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Displaying drugs 126 - 150 of 705 in total
Tofersen
Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2 ... (2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R ... Antisense Oligonucleotide Inhibitor Of The Expression Of Superoxide Dismutase 1 Gene …
Matched Description: … [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more ... [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … [L46133] Tofersen demonstrated efficacy in reducing the concentration of SOD1 in CSF and of neurofilament ... [A259023] However, it could potentially be due to the short timeframe of tofersen treatment, and more ... [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
3'-O-Acetylthymidine-5'-diphosphate
Experimental
Matched Synonyms: … 3'-O-Acetylthymidine 5'-(trihydrogen diphosphate) …
Matched Name: … 3'-O-Acetylthymidine-5'-diphosphate …
Matched Iupac: … acetyloxy)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Matched Name: … 3'-O-Acetylthymidine-5'-diphosphate …
Matched Iupac: … acetyloxy)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy …
Cyproterone acetate
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Synonyms: … Cyproterone 17-O-acetate …
Matched Description: … in combination with estrogen, for the therapy of severe acne and hirsutism in females. ... It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, ... An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties …
Matched Mixtures name: … OC - 35 …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... Antiandrogens and Estrogens ... cyproterone and estrogen ... Genito Urinary System and Sex Hormones ... Combination Contraceptives (with Estrogen and derivatives) …
Matched Products: … Andro - Diane 10 mg - Tabletten …
Matched Description: … in combination with estrogen, for the therapy of severe acne and hirsutism in females. ... It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, ... An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties …
Matched Mixtures name: … OC - 35 …
Matched Categories: … Sex Hormones and Modulators of the Genital System ... Antiandrogens and Estrogens ... cyproterone and estrogen ... Genito Urinary System and Sex Hormones ... Combination Contraceptives (with Estrogen and derivatives) …
Matched Products: … Andro - Diane 10 mg - Tabletten …
Nicotinamide
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Description: … Its primary significance is in the prevention and/or cure of blacktongue and pellagra. ... An important compound functioning as a component of the coenzyme NAD. ... Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and …
Matched Mixtures name: … Swiss One Multivitamin and Mineral Caplet ... One Daily Vitamin and Mineral Dietary Supplement ... Classic Swiss One 10 Multivitamin and Mineral Tab …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … O Hui White Extreme Cellshine Essence ... BK Cell 5DAYS OF SECRET SNOW WHITENING ... Gem Miracle Black Pearl O2 Whitening …
Matched Mixtures name: … Swiss One Multivitamin and Mineral Caplet ... One Daily Vitamin and Mineral Dietary Supplement ... Classic Swiss One 10 Multivitamin and Mineral Tab …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … O Hui White Extreme Cellshine Essence ... BK Cell 5DAYS OF SECRET SNOW WHITENING ... Gem Miracle Black Pearl O2 Whitening …
beta-D-Ribose-5-phosphate
Experimental
Matched Synonyms: … 5-O-phosphono-β-D-ribofuranose ... 5-O-phosphono-beta-D-ribofuranose …
Flubentylosin
Investigational
Matched Synonyms: … 4b-o-((4-fluorophenyl)methyl)tylosin ... Tylosin, 4b-o-((4-fluorophenyl)methyl)- …
Matched Iupac: … 6R)-4-(dimethylamino)-5-{[(2S,4R,5S,6S)-5-[(4-fluorophenyl)methoxy]-4-hydroxy-4,6-dimethyloxan-2-yl]oxy ... }-3-hydroxy-6-methyloxan-2-yl]oxy}-16-ethyl-4-hydroxy-15-({[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy- ... 6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde …
Matched Iupac: … 6R)-4-(dimethylamino)-5-{[(2S,4R,5S,6S)-5-[(4-fluorophenyl)methoxy]-4-hydroxy-4,6-dimethyloxan-2-yl]oxy ... }-3-hydroxy-6-methyloxan-2-yl]oxy}-16-ethyl-4-hydroxy-15-({[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy- ... 6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde …
PMC-403
PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Investigational
Matched Synonyms: … a fully human monoclonal antibody that binds and activates the Tie2 receptor …
Matched Description: … PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary …
Matched Description: … PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary …
TSHA-101
Investigational
Matched Synonyms: … adeno-associated viral vector serotype 9 (AAV9) carrying both HEXA and HEXB …
Daptomycin
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … 6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa …
Matched Description: … [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name ... bacteria, including methicillin-susceptible and -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant ... Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … CUBICIN® 350 MG POLVO PARA SOLUCIÓN INYECTABLE O INFUSIÓN ... CUBICIN® 500 MG POLVO PARA SOLUCION INYECTABLE O INFUSION ... DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL …
Matched Description: … [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name ... bacteria, including methicillin-susceptible and -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant ... Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … CUBICIN® 350 MG POLVO PARA SOLUCIÓN INYECTABLE O INFUSIÓN ... CUBICIN® 500 MG POLVO PARA SOLUCION INYECTABLE O INFUSION ... DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL …
FET F-18
FET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of Recurrent GBM to Avastin).
Investigational
Matched Synonyms: … O-18F-fluoroethyl-L-tyrosine ... O-(2-FLUOROETHYL)-L-TYROSINE F-18 …
Matched Description: … FET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of …
Matched Description: … FET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of …
Penicillium glaucum
Penicillium glaucum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, penicillium glaucum ... Molds, rusts and smuts, penicillium glaucus …
Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe)
Experimental
Matched Name: … Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe) …
Von Willebrand factor human
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF...
