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Displaying drugs 76 - 100 of 2005 in total
DrugBank ID Name Weight StructureCategoriesTherapeutic Indication
DB09160
127455-27-0
Technetium Tc-99m tetrofosmin898.86

C36H84O10P4Tc
ThumbDiagnostic Radiopharmaceuticals / Technetium (99Mtc) Compounds / Cardiovascular System / Technetium (99mTc) compoundsNot Annotated
DB09296
1258226-87-7
Ombitasvir894.127

C50H67N7O8
ThumbAntiviral Agents / Direct Acting Antivirals / Antivirals for Systemic Use / P-glycoprotein/ABCB1 Substrates / Antiinfectives for Systemic Use / Cytochrome P-450 CYP2C8 Substrates / Other antivirals / Other antiviralsWhen used within the fixed dose combination product of paritaprevir/ombitasvir/ritonavir (Technivie), ombitasvir is indicated in combination with r...
DB00483
65-29-2
Gallamine Triethiodide891.5291

C30H60I3N3O3
ThumbQuaternary Ammonium Compounds / Onium Compounds / Ammonium Compounds / Nitrogen Compounds / Cholinergic Antagonists / Neuromuscular Blocking Agents / Neuromuscular Agents / Nicotinic Antagonists / Neuromuscular Nondepolarizing Agents / Cholinergic Agents / Cholinesterase Inhibitors / Peripheral Nervous System Agents / Neurotransmitter Agents / Organic Chemicals / Inorganic Chemicals / Amines / Physiological Effects of Drugs / Pharmacologic Actions / Chemical Actions and Uses / Molecular Mechanisms of Pharmacological ActionFor use as adjuncts to anesthesia to induce skeletal muscle relaxation and to facilitate the management of patients undergoing mechanical ventilation
DB09027
1256388-51-8
Ledipasvir888.9999

C49H54F2N8O6
ThumbAntiviral Agents / Direct Acting Antivirals / Antivirals for Systemic Use / Anti-Infective Agents / Antiinfectives for Systemic Use / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Other antiviralsLedipasvir in combination with sofosbuvir, or in combination with sofosbuvir and ribavirin, is indicated for the treatment of chronic hepatitis C (...
DB11613
1377049-84-7
Velpatasvir883.019

C49H54N8O8
ThumbNot AnnotatedUsed together with sofosbuvir in the treatment of hepatitis C infection of all six major genotypes.
DB11574
1370468-36-2
Elbasvir882.035

C49H55N9O7
ThumbBCRP/ABCG2 Inhibitors / P-glycoprotein/ABCB1 Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoproteinElbasvir, when used in combination with grazoprevir as the combination product Zepatier, is indicated for use with or without ribavirin for the tr...
DB01201
61379-65-5
Rifapentine877.0307

C47H64N4O12
ThumbAntitubercular Agents / Antibiotics, Antitubercular / Leprostatic Agents / Drugs for Treatment of Tuberculosis / Antimycobacterials / Cytochrome P-450 CYP2D6 Inducers / Cytochrome P-450 CYP2C9 Inducers / Cytochrome P-450 CYP2C8 Inducers / Cytochrome P-450 CYP3A Inducers / Combined Inducers of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP3A4 Inducers (strong) / Cytochrome P-450 CYP2C9 Inducers (strong) / Cytochrome P-450 CYP2C8 Inducers (strong) / Anti-Infective Agents / Therapeutic Uses / Pharmacologic Actions / Anti-Bacterial Agents / Antiinfectives for Systemic Use / Chemical Actions and Uses / AntibioticsFor the treatment of pulmonary tuberculosis.
DB11581
1257044-40-8
Venetoclax868.45

C45H50ClN7O7S
ThumbBCRP/ABCG2 Substrates / Cytochrome P-450 CYP3A4 Substrates / P-glycoprotein/ABCB1 SubstratesFor the treatment of patients with chronic lymphocytic leukemia (CLL) with 17p deletion, as detected by an FDA approved test, who have received at ...
DB09146
20344-49-4
Sucroferric Oxyhydroxide866.546

