Hematinics

Name
Hematinics
Accession Number
DBCAT000087
Description

Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.

Drugs
DrugDrug Description
Darbepoetin alfaA recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia.
ErythropoietinA recombinant form of human erythropoietin used to increase differentiation of progenitor cells to red blood cells in the treatment of anemia.
Folic acidA nutrient used to treat megaloblastic anemia and is found in many supplements.
HydroxocobalaminA synthetic form of vitamin B12 used to treat vitamin B12 associated disorders and cyanide poisoning.
Iron DextranAn iron supplement used to treat iron deficiency in patients who cannot take oral iron.
FerumoxytolAn intravenous iron replacement product used to treat iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD), or in patients who are unable to tolerate or who have not responded adequately to oral iron supplementation.
Ferric sulfateA medication used as a coagulant and hemostatic agent.
Iron protein succinylateNot Annotated
Ferrous sulfate anhydrousAn iron supplement used to prevent or treat iron deficiency anemia.
PegfilgrastimA recombinant human granulocyte colony stimulating factor used to stimulate the production of neutrophils and prevent febrile neutropenia or infections after myelosuppressive chemotherapy.
RomiplostimA fusion protein thrombopoietin (TPO) peptide analog that increases platelet counts by binding to and activating the human TPO receptor. Used to treat thrombocytopenia associated with chronic immune thrombocytopenia (ITP).
EltrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
PlerixaforA selective chemokine receptor (CXCR4) antagonist used with filgrastim to mobilize hematopoietic stem cells to the peripheral blood for collection and autologous transplantation in patients with non-Hodgkin’s lymphoma (NHL) and multiple myeloma (MM).
Methoxy polyethylene glycol-epoetin betaA synthetic erythropoiesis stimulating agent (ESA) used to treat anemia associated with chronic kidney disease.
Ferrous gluconateA medication used to treat iron-deficiency anemia.
Iron isomaltoside 1000Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer, Esophageal Cancer, Chronic Kidney...
Ferrous succinateUsed in preventing and treating iron-deficiency anemia.
Ferric maltolA complexed iron supplement used to treat iron deficiency in adults.
Drugs & Drug Targets
DrugTargetType
Darbepoetin alfaErythropoietin receptortarget
ErythropoietinErythropoietin receptortarget
Folic acidFolate receptor gammatarget
Folic acidFolate receptor betatarget
Folic acidMethylenetetrahydrofolate reductaseenzyme
Folic acidMultidrug resistance-associated protein 4transporter
Folic acidSolute carrier family 22 member 6transporter
Folic acidCanalicular multispecific organic anion transporter 2transporter
Folic acidATP-binding cassette sub-family C member 11transporter
Folic acidATP-binding cassette sub-family G member 2transporter
Folic acidProton-coupled folate transportertransporter
Folic acidMitochondrial folate transporter/carriertransporter
Folic acidGamma-glutamyl hydrolaseenzyme
Folic acidFolate receptor alphatarget
Folic acidDihydrofolate reductaseenzyme
HydroxocobalaminMethylmalonic aciduria type A protein, mitochondrialtarget
HydroxocobalaminProtein amnionlesstarget
HydroxocobalaminTranscobalamin-1target
HydroxocobalaminMethylmalonyl-CoA mutase, mitochondrialtarget
HydroxocobalaminMethionine synthasetarget
HydroxocobalaminCubilintarget
HydroxocobalaminMethylmalonic aciduria and homocystinuria type C proteintarget
HydroxocobalaminTranscobalamin-2carrier
Iron DextranHemoglobin subunit betatarget
Iron DextranHemoglobin subunit alphatarget
Iron DextranFerritin heavy chaintarget
Iron DextranFerritin light chaintarget
Iron DextranSerotransferrincarrier
FerumoxytolSerotransferrintransporter
FerumoxytolFerritin light chaintransporter
FerumoxytolFerritin heavy chaintransporter
Ferrous sulfate anhydrousNatural resistance-associated macrophage protein 2transporter
Ferrous sulfate anhydrousCeruloplasminenzyme
Ferrous sulfate anhydrousHemoglobin subunit alphatarget
Ferrous sulfate anhydrousTransferrin receptortarget
Ferrous sulfate anhydrousSolute carrier family 40 member 1transporter
Ferrous sulfate anhydrousHepcidinenzyme
Ferrous sulfate anhydrousSerotransferrinenzyme
Ferrous sulfate anhydrousHephaestinenzyme
Ferrous sulfate anhydrousCytochrome b reductase 1enzyme
PegfilgrastimGranulocyte colony-stimulating factor receptortarget
PegfilgrastimNeutrophil elastaseenzyme
RomiplostimThrombopoietin receptortarget
EltrombopagThrombopoietin receptortarget
EltrombopagCytochrome P450 2C8enzyme
EltrombopagCytochrome P450 1A2enzyme
EltrombopagUDP-glucuronosyltransferase 1-1enzyme
EltrombopagUDP-glucuronosyltransferase 1-3enzyme
EltrombopagSolute carrier organic anion transporter family member 1B1transporter
EltrombopagATP-binding cassette sub-family G member 2transporter
EltrombopagUDP-glucuronosyltransferase 1-9enzyme
PlerixaforC-X-C chemokine receptor type 4target
Methoxy polyethylene glycol-epoetin betaErythropoietin receptortarget
Ferrous gluconateTransferrin receptor protein 1target
Ferrous gluconateEgl nine homolog 1target
Ferrous gluconateHistone deacetylase 8target
Ferrous gluconateAlpha-hemoglobin-stabilizing proteintarget
Ferrous gluconateHemoglobin subunit alphatarget
Ferrous gluconateFrataxin, mitochondrialtarget
Ferrous gluconateFerritin heavy chaintarget
Ferrous gluconateFlap endonuclease 1target
Ferrous gluconateEndonuclease 8-like 1target
Ferrous gluconateEndonuclease 8-like 2target
Ferrous gluconateDNA polymerase betatarget
Ferrous gluconateCeruloplasmintarget
Ferrous gluconateSerotransferrintarget
Ferrous succinateTransferrin receptor protein 1target
Ferrous succinateEgl nine homolog 1target
Ferrous succinateHistone deacetylase 8target
Ferrous succinateAlpha-hemoglobin-stabilizing proteintarget
Ferrous succinateHemoglobin subunit alphatarget
Ferrous succinateFrataxin, mitochondrialtarget
Ferrous succinateFerritin heavy chaintarget
Ferrous succinateFlap endonuclease 1target
Ferrous succinateEndonuclease 8-like 1target
Ferrous succinateEndonuclease 8-like 2target
Ferrous succinateDNA polymerase betatarget
Ferrous succinateCeruloplasmintarget
Ferrous succinateSerotransferrintarget
Ferric maltolUDP-glucuronosyltransferase 1-6enzyme
Ferric maltolIntegrin beta-3target
Ferric maltolNatural resistance-associated macrophage protein 2target
Ferric maltolNatural resistance-associated macrophage protein 2transporter
Ferric maltolIntegrin beta-3transporter