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Identification
NameClindamycin
Accession NumberDB01190  (APRD00566)
TypeSmall Molecule
GroupsApproved
Description

Clindamycin is a semisynthetic lincosamide antibiotic that has largely replaced lincomycin due to an improved side effect profile. Clindamycin inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits. It may be bacteriostatic or bactericidal depending on the organism and drug concentration.

Structure
Thumb
Synonyms
7-CDL
7(S)-Chloro-7-deoxylincomycin
Cleocin (tn)
Clindamicina
Clindamycin
Clindamycine
Clindamycinum
Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside
External Identifiers Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Auro-clindamycincapsule300 mgoralAuro Pharma Inc2015-03-02Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Auro-clindamycincapsule150 mgoralAuro Pharma Inc2015-03-02Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ava-clindamycincapsule300 mgoralAvanstra Inc2011-08-222014-08-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ava-clindamycincapsule150 mgoralAvanstra Inc2011-08-222014-08-21Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Cleocinsuppository100 mg/1vaginalPharmacia and Upjohn Company1999-08-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocinsuppository100 mg/1vaginalU.S. Pharmaceuticals1999-08-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocincream20 mg/gvaginalPharmacia and Upjohn Company1992-08-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Hydrochloridecapsule150 mg/1oralPharmacia and Upjohn Company1970-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Hydrochloridecapsule300 mg/1oralPharmacia and Upjohn Company1970-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Hydrochloridecapsule75 mg/1oralPharmacia and Upjohn Company1970-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution6 mg/mLintramuscular; intravenousPharmacia and Upjohn Company2014-09-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintramuscular; intravenousPharmacia and Upjohn Company1972-10-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution6 mg/mLintravenousPharmacia and Upjohn Company1990-08-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintramuscular; intravenousPharmacia and Upjohn Company1972-10-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution12 mg/mLintravenousPharmacia and Upjohn Company1990-08-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintramuscular; intravenousPharmacia and Upjohn Company1972-10-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintramuscular; intravenousPharmacia and Upjohn Company2014-04-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution18 mg/mLintramuscular; intravenousPharmacia and Upjohn Company2014-09-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintramuscular; intravenousGeneral Injectables & Vaccines, Inc2012-10-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintramuscular; intravenousPharmacia and Upjohn Company1972-10-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution12 mg/mLintramuscular; intravenousPharmacia and Upjohn Company2014-09-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintramuscular; intravenousPharmacia and Upjohn Company2014-04-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintramuscular; intravenousPharmacia and Upjohn Company2014-04-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution18 mg/mLintravenousPharmacia and Upjohn Company1990-08-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Tgel10 mg/gtopicalPharmacia and Upjohn Company1987-01-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Tlotion10 mg/mLtopicalPharmacia and Upjohn Company1989-05-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Tsolution10 mg/mLtopicalPharmacia and Upjohn Company1980-06-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clinda-Tsolution1 %topicalValeant Canada Lp Valeant Canada S.E.C.2007-07-25Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindagelgel1 g/10mLtopicalOnset Dermatologics LLC2013-11-25Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycincapsule150 mgoralSanis Health Inc2013-02-13Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycincapsule300 mgoralSanis Health Inc2013-02-13Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin Hydrochloridecapsule300 mg/1oralKAISER FOUNDATION HOSPITALS2009-09-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralKAISER FOUNDATION HOSPITALS2009-09-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralGreenstone LLC1970-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralGreenstone LLC1970-05-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Injectionliquid150 mgintramuscular; intravenousFresenius Kabi Canada Ltd1995-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin Injection Sdzliquid150 mgintramuscular; intravenousSandoz Canada Incorporated2012-07-26Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin Injection USPliquid150 mgintravenousSandoz Canada Incorporated1999-01-15Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin Injection USPliquid150 mgintramuscular; intravenousSandoz Canada Incorporated1999-01-19Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin Injection, USPsolution150 mgintramuscular; intravenousAbbott Laboratories, Limited1995-12-312007-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin Injection, USPsolution150 mgintramuscular; intravenousMylan Pharmaceuticals UlcNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin IV Infusionsolution18 mgintravenousSandoz Canada Incorporated2013-12-05Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin IV Infusionsolution12 mgintravenousSandoz Canada Incorporated2013-12-05Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin IV Infusionsolution6 mgintravenousSandoz Canada IncorporatedNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycin Phosphatecream20 mg/gvaginalGreenstone LLC1992-08-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatelotion10 mg/mLtopicalGreenstone LLC1989-05-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphategel10 