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Displaying drugs 1176 - 1200 of 1280 in total
Tick-borne encephalitis (TBE) is a disease caused by the TBE virus (TBEV), transmitted by ticks from the genus Ixodes. The disease course is variable. Some patients will be asymptomatic or experience a mild febrile illness, while others will experience the full course including neurological symptoms. TBE often manifests in a...
Approved
Matched Name: … Tick-borne encephalitis vaccine (whole virus, inactivated) …
Matched Description: … biphasic manner, with patients experiencing a flu-like illness followed by a variable asymptomatic period and ... neurological symptoms falling under the categorizations of meningitis, diffuse/focal meningoencephalitis, and ... While some patients recover fully following neurological TBE, neurological sequelae can last for years and
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Matched Synonyms: … 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate
Matched Iupac: … 6-oxo-6H,7H,8H,9H,10H,11H-cyclohepta[c]chromen-3-yl sulfamate
Matched Description: … Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast …
Matched Categories: … Steryl-Sulfatase, antagonists & inhibitors …
Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1,8-dihydroxyanthra-9,10-quinone
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity. …
Matched Categories: … Alimentary Tract and Metabolism ... Quinones
Experimental
Matched Synonyms: … C24:1 Sulfatide
Matched Name: … cis-tetracosenoyl sulfatide
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Synonyms: … N-acetylgalactosamine-4-sulfatase, recombinant human …
Matched Description: … The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and ... is conserved in all members of the sulfatase enzyme family. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Chondroitinases and Chondroitin Lyases ... Enzymes and Coenzymes …
Zolpidem, also known as Ambien, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. It is aimed for use in patients with difficulties initiating sleep. This drug decreases the time to fall asleep (sleep latency), increases the...
Approved
Matched Description: … This drug decreases the time to fall asleep (sleep latency), increases the duration of sleep, and decreases ... It is available in both immediate acting and extended release forms [FDA label], [F3802]. ... according to the manufacturer’s instructions, with a low risk of drug withdrawal, drug dependence, and
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Ambien ... Ambien CR …
One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Approved
Investigational
Vet approved
Matched Synonyms: … Chloridyn ... Chloridine
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... artesunate, sulfadoxine and pyrimethamine ... artesunate, sulfalene and pyrimethamine …
Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Approved
Matched Synonyms: … Sulfa-5-methoxypyrimidine …
Matched Description: … Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Sulfonamides and trimethoprim …
Fusarium graminearum allergenic extract is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … Gibberella zeae whole
Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Experimental
Matched Name: … Nicotinamide adenine dinucleotide phosphate …
Matched Description: … It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced ... Nicotinamide adenine dinucleotide phosphate. ... ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides ... Adenine Nucleotides …
A MET receptor tyrosine kinase inhibitor.
Investigational
Matched Synonyms: … 6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline
Matched Iupac: … 6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline
AGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.
Investigational
Matched Synonyms: … Recombinant human insulin receptor monoclonal antibody-fused iduronate 2-sulfatase
Matched Description: … (IDS) enzyme and a human insulin receptor monoclonal antibody. ... AGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase
Experimental
Matched Name: … P1-(adenosine-5'-P5-(uridine-5')pentaphosphate …
Experimental
Matched Name: … 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate …
Experimental
Matched Synonyms: … 2,3-Dimercapto-1-propane sulfonate
Investigational
Matched Synonyms: … 2-[4-(1-Methyl-4-pyridin-4-yl-lH-pyrazol-3-yl)-phenoxymethyl]-quinoline succinic acid …
Matched Iupac: … 2-({4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline
Experimental
Matched Name: … 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE …
Experimental
Matched Synonyms: … Allium Sativum bulb oil …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Hydrogen Sulfide
Investigational
Matched Synonyms: … P450 isoform 2B1 gene transfected human embryonic kidney 293 cells encapsulated in polymeric cellulose sulphate
Investigational
Matched Synonyms: … Hexadecanoic acid, 5,6,6a,7-tetrahydro-6-methyl-4h-dibenzo(de,g)quinoline-10,11-diyl ester, (r)- …
Experimental
Matched Name: … Carba-nicotinamide-adenine-dinucleotide …
Experimental
Matched Name: … Nicotinamide adenine dinucleotide cyclohexanone …
A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Experimental
Matched Name: … 3-Acetylpyridine Adenine Dinucleotide …
Matched Description: … electron carrier by being alternately oxidized (NAD+) and reduced (NADH). ... It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an ... A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides ... Adenine Nucleotides …
NSC-663284 is a potent quinolinedione Cdc25 phosphatase inhibitor.
Investigational
Matched Synonyms: … 6-chloro-7-((2-morpholinoethyl)amino)quinoline-5,8-dione …
Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Synonyms: … trastuzumab-anns
Matched Description: … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and ... KANJINTI (trastuzumab-anns) is another biosimilar approved by the FDA in June 2019. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... pertuzumab and trastuzumab ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Displaying drugs 1176 - 1200 of 1280 in total