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Identification
NameCalcium Chloride
Accession NumberDB01164  (APRD00840)
TypeSmall Molecule
GroupsApproved
DescriptionCalcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement. It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers. [Wikipedia]
Structure
Thumb
Synonyms
Calcium chloride anhydrous
Calcium chloride, anhydrous
calcium(2+) chloride
External Identifiers
  • E-509
  • INS NO.509
  • INS-509
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
10% Calcium Chloride Injection USPsolution100 mgintravenousHospira Healthcare Corporation1981-12-31Not applicableCanada
Calciject Inj 100mg/mlliquid100 mgintravenousOmega Laboratories Ltd1990-12-31Not applicableCanada
Calcium Chlorideinjection, solution100 mg/mLintravenousHospira, Inc.2011-03-09Not applicableUs
Calcium Chlorideinjection, solution100 mg/mLintravenousGeneral Injectables & Vaccines, Inc2010-07-01Not applicableUs
Calcium Chlorideinjection, solution100 mg/mLintravenousCardinal Health2011-03-09Not applicableUs
Calcium Chloride Additive 0.13-4.5lpowder3.78 gdialysisHaemotec Inc.2006-12-012011-07-27Canada
Calcium Chloride Bp - Additive for Concentrated Haemodialysis Solutionspowder12.32 gdialysisGenpharm Ulc1998-06-182004-07-30Canada
Calcium Chloride Bp - Additive for Concentrated Haemodialysis Solutionspowder3.78 gdialysisGenpharm Ulc1998-06-182004-07-30Canada
Calcium Chloride for Haemodialysispowder7.45 gdialysisChief Medical Supplies Ltd2013-03-26Not applicableCanada
Calcium Chloride Inj 10%liquid100 mgintravenousInternational Medication Systems Ltd.1971-12-311997-08-15Canada
Calcium Chloride Injection 100mg/mlliquid100 mgintravenousAstrazeneca Canada Inc1986-12-312004-11-15Canada
Calcium-35 0.25 - 10powder for solution12.9 gdialysisAlthin Biopharm Inc.1988-12-312001-08-27Canada
Calcium-35 0.25 - 4.5powder for solution5.8 gdialysisBaxter Corporation1988-12-312002-08-01Canada
Calcium-36.8 0.25-4.5powder6.1 gdialysisBaxter Corporation1995-12-312004-08-05Canada
Calcium-36.8 0.5-4.5powder12.2 gdialysisAlthin Biopharm Inc.1995-12-311999-09-23Canada
Calcium-45 0.25-4.5powder7.45 gdialysisBaxter Corporation1995-12-31Not applicableCanada
Calcium-45 0.5-4.5powder14.9 gdialysisBaxter Corporation1995-12-31Not applicableCanada
Approved Generic Prescription ProductsNot Available
Approved Over the Counter ProductsNot Available
Unapproved/Other Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Calcium Chlorideinjection100 mg/mLintravenousCardinal Health2011-06-14Not applicableUs
Calcium Chlorideinjection, solution100 mg/mLintravenous; intraventricularHospira, Inc.1984-09-17Not applicableUs
Calcium Chlorideinjection, solution100 mg/mLintravenousGeneral Injectables & Vaccines, Inc2010-03-01Not applicableUs
Calcium Chlorideinjection100 mg/mLintravenous; intraventricularInternational Medication Systems, Limited1973-05-01Not applicableUs
Calcium Chlorideinjection, solution100 mg/mLintravenousAmerican Regent, Inc.1990-09-30Not applicableUs
Calcium Chlorideinjection, solution100 mg/mLintravenousGeneral Injectables & Vaccines, Inc.2010-03-01Not applicableUs
Calcium Chlorideinjection100 mg/mLparenteralAmphastar Pharmaceuticals, Inc.2000-06-01Not applicableUs
Calcium Chlorideinjection, solution100 mg/mLintravenous; intraventricularCardinal Health1984-09-17Not applicableUs
Calcium Chlorideinjection, solution20 mg/mLintravenousCantrell Drug Company2011-03-08Not applicableUs
International Brands
NameCompany
JarcalNot Available
LiquiCal-D 400Not Available
Brand mixtures
NameLabellerIngredients
(40 Mmols/l) Potassium Chloride In Lactated Ringer's Injection USPBaxter Corporation
5% Dextrose In Lactated Ringer's InjectionB. Braun Medical Inc
Accusol 35 K0Chief Medical Supplies Ltd
Acetate Concentrate R07376Bdh Inc.
Acid Concentrate D12028Althin Biopharm Inc.
Acid Concentrate D12054Althin Biopharm Inc.
Acid Concentrate D12092Althin Biopharm Inc.