mg/gtopicalGreenstone LLC1987-01-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalGreenstone LLC1980-06-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphate Injection USP Liqliquid150 mgintramuscular; intravenousLyphomed, Division Of Fujisawa Canada Inc.1994-12-311996-09-10Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycine-150capsule150 mgoralPro Doc Limitee2003-12-10Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindamycine-300capsule300 mgoralPro Doc Limitee2003-12-10Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Clindessecream20 mg/gvaginalTher Rx Corporation2009-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindessecream100 mg/5gvaginalPerrigo New York Inc2015-07-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindetspad1 %topicalGlaxosmithkline Inc2002-06-10Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dalacin C 150 mgcapsule150 mgoralPfizer Canada Inc1970-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dalacin C 300 mgcapsule300 mgoralPfizer Canada Inc1995-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dalacin C Flavoured Granulespowder for solution75 mgoralPfizer Canada Inc1972-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dalacin C Phosphatesolution150 mgintramuscular; intravenousPfizer Canada Inc1973-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dalacin T 1%solution1 %topicalPfizer Canada Inc1991-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Dalacin Vaginal Cream 20 mgcream20 mgvaginalPfizer Canada Inc1994-12-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Evoclinaerosol, foam10 mg/gtopicalPrestium Pharma, Inc.2014-08-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Mylan-clindamycincapsule300 mgoralMylan Pharmaceuticals Ulc2004-09-14Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Mylan-clindamycincapsule150 mgoralMylan Pharmaceuticals Ulc2004-09-14Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Nu-clindamycincapsule300 mgoralNu Pharm IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Nu-clindamycincapsule150 mgoralNu Pharm IncNot applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
PMS-clindamycincapsule300 mgoralPharmascience Inc2007-12-18Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
PMS-clindamycincapsule150 mgoralPharmascience Inc2007-12-18Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ran-clindamycincapsule300 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ran-clindamycincapsule150 mgoralRanbaxy Pharmaceuticals Canada Inc.Not applicableNot applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ratio-clindamycin Capsules - 300mgcapsule300 mgoralRatiopharm Inc Division Of Teva Canada Limited2000-02-242010-08-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Ratio-clindamycin Capsules-150mgcapsule150 mgoralRatiopharm Inc Division Of Teva Canada Limited2000-02-242010-08-02Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Riva-clindamycincapsule150 mgoralLaboratoire Riva Inc2000-08-142013-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Riva-clindamycincapsule300 mgoralLaboratoire Riva Inc2009-08-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Riva-clindamycincapsule300 mgoralLaboratoire Riva Inc2000-08-142013-07-31Canada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Riva-clindamycincapsule150 mgoralLaboratoire Riva Inc2009-08-31Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Taro-clindamycinsolution1 %topicalTaro Pharmaceuticals Inc2005-10-03Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Teva-clindamycincapsule300 mgoralTeva Canada Limited2000-02-18Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Teva-clindamycincapsule150 mgoralTeva Canada Limited2000-02-18Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Generic Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Apo-clindamycincapsule300 mgoralApotex Inc2002-02-20Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Apo-clindamycincapsule150 mgoralApotex Inc2002-02-20Not applicableCanada 5f16b84899037e23705f146ff57e3794121879cb055f0954756d94bc690476b4
Cleocingranule, for solution75 mg/5mLoralPhysicians Total Care, Inc.2007-11-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Pediatricgranule, for solution75 mg/5mLoralPharmacia And Upjohn Company Llc1986-04-17Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintravenousPharmacia and Upjohn Company1987-10-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphateinjection, solution150 mg/mLintravenousPharmacia and Upjohn Company1987-10-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Cleocin Phosphate (0009-6582) (standalone)injection, solution150 mg/mLintravenousPharmacia and Upjohn Company1987-10-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clin-single Use Kitkitintramuscular; intravenousBurke Therapeutics, LLC2015-08-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindacin EtzkitMedimetriks Pharmaceuticals, Inc.2013-06-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindacin Etzswab10 mg/1topicalMedimetriks Pharmaceuticals, Inc.2013-06-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindacin Pswab10 mg/1topicalMedimetriks Pharmaceuticals, Inc.2011-02-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindacin Pacswab10 mg/1topicalMedimetriks Pharmaceuticals, Inc.2011-02-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamaxgel10 mg/gtopicalPharma Derm, A Division Of Nycomed Us Inc.2009-10-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamaxcream20 mg/gvaginalPHARMADERM. A division of Nycomed US Inc.2009-10-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamax Lotionsuspension10 mg/mLtopicalPharma Derm, A Division Of Nycomed Us Inc.2002-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution, concentrate150 mg/mLintravenousHospira, Inc.1987-07-24Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution150 mg/mLintramuscular; intravenousHospira, Inc.1987-07-24Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution, concentrate150 mg/mLintravenousAlvogen Inc.2016-01-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection600 