C12H29Fe5Na2O23
ThumbAntianemic Preparations / Iron Preparations / Drugs for Treatment of Hyperkalemia and Hyperphosphatemia / Iron Trivalent, Oral Preparations / Blood and Blood Forming Organs / Iron trivalent, oral preparations / Drugs for treatment of hyperkalemia and hyperphosphatemiaNot Annotated
DB06783
14038-43-8
Prussian blue859.239

C18Fe7N18
ThumbSpecialty Uses of Chemicals / Protective Agents / Antidotes / Coloring Agents / Physiological Effects of Drugs / Pharmacologic Actions / Chemical Actions and Uses / AntidotesNot Annotated
DB01229
33069-62-4
Paclitaxel853.9061

C47H51NO14
ThumbAlbumins / Cycloparaffins / Hydrocarbons, Alicyclic / Terpenes / Diterpenes / Taxoids / Cyclodecanes / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2C8 Substrates / BSEP/ABCB11 Inhibitors / Taxane Derivatives / CYP3A4 Inducers (Weak) / Paclitaxel / Macrocyclic Compounds / Antineoplastic Agents / Immunosuppressive Agents / Cytochrome P-450 CYP3A Inducers / Antimitotic Agents / Mitosis Modulators / Antineoplastic Agents, Phytogenic / Tubulin Modulators / Antineoplastic and Immunomodulating Agents / BCRP/ABCG2 Substrates / P-glycoprotein/ABCB1 Inhibitors / P-glycoprotein/ABCB1 Substrates / Myelosuppressive Agents / Combined Inducers of CYP3A4 and P-glycoprotein / Proteins / Amino Acids, Peptides, and Proteins / Cytochrome P-450 CYP3A Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP3A4 Substrates / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Polycyclic Compounds / Organic Chemicals / Hydrocarbons, Cyclic / Hydrocarbons / TaxanesUsed in the treatment of Kaposi's sarcoma and cancer of the lung, ovarian, and breast. Abraxane® is specfically indicated for the treatment of meta...
DB00615
72559-06-9
Rifabutin847.0047

C46H62N4O11
ThumbPharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Anti-Infective Agents / Macrocyclic Compounds / Polycyclic Compounds / Anti-Bacterial Agents / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds / Heterocyclic Compounds with 4 or More Rings / Organic Chemicals / Cytochrome P-450 CYP3A Inducers / Amides / Lactams / Antitubercular Agents / Antibiotics, Antitubercular / Rifamycins / Lactams, Macrocyclic / Antiinfectives for Systemic Use / Drugs for Treatment of Tuberculosis / Antimycobacterials / Cytochrome P-450 CYP1A2 Substrates / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 CYP3A4 Inducers (strong) / Combined Inducers of CYP3A4 and P-glycoprotein / AntibioticsFor the prevention of disseminated <i>Mycobacterium avium</i> complex (MAC) disease in patients with advanced HIV infection.
DB00778
80214-83-1
Roxithromycin837.0465

C41H76N2O15
ThumbCytochrome P-450 CYP1A2 Inhibitors / Erythromycin / Cytochrome P-450 CYP2B6 Inhibitors / Macrocyclic Compounds / Polycyclic Compounds / Organic Chemicals / Polyketides / Lactones / Anti-Infective Agents / Anti-Bacterial Agents / Macrolides / Antibacterials for Systemic Use / Antiinfectives for Systemic Use / Macrolides, Lincosamides and Streptogramins / Therapeutic Uses / Cytochrome P-450 CYP3A Inhibitors / Cytochrome P-450 CYP3A4 Substrates / Combined Inhibitors of CYP3A4 and P-glycoprotein / Pharmacologic Actions / Chemical Actions and Uses / MacrolidesUsed to treat respiratory tract, urinary and soft tissue infections.
DB06772
183133-96-2
Cabazitaxel835.9324