Acid Concentrate D12093Baxter Corporation
Acid Concentrate D12095Baxter Corporation
Acid Concentrate D12119Althin Biopharm Inc.
Acid Concentrate D12132Althin Biopharm Inc.
Acid Concentrate D12150Althin Biopharm Inc.
Acid Concentrate D12247Althin Biopharm Inc.
Acid Concentrate D12250Althin Biopharm Inc.
Acid Concentrate D12261Althin Biopharm Inc.
Acid Concentrate D12268Althin Biopharm Inc.
Acid Concentrate (r04146)Genpharm Ulc
Acid Concentrate (r04938)Genpharm Ulc
Acid Concentrate (r04968)Genpharm Ulc
Acid Concentrate (r04969)Genpharm Ulc
Acid Concentrate (r04974)Genpharm Ulc
Acid Concentrate (r04975)Genpharm Ulc
Acid Concentrate (r04976)Genpharm Ulc
Acid Concentrate (r04981)Genpharm Ulc
Acid Concentrate (r04984)Genpharm Ulc
Acid Concentrate (ro4147)Genpharm Ulc
Acid Concentrate (ro4148)Genpharm Ulc
Acid Concentrate (ro9503)Genpharm Ulc
Acid Concentrate (rz262c)Genpharm Ulc
Acid Concentrate (rz271c)Genpharm Ulc
Acid Concentrate (rz272c)Genpharm Ulc
Acid Concentrate (rz274c)Genpharm Ulc
Acid Concentrate (rz275c)Genpharm Ulc
Acid Concentrate 2100Baxter Corporation
Acid Concentrate 2101Baxter Corporation
Acid Concentrate 2102Baxter Corporation
Acid Concentrate 2105Baxter Corporation
Acid Concentrate 2106Baxter Corporation
Acid Concentrate 2109Althin Biopharm Inc.
Acid Concentrate 2112Western Dialysis Supplies Ltd.
Acid Concentrate 2113Baxter Corporation
Acid Concentrate 2116Baxter Corporation
Acid Concentrate 2117Baxter Corporation
Acid Concentrate 2119Baxter Corporation
Acid Concentrate 2120Baxter Corporation
Acid Concentrate 2121Baxter Corporation
Acid Concentrate 2122Baxter Corporation
Acid Concentrate 2123Baxter Corporation
Acid Concentrate 2125Baxter Corporation
Acid Concentrate 2126Baxter Corporation
Acid Concentrate 2128Baxter Corporation
Acid Concentrate 2129Baxter Corporation
Acid Concentrate 2131Baxter Corporation
Acid Concentrate 2132Baxter Corporation
Acid Concentrate 2135Baxter Corporation
Acid Concentrate 2139Baxter Corporation
Acid Concentrate 2147Baxter Corporation
Acid Concentrate 2148Baxter Corporation
Acid Concentrate 2151Baxter Corporation
Acid Concentrate 2152Baxter Corporation
Acid Concentrate 2155Baxter Corporation
Acid Concentrate 2156Baxter Corporation
Acid Concentrate 2161Baxter Corporation
Acid Concentrate 2162Baxter Corporation
Acid Concentrate 2163Baxter Corporation
Acid Concentrate 2165Althin Biopharm Inc.
Acid Concentrate 2166Althin Biopharm Inc.
Acid Concentrate 2168Althin Biopharm Inc.
Acid Concentrate 2171Baxter Corporation
Acid Concentrate 2175Baxter Corporation
Acid Concentrate 2182Baxter Corporation
Acid Concentrate 2185Baxter Corporation
Acid Concentrate 2186Baxter Corporation
Acid Concentrate 2189Baxter Corporation
Acid Concentrate 2190Baxter Corporation
Acid Concentrate 2196Althin Biopharm Inc.