mg/50mLintravenousAkorn, Inc.2013-04-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection300 mg/50mLintravenousAkorn, Inc.2013-04-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution150 mg/mLintravenousSagent Pharmaceuticals2012-05-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution150 mg/mLintramuscular; intravenousGeneral Injectables & Vaccines, Inc2010-01-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution, concentrate150 mg/mLintravenousHospira, Inc.1988-09-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution, concentrate150 mg/mLintravenousAlvogen Inc.2015-11-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution, concentrate150 mg/mLintravenousHospira, Inc.1987-07-24Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution, concentrate150 mg/mLintravenousAlvogen Inc.2015-11-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution150 mg/mLintravenousFresenius Kabi USA, LLC2009-11-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution150 mg/mLintramuscular; intravenousCardinal Health2012-05-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution150 mg/mLintramuscular; intravenousHospira, Inc.1987-07-24Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution, concentrate150 mg/mLintravenousHospira, Inc.1987-07-24Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution, concentrate150 mg/mLintravenousCardinal Health2011-06-09Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection, solution150 mg/mLintramuscular; intravenousHospira, Inc.1987-07-24Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycininjection900 mg/50mLintravenousAkorn, Inc.2013-04-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralAmerican Health Packaging2008-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralCardinal Health1989-09-20Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralREMEDYREPACK INC.2013-05-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralRanbaxy Pharmaceuticals Inc.2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralRebel Distributors Corp2001-02-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralLake Erie Medical DBA Quality Care Products LLC2010-11-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule, gelatin coated300 mg/1oralCore Pharma, Llc2004-04-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralKAISER FOUNDATION HOSPITALS2014-03-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralPreferred Pharmaceuticals, Inc.2012-01-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralNorthwind Pharmaceuticals2014-06-17Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule, gelatin coated150 mg/1oralContract Pharmacy Services Pa2010-07-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralActavis Pharma, Inc.2003-03-182016-03-31Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralProficient Rx LP2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule, gelatin coated150 mg/1oralCore Pharma, Llc2004-04-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralAidarex Pharmaceuticals LLC2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralPreferred Pharmaceuticals, Inc.2012-01-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralMajor Pharmaceuticals2009-04-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralClinical Solutions Wholesale2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralPhysicians Total Care, Inc.1998-09-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralContract Pharmacy Services Pa2010-08-09Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralActavis Pharma, Inc.2014-09-09Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralMylan Pharmaceuticals Inc.2013-05-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralProficient Rx LP2009-08-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralNorthwind Pharmaceuticals2014-06-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralMc Kesson Packaging Services Business Unit Of Mc Kesson Corporation2007-08-06Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralAidarex Pharmaceuticals LLC2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralClinical Solutions Wholesale2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralA S Medication Solutions Llc2009-08-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralLake Erie Medical DBA Quality Care Products LLC2010-11-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralMylan Pharmaceuticals Inc.2013-05-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralDIRECT RX2015-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralPhysicians Total Care, Inc.2005-04-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralMylan Institutional Inc.2000-05-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralbryant ranch prepack2003-03-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralLiberty Pharmaceuticals, Inc.2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralLake Erie Medical DBA Quality Care Products LLC2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralREMEDYREPACK INC.2011-07-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralLannett Company, Inc.2005-08-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule75 mg/1oralMylan Pharmaceuticals Inc.2013-05-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralTeva Pharmaceuticals USA Inc2005-08-092015-10-31Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralStat Rx USA2001-02-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralDIRECT RX2014-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralUnit Dose Services2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralAurobindo Pharma Limited2009-08-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralREMEDYREPACK INC.2011-04-06Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralPreferred Pharmaceuticals, Inc.2013-03-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralPd Rx Pharmaceuticals, Inc.2003-03-18Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralREMEDYREPACK INC.2014-05-13Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralbryant