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Displaying drugs 26 - 50 of 366 in total

Antihemophilic factor (recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label]. Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation ... It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Moroctocog alfa

Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …

Pyrithione

Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat...
Approved
Matched Description: … and seborrheic dermatitis. ... of proteins essential for fungal metabolism and growth [A27132]. ... by fungi such as _Malassezia globosa_ and _M. restricta_ [A32162]. …
Matched Mixtures name: … Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Sachets Smooth and Silky …
Matched Products: … Head and Shoulders smooth and silky ... Head and Shoulders Smooth and Silky ... Head and Shoulders Full and Strong …

MM-111

MM-111 is a novel bispecific antibody fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and ERBB3.
Investigational
Matched Synonyms: … Antibody bispecific for erbb2 and erbb3 …
Matched Description: … fusion protein that co-targets the the epidermal growth factor family receptor tyrosine kinases, ERBB2 and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

CLL1-CD33 compound chimeric antigen receptor T cells

Investigational
Matched Synonyms: … Chimeric Antigen Receptor immunotherapy directed against CLL-1 and CD33 …

Lonoctocog alfa

Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... AFSTYLA 250IU powder and solvent for solution for injection …

Degarelix

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …

Smallpox and Monkeypox Vaccine, Live, Non-replicating

Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …

Aluminum zirconium octachlorohydrex gly

Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent , . It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. The anhydrous form of the compound also has water-absorbing properties. Currently, the FDA allows...
Approved
Matched Description: … It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. ... Aluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and …
Matched Mixtures name: … Lactovit DEODORANT AND ANTIPERSPIRANT INVISIBLE ANTISTAIN …
Matched Products: … Suave IS Sweet Pea and Violet Antiperspirant and Deodorant ... Degree Orange Flower and Cranberry Antiperspirant and Deodorant ... Degree Honeysuckle and Tea Tree Oil Antiperspirant and Deodorant …

Pasireotide

Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Somatostatin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... Signifor LAR 20mg powder and solvent for suspension for injection ... Signifor LAR 40mg powder and solvent for suspension for injection …

Albutrepenonacog alfa

Albutrepenonacog alfa (rIX-RFP) is a recombinant fusion protein that links a recombinant coagulation factor IX (rFIX) with a recombinant human albumin (rAlbumin). It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. It...
Approved
Matched Description: … It was also approved by FDA and EMA in 2016. ... It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305] ... [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Products: … IDELVION 250 IU powder and solvent for solution for injection ... IDELVION 500 IU powder and solvent for solution for injection ... IDELVION 1000 IU powder and solvent for solution for injection …

Turmeric oil

Approved
Experimental
Matched Synonyms: … Turmeric volatile oil ... Curcuma longa (turmeric) root oil …
Matched Name: … Turmeric oil …

Garlic oil

Experimental
Matched Name: … Garlic oil …
Matched Mixtures name: … Hovid Omega-3 + Garlic …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …

Rurioctocog alfa pegol

Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …

Romilkimab

Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Investigational
Matched Synonyms: … Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13) …
Matched Description: … Romilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in …

Menthol

Approved
Matched Mixtures name: … Turmeric Pain Relieving Cream ... Turmeric Pain Relieving Cream ... Turmeric Infused Hemp Pain Cream …
Matched Products: … Muscle and Joint ... Throat and Chest Chili and Lime ... Up and Up Hot and Cold Medicated …

Petrolatum

A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … It is used as an ointment base, topical protectant, and lubricant. …
Matched Mixtures name: … A and D Diaper Rash and Skin Protectant ... Vitamin A and D ... Vitamin A and D …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Procurevitamin A and D Vitamin A and D ... ProcureVITAMIN A AND D VITAMIN A AND D ... A and D …

Coagulation factor VIIa Recombinant Human

Recombinant human coagulation Factor VIIa (rFVIIa), intended for promoting hemostasis by activating the extrinsic pathway of the coagulation cascade. NovoSeven is a vitamin K-dependent glycoprotein consisting of 406 amino acid residues. Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form.
Approved
Matched Description: … Cloned and expressed in hamster kidney cells, the protein is catalytically active in a two-chain form …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … powder and solvent for solution for injection 2mg ... powder and solvent for solution for injection 1mg ... NOVOSEVEN 2MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Coagulation Factor IX (Recombinant)

Recombinant Coagulation Factor IX is a purified Factor IX glycoprotein produced by recombinant DNA technology. It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. It is not...
Approved
Investigational
Matched Description: … Recombinant Factor IX is indicated for the control and prevention of bleeding episodes in adult and pediatric ... has structural and functional characteristics similar to those of endogenous factor IX. ... has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and …
Matched Products: … BeneFIX , powder and solvent for solution for injection, 250 IU/Vial. ... BeneFIX Powder and Solvent for Solution for Injection 250iu/vial ... BeneFIX Powder and Solvent for Solution for Injection 1000iu/vial …

Reteplase

Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …

Menotropins

Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the urine of postmenopausal women. It is used as a fertility medication that is injected either subcutaneously or intramuscularly. It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with...
Approved
Matched Description: … Menotropins contains follicle stimulating hormone (FSH) and luteinizing hormone (LH) purified from the ... It is composed of LH with 2 subunits, alpha = 92 residues, beta = 121 residues and FSH with 2 subunits …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Menopur Powder for Injection and Solvent 75 IU ... MENOPUR multidose 600IU Powder and Solvent for Solution for Injection ... Menopur Powder and Solvent For Solution for Injection 75iu …

Selenium Sulfide

Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Description: … is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and …
Matched Mixtures name: … Clease and Treat …
Matched Products: … Head and Shoulders Itch ... Walgreens Dandruff and Conditioner Cleansing and Conditioning Anti-dandruff ... Head and Shoulders Clinical Strength …

Goflikicept

Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and …
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …

Antihemophilic factor, human recombinant

Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … ADVATE 250IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 500IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADVATE 1000IU, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Displaying drugs 26 - 50 of 366 in total