Acid Concentrate 2198Baxter Corporation
Acid Concentrate 3186Baxter Corporation
Acid Concentrate 3187Baxter Corporation
Acid Concentrate A1220Chief Medical Supplies Ltd
Acid Concentrate A1221Chief Medical Supplies Ltd
Acid Concentrate A1222Chief Medical Supplies Ltd
Acid Concentrate A1223Chief Medical Supplies Ltd
Acid Concentrate A1224Chief Medical Supplies Ltd
Acid Concentrate A1225Chief Medical Supplies Ltd
Acid Concentrate A1226Chief Medical Supplies Ltd
Acid Concentrate A1227Chief Medical Supplies Ltd
Acid Concentrate A1228Chief Medical Supplies Ltd
Acid Concentrate A1229Chief Medical Supplies Ltd
Acid Concentrate A1230Chief Medical Supplies Ltd
Acid Concentrate A1231Chief Medical Supplies Ltd
Acid Concentrate A1241Chief Medical Supplies Ltd
Acid Concentrate A1242Chief Medical Supplies Ltd
Acid Concentrate A1243Chief Medical Supplies Ltd
Acid Concentrate A1245Chief Medical Supplies Ltd
Acid Concentrate A1246Chief Medical Supplies Ltd
Acid Concentrate A1251Chief Medical Supplies Ltd
Acid Concentrate A1252Chief Medical Supplies Ltd
Acid Concentrate A1253Chief Medical Supplies Ltd
Acid Concentrate A1255Chief Medical Supplies Ltd
Acid Concentrate A1261Chief Medical Supplies Ltd
Acid Concentrate A1262Chief Medical Supplies Ltd
Acid Concentrate A1263Chief Medical Supplies Ltd
Acid Concentrate A1264Chief Medical Supplies Ltd
Acid Concentrate A1265Chief Medical Supplies Ltd
Acid Concentrate A1266Chief Medical Supplies Ltd
Acid Concentrate A1267Chief Medical Supplies Ltd
Acid Concentrate A1268Chief Medical Supplies Ltd
Acid Concentrate A1269Chief Medical Supplies Ltd
Acid Concentrate A1270Chief Medical Supplies Ltd
Acid Concentrate A1271Chief Medical Supplies Ltd
Acid Concentrate A1272Chief Medical Supplies Ltd
Acid Concentrate A1273Chief Medical Supplies Ltd
Acid Concentrate A1274Chief Medical Supplies Ltd
Acid Concentrate A1275Chief Medical Supplies Ltd
Acid Concentrate A1276Chief Medical Supplies Ltd
Acid Concentrate A1277Chief Medical Supplies Ltd
Acid Concentrate A1278Chief Medical Supplies Ltd
Acid Concentrate A1279Chief Medical Supplies Ltd
Acid Concentrate A1280Chief Medical Supplies Ltd
Acid Concentrate A1294Chief Medical Supplies Ltd
Acid Concentrate A1295Chief Medical Supplies Ltd
Acid Concentrate A1296Chief Medical Supplies Ltd
Acid Concentrate A1297Chief Medical Supplies Ltd
Acid Concentrate A1298Chief Medical Supplies Ltd
Acid Concentrate Bp Ro4151Genpharm Ulc
Acid Concentrate Bp Ro9505Genpharm Ulc
Acid Concentrate Bp Ro9506Genpharm Ulc
Acid Concentrate Bp Ro9507Genpharm Ulc
Acid Concentrate Bp Rz267cGenpharm Ulc
Acid Concentrate Bp Rz278cGenpharm Ulc
Acid Concentrate Bp Rz279cGenpharm Ulc
Acid Concentrate D 12219 LiqBio Pharm Inc.
Acid Concentrate D-12287Baxter Corporation
Acid Concentrate D-18003Baxter Corporation
Acid Concentrate D-18006Baxter Corporation
Acid Concentrate D12067Althin Biopharm Inc.
Acid Concentrate D12091Althin Biopharm Inc.
Acid Concentrate D12094Baxter Corporation
Acid Concentrate D12112Baxter Corporation
Acid Concentrate D12117Baxter Corporation
Acid Concentrate D12135Baxter Corporation
Acid Concentrate D12143Baxter Corporation
Acid Concentrate D12146Baxter Corporation
Acid Concentrate D12167Baxter Corporation
Acid Concentrate D12184Althin Biopharm Inc.
Acid Concentrate D12185Baxter Corporation
Acid Concentrate D12186Baxter Corporation
Acid Concentrate D12187Althin Biopharm Inc.
Acid Concentrate D12188Baxter Corporation
Acid Concentrate D12196Althin Biopharm Inc.
Acid Concentrate D12197Althin Biopharm Inc.
Acid Concentrate D12201Baxter Corporation
Acid Concentrate D12204Baxter Corporation
Acid Concentrate D12205Althin Biopharm Inc.
Acid Concentrate D12207Baxter Corporation
Acid Concentrate D12209Baxter Corporation
Acid Concentrate D12220Althin Biopharm Inc.
Acid Concentrate D12221Baxter Corporation
Acid Concentrate D12225Althin Biopharm Inc.
Acid Concentrate D12236Baxter Corporation
Acid Concentrate D12248Baxter Corporation
Acid Concentrate D12249Althin Biopharm Inc.
Acid Concentrate D12251Althin Biopharm Inc.
Acid Concentrate D12252Althin Biopharm Inc.
Acid Concentrate D12255Baxter Corporation
Acid Concentrate D12259Baxter Corporation
Acid Concentrate D12260Althin Biopharm Inc.
Acid Concentrate D12262Baxter Corporation
Acid Concentrate D12264Baxter Corporation
Acid Concentrate D12265Baxter Corporation
Acid Concentrate D12266Althin Biopharm Inc.