ranch prepack1991-07-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralLannett Company, Inc.2005-08-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralPd Rx Pharmaceuticals, Inc.2005-08-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralTeva Pharmaceuticals USA Inc1990-09-302015-11-30Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralApotheca Inc.2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralDIRECT RX2015-01-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralUnit Dose Services2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralAurobindo Pharma Limited2009-08-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralREMEDYREPACK INC.2010-12-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralPreferred Pharmaceuticals, Inc.2011-11-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralPd Rx Pharmaceuticals, Inc.1991-07-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralREMEDYREPACK INC.2014-03-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralAvera Mc Kennan Hospital2015-06-08Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralBlenheim Pharmacal, Inc.2012-11-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralREMEDYREPACK INC.2014-10-24Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralAv Pak2014-07-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule75 mg/1oralLannett Company, Inc.2005-08-12Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralKAISER FOUNDATION HOSPITALS2014-11-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralPd Rx Pharmaceuticals, Inc.1991-07-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralProficient Rx LP2003-03-182016-03-31Us 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralREMEDYREPACK INC.2013-05-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralAmerican Health Packaging2008-04-22Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralRebel Distributors Corp2001-02-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralPreferred Pharmaceuticals, Inc.2013-09-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralCardinal Health2007-08-06Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralREMEDYREPACK INC.2013-09-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralMedsource Pharmaceuticals2009-08-26Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralRanbaxy Pharmaceuticals Inc.2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralAv Pak2014-07-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule300 mg/1oralKAISER FOUNDATION HOSPITALS2014-03-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralSTAT Rx USA LLC2001-02-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralBlenheim Pharmacal, Inc.2010-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralProficient Rx LP2001-03-23Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralRed Pharm Drug Inc.2006-11-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Hydrochloridecapsule150 mg/1oralActavis Pharma, Inc.1991-07-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin In 5 Percent Dextroseinjection, solution6 mg/mLintravenousSandoz Inc2013-02-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin In 5 Percent Dextroseinjection, solution18 mg/mLintravenousSandoz Inc2014-03-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin In 5 Percent Dextroseinjection, solution12 mg/mLintravenousSandoz Inc2014-03-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin In 5 Percent Dextroseinjection, solution6 mg/mLintravenousSandoz Inc2014-03-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin In 5 Percent Dextroseinjection, solution18 mg/mLintravenousSandoz Inc2013-02-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin In 5 Percent Dextroseinjection, solution12 mg/mLintravenousSandoz Inc2013-02-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Palmitate Hydrochloridesolution75 mg/5mLoralGreenstone LLC1971-09-16Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Palmitate Hydrochloridesolution75 mg/5mLoralMarlex Pharmaceuticals Inc2015-08-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Palmitate Hydrochloridegranule, for solution75 mg/5mLoralPaddock Laboratories, LLC2010-01-21Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Palmitate Hydrochloridepowder, for solution75 mg/5mLoralAmneal Pharmaceuticals of New York, LLC2013-09-02Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Palmitate Hydrochloride (pediatric)solution75 mg/5mLoralAurobindo Pharma Limited2013-04-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Palmitate Hydrochloride (pediatric)solution75 mg/5mLoralNorth Star Rx Llc2013-04-30Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Palmitate Hydrochloride (pediatric)granule, for solution75 mg/5mLoralLyne Laboratories, Inc.2012-09-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Palmitate Hydrochloride (pediatric)granule, for solution75 mg/5mLoralRising Pharmaceuticals, Inc.2012-10-01Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphateaerosol, foam10 mg/gtopicalPerrigo New York Inc2010-03-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalPhysicians Total Care, Inc.2002-01-11Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalAv Kare, Inc.2015-09-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphategel10 mg/gtopicalLake Erie Medical DBA Quality Care Products LLC2010-01-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatecream20 mg/gvaginalE. Fougera & Co. a division of Fougera Pharmaceuticals Inc.2004-12-27Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatecream20 mg/gvaginalPhysicians Total Care, Inc.2005-05-19Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatelotion10 mg/mLtopicalE. Fougera & Co. a division of Fougera Pharmaceuticals Inc.2002-01-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatecream20 mg/gvaginalPreferred Pharmaceuticals, Inc.2012-03-29Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphategel10 mg/gtopicalE. Fougera & Co. a division of Fougera Pharmaceuticals Inc.2010-01-28Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphategel10 