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Deoxyuridine monophosphate

Experimental
Matched Synonyms: … Deoxyuridine 5'-phosphate ... 2'-Deoxyuridine 5'-phosphate ... 2'-deoxyuridine 5'-monophosphate …
Matched Name: … Deoxyuridine monophosphate …

Deoxyuridine-5'-Triphosphate

Experimental
Matched Name: … Deoxyuridine-5'-Triphosphate …

Deoxyuridine-5'-Diphosphate

Experimental
Matched Name: … Deoxyuridine-5'-Diphosphate …

2'-Deoxyuridine

2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. [PubChem]
Experimental
Matched Name: … 2'-Deoxyuridine …
Matched Description: … 2'-Deoxyuridine. ... An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. ... Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and …

2'-Deoxyuridine 3'-Monophosphate

Experimental
Matched Name: … 2'-Deoxyuridine 3'-Monophosphate …

5-Iodo-2'-Deoxyuridine-5'-Monophosphate

Experimental
Matched Name: … 5-Iodo-2'-Deoxyuridine-5'-Monophosphate …

3,4-Dihydro-2'-deoxyuridine-5'-monophosphate

Experimental
Matched Name: … 3,4-Dihydro-2'-deoxyuridine-5'-monophosphate …

5-Bromo-2'-deoxyuridine 5'-(dihydrogen phosphate)

Experimental
Matched Name: … 5-Bromo-2'-deoxyuridine 5'-(dihydrogen phosphate) …

2'-fluoro-2'-deoxyuridine 3'-monophosphate

Experimental
Matched Name: … 2'-fluoro-2'-deoxyuridine 3'-monophosphate …

5-fluoro-2'-deoxyuridine-5'-monophosphate

Experimental
Matched Name: … 5-fluoro-2'-deoxyuridine-5'-monophosphate …

2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate

Experimental
Matched Name: … 2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate …

2'-deoxyuridine 5'-alpha,beta-imido-diphosphate

Experimental
Matched Name: … 2'-deoxyuridine 5'-alpha,beta-imido-diphosphate …

Trifluridine

Trifluridine is a fluorinated pyrimidine nucleoside that is structurally related to idoxuridine . It is an active antiviral agent in ophthalmic solutions used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus. It displays effective antiviral activity against Herpes simplex virus type 1...
Approved
Investigational
Matched Synonyms: … 5-(Trifluoromethyl)deoxyuridine ... 5-Trifluoromethyl-2-deoxyuridine …

Brivudine

Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Approved
Investigational
Matched Synonyms: … (E)-5-(2-Bromovinyl)-deoxyuridine …
Matched Categories: … Deoxyuridine …

Edoxudine

Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. The obtained product is an antiviral ointment. The activity of edoxudine against herpes simplex virus was first recognized in 1967. It was later recognized...
Approved
Investigational
Withdrawn
Matched Synonyms: … 5-Ethyl-2'-deoxyuridine …

Idoxuridine

An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Approved
Investigational
Matched Synonyms: … (+)-5-Iodo-2'-deoxyuridine ... 5-iodo-2'-deoxyuridine …
Matched Description: … An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent. …
Matched Categories: … Deoxyuridine …

Floxuridine

An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for...
Approved
Matched Synonyms: … 5-fluoro-2'-deoxyuridine ... beta-5-Fluoro-2'-deoxyuridine …
Matched Categories: … Deoxyuridine …

Doxifluridine

Doxifluridine has been investigated for the treatment of Stomach Cancer.
Investigational
Matched Synonyms: … 5-fluoro-5'-deoxyuridine …
Matched Categories: … Deoxyuridine …

Zebularine

A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo.
Experimental
Matched Synonyms: … 4-deoxyuridine …

Capecitabine

Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational

Tegafur-uracil

Tegafur-uracil is an anti-tumor compound containing tegafur (1-(2-tetrahydrofuryl)-5-fluorouracil) and uracil in a molar ratio of 1:4. It was developed as an anti-cancer therapy by Taiho Pharmaceutical Co Ltd. It is approved in different countries but it is not yet approved by the FDA, Health Canada or EMA.
Approved
Investigational

Uridine triacetate

Uridine triacetate, formerly known as vistonuridine, is an orally active prodrug of the naturally occurring nucleoside uridine. It is used for the treatment of hereditary orotic aciduria (Xuriden), or for the emergency treatment of fluorouracil or capecitabine overdose or toxicity (Vistogard). It is provided in the prodrug form as uridine...
Approved
Investigational
Matched Description: … It reduces toxicity and cell-death associated with two cytotoxic intermediates: 5-fluoro-2'-deoxyuridine …

Broxuridine

Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.
Investigational
Matched Categories: … Deoxyuridine …

Thymectacin

Thymectacin, a phosphoramidate derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine, is a novel small molecule anticancer agent. Thymectacin is selectively active against tumor cells expressing high levels of thymidylate synthase (TS), a critical enzyme in DNA biosynthesis. Thymectacin was as efficacious as irinotecan, a drug recently approved for the treatment of 5-fluorouracil-resistant colon cancer.
Investigational
Matched Description: … Thymectacin, a phosphoramidate derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine, is a novel small molecule …
Matched Categories: … Deoxyuridine …
Displaying all 24 drugs