Acid Concentrate D12267Baxter Corporation
Acid Concentrate D12269Althin Biopharm Inc.
Acid Concentrate D12270Baxter Corporation
Acid Concentrate D12271Baxter Corporation
Acid Concentrate D12272Baxter Corporation
Acid Concentrate D12273Baxter Corporation
Acid Concentrate D12274Baxter Corporation
Acid Concentrate D12275Baxter Corporation
Acid Concentrate D12282Baxter Corporation
Acid Concentrate D12284Baxter Corporation
Acid Concentrate D12285Baxter Corporation
Acid Concentrate D12286Baxter Corporation
Acid Concentrate D12290Baxter Corporation
Acid Concentrate D12291Baxter Corporation
Acid Concentrate D12292Baxter Corporation
Acid Concentrate D12293Baxter Corporation
Acid Concentrate D12294Baxter Corporation
Acid Concentrate D12299Baxter Corporation
Acid Concentrate D12300Baxter Corporation
Acid Concentrate D12301Baxter Corporation
Acid Concentrate D12302Baxter Corporation
Acid Concentrate D12303Althin Biopharm Inc.
Acid Concentrate D12304Baxter Corporation
Acid Concentrate D12305Baxter Corporation
Acid Concentrate D12306Baxter Corporation
Acid Concentrate D12308Baxter Corporation
Acid Concentrate D12309Baxter Corporation
Acid Concentrate D12310Baxter Corporation
Acid Concentrate D12311Baxter Corporation
Acid Concentrate D12315Althin Biopharm Inc.
Acid Concentrate D12316Baxter Corporation
Acid Concentrate D12318Althin Biopharm Inc.
Acid Concentrate D12319Althin Biopharm Inc.
Acid Concentrate D13001Althin Biopharm Inc.
Acid Concentrate D18000Althin Biopharm Inc.
Acid Concentrate D18001Althin Biopharm Inc.
Acid Concentrate D18008Althin Biopharm Inc.
Acid Concentrate D18009Althin Biopharm Inc.
Acid Concentrate Ro4131Genpharm Ulc
Acid Concentrate Ro4132Genpharm Ulc
Acid Concentrate Ro4136Genpharm Ulc
Acid Concentrate Ro4137Genpharm Ulc
Acid Concentrate Ro4138Genpharm Ulc
Acid Concentrate Ro4144Genpharm Ulc
Acid Concentrate Ro4145Genpharm Ulc
Acid Concentrate Ro4947Genpharm Ulc
Acid Concentrate Ro4979Genpharm Ulc
Acid Concentrate Ro4983Genpharm Ulc
Acid Concentrate Ro9500Genpharm Ulc
Acid Concentrate Ro9501Genpharm Ulc
Acid Concentrate Ro9502Genpharm Ulc
Acid Concentrate Rx252cBdh Inc.
Acid Concentrate Rx253cBdh Inc.
Acid Concentrate Rz110cGenpharm Ulc
Acid Concentrate Rz111cGenpharm Ulc
Acid Concentrate Rz119cGenpharm Ulc
Acid Concentrate Rz123cGenpharm Ulc
Acid Concentrate Rz127cGenpharm Ulc
Acid Concentrate Rz144cGenpharm Ulc
Acid Concentrate Rz150cGenpharm Ulc
Acid Concentrate Rz153cGenpharm Ulc
Acid Concentrate Rz164cGenpharm Ulc
Acid Concentrate Rz167cGenpharm Ulc
Acid Concentrate Rz171cGenpharm Ulc
Acid Concentrate Rz183cGenpharm Ulc
Acid Concentrate Rz185cGenpharm Ulc
Acid Concentrate Rz186cGenpharm Ulc
Acid Concentrate Rz194cGenpharm Ulc
Acid Concentrate Rz195cGenpharm Ulc
Acid Concentrate Rz196cGenpharm Ulc
Acid Concentrate Rz202cGenpharm Ulc
Acid Concentrate Rz203cGenpharm Ulc
Acid Concentrate Rz205cGenpharm Ulc
Acid Concentrate Rz206cGenpharm Ulc
Acid Concentrate Rz207cGenpharm Ulc
Acid Concentrate Rz208cGenpharm Ulc
Acid Concentrate Rz210cGenpharm Ulc
Acid Concentrate Rz211cGenpharm Ulc
Acid Concentrate Rz212cGenpharm Ulc
Acid Concentrate Rz213cGenpharm Ulc
Acid Concentrate Rz247cGenpharm Ulc
Acid Concentrate Rz248cGenpharm Ulc
Acid Concentrate Rz249cGenpharm Ulc
Acid Concentrate Rz254cGenpharm Ulc
Acid Concentrate Rz264cGenpharm Ulc
Acid Concentrate Rz265cGenpharm Ulc
Acid Concentrate-r04948 LiqBdh Inc.
