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Displaying drugs 26 - 50 of 4223 in total

ALX-009

Investigational
Matched Synonyms: … Hypothiocyanite and lactoferrin …

Sodium fluorophosphate

Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Approved
Matched Mixtures name: … Mentadent Specialty Whitening Toothpaste and Polishing ... Hawaiian Airline EC with Colgate Toothbrush and Sun ... White Glo Charcoal Sensitive …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Hapee Fresh and Cool White 100 ... Colgate 10g and Toothbrush Dental Kit ... 100 toothpast e Night …

Antihemophilic factor human

Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is a non-recombinant, lyophilized concentrate of coagulation factor VIII, an endogenous protein and essential component of the coagulation cascade. Antihemophilic factor is manufactured with reduced amounts of von Willebrand Factor antigen (VWF:Ag) and purified from extraneous plasma-derived...
Approved
Matched Description: … G1, a long-lived plasma protein [A31551]. ... Antihemophilic factor human, also known as Coagulation Factor VIII or Anti-Hemophilic Factor (AHF), is ... half-life compared with conventional factor VIII due to conjugation to the dimeric Fc domain of human immunoglobulin …
Matched Mixtures name: … Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection ... Feiba Vh Immuno Anti Inhibitor ... Haemate P Powder and solvent for solution for injection or infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000 IU ... Beriate 1000 IU Powder and solvent for solution for injection or infusion ... NUWIQ POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …

Fibrinogen human

Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … It is a physiological substrate for three enzymes: plasmin, factor XIIIa and thrombin. ... acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and …
Matched Mixtures name: … ARTISS 10 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET ... TISSEEL 10 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR 1 ADET ... BERIPLAST-P COMBI SET 1 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … Fibryga 1g Powder and Solvent for Solution for Injection or Infusion ... FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... FIBRYGA 1 g Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung …

Polyethylene glycol

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … [A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water ... when molecular weights are <1000 and the molecule turns to waxy solids with increasing molecular weights ... [A190978] The most common preparations of PEGs include PEG 3350 and PEG 400. …
Matched Mixtures name: … LUBTANE %0,4 + %0,3 LUBRİKANT GÖZ DAMLASI, ÇÖZELTİ, 1 ADET, 10 ML ... PCP 100 Kit ... SYSTANE LUBRIKANT % 0,4 + %0,3 GÖZ DAMLASI, ÇÖZELTI, 15 ML …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … FORLAX POWDER FOR ORAL SOLUTION 10 g/sachet ... Forlax 10 g Pulver zur Herstellung einer Lösung zum Einnehmen ... CASENLAX 10 G ORAL ÇÖZELTİ HAZIRLAMAK İÇİN TOZ İÇEREN SAŞE , 20 ADET …

Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen

Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an allogeneic cellularized scaffold product used for the treatment of adults with thermal burns containing intact dermal elements for which surgical intervention is clinically indicated (also known as deep partial-thickness burns). It was developed as an alternative to autografting...
Approved
Matched Synonyms: … Viable and metabolically active allogeneic human NIKS keratinocytes and human dermal fibroblasts cellularized ... allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat …
Matched Name: … Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen …
Matched Description: … active and viable cells, provide a variety of human growth factors and cytokines as well as extracellular ... Stratagraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is an ... developed as an alternative to autografting - the process by which a patient's own skin is harvested and …

EDIT-301

EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2).
Investigational
Matched Synonyms: … Autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/CAS12a at the HBG1 and HBG2 ... ) at the HBG1 and HBG2 promoters ... autologous CD34+ hematopoietic stem and progenitor cells edited by CRISPR/Cas12a ribonucleoprotein (RNP …
Matched Description: … cells edited by CRISPR/CAS12a at the gamma globin gene (HBG1 and HBG2). ... EDIT-301 is an investigational cell therapy consisting of autologous CD34+ hematopoietic stem and progenitor …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Synonyms: … 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole ... 1-(o-Chlorotrityl)imidazole ... 1-(o-Chloro-α,α-diphenylbenzyl)imidazole …
Matched Iupac: … 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole …
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … Imazol duo 10 mg/g + 2,5 mg/g Creme ... MYKOFUNGIN 3 200MG+10MG/G ... MYKOFUNGIN 3 200MG+10MG/G …
Matched Categories: … Anti-Infective Agents ... Imidazole and Triazole Derivatives ... Anti-Infective Agents, Local ... Antiinfectives and Antiseptics for Local Oral Treatment ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Terrasil Foot and Nail Anti-Fungal ... Shield and Protect Anti-Fungal ... Terrasil Foot and Nail Anti-Fungal Maximum Strength …

