Prothrombin

Details

Name
Prothrombin
Kind
protein
Organism
Human
Polypeptides
NameUniProt ID
ProthrombinP00734Details

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB00001LepirudinapprovedyesinhibitorDetails
DB00006Bivalirudinapproved, investigationalyesinhibitorDetails
DB00278Argatrobanapproved, investigationalyesinhibitorDetails
DB00170Menadioneapproved, nutraceuticalunknownactivatorDetails
DB01123Proflavineapprovednoother/unknownDetails
DB027234-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl)-Piperidin-4-Ylmethyl]-AmideexperimentalunknownDetails
DB03847Gamma-Carboxy-Glutamic AcidexperimentalunknownDetails
DB04136LysophosphotidylserineexperimentalunknownDetails
DB00055Drotrecogin alfaapproved, investigational, withdrawnunknownDetails
DB00100Coagulation Factor IX (Recombinant)approvedunknownDetails
DB04898Ximelagatranapproved, investigational, withdrawnyesinhibitorDetails
DB04591N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN-4-AMINEexperimentalunknownDetails
DB04697TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDEexperimentalunknownDetails
DB047222-(3-CHLORO-6-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-1-OXIDOPYRIDIN-2-YL)-N-[1-(3-CHLOROPHENYL)ETHYL]ACETAMIDEexperimentalunknownDetails
DB047711-GUANIDINO-4-(N-NITRO-BENZOYLAMINO-L-LEUCYL-L-PROLYLAMINO)BUTANEexperimentalunknownDetails
DB047721-GUANIDINO-4-(N-PHENYLMETHANESULFONYL-L-LEUCYL-L-PROLYLAMINO)BUTANEexperimentalunknownDetails
DB04786Suraminapproved, investigationalunknowninhibitorDetails
DB05777Thrombomodulin Alfaapproved, investigationalyesinhibitorDetails
DB06695Dabigatran etexilateapprovedyesinhibitorDetails
DB06838methyl L-phenylalaninateexperimentalunknownDetails
DB06841D-phenylalanyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl)butyl]-L-prolinamideexperimentalunknownDetails
DB06845(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB06850(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB06853N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB017252-{2-hydroxy-[1,1'-biphenyl]-3-yl}-1H-1,3-benzodiazole-5-carboximidamideexperimentalunknownDetails
DB038656-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-CarboxamidineexperimentalunknownDetails
DB06858N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB06859N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDEexperimentalunknownDetails
DB068616-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINEexperimentalunknownDetails
DB068656-CARBAMIMIDOYL-2-[2-HYDROXY-6-(4-HYDROXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACIDexperimentalunknownDetails
DB068666-CARBAMIMIDOYL-2-[2-HYDROXY-5-(3-METHOXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACIDexperimentalunknownDetails
DB06868N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamideexperimentalunknownDetails
DB068691-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDEexperimentalunknownDetails
DB068781-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamideexperimentalunknownDetails
DB06911D-leucyl-N-(3-chlorobenzyl)-L-prolinamideexperimentalunknownDetails
DB06919D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamideexperimentalunknownDetails
DB069291-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB06936N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamideexperimentalunknownDetails
DB06942N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamideexperimentalunknownDetails
DB069471-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB06996D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamideexperimentalunknownDetails
DB07005D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamideexperimentalunknownDetails
DB07016(3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinolineexperimentalunknownDetails
DB07027D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamideexperimentalunknownDetails
DB07083beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamideexperimentalunknownDetails
DB07088(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB07091(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB07095(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB071052-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDEexperimentalunknownDetails
DB07120N4-(N,N-DIPHENYLCARBAMOYL)-AMINOGUANIDINEexperimentalunknownDetails
DB07128N7-BUTYL-N2-(5-CHLORO-2-METHYLPHENYL)-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2,7-DIAMINEexperimentalunknownDetails
DB07131(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamideexperimentalunknownDetails
DB07133D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamideexperimentalunknownDetails
DB07143D-phenylalanyl-N-benzyl-L-prolinamideexperimentalunknownDetails