Acid Concentrate(36.83x) R04900Bdh Inc.
Acid Concentrate(36.83x) R04906Bdh Inc.
Acid Conentrate (r04930)Genpharm Ulc
Acid Hemodialysis Conc Sb 1003Renal Systems, Division Of Minntech Corp.
Amo Endosol ExtraAmo Canada Company
Amo Endosol SolutionAmo Canada Company
Balance 1.5% Glucose, 1.25mmol/l CalciumFresenius Medical Care Deutchland Gmbh
Balance 1.5% Glucose, 1.75mmol/l CalciumFresenius Medical Care Deutchland Gmbh
Balance 2.3% Glucose, 1.25mmol/l CalciumFresenius Medical Care Deutchland Gmbh
Balance 2.3% Glucose, 1.75mmol/l CalciumFresenius Medical Care Deutchland Gmbh
Balance 4.25% Glucose, 1.25mmol/l CalciumFresenius Medical Care Deutchland Gmbh
Balance 4.25% Glucose, 1.75mmol/l CalciumFresenius Medical Care Deutchland Gmbh
Balanced SaltB. Braun Medical Inc.
Balanced Salt SolutionHospira Healthcare Corporation
Bicarb Hemodial Conc 36.83Bicarbolyte Corporation
Bicarb Hemodial Conc 36.83x AcidBicarbolyte Corporation
Bicarbolyte Bicar Hemodialsis ConcBicarbolyte Corporation
Bicarbolyte Bicar Hemodialysis ConcBicarbolyte Corporation
Bicavera 1.5% GlucoseFresenius Medical Care Canada Inc
Bicavera 2.3% GlucoseFresenius Medical Care Canada Inc
Bicavera 4.25% GlucoseFresenius Medical Care Canada Inc
Bicavera Forte 1.5% GlucoseFresenius Medical Care Canada Inc
Bicavera Forte 2.3% GlucoseFresenius Medical Care Canada Inc
Bicavera Forte 4.25% GlucoseFresenius Medical Care Canada Inc
BssAlcon Laboratories, Inc.
Bss PlusAlcon Canada Inc
Caneal Peritoneal Dialysis SolutionChief Medical Supplies Ltd
CardioplegicBaxter Healthcare Corporation
Citrasate C0125Chief Medical Supplies Ltd
Citrasate C10125Chief Medical Supplies Ltd
Citrasate C1125Chief Medical Supplies Ltd
Citrasate C1150Chief Medical Supplies Ltd
Citrasate C2125Chief Medical Supplies Ltd
Citrasate C2150Chief Medical Supplies Ltd
Citrasate C3125Chief Medical Supplies Ltd
Citrasate C3150Chief Medical Supplies Ltd
Citrasate C4125Chief Medical Supplies Ltd
Clinimix EBaxter Healthcare Corporation
Concentrated Haemodialysis Solution Bp-rz266cGenpharm Ulc
Concentrated Haemodialysis Solution Bp-rz270cGenpharm Ulc
D-12043 Sol Conc Electrolyt Pour DialyBio Pharm Inc.
D12006Bio Pharm Inc.
D12034 Conc Electrolyte Renal DialysisBio Pharm Inc.
D12046 Conc Electrolyte Renal DialysisBio Pharm Inc.
D12230 LiqBio Pharm Inc.
DelflexFresenius Medical Care North America
Delflex A Perit.dial.soln W.4.25%dext.low mgFresenius Usa Manufacturing Inc
Delflex A Perit.dial.solN.W.1.5%dext.low mgFresenius Usa Manufacturing Inc
Delflex A Perit.dial.solN.W.2.5%dext.low mgFresenius Usa Manufacturing Inc
Delflex A Periton.dial.soln. W.2.5% DextroseFresenius Usa Manufacturing Inc
Delflex A Periton.dial.solN.W.1.5% DextroseFresenius Usa Manufacturing Inc
Delflex A Periton.dial.solN.W.4.25% DextroseFresenius Usa Manufacturing Inc
Delflex Neutral PhFresenius Medical Care North America
Delflex Perit.dial.soL.1.5%dex.low Ca Low mgFresenius Usa Manufacturing Inc
Delflex Perit.dial.soL.2.5%dex.low Ca Low mgFresenius Usa Manufacturing Inc
Delflex Perit.dial.soL.4.25%dex.low Calow mgFresenius Usa Manufacturing Inc
Delflex Peritoneal Dialysis Solution With 0.5% DextroseFresenius Medical Care Canada Inc
Dextrose 2.5% In Half Strength Lactated Ringer's Injection, USPB. Braun Medical Inc
Dextrose 5% In Lactated RingersHospira Healthcare Corporation
Dextrose In Lactated RingersB. Braun Medical Inc.
