Displaying drugs 26 - 41 of 41 in total
Edoxaban
Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved
Matched Description: … INR testing, and numerous drug-drug and drug-food interactions. ... atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism ... Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting …
Matched Categories: … Blood and Blood Forming Organs …
Matched Categories: … Blood and Blood Forming Organs …
Andexanet alfa
Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018. It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of anticoagulation in combination with rivaroxaban and apixaban...
Approved
Investigational
Matched Description: … deters the andexanet alfa from converting prothrombin to thrombin [A35558]. ... Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. ... Andexanet alfa retains the structural similarity to that of endogenous human factor Xa, but exists in …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
alpha-Tocopherol succinate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Description: … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet ... d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and ... esters using acetic or succinic acid, making a compound such as alpha-tocopherol succinate more stable and …
Matched Mixtures name: … Co-q10 and Vitamin E ... Multi-Vitamin Fluoride and Iron Drops ... Revit Multi-vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition …
Matched Mixtures name: … Co-q10 and Vitamin E ... Multi-Vitamin Fluoride and Iron Drops ... Revit Multi-vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition …
alpha-Tocopherol acetate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Matched Description: … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet ... d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and ... At the moment however, there exists a lack of formal data and evidence to support any such additional …
Matched Mixtures name: … Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals ... Essential Vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition …
Matched Mixtures name: … Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals ... Essential Vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition …
Alpha-1-proteinase inhibitor
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … .Alpha.1-proteinase inhibitor human ... Alfa 1-proteinase inhibitor (human) ... Alpha 1-proteinase inhibitor human …
Matched Description: … fractionation followed by PEG and zinc chloride fractionation. ... Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol …
Matched Categories: … Human alpha-1 Proteinase Inhibitor ... Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Alpha1-proteinase Inhibitor (human) …
Matched Description: … fractionation followed by PEG and zinc chloride fractionation. ... Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol …
Matched Categories: … Human alpha-1 Proteinase Inhibitor ... Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Alpha1-proteinase Inhibitor (human) …
Protein C
Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Synonyms: … Human protein C ... Protein C human ... Protein C concentrate human …
Matched Description: … VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation. ... A lack of protein C in the body would lead to unchecked coagulation activation, resulting in thrombin ... It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to Activated Protein …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Description: … VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation. ... A lack of protein C in the body would lead to unchecked coagulation activation, resulting in thrombin ... It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface to Activated Protein …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Thrombomodulin Alfa
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin (human 498-amino acid fragment) …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Receptors, Thrombin ... Amino Acids, Peptides, and Proteins …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Receptors, Thrombin ... Amino Acids, Peptides, and Proteins …
Catridecacog
Coagulation Factor XIII A-Subunit (Recombinant), also known as catridecacog, is a recombinant form of the Factor XIII-A2 homodimer composed of two factor XIII (FXIII) A-subunits [FDA Label]. For people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential...
Approved
Matched Synonyms: … Blood Coagulation Factor XIII (Synthetic Human A-Chain Precursor) ... Human Factor XIII (A2) homodimer (allele F13A*1B), recombinant DNA origin …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... When activated by thrombin at the site of injury, the FXIII A2B2 pro-enzyme is cleaved resulting in activation ... ) include [DB12909], which is a purified endogenous (human) form of coagulation factor XIII. …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … then isolated, the human form is isolated from pooled human plasma. ... When activated by thrombin at the site of injury, the FXIII A2B2 pro-enzyme is cleaved resulting in activation ... ) include [DB12909], which is a purified endogenous (human) form of coagulation factor XIII. …
Matched Categories: … Blood and Blood Forming Organs …
Turoctocog alfa
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any human- or animal-derived ... [A31504] It was developped by Novo Nordisk and FDA approved in October 16, 2013.[L1104] ... rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NovoEight 500IU Powder and Solvent for Solution for Injection ... NovoEight 1000IU Powder and Solvent for Solution for Injection ... NovoEight® 250IU Powder and Solvent for Solution for Injection …
Rurioctocog alfa pegol
Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor. Factor VIII is an essential protein involved in normal blood clotting; thus, a deficient level of functional factor VIII is associated with an elevated risk for excessive bleeding caused by spontaneous or secondary events like trauma...
Approved
Experimental
Matched Description: … Rurioctocog alfa pegol is a pegylated recombinant human coagulation factor VIII or antihemophilic factor ... Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and ... alfa pegol aims to restore functional levels of factor VIII in patients with hemophilia A to manage and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 1500IU Powder and Solvent for Solution for Injection ... ADYNOVATE 2000IU Powder and Solvent for Solution for Injection ... ADYNOVATE 1000IU Powder and Solvent for Solution for Injection …
Vorapaxar
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Description: … By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related …
Matched Categories: … Blood and Blood Forming Organs ... Receptors, Thrombin, antagonists & inhibitors …
Matched Categories: … Blood and Blood Forming Organs ... Receptors, Thrombin, antagonists & inhibitors …
Desirudin
Desirudin is a direct inhibitor of human thrombin. It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. Hirudin is a single polypeptide chain of 65 amino acids residues and contains three disulfide...
Approved
Matched Description: … Desirudin is a direct inhibitor of human thrombin. ... Hirudin is a single polypeptide chain of 65 amino acids residues and contains three disulfide bridges ... include: Bleeding gums, collection of blood under the skin, coughing up blood, deep, dark purple bruise and …
Matched Categories: … Thrombin Inhibitors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Thrombin Inhibitors ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Phenprocoumon
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs …
Nafamostat
Nafamostat is a synthetic serine protease inhibitor that is commonly formulated with hydrochloric acid due to its basic properties. It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome. The use of nafamostat in Asian countries is approved as an anticoagulant therapy for patients undergoing...
Investigational
Matched Description: … It has been used in trials studying the prevention of Liver Transplantation and Postreperfusion Syndrome …
TP-508
TP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified as the fibroblast high-affinity receptor binding domain.
Investigational
Matched Description: … TP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified …
SR-123781A
SR-123781A is a synthetic hexadecasaccharide Factor IIa and Xa antagonist. It is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary syndromes (ACS).
Investigational
Matched Description: … It is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary ... SR-123781A is a synthetic hexadecasaccharide Factor IIa and Xa antagonist. …
Matched Categories: … Heparin and similars …
Matched Categories: … Heparin and similars …
Displaying drugs 26 - 41 of 41 in total