C45H57NO14
ThumbTaxoids / Cytochrome P-450 CYP2C8 Substrates / BCRP/ABCG2 Inhibitors / P-glycoprotein/ABCB1 Inhibitors / P-glycoprotein/ABCB1 Substrates / Immunosuppressive Agents / Myelosuppressive Agents / Taxane Derivatives / Combined Inhibitors of CYP3A4 and P-glycoprotein / Antineoplastic and Immunomodulating Agents / Cytochrome P-450 CYP3A4 Substrates / Antineoplastic Agents / TaxanesFor treatment of patients with hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen.
DB00954
62013-04-1
Dirithromycin835.086

C42H78N2O14
ThumbAnti-Bacterial Agents / Macrolides / Macrolides, Lincosamides and Streptogramins / Anti-Infective Agents / Antibacterials for Systemic Use / Antiinfectives for Systemic Use / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / MacrolidesFor the treatment of the following mild-to-moderate infections caused by susceptible strains of microorganisms: acute bacterial exacerbations of ch...
DB01321
16846-24-5
Josamycin827.995

C42H69NO15
ThumbMacrolides / Polyketides / Lactones / Macrolides, Lincosamides and Streptogramins / Anti-Bacterial Agents / Antibacterials for Systemic Use / Macrocyclic Compounds / Polycyclic Compounds / Anti-Infective Agents / Cytochrome P-450 CYP3A Inhibitors / Antiinfectives for Systemic Use / Combined Inhibitors of CYP3A4 and P-glycoprotein / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Organic Chemicals / MacrolidesFor the treatment of bacterial infections.
DB00541
57-22-7
Vincristine824.9576

C46H56N4O10
ThumbAlkaloids / Secologanin Tryptamine Alkaloids / Indole Alkaloids / Indoles / Vinca Alkaloids / Antimitotic Agents / Mitosis Modulators / Antineoplastic Agents, Phytogenic / Tubulin Modulators / Vinca Alkaloids and Analogues / P-glycoprotein/ABCB1 Inducers / P-glycoprotein/ABCB1 Inhibitors / BCRP/ABCG2 Substrates / Combined Inducers of CYP3A4 and P-glycoprotein / Cytochrome P-450 CYP3A Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoprotein / Antineoplastic Agents / Immunosuppressive Agents / Antineoplastic and Immunomodulating Agents / Heterocyclic Compounds, 2-Ring / Cytochrome P-450 CYP3A4 Substrates / P-glycoprotein/ABCB1 Substrates / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Heterocyclic Compounds / Vinca alkaloids and analoguesTreatment of acute lymphocytic leukemia (ALL), Hodgkin lymphoma, non-Hodgkin lymphomas, Wilms' tumor, neuroblastoma, rhabdomyosarcoma. Liposomal vi...
DB01045
13292-46-1
Rifampicin822.9402