Dianeal Low Calcium With DextroseBaxter Healthcare Corporation
Dianeal Pd 101 Capd Solution W 0.5% DextroseBaxter Corporation
Dianeal Pd 101 Capd Solution W 1.5% DextroseBaxter Corporation
Dianeal Pd 101 Capd Solution W 2.5% DextroseBaxter Corporation
Dianeal Pd 101 Capd Solution W 4.25% DextroseBaxter Corporation
Dianeal Pd 102 Capd Solution W 1.5% DextroseBaxter Corporation
Dianeal Pd 102 Capd Solution W 4.25% DextroseBaxter Corporation
Dianeal Pd 104 Capd Solution W 0.5% DextroseBaxter Corporation
Dianeal Pd-2 With DextroseBaxter Healthcare Corporation
Dianeal Pd109 Capd SolutionBaxter Corporation
Dianeal Pd4 Capd Solution With 1.5% Dextrose and 2.5meq/l CalciumBaxter Corporation
Dianeal Pd4 Capd Solution With 2.5% Dextrose and 2.5meq/l CalciumBaxter Corporation
Dianeal Pd4 Capd Solution With 4.25% Dextrose and 2.5meq/l CalciumBaxter Corporation
Dioptic's Balanced Salt SolutionDioptic Pharmaceuticals Inc
Elliott's Solution AHospira Healthcare Corporation
ExtranealBaxter Healthcare Corporation
EyestreamAlcon Canada Inc
H-629Haemotec Inc.
H-700Haemotec Inc.
H-701Haemotec Inc.
H-702Haemotec Inc.
H-706Haemotec Inc.
H-710Haemotec Inc.
H.E.L.P.bicelB. Braun Avitum Ag
Haemosol H-200Haemotec Inc.
Haemosol H-201Haemotec Inc.
Haemosol H-202Haemotec Inc.
Haemosol H-206Haemotec Inc.
Haemosol H-208Haemotec Inc.
Haemosol H-223Haemotec Inc.
Haemosol H-224Haemotec Inc.
Haemosol H-225Haemotec Inc.
Haemosol H-226Haemotec Inc.
Haemosol H-227Haemotec Inc.
Haemosol H-228Haemotec Inc.
Haemosol H-229Haemotec Inc.
Haemosol H-230Haemotec Inc.
Haemosol H-232Haemotec Inc.
Haemosol H-250Haemotec Inc.
Haemosol H-251Haemotec Inc.
Haemosol H-252Haemotec Inc.
Haemosol H-253Haemotec Inc.
Haemosol H-254Haemotec Inc.
Haemosol H-260Haemotec Inc.
Haemosol H-320Haemotec Inc.
Haemosol H-321Haemotec Inc.
Haemosol H-330Haemotec Inc.
Haemosol H-331Haemotec Inc.
Haemosol H-332Haemotec Inc.
Haemosol H-400Haemotec Inc.
Haemosol H-401Haemotec Inc.
Haemosol H-402Haemotec Inc.
Haemosol H-404Haemotec Inc.
Haemosol H-407Haemotec Inc.
Haemosol H-408Haemotec Inc.
Haemosol H-410Haemotec Inc.
Haemosol H-601Haemotec Inc.
Haemosol H-602Haemotec Inc.
Haemosol H-608Haemotec Inc.
Haemosol H-615Haemotec Inc.
Haemosol H-616Haemotec Inc.
Haemosol H-617Haemotec Inc.
Haemosol H-623Haemotec Inc.
Haemosol H-624Haemotec Inc.
Haemosol H-625Haemotec Inc.
Haemosol H-630Haemotec Inc.
Haemosol H-631Haemotec Inc.
Haemosol H-661Haemotec Inc.
Haemosol H-690Haemotec Inc.
Hemasate Ultra Hs0125Chief Medical Supplies Ltd
Hemasate Ultra Hs1125Chief Medical Supplies Ltd
Hemasate Ultra Hs1150Chief Medical Supplies Ltd
Hemasate Ultra Hs2125Chief Medical Supplies Ltd
Hemasate Ultra Hs2150Chief Medical Supplies Ltd
Hemasate Ultra Hs3125Chief Medical Supplies Ltd
Hemasate Ultra Hs3150Chief Medical Supplies Ltd
Hemasate Ultra Hs4125Chief Medical Supplies Ltd
Hemosate Ultra Hs0125Tqm Enterprises Limited
Hemosate Ultra Hs1125Tqm Enterprises Limited
Hemosate Ultra Hs1150Tqm Enterprises Limited
Hemosate Ultra Hs2125Tqm Enterprises Limited
Hemosate Ultra Hs2150Tqm Enterprises Limited
Hemosate Ultra Hs3125Tqm Enterprises Limited
Hemosate Ultra Hs3150Tqm Enterprises Limited
Hemosate Ultra Hs4125Tqm Enterprises Limited
Hemosol Lg2Gambro Inc
Hemosol Lg4Gambro Inc
Hemosol LoGambro Inc
Hyperlyte CRB. Braun Medical Inc.