mg/gtopicalPreferred Pharmaceuticals, Inc.2012-07-27Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatelotion10 mg/mLtopicalPhysicians Total Care, Inc.2003-06-03Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalE. Fougera & Co. a division of Fougera Pharmaceuticals Inc.1997-06-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalPhysicians Total Care, Inc.2003-06-04Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphategel10 mg/gtopicalPhysicians Total Care, Inc.2005-04-07Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalQualitest Pharmaceuticals2015-08-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalPerrigo New York Inc2013-09-17Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalRebel Distributors Corp1997-06-05Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalVersa Pharm Incorporated2010-07-10Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphateinjection, solution150 mg/mLintramuscular; intravenousPhysicians Total Care, Inc.1997-02-27Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalActavis Pharma, Inc.2015-01-15Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalTaro Pharmaceuticals U.S.A., Inc.2004-03-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Clindamycin Phosphatesolution10 mg/mLtopicalPerrigo New York Inc2006-05-31Not applicableUs 0a2ef1ad1c84951dc1392a8bbe1f3cb241c91ed59e44ad8268635315440d978c
Over the Counter ProductsNot Available
International Brands
NameCompany
ClinimycinHayat
Dalacin CPfizer
Dalacin T Topical SolutionPfizer
ZindaclinCrawford
Brand mixtures
NameLabellerIngredients
AcanyaCoria Laboratories
BenzaclinValeant Pharmaceuticals North America LLC
Benzaclin Topical GelValeant Canada Lp Valeant Canada S.E.C.
Biacna Topical GelValeant Canada Lp Valeant Canada S.E.C.
Clindamycin - Benzoyl PeroxidePrasco Laboratories
Clindamycin and Benzoyl PeroxidePerrigo New York Inc
Clindamycin Phosphate and Benzoyl PeroxideMylan Pharmaceuticals Inc.
Clindoxyl Adv GelGlaxosmithkline Inc
Clindoxyl GelGlaxosmithkline Inc
DuacStiefel Laboratories Inc
NeuacMedimetriks Pharmaceuticals
Neuac KitMedimetriks Pharmaceuticals
OnextonValeant Pharmaceuticals North America LLC
Taro-clindamycin/benzoyl Peroxide GelTaro Pharmaceuticals Inc
VeltinStiefel Laboratories Inc
ZianaMedicis Pharmaceutical Corp
Salts
Name/CASStructureProperties
Clindamycin hydrochloride
ThumbNot applicableDBSALT001163
Clindamycin palmitate hydrochloride
ThumbNot applicableDBSALT001215
Clindamycin phosphate
24729-96-2
Thumb
  • InChI Key: UFUVLHLTWXBHGZ-KUWMELJBSA-N
  • Monoisotopic Mass: 504.146200983
  • Average Mass: 504.963
DBSALT000778
Categories
UNII3U02EL437C
CAS number18323-44-9
WeightAverage: 424.983
Monoisotopic: 424.179870573
Chemical FormulaC18H33ClN2O5S
InChI KeyInChIKey=KDLRVYVGXIQJDK-NOWPCOIGSA-N
InChI
InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9?,10-,11+,12?,13+,14-,15-,16-,18-/m1/s1
IUPAC Name
(2S,4R)-N-{2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl}-1-methyl-4-propylpyrrolidine-2-carboxamide
SMILES
CCC[C@@H]1C[C@H](N(C)C1)C(=O)NC(C(C)Cl)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O
Taxonomy
DescriptionThis compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids.
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
Sub ClassAmino acids, peptides, and analogues
Direct ParentAlpha amino acid amides
Alternative Parents
Substituents
  • Alpha-amino acid amide
  • S-glycosyl compound
  • Glycosyl compound
  • Pyrrolidine-2-carboxamide
  • Pyrrolidine carboxylic acid or derivatives
  • N-alkylpyrrolidine
  • Oxane
  • Monosaccharide
  • Saccharide
  • Pyrrolidine
  • Monothioacetal
  • Tertiary aliphatic amine
  • Tertiary amine
  • Secondary carboxylic acid amide
  • Secondary alcohol
  • Polyol
  • Carboxamide group
  • 1,2-diol
  • Oxacycle
  • Azacycle
  • Organoheterocyclic compound
  • Sulfenyl compound
  • Thioether
  • Carboxylic acid amide
  • Hydrocarbon derivative
  • Organosulfur compound
  • Organooxygen compound
  • Organonitrogen compound
  • Organochloride
  • Organohalogen compound
  • Carbonyl group
  • Amine
  • Alkyl halide
  • Alkyl chloride
  • Alcohol
  • Aliphatic heteromonocyclic compound
Molecular FrameworkAliphatic heteromonocyclic compounds
External Descriptors
Pharmacology
IndicationFor the treatment of serious infections caused by susceptible anaerobic bacteria, including Bacteroides spp., Peptostreptococcus, anaerobic streptococci, Clostridium spp., and microaerophilic streptococci. May be useful in polymicrobic infections such as intra-abdominal or pelvic infections, osteomyelitis, diabetic foot ulcers, aspiration pneumonia and dental infections. May also be used to treat MSSA and respiratory infections caused by S. pneumoniae and S. pyogenes in patients who are intolerant to other indicated antibiotics or who are infected with resistant organism. May be used vaginally to treat vaginosis caused by Gardnerella vaginosa. Clindamycin reduces the toxin producing effects of S. aureus and S. pyogenes and as such, may be particularly useful for treating necrotizing fasciitis. May be used topically to treat acne.
PharmacodynamicsClindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Mechanism of actionSystemic/vaginal clindamycin inhibits protein synthesis of bacteria by binding to the 50S ribosomal subunits of the bacteria. Specifically, it binds primarily to the 23s RNA subunit. Topical clindamycin reduces free fatty acid concentrations on the skin and suppresses the growth of Propionibacterium acnes (Corynebacterium acnes) , an anaerobe found in sebaceous glands and follicles.
AbsorptionRapidly absorbed after oral administration with peak serum concentrations observed after about 45 minutes. Absorption of an oral dose is virtually complete (90%) and the concomitant intake of food does not appreciably modify the serum concentrations; serum levels have been uniform and predictable from person to person and dose to dose. Clindamycin does not penetrate the blood brain barrier.
Volume of distributionNot Available
Protein binding92-94%
Metabolism

