyuric disorders: new concepts and differential diagnosis. Semin Nephrol. 2006 May;26(3):224-33. Pubmed
  5. Pressler CA, Heinzinger J, Jeck N, Waldegger P, Pechmann U, Reinalter S, Konrad M, Beetz R, Seyberth HW, Waldegger S: Late-onset manifestation of antenatal Bartter syndrome as a result of residual function of the mutated renal Na+-K+-2Cl- co-transporter. J Am Soc Nephrol. 2006 Aug;17(8):2136-42. Epub 2006 Jun 28. Pubmed
  6. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. Pubmed

3. Solute carrier family 12 member 5

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Solute carrier family 12 member 5 Q9H2X9 Details

References:

  1. Takayama C, Inoue Y: Developmental localization of potassium chloride co-transporter 2 (KCC2) in the Purkinje cells of embryonic mouse cerebellum. Neurosci Res. 2007 Feb;57(2):322-5. Epub 2006 Nov 28. Pubmed
  2. Tornberg J, Segerstrale M, Kulesskaya N, Voikar V, Taira T, Airaksinen MS: KCC2-deficient mice show reduced sensitivity to diazepam, but normal alcohol-induced motor impairment, gaboxadol-induced sedation, and neurosteroid-induced hypnosis. Neuropsychopharmacology. 2007 Apr;32(4):911-8. Epub 2006 Aug 16. Pubmed
  3. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. Pubmed
  4. Takayama C, Inoue Y: Developmental localization of potassium chloride co-transporter 2 in granule cells of the early postnatal mouse cerebellum with special reference to the synapse formation. Neuroscience. 2006 Dec;143(3):757-67. Epub 2006 Sep 27. Pubmed
  5. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. Pubmed

4. Solute carrier family 12 member 6

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Solute carrier family 12 member 6 Q9UHW9 Details

References:

  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. Pubmed
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. Pubmed
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. Pubmed

5. Solute carrier family 12 member 7

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Solute carrier family 12 member 7 Q9Y666 Details

References:

  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. Pubmed
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. Pubmed
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. Pubmed

6. Solute carrier family 12 member 4

Kind: protein

Organism: Human

Pharmacological action: unknown

Actions: substrate

Components

Name UniProt ID Details
Solute carrier family 12 member 4 Q9UP95 Details

References:

  1. Misri S, Chimote AA, Adragna NC, Warwar R, Brown TL, Lauf PK: KCC isoforms in a human lens epithelial cell line (B3) and lens tissue extracts. Exp Eye Res. 2006 Nov;83(5):1287-94. Epub 2006 Sep 1. Pubmed
  2. Capo-Aponte JE, Wang Z, Bildin VN, Iserovich P, Pan Z, Zhang F, Pokorny KS, Reinach PS: Functional and molecular characterization of multiple K-Cl cotransporter isoforms in corneal epithelial cells. Exp Eye Res. 2007 Jun;84(6):1090-103. Epub 2007 Feb 16. Pubmed
  3. Klein T, Cooper TG, Yeung CH: The role of potassium chloride cotransporters in murine and human sperm volume regulation. Biol Reprod. 2006 Dec;75(6):853-8. Epub 2006 Aug 30. Pubmed

Comments
comments powered by Disqus
Drug created on June 13, 2005 07:24 / Updated on September 16, 2013 17:12