DB07165N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDEexperimentalunknownDetails
DB071903-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamideexperimentalunknownDetails
DB03159CRA_8696experimentalunknownDetails
DB07211(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDEexperimentalunknownDetails
DB072772-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDEexperimentalunknownDetails
DB072782-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHENESULFONAMIDEexperimentalunknownDetails
DB07279N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDEexperimentalunknownDetails
DB073534-(2,5-DIAMINO-5-HYDROXY-PENTYL)-PHENOLexperimentalunknownDetails
DB073662-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTERexperimentalunknownDetails
DB073765-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)experimentalunknownDetails
DB074001-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINEexperimentalunknownDetails
DB01767Hemi-BabimexperimentalunknownDetails
DB074404-TERT-BUTYLBENZENESULFONIC ACIDexperimentalunknownDetails
DB074613-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONEexperimentalunknownDetails
DB022872-(2-Hydroxy-Phenyl)-3h-Benzoimidazole-5-CarboxamidineexperimentalunknownDetails
DB075084-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINEexperimentalunknownDetails
DB075151-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OLexperimentalunknownDetails
DB075216-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OLexperimentalunknownDetails
DB07522N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDEexperimentalunknownDetails
DB07527N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDEexperimentalunknownDetails
DB075482-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDEexperimentalunknownDetails
DB075492-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-3-METHYL-6-PYRIDINYL)METHYL]ACETAMIDEexperimentalunknownDetails
DB075502-(6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDO-2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUOROPHENYL)METHYL]ACETAMIDEexperimentalunknownDetails
DB076393-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTERexperimentalunknownDetails
DB07658AC-(D)PHE-PRO-BOROLYS-OHexperimentalunknownDetails
DB07659AC-(D)PHE-PRO-BOROHOMOLYS-OHexperimentalunknownDetails
DB07660AC-(D)PHE-PRO-BOROHOMOORNITHINE-OHexperimentalunknownDetails
DB07665N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamideexperimentalunknownDetails
DB077183-(4-HYDROXY-PHENYL)PYRUVIC ACIDexperimentalunknownDetails
DB031364-Iodobenzo[B]Thiophene-2-CarboxamidineexperimentalunknownDetails
DB077414-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINEexperimentalunknownDetails
DB07796(3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINEexperimentalunknownDetails
DB078094-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDEexperimentalunknownDetails
DB078971-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANEexperimentalunknownDetails
DB07934[[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINEexperimentalunknownDetails
DB07944N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDEexperimentalunknownDetails
DB07946N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamideexperimentalunknownDetails
DB080614-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINEexperimentalunknownDetails
DB080623-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLEexperimentalunknownDetails
DB08152{(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetateexperimentalunknownDetails
DB08187METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINEexperimentalunknownDetails
DB01766Beta-(2-Naphthyl)-AlanineexperimentalunknownDetails
DB082542-NAPHTHALENESULFONIC ACIDexperimentalunknownDetails
DB08422[PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINEexperimentalunknownDetails
DB085464-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDEexperimentalunknownDetails
DB08624BENZOTHIAZOLEexperimentalunknownDetails
DB00025Antihemophilic factor, human recombinantapproved, investigationalunknownactivatorDetails
DB06404Human C1-esterase inhibitorapprovedunknowninhibitorDetails
DB09228Conestat alfaapprovedyesinhibitorDetails
DB11166Antithrombin AlfaapprovedyesinhibitorDetails
DB12831GabexateinvestigationalyesinhibitorDetails
DB12598Nafamostatapproved, investigationalyesinhibitorDetails
DB13152Coagulation Factor IX HumanapprovedunknownDetails
DB13151Anti-inhibitor coagulant complexapprovedyesagonistDetails
DB13151Anti-inhibitor coagulant complexapprovedyessubstrateDetails
DB09130CopperapprovedunknownDetails
DB01593ZincapprovedunknownDetails
DB12364Betrixabanapproved, investigationalyesinhibitorDetails