Hepatic

Route of eliminationApproximately 10% of the bioactivity is excreted in the urine and 3.6% in the feces; the remainder is excreted as bioinactive metabolites.
Half life2.4 hours
ClearanceNot Available
ToxicityAdverse effects include nausea (may be dose-limiting), diarrhea, pseudomembranous colitis, allergic reactions, hepatoxicity, transient neutropenia and eosinophilia and agranulocytosis. Pseudomembranous colitis occurs in 0.01 - 10% of patients and occurs more commonly than with other antibiotics. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Affected organisms
  • Enteric bacteria and other eubacteria
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
ADMET
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.8143
Blood Brain Barrier-0.9697
Caco-2 permeable-0.8236
P-glycoprotein substrateSubstrate0.7653
P-glycoprotein inhibitor INon-inhibitor0.7311
P-glycoprotein inhibitor IIInhibitor0.7894
Renal organic cation transporterNon-inhibitor0.8784
CYP450 2C9 substrateNon-substrate0.8214
CYP450 2D6 substrateNon-substrate0.9116
CYP450 3A4 substrateSubstrate0.6762
CYP450 1A2 substrateNon-inhibitor0.9045
CYP450 2C9 inhibitorNon-inhibitor0.9071
CYP450 2D6 inhibitorNon-inhibitor0.9231
CYP450 2C19 inhibitorNon-inhibitor0.9025
CYP450 3A4 inhibitorNon-inhibitor0.8876
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9107
Ames testNon AMES toxic0.6967
CarcinogenicityNon-carcinogens0.9172
BiodegradationNot ready biodegradable0.994
Rat acute toxicity2.3192 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9887
hERG inhibition (predictor II)Non-inhibitor0.59
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )
Pharmacoeconomics
ManufacturersNot Available
Packagers
Dosage forms
FormRouteStrength
Creamvaginal20 mg/g
Suppositoryvaginal100 mg/1
Capsuleoral150 mg/1
Capsuleoral300 mg/1
Capsuleoral75 mg/1
Injection, solutionintramuscular; intravenous12 mg/mL
Injection, solutionintramuscular; intravenous150 mg/mL
Injection, solutionintramuscular; intravenous18 mg/mL
Injection, solutionintramuscular; intravenous6 mg/mL
Injection, solutionintravenous12 mg/mL
Injection, solutionintravenous150 mg/mL
Injection, solutionintravenous18 mg/mL
Injection, solutionintravenous6 mg/mL
Geltopical10 mg/g
Lotiontopical10 mg/mL
Solutiontopical10 mg/mL
Kitintramuscular; intravenous
Kit
Swabtopical10 mg/1
Geltopical1 g/10mL
Suspensiontopical10 mg/mL
Injectionintravenous300 mg/50mL
Injectionintravenous600 mg/50mL
Injectionintravenous900 mg/50mL
Injection, solution, concentrateintravenous150 mg/mL
Capsule, gelatin coatedoral150 mg/1
Capsule, gelatin coatedoral300 mg/1
Liquidintramuscular; intravenous150 mg
Liquidintravenous150 mg
Solutionintravenous12 mg
Solutionintravenous18 mg
Solutionintravenous6 mg
Powder, for solutionoral75 mg/5mL
Solutionoral75 mg/5mL
Granule, for solutionoral75 mg/5mL
Kit
Creamvaginal100 mg/5g
Padtopical1 %
Capsuleoral300 mg
Powder for solutionoral75 mg
Solutionintramuscular; intravenous150 mg
Solutiontopical1 %
Creamvaginal20 mg
Aerosol, foamtopical10 mg/g
Kittopical
Capsuleoral150 mg
Geltopical
Prices
Unit descriptionCostUnit
Clindagel 1% Gel 75ml Bottle324.48USD bottle
Evoclin 1% Foam 100 gm Can306.79USD can
Clindamycin Phosphate 1% Foam 100 gm Can286.04USD can
Evoclin 1% Foam 50 gm Can207.67USD can
