Dihydrofolate reductase

Details

Name
Dihydrofolate reductase
Kind
protein
Organism
Human
Polypeptides
NameUniProt ID
Dihydrofolate reductaseP00374Details

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB00563MethotrexateapprovedyesinhibitorDetails
DB01157Trimetrexateapproved, investigationalyesinhibitorDetails
DB00157NADHnutraceuticalunknownDetails
DB00642Pemetrexedapproved, investigationalyesinhibitorDetails
DB00440Trimethoprimapproved, vet_approvednoinhibitorDetails
DB01131ProguanilapprovedyesinhibitorDetails
DB021042,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]PyrimidineexperimentalunknownDetails
DB025596-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-DiamineexperimentalunknownDetails
DB02583N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-TriamineexperimentalunknownDetails
DB029192,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]PyrimidineexperimentalunknownDetails
DB03060Sri-9662experimentalunknownDetails
DB03351Sri-9439experimentalunknownDetails
DB034612'-Monophosphoadenosine 5'-DiphosphoriboseexperimentalunknownDetails
DB03695PiritreximinvestigationalunknownDetails
DB00205Pyrimethamineapproved, vet_approvedyesinhibitorDetails
DB03886BiopterinexperimentalunknownDetails
DB071405-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamineexperimentalunknownDetails
DB071415-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamineexperimentalunknownDetails
DB071425-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamineexperimentalunknownDetails
DB071445-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamineexperimentalunknownDetails
DB024272,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]QuinazolineexperimentalunknownDetails
DB039872,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]PyrimidineexperimentalunknownDetails
DB082345-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamineexperimentalunknownDetails
DB08406[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINEexperimentalunknownDetails
DB08448(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-olexperimentalunknownDetails
DB08642(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamineexperimentalunknownDetails
DB031252,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-IumexperimentalunknownDetails
DB00563MethotrexateapprovedunknownsubstrateDetails
DB06813PralatrexateapprovedyesinhibitorDetails
DB08878Aminopterininvestigational, withdrawnunknowninhibitorDetails
DB00798Gentamicinapproved, vet_approvedunknownDetails