C43H58N4O12
ThumbHeterocyclic Compounds with 4 or More Rings / Cytochrome P-450 Enzyme Inducers / Lactams / Rifamycins / Lactams, Macrocyclic / Cytochrome P-450 CYP2A6 Substrates / Cytochrome P-450 CYP2A6 Inhibitors / Cytochrome P-450 CYP2A6 Inducers / Cytochrome P-450 CYP2B6 Inducers (strong) / Cytochrome P-450 CYP2E1 Inducers / Cytochrome P-450 CYP2C9 Substrates / Cytochrome P-450 CYP2C19 Inducers (strong) / BSEP/ABCB11 Inhibitors / CYP1A2 Inducers (Strong) / Antitubercular Agents / Leprostatic Agents / Antibiotics, Antitubercular / Drugs for Treatment of Tuberculosis / Antimycobacterials / Cytochrome P-450 CYP2C9 Inducers (strong) / Cytochrome P-450 CYP2C8 Inducers (strong) / Cytochrome P-450 CYP3A4 Inducers (strong) / Macrocyclic Compounds / Nucleic Acid Synthesis Inhibitors / Cytochrome P-450 CYP2C8 Substrates / Metabolic Side Effects of Drugs and Substances / Drug-Related Side Effects and Adverse Reactions / Chemically-Induced Disorders / Cytochrome P-450 CYP3A Inducers / Cytochrome P-450 CYP1A2 Inducers / Cytochrome P-450 CYP2C8 Inhibitors / Cytochrome P-450 CYP2B6 Inducers / Cytochrome P-450 CYP2C9 Inducers / Cytochrome P-450 CYP2C19 Inducers / Cytochrome P-450 CYP2C8 Inducers / P-glycoprotein/ABCB1 Inducers / Combined Inducers of CYP3A4 and P-glycoprotein / Heterocyclic Compounds, 1-Ring / Heterocyclic Compounds / Enzyme Inhibitors / P-glycoprotein/ABCB1 Inhibitors / Anti-Infective Agents / Polycyclic Compounds / Anti-Bacterial Agents / Organic Chemicals / Antiinfectives for Systemic Use / Combined Inhibitors of CYP3A4 and P-glycoprotein / P-glycoprotein/ABCB1 Substrates / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Amides / Cytochrome P-450 CYP3A4 Substrates / Combinations of drugs for treatment of tuberculosis / Combinations of drugs for treatment of tuberculosis / Antibiotics / Combinations of drugs for treatment of tuberculosisFor the treatment of Tuberculosis and Tuberculosis-related mycobacterial infections.
DB01362
66108-95-0
Iohexol821.1379

C19H26I3N3O9
ThumbSpecialty Uses of Chemicals / Carboxylic Acids / Hydrocarbons, Aromatic / Benzene Derivatives / Diagnostic Uses of Chemicals / Contrast Media / Benzoates / Acids, Carbocyclic / Triiodobenzoic Acids / Iodobenzoates / X-Ray Contrast Media, Iodinated / Watersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / Iodinated Contrast Agents / Organic Chemicals / Hydrocarbons, Cyclic / Hydrocarbons / Pharmacologic Actions / Chemical Actions and Uses / Watersoluble, nephrotropic, low osmolar X-ray contrast mediaIohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
DB01361
2751-09-9
Troleandomycin813.9684

C41H67NO15
ThumbAnti-Bacterial Agents / Macrolides / Polyketides / Lactones / Cytochrome P-450 CYP2C8 Inhibitors / Oleandomycin / Antibacterials for Systemic Use / Macrolides, Lincosamides and Streptogramins / Cytochrome P-450 CYP2A6 Inhibitors / Macrocyclic Compounds / Polycyclic Compounds / Cytochrome P-450 CYP3A Inhibitors / Anti-Infective Agents / Cytochrome P-450 CYP2C19 Inhibitors / Antiinfectives for Systemic Use / P-glycoprotein/ABCB1 Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoprotein / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Organic Chemicals / Cytochrome P-450 CYP3A4 Substrates / MacrolidesFor the treatment of Pneumococcal pneumonia due to susceptible strains and group A beta-hemolytic streptococcal infections of the upper respiratory...
DB00976
191114-48-4
Telithromycin812.018

C43H65N5O10
ThumbMacrolides / Protein Synthesis Inhibitors / RNA, Ribosomal, 23S / Macrolides, Lincosamides and Streptogramins / Cytochrome P-450 CYP3A4 Inhibitors (strong) / Moderate Risk QTc-Prolonging Agents / Ketolides / Anti-Bacterial Agents / Antibacterials for Systemic Use / Antiinfectives for Systemic Use / Cytochrome P-450 CYP1A2 Substrates / Anti-Infective Agents / Cytochrome P-450 CYP3A4 Substrates / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP3A Inhibitors / Combined Inhibitors of CYP3A4 and P-glycoprotein / MacrolidesFor the treatment of <i>Pneumococcal</i> infection, acute sinusitis, acute bacterial tonsillitis, acute bronchitis and bronchiolitis, lower respira...
DB00570
865-21-4
Vinblastine810.9741