Givastomig

Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody.
Investigational
Matched Synonyms: … an anti-Claudin 18.2 and 4.1BB Bispecific Antibody …
Matched Description: … Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody. …

Cabazitaxel

Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. ... -TRIYL 4-ACETATE 2-BENZOATE 13-((2R,3S)-3-(((TERT-BUTOXY)CARBONYL)AMINO)-2-HYDROXY-3-PHENYLPROPANOATE …
Matched Iupac: … (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy ... -3-phenylpropanoyl]oxy}-1-hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0 ... ^{3,10}.0^{4,7}]heptadec-13-en-2-yl benzoate …
Matched Description: … [A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17 ... Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree ... penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel]. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Cabazitaxel EVER Pharma 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... Cabazitaxel ratiopharm 10 mg/ml Konzentrat zur Herstellung einer Infusionslösung ... JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric ... has structural and functional characteristics similar to those of endogenous factor IX. ... has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and …
Matched Products: … BeneFIX, Powder and Solvent for solution for Injection 1000 IU/Vial. ... BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 250iu/vial …

TRK-001

TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Synonyms: … Rapamycin and Transforming Growth Factor-beta ... Natural Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), …

Benzalkonium

Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Description: … Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase ... This salt is used in a great variety of international pharmaceutical products such as eye, ear, and nasal ... When used as an ingredient in antiseptic and disinfectant products however, it is an active antimicrobial …
Matched Mixtures name: … 10 Person ANSI ... 10 Person ANSI ... FIRST AID Contains 101 PIECES …
Matched Categories: … Antiseptics and Disinfectants ... Anti-Infective Agents ... Anti-Infective Agents, Local ... Miscellaneous Local Anti-infectives …
Matched Products: … ZEFIREKS 10 G/100 ML, 1000 ML ... BENZAL %10 SOLUSYON, 100 ML ... Foam 103 …

Benzoyl peroxide

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover …
Matched Mixtures name: … OXIMIN 10 MG/G + 50 MG/G JEL,50 G ... OXIMIN 10 MG/G + 50 MG/G JEL,25 G ... Acne Vanishing Gel- 10% with Sulfur …
Matched Categories: … Anti-Acne Preparations ... Anti-Acne Preparations for Topical Use …
Matched Products: … Clean and Clear Persa-Gel 10 ... Clean and Clear persa-gel 10 Maximum Strength ... Benzagel 10 Gel 10% …

Lutikizumab

Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … Immunoglobulin, anti-(interleukin 1.beta./interleukin 1.alpha.) …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immunoglobulins …

Talquetamab

Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP ... IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP ... IMMUNOGLOBULIN G4 (233-PROLINE,239-ALANINE,240-ALANINE,410-LEUCINE,414-LYSINE), ANTI-(HUMAN CD3 ANTIGEN …
Matched Description: … It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... arm comprising a heavy and light chain. ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immunoglobulins …

Allantoin

Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, the plasma allantoin concentration rapidly increases about two fold and remains...
Approved
Matched Description: … , in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions [A32213]. ... Allantoin is a substance that is endogenous to the human body and also found as a normal component of ... During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated …
Matched Mixtures name: … NOSKAR 100 MG/50 IU/10 MG / G, JEL 100 G ... NOSKAR 100 MG/50 IU/10 MG / G, JEL 120 G ... NOSKAR 100 MG/50 IU/10 MG / G, JEL 50 G …
Matched Categories: … Basic Ointments and Protectants ... Herbs and Natural Products ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Miracle GYN (10 Tablets) ... Jilgyungyi (10 Tablets) ... Secret Gyno (10 Tablets) …