Hyperlyte CR Multi-electrolyte ConcentrateB. Braun Medical Inc
Inpersol Lc With Dextrose 1.5% LiqAbbott Laboratories, Limited
Inpersol Lc With Dextrose 2.5% LiqAbbott Laboratories, Limited
Inpersol Lc With Dextrose 4.25% LiqAbbott Laboratories, Limited
Inpersol Lm W 1.5% DextroseAbbott Laboratories, Limited
Inpersol Lm W 2.5% DextroseAbbott Laboratories, Limited
Inpersol Lm W 4.25% DextroseAbbott Laboratories, Limited
Inpersol W Dextrose 1.5%Abbott Laboratories, Limited
Inpersol W Dextrose 2.5%Abbott Laboratories, Limited
Inpersol W Dextrose 4.25% InjAbbott Laboratories, Limited
Inpersol With Dextrose 0.5%Abbott Laboratories, Limited
Iocare Balanced Salt SolutionIolab Pharmaceuticals
Isolyte R In 5% DextroseB. Braun Medical Inc
K+36.8Baxter Corporation
K1 Liq R04911Bdh Inc.
K1 Liq R04978Bdh Inc.
K2 Liq R04902Bdh Inc.
K2 With Glucose Liq R04977Bdh Inc.
Lactated Ringer's InjectionHospira Healthcare Corporation
Lactated Ringer's Injection USPB. Braun Medical Inc
Lactated Ringer's IrrigationHospira Healthcare Corporation
Lactated Ringer's Irrigation SolBaxter Corporation
Lactated RingersB. Braun Medical Inc.
Lactated Ringers and DextroseBaxter Healthcare Corporation
Lactated Ringers Inj USPBaxter Corporation
Lactated Ringers Inj W 5% DextroseBaxter Corporation
Lactated Ringers IrrigationB. Braun Medical Inc.
Moi-stir Oral SwabsticksSolvay Pharma Inc
Moi-stir SpraySolvay Pharma Inc
Multiple Electrolyte Additive Liq Formula 1Baxter Corporation
Naturalyte H-200Fresenius Medical Care Canada Inc
Naturalyte H-201Fresenius Medical Care Canada Inc
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Salts
Name/CASStructureProperties
Calcium chloride dihydrate
10035-04-8
Thumb
  • InChI Key: LLSDKQJKOVVTOJ-UHFFFAOYSA-L
  • Monoisotopic Mass: 145.921425941
  • Average Mass: 147.015
DBSALT000772
Categories
UNIIOFM21057LP
CAS number10043-52-4
WeightAverage: 110.984
Monoisotopic: 109.900296569
Chemical FormulaCaCl2
InChI KeyInChIKey=UXVMQQNJUSDDNG-UHFFFAOYSA-L
InChI
InChI=1S/Ca.2ClH/h;2*1H/q+2;;/p-2
IUPAC Name
calcium dichloride
SMILES
[Cl-].[Cl-].[Ca++]
Taxonomy
DescriptionThis compound belongs to the class of inorganic compounds known as alkaline earth metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a lanthanide.
KingdomInorganic compounds
Super ClassMixed metal/non-metal compounds
ClassAlkaline earth metal salts
Sub ClassAlkaline earth metal chlorides
Direct ParentAlkaline earth metal chlorides
Alternative Parents
Substituents
  • Alkaline earth metal chloride
  • Inorganic chloride salt
  • Inorganic salt
  • Acyclic compound
Molecular FrameworkAcyclic compounds
External Descriptors
Pharmacology
IndicationFor the treatment of hypocalcemia in those conditions requiring a prompt increase in blood plasma calcium levels, for the treatment of magnesium intoxication due to overdosage of magnesium sulfate, and used to combat the deleterious effects of hyperkalemia as measured by electrocardiographic (ECG), pending correction of the increased potassium level in the extracellular fluid.
PharmacodynamicsCalcium is the fifth most abundant element in the body and the major fraction is in the bony structure. Calcium plays important physiological roles, many of which are poorly understood. It is essential for the functional integrity of the nervous and muscular systems. It is necessary for normal cardiac function and is one of the factors that operates in the mechanisms involved in the coagulation of blood.