C46H58N4O9
ThumbAntineoplastic Agents / Immunosuppressive Agents / Alkaloids / Secologanin Tryptamine Alkaloids / Indole Alkaloids / Indoles / Vinca Alkaloids / Antimitotic Agents / Mitosis Modulators / Antineoplastic Agents, Phytogenic / Tubulin Modulators / Cytochrome P-450 CYP2D6 Inhibitors / Cytochrome P-450 CYP3A Inhibitors / Antineoplastic and Immunomodulating Agents / Vinca Alkaloids and Analogues / OCT2 Substrates / BSEP/ABCB11 Inhibitors / P-glycoprotein/ABCB1 Inducers / P-glycoprotein/ABCB1 Inhibitors / P-glycoprotein/ABCB1 Substrates / Myelosuppressive Agents / Combined Inducers of CYP3A4 and P-glycoprotein / Combined Inhibitors of CYP3A4 and P-glycoprotein / CYP2D6 Inhibitors (Weak) / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Heterocyclic Compounds / Heterocyclic Compounds, 2-Ring / Cytochrome P-450 CYP2D6 Substrates / Cytochrome P-450 CYP3A4 Substrates / Vinca alkaloids and analoguesFor treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosi...
DB00337
137071-32-0
Pimecrolimus810.46

C43H68ClNO11
ThumbImmunologic Factors / Dermatologic Agents / Calcineurin Inhibitors / Peptidylprolyl Isomerase, antagonists & inhibitors / Agents for Dermatitis, Excluding Corticosteroids / Analgesics, Non-Narcotic / Sensory System Agents / Antirheumatic Agents / Anti-Inflammatory Agents / Anti-Inflammatory Agents, Non-Steroidal / Immunosuppressive Agents / Dermatologicals / Peripheral Nervous System Agents / Central Nervous System Agents / Cytochrome P-450 CYP3A4 Substrates / Enzyme Inhibitors / Physiological Effects of Drugs / Analgesics / Molecular Mechanisms of Pharmacological Action / Pharmacologic Actions / Chemical Actions and Uses / Therapeutic Uses / Agents for dermatitis, excluding corticosteroidsFor treatment of mild to moderate atopic dermatitis.
DB01248
114977-28-5
Docetaxel807.8792

C43H53NO14
ThumbAntimitotic Agents / Mitosis Modulators / Molecular Mechanisms of Pharmacological Action / Antineoplastic Agents / Therapeutic Uses / Tubulin Modulators / Taxoids / Antineoplastic and Immunomodulating Agents / Cytochrome P-450 CYP3A4 Substrates / Cytochrome P-450 CYP3A Inhibitors / BCRP/ABCG2 Substrates / P-glycoprotein/ABCB1 Substrates / Combined Inhibitors of CYP3A4 and P-glycoprotein / Immunosuppressive Agents / Myelosuppressive Agents / Taxane Derivatives / Chemical Actions and Uses / Pharmacologic Actions / TaxanesFor the treatment of patients with locally advanced or metastatic breast cancer after failure of prior chemotherapy. Also used as a single agent in...
DB09134
87771-40-2
Ioversol807.115

C18H24I3N3O9
ThumbWatersoluble, Nephrotropic, Low Osmolar X-Ray Contrast Media / Iodinated Contrast Agents / X-Ray Contrast Media, Iodinated / Specialty Uses of Chemicals / Diagnostic Uses of Chemicals / Contrast Media / Pharmacologic Actions / Chemical Actions and Uses / Watersoluble, nephrotropic, low osmolar X-ray contrast mediaOptiray 350 is indicated in adults for peripheral and coronary arteriography and left ventriculography. Optiray 350 is also indicated for contrast ...
Displaying drugs 76 - 100 of 2005 in total