Clindagel 1% Gel 40ml Bottle203.42USD bottle
Clindamycin Phosphate 1% Foam 50 gm Can186.9USD can
Clindamycin Phos-Benzoyl Perox 1-5% Gel 50 gm Jar176.42USD jar
Cleocin-T 1% Gel 60 gm Tube112.84USD tube
Cleocin-T 1% Lotion 60ml Bottle86.09USD bottle
Cleocin-T 60 1% Swab Box82.6USD box
Cleocin 2% Cream 40 gm Tube81.56USD tube
Cleocin 3 100 mg Suppository Box80.05USD box
Cleocin 75 mg/5ml Solution 100ml Bottle78.7USD bottle
Clindamycin hcl crystals74.9USD g
Clindamycin Phosphate 1% Gel 60 gm Tube71.42USD tube
Cleocin-T 1% Solution 60ml Bottle69.29USD bottle
Cleocin-T 1% Gel 30 gm Tube62.98USD tube
Clindamycin Phosphate 2% Cream 40 gm Tube54.99USD tube
Clindamycin Phosphate 60 1% Swab Box47.74USD box
Clindamycin Phosphate 1% Lotion 60ml Bottle46.92USD bottle
Clindesse 2% vaginal cream39.08USD g
Clindamycin Phosphate 1% Gel 30 gm Tube33.41USD tube
Clindamycin Phosphate 1% Solution 60ml Bottle24.07USD bottle
Clindamycin phosphate powdr21.42USD g
Clindamycin Phosphate 1% Solution 30ml Bottle14.99USD bottle
Cleocin hcl 300 mg capsule9.11USD capsule
Clindamycin phos crystals7.73USD g
Evoclin 1% foam4.9USD g
Clindagel 1% gel4.89USD ml
Cleocin 150 mg capsule4.66USD capsule
Dalacin C Phosphate 150 mg/ml4.53USD ml
Clindamycin hcl 300 mg capsule3.98USD capsule
Clindamycin phosphate 1% foam3.59USD g
Clindamycin 150 mg/ml3.48USD ml
Clindamycin (60 & 120 Ml) 150 mg/ml3.41USD ml
Cleocin hcl 150 mg capsule2.79USD capsule
Cleocin hcl 75 mg capsule2.28USD capsule
Dalacin C 300 mg Capsule2.12USD capsule
Cleocin 2% vaginal cream1.97USD g
Clindamycin 150 mg/ml addvan1.97USD ml
Cleocin phos 150 mg/ml vial1.91USD ml
Cleocin t 1% gel1.81USD g
Clindamycin ph 300 mg/2 ml vial1.74USD ml
Clindamax 2% vaginal cream1.37USD g
Clindamycin 2% vaginal cream1.27USD g
Clindamycin hcl 150 mg capsule1.21USD capsule
Clindets 1% pledgets1.1USD each
Dalacin C 150 mg Capsule1.06USD capsule
Apo-Clindamycin 300 mg Capsule1.02USD capsule
Mylan-Clindamycin 300 mg Capsule1.02USD capsule
Novo-Clindamycin 300 mg Capsule1.02USD capsule
Clindamycin ph 9 g/60 ml vial0.93USD ml
Apo-Clindamycin 150 mg Capsule0.51USD capsule
Mylan-Clindamycin 150 mg Capsule0.51USD capsule
Novo-Clindamycin 150 mg Capsule0.51USD capsule
Clinda-derm 1% solution0.4USD ml
Cleocin 900 mg-d5w-galaxy0.37USD ml
Cleocin 600 mg-d5w-galaxy0.3USD ml
Dalacin C Palmitate 15 mg/ml Solution0.14USD ml
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
CountryPatent NumberApprovedExpires (estimated)
United States52663291993-11-302010-11-30
United States73747472006-08-092026-08-09
Properties
StateSolid
Experimental Properties
PropertyValueSource
melting point142 [HCl salt]Not Available
water solubility30.6 mg/LNot Available
logP2.16HANSCH,C ET AL. (1995)
Predicted Properties
PropertyValueSource
Water Solubility3.1 mg/mLALOGPS
logP1.76ALOGPS
logP1.04ChemAxon
logS-2.1ALOGPS
pKa (Strongest Acidic)12.16ChemAxon
pKa (Strongest Basic)7.55ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count4ChemAxon
Polar Surface Area102.26 Å2ChemAxon
Rotatable Bond Count7ChemAxon
Refractivity105.72 m3·mol-1ChemAxon
Polarizability44.49 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon
Spectra
Mass Spec (NIST)Not Available
SpectraNot Available
References
Synthesis Reference