SP1049C

SP1049C is a novel anthracycline chemotherapeutic agent containing doxorubicin and two nonionic pluronic block copolymers. It is designed to overcome drug resistance in a number of cancers. It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. Preliminary data, in its first clinically tested indication,...
Investigational
Matched Synonyms: … doxorubicin with pluronics F-127 and L-61 ... Doxorubicin HCl with pluronic L-61 and pluronic F-127 …
Matched Description: … SP1049C is a novel anthracycline chemotherapeutic agent containing [doxorubicin] and two nonionic pluronic ... Median survival is encouraging and correlates strongly with dose levels.[A260416] ... It has successfully completed Phase 1 trials. Phase 2 results are currently under final review. …

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain ... alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NOVOEİGHT 1000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... NovoEight 500IU Powder and Solvent for Solution for Injection ... NOVOEIGHT®1000 UI POLVO Y SOLVENTE PARA SOLUCIÓN INYECTABLE …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … ADVATE 1000 IU Powder and Solvent for Solution for Injection ... ADVATE 1000 IU/5 ML IV ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... KOGENATE FS 1000 IU IV ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Products: … powder and solvent for solution for injection 1mg ... NOVOSEVEN RT 2 MG (100 KIU) ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ VE ÇÖZÜCÜ ... NOVOSEVEN 1MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Iupac: … 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol …
Matched Description: … Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate ... the pupil,[L9413] and induce local vasoconstriction. …
Matched Salts cas: … 1416-03-1 …
Matched Mixtures name: … MYDRIASERT 0,28 MG/5,4 MG GÖZ INSERTI ,10 INSERT ... DAYCOLD-HOT 500/10/15/100 MG SAŞE ,10 SAŞE ... DAYCOLD-HOT 500/10/15/100 MG SAŞE,6 SAŞE …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic and Dopaminergic Agents ... Adrenergic alpha-Agonists ... Mydriatics and Cycloplegics ... Decongestants and Antiallergics …
Matched Products: … FENOSED % 10 STERIL GÖZ DAMLASI, 5 ML ... FENİLEFRİN % 10 STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML ... Anti Hemorrhoidal H Suppository …

Camphor

Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Synonyms: … (1R,4R)-camphor ... (1R)-(+)-camphor …
Matched Iupac: … (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Description: … It is used topically as a skin antipruritic and as an anti-infective agent. ... contain a concentration higher than 11%. ... When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often …
Matched Mixtures name: … DIYENIL 100 ML LOSYON ... ANTIDOT 15 GR POMAD ... Holus Relief Gel, 1.7 oz …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics ... Anti-Infective Agents ... Anti-Infective Agents, Local …
Matched Products: … Camphor Spirit Liq 10% ... Band-aid Brand Anti-itch Gel ... Muscle and Joint HRX Pain Relieving …

Hydrocortisone acetate

Approved
Vet approved
Matched Iupac: … ,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H …
Matched Mixtures name: … UREACORT YAĞLI %0,5 + %10 KREM (30 G) ... KORTOS 27 MG/5 MG SUPOZİTUVAR, 10 ADET ... FUCIDIN H %2 + %1 KREM, 30 G …
Matched Categories: … Hydrocortisone and derivatives ... Anti-Inflammatory Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists ... 11-Hydroxycorticosteroids ... 17-Hydroxycorticosteroids …
Matched Products: … American Safety and First Aid ... Cortiment-10 Sup 10mg ... HİPOKORT FORTE %1 KREM, 30 G …

PlasmaCord

PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental blood. It is developed by Cellpraxis and is currently being investigated against severe acute respiratory syndrome (SARS).
Investigational
Matched Synonyms: … Human umbilical cord and placental blood plasma …
Matched Description: … PlasmaCord is platelet-poor plasma that is derived by fractionation from sterile umbilical cord and placental ... [L27581] It is developed by Cellpraxis and is currently being investigated against severe acute respiratory …
Displaying drugs 26 - 50 of 4223 in total