Mechanism of actionCalcium chloride in water dissociates to provide calcium (Ca2+) and chloride (Cl-) ions. They are normal constituents of the body fluids and are dependent on various physiological mechanisms for maintenance of balance between intake and output. For hyperkalemia, the influx of calcium helps restore the normal gradient between threshold potential and resting membrane potential.
Related Articles
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
Metabolism

Approximately 80% of body calcium is excreted in the feces as insoluble salts; urinary excretion accounts for the remaining 20%.

Route of eliminationApproximately 80% of body calcium is excreted in the feces as insoluble salts; urinary excretion accounts for the remaining 20%.
Half lifeNot Available
ClearanceNot Available
ToxicityToo rapid injection may produce lowering of blood pressure and cardiac syncope. Persistent hypercalcemia from overdosage of calcium is unlikely because of rapid excretion.
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.9445
Blood Brain Barrier+0.975
Caco-2 permeable+0.6764
P-glycoprotein substrateNon-substrate0.9039
P-glycoprotein inhibitor INon-inhibitor0.9891
P-glycoprotein inhibitor IINon-inhibitor0.9866
Renal organic cation transporterNon-inhibitor0.9196
CYP450 2C9 substrateNon-substrate0.8116
CYP450 2D6 substrateNon-substrate0.717
CYP450 3A4 substrateNon-substrate0.7571
CYP450 1A2 substrateNon-inhibitor0.7506
CYP450 2C9 inhibitorNon-inhibitor0.8587
CYP450 2D6 inhibitorNon-inhibitor0.9306
CYP450 2C19 inhibitorNon-inhibitor0.8304
CYP450 3A4 inhibitorNon-inhibitor0.956
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9002
Ames testNon AMES toxic0.6808
CarcinogenicityCarcinogens 0.764
BiodegradationReady biodegradable0.6815
Rat acute toxicity1.9786 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9433
hERG inhibition (predictor II)Non-inhibitor0.9634
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
ManufacturersNot Available
Packagers
Dosage forms
FormRouteStrength
Solutionintravenous100 mg
Liquiddialysis
Powder for solutionintraocular
Solutionintraocular
Solutionirrigation
Liquid
Solutionophthalmic
Kit
Solution; kitintraocular
Liquidintravenous100 mg
Injectionintravenous100 mg/mL
Injectionintravenous; intraventricular100 mg/mL
Injectionparenteral100 mg/mL
Injection, solutionintravenous100 mg/mL
Injection, solutionintravenous20 mg/mL
Injection, solutionintravenous; intraventricular100 mg/mL
Powderdialysis12.32 g
Powderdialysis3.78 g
Powder for solutiondialysis12.9 g
Powder for solutiondialysis5.8 g
Powderdialysis6.1 g
Powderdialysis12.2 g
Powderdialysis7.45 g
Powderdialysis14.9 g
Solutionintra-arterial
Solutionintraperitoneal
Injection, solutionintraperitoneal
Solutiondialysis
Solutionoral
Solutionintracranial
Liquidophthalmic
Injection, solution, concentrateintravenous
Liquidintraperitoneal
Solutionintraperitoneal; dialysis
Liquidintraocular
Solutionintravenous
Liquidirrigation
Injection, solutionintravenous
Liquidbuccal
Spraybuccal
Solution; kitintraocular; irrigation
Emulsionintravenous
Injection, solutionintra-arterial
Solutioninstillation
Solutionintravenous; dialysis
Liquidintravenous
Injectionintravenous
Irrigantirrigation
Aerosoloral
Prices
Unit descriptionCostUnit
SureStep Test 25 Strip Box31.92USD box
Calcium chloride powder0.44USD g
Calcium chloride 10% vial0.18USD ml
Calcium chloride granules0.1USD g
Calcium chloride 10% ampul0.07USD ml
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US6077836 No1997-06-202017-06-20Us
US6248726 No1998-06-192018-06-19Us
US7084130 No2001-11-292021-11-29Us
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point782 °CNot Available
water solubility0.745 g/mL (at 20 °C)Not Available
Predicted Properties
PropertyValueSource
logP-0.57ChemAxon
pKa (Strongest Acidic)-7ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
References
Synthesis Reference

Silvano Grosso, Kenneth E. Nelson, “Method for preparing liquid feed supplements containing calcium chloride.” U.S. Patent US3962484, issued August, 1973.

US3962484
General ReferencesNot Available
External Links
ATC CodesA12AA07B05XA07G04BA03
AHFS Codes
  • 40:12.00
  • 40:34.00*
  • 92:02.00*
PDB EntriesNot Available
FDA labelNot Available
MSDSDownload (74.1 KB)
Interactions
Drug InteractionsNot Available
Food InteractionsNot Available
Comments
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Drug created on June 13, 2005 07:24 / Updated on September 26, 2016 02:13