Approved
Investigational
Matched Description: … It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood ... [L1878] A recombinant form of vWF, [vonicog alfa], is also available to enhance production and avoid ... and hemophilia A. …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Matched Mixtures name: … Haemate P Powder and solvent for solution for injection or infusion ... Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for Injection ... Wilate 1000, 1000 IU VWF/1000 IU FVIII, Powder and Solvent for Solution for Injection …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... von Willebrand factor and coagulation factor VIII in combination …
Matched Products: … IMMUNATE 50 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... IMMUNATE 100 IU/ML POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
O-acetyl-L-serine
Experimental
Matched Synonyms: … O3-acetyl-L-serine …
Matched Name: … O-acetyl-L-serine …
Matched Name: … O-acetyl-L-serine …
Cyclouridine
Experimental
Matched Synonyms: … 2,2'-O-Cyclouridine …
Matched Iupac: … 4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.0^{2,6}]dodeca-8,11-dien-10-one …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.0^{2,6}]dodeca-8,11-dien-10-one …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Estradiol sulfamate
Investigational
Matched Synonyms: … Estradiol-3-O-Sulfamate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Hydroquinone
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Description: … As a result of these concerns, hydroquinone has been banned in the EU and UK. ... Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration ... sunspots, and freckles. …
Matched Mixtures name: … REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots ... REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots ... REVERS Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots Travel Size …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Hqra-otc ... CONDITION AND ENHANCE CLEAR Skin Bleaching and Corrector ... CONDITION AND ENHANCE BLENDER Skin Lightener and Blending …
Matched Mixtures name: … REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots ... REVERSE Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots ... REVERS Lightening Regimen for the Appearance of Stubborn Dark Marks, Patches and Age Spots Travel Size …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Hqra-otc ... CONDITION AND ENHANCE CLEAR Skin Bleaching and Corrector ... CONDITION AND ENHANCE BLENDER Skin Lightener and Blending …
Ethylmorphine
A narcotic analgesic and antitussive. It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function. It is not marketed in the US but is approved for use in various countries around the world. In the US it is a schedule II drug (single-entity) and...
Experimental
Illicit
Matched Synonyms: … 3-O-Ethylmorphine …
Matched Iupac: … -7(18),8,10,15-tetraen-14-ol ... (1S,5R,13R,14S,17R)-10-ethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... A narcotic analgesic and antitussive. ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... Heterocyclic Compounds with 4 or More Rings ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Iupac: … -7(18),8,10,15-tetraen-14-ol ... (1S,5R,13R,14S,17R)-10-ethoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … It is metabolized in the liver by ethylmorphine-N-demethylase and used as an indicator of liver function ... A narcotic analgesic and antitussive. ... In the US it is a schedule II drug (single-entity) and schedule III drug (in combination products). …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... Heterocyclic Compounds with 4 or More Rings ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide
Experimental
Matched Synonyms: … D-pyridoxyl-N,O-cycloserylamide-5-monophosphate …
Matched Name: … D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide …
Matched Iupac: … {[5-hydroxy-6-methyl-4-({[(4R)-3-oxo-1,2-oxazolidin-4-yl]amino}methyl)pyridin-3-yl]methoxy}phosphonic …
Matched Name: … D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide …
Matched Iupac: … {[5-hydroxy-6-methyl-4-({[(4R)-3-oxo-1,2-oxazolidin-4-yl]amino}methyl)pyridin-3-yl]methoxy}phosphonic …
5'-O-(L-Cysteinylsulfamoyl)adenosine
Experimental
Matched Synonyms: … 5'-O-(N-(L-Cysteinyl)-sulfamoyl)adenosine …
Matched Name: … 5'-O-(L-Cysteinylsulfamoyl)adenosine …
Matched Iupac: … 4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-sulfanylpropan-1-one …
Matched Name: … 5'-O-(L-Cysteinylsulfamoyl)adenosine …
Matched Iupac: … 4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}sulfonyl)amino]-3-sulfanylpropan-1-one …
Allolactose
Experimental
Matched Synonyms: … 6-O-β-D-galactopyranosyl-D-glucopyranose …
Matched Iupac: … (3R,4S,5S,6R)-6-({[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5 …
Matched Iupac: … (3R,4S,5S,6R)-6-({[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxane-2,3,4,5 …
trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-)
Experimental
Matched Synonyms: … N-methyl O-nitrophenyl aminoethyldiphosphate beryllium trifluoride …
Matched Name: … trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium …
Matched Iupac: … ({hydroxy[(trifluoroberylliuide)oxy]phosphoryl}oxy)({2-[methyl(2-nitrophenyl)amino]ethoxy})phosphinic …
Matched Name: … trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium …
Matched Iupac: … ({hydroxy[(trifluoroberylliuide)oxy]phosphoryl}oxy)({2-[methyl(2-nitrophenyl)amino]ethoxy})phosphinic …
KRN-7000
KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With Hematological Malignancies Undergoing AHSCT.
Investigational
Matched Synonyms: … 1-O-(α-D-galactopyranosyl)-N-hexacosanoylphytosphingosine …
Matched Iupac: … N-[(2S,3S,4R)-3,4-dihydroxy-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}octadecan …
Matched Description: … B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With ... KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis …
Matched Iupac: … N-[(2S,3S,4R)-3,4-dihydroxy-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}octadecan …
Matched Description: … B, Chronic, Unspecified Adult Solid Tumor, Protocol Specific, and Prevention of GvHD in Patients With ... KRN7000 has been used in trials studying the treatment of Lung Cancer, Chronic Hepatitis C, Hepatitis …
Displaying drugs 126 - 150 of 705 in total