Donald E. Ayer, Carl A. Schlagel, Gordon L. Flynn, “Topical clindamycin preparations.” U.S. Patent US4018918, issued January, 1971.

US4018918
General References
  1. Daum RS: Clinical practice. Skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. N Engl J Med. 2007 Jul 26;357(4):380-90. Pubmed
  2. Klempner MS, Styrt B: Clindamycin uptake by human neutrophils. J Infect Dis. 1981 Nov;144(5):472-9. Pubmed
  3. Lamont RF: Can antibiotics prevent preterm birth—the pro and con debate. BJOG. 2005 Mar;112 Suppl 1:67-73. Pubmed
  4. Plaisance KI, Drusano GL, Forrest A, Townsend RJ, Standiford HC: Pharmacokinetic evaluation of two dosage regimens of clindamycin phosphate. Antimicrob Agents Chemother. 1989 May;33(5):618-20. Pubmed
External Links
ATC CodesD10AF01G01AA10J01FF01
AHFS Codes
  • 08:12.28.20
  • 84:04.04
PDB EntriesNot Available
FDA labelDownload (151 KB)
MSDSDownload (72.8 KB)
Interactions
Drug Interactions
Drug
Atracurium besylateClindamycin may increase the neuromuscular blocking activities of Atracurium besylate.
Cisatracurium besylateClindamycin may increase the neuromuscular blocking activities of Cisatracurium besylate.
ErythromycinThe therapeutic efficacy of Clindamycin can be decreased when used in combination with Erythromycin.
KaolinKaolin can cause a decrease in the absorption of Clindamycin resulting in a reduced serum concentration and potentially a decrease in efficacy.
MecamylamineClindamycin may increase the neuromuscular blocking activities of Mecamylamine.
PancuroniumClindamycin may increase the neuromuscular blocking activities of Pancuronium.
RocuroniumClindamycin may increase the neuromuscular blocking activities of Rocuronium.
Sodium picosulfateThe therapeutic efficacy of Sodium picosulfate can be decreased when used in combination with Clindamycin.
SuccinylcholineClindamycin may increase the neuromuscular blocking activities of Succinylcholine.
SulfisoxazoleThe therapeutic efficacy of Clindamycin can be decreased when used in combination with Sulfisoxazole.
VecuroniumClindamycin may increase the neuromuscular blocking activities of Vecuronium.
Food Interactions
  • Take with food.

Targets

1. 50S ribosomal protein L10

Kind: Protein

Organism: Shigella flexneri

Pharmacological action: yes

Actions: inhibitor

Components

Name UniProt ID Details
50S ribosomal protein L10 P0A7J6 Details

References:

  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Pubmed
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. Pubmed
  3. Schlunzen F, Zarivach R, Harms J, Bashan A, Tocilj A, Albrecht R, Yonath A, Franceschi F: Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature. 2001 Oct 25;413(6858):814-21. Pubmed

2. 23S rRNA

Kind: Nucleotide

Organism: Enteric bacteria and other eubacteria

Pharmacological action: yes

Actions: inhibitor

Components

Name UniProt ID Details

References:

  1. Schlunzen F, Zarivach R, Harms J, Bashan A, Tocilj A, Albrecht R, Yonath A, Franceschi F: Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature. 2001 Oct 25;413(6858):814-21. Pubmed

Enzymes

1. Cytochrome P450 3A4

Kind: Protein

Organism: Human

Pharmacological action: unknown

Actions: substrate inhibitor

Components

Name UniProt ID Details
Cytochrome P450 3A4 P08684 Details

References:

  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. Pubmed

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Drug created on June 13, 2005 07:24 / Updated on September 16, 2013 17:13