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Identification
NameErythropoietin
Accession NumberDB00016  (BTD00103, BIOD00103)
TypeBiotech
GroupsApproved
DescriptionErythropoietin (as Epoetin alfa) is a 165-amino acid erythropoiesis-stimulating glycoprotein manufactured by recombinant DNA technology. It has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced. The product contains the identical amino acid sequence of isolated natural erythropoietin.
Protein structureDb00016
Related Articles
Protein chemical formulaC815H1317N233O241S5
Protein average weight18396.1 Da
Sequences
>DB00016 sequence
APPRLICDSRVLERYLLEAKEAENITTGCAEHCSLNENITVPDTKVNFYAWKRMEVGQQA
VEVWQGLALLSEAVLRGQALLVNSSQPWEPLQLHVDKAVSGLRSLTTLLRALGAQKEAIS
PPDAASAAPLRTITADTFRKLFRVYSNFLRGKLKLYTGEACRTGDR
Download FASTA Format
Synonyms
E.P.O.
Epoetin alfa
Epoetin alfa rDNA
Epoetin alfa, recombinant
Epoetin beta
Epoetin beta rDNA
Epoetin epsilon
Epoetin gamma
Epoetin gamma rDNA
Epoetin kappa
Epoetin omega
Erythropoiesis stimulating factor
Erythropoietin (human, recombinant)
Erythropoietin (recombinant human)
ESF
SH-polypeptide-72
External Identifiers
  • BM 06.019
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
AbseamedInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution40000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution40000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution40000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution40000 IU/1mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution40000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
AbseamedInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousMedice Arzneimittel Pütter Gmb H & Co. Kg2007-08-28Not applicableEu
BinocritInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution10000 IU/1mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution10000 IU/1mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution40000 IU/1mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution40000 IU/1mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution40000 IU/1mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution40000 IU/1mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution20000 IU/0.5mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BinocritInjection, solution40000 IU/1mlIntravenous; SubcutaneousSandoz2007-08-28Not applicableEu
BiopoinInjection, solution4000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution3000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution3000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution4000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution3000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution2000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution4000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution2000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
BiopoinInjection, solution2000 IU/0.5mlIntravenous; SubcutaneousTeva2009-10-23Not applicableEu
Epoetin Alfa HexalInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution40000 IU/1mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution8000 IU/0.8mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution6000 IU/0.6mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution3000 IU/0.3mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution4000 IU/0.4mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution9000 IU/0.9mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution2000 IU/1.0mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution30000 IU/0.75mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
Epoetin Alfa HexalInjection, solution7000 IU/0.7mlIntravenous; SubcutaneousHexal Ag  2007-08-28Not applicableEu
EpogenSolution10000 [iU]/mLIntravenous; SubcutaneousAmgen1994-12-05Not applicableUs
EpogenSolution10000 [iU]/mLIntravenous; SubcutaneousAmgen1993-08-16Not applicableUs
EpogenSolution20000 [iU]/mLIntravenous; SubcutaneousAmgen1997-03-03Not applicableUs
EpogenSolution4000 [iU]/mLIntravenous; SubcutaneousAmgen1993-08-16Not applicableUs
EpogenSolution3000 [iU]/mLIntravenous; SubcutaneousAmgen1990-04-30Not applicableUs
EpogenSolution2000 [iU]/mLIntravenous; SubcutaneousAmgen1989-06-30Not applicableUs
EporatioInjection, solution3000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution4000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution3000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution2000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution5000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution4000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution2000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution2000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution4000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution20000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution1000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution3000 IU/0.5mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution10000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
EporatioInjection, solution30000 IU/1.0mlIntravenous; SubcutaneousRatiopharm Inc2009-10-29Not applicableEu
Eprex Sterile SolutionSolution20000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals2005-08-24Not applicableCanada
Eprex Sterile SolutionSolution30000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals2007-11-19Not applicableCanada
Eprex Sterile Solution 10000iu/1.0mlSolution10000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1997-09-19Not applicableCanada
Eprex Sterile Solution 10000iu/mlSolution10000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1990-12-312014-10-09Canada
Eprex Sterile Solution 1000iu/0.5mlSolution1000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1997-09-19Not applicableCanada
Eprex Sterile Solution 20000iu/mlSolution20000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1996-10-022010-04-29Canada
Eprex Sterile Solution 2000iu/0.5mlSolution2000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1997-09-19Not applicableCanada
Eprex Sterile Solution 2000iu/mlSolution2000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1992-12-312014-09-25Canada
Eprex Sterile Solution 3000iu/0.3mlSolution3000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1997-09-19Not applicableCanada
Eprex Sterile Solution 40000iu/mlSolution40000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1999-12-21Not applicableCanada
Eprex Sterile Solution 4000iu/0.4mlSolution4000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1997-09-19Not applicableCanada
Eprex Sterile Solution 4000iu/mlSolution4000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals1990-12-312014-10-09Canada
Eprex Sterile Solution 5000iu/0.5mlSolution5000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals2002-07-01Not applicableCanada
Eprex Sterile Solution 6000 Iu/0.6 MlSolution6000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals2001-02-20Not applicableCanada
Eprex Sterile Solution 8000 Iu/0.8 MlSolution8000 unitIntravenous; SubcutaneousJanssen Pharmaceuticals2001-02-20Not applicableCanada
ProcritInjection, solution10000 [iU]/mLIntravenous; SubcutaneousPhysicians Total Care, Inc.1994-08-11Not applicableUs
ProcritInjection, solution40000 [iU]/mLIntravenous; SubcutaneousJanssen, Lp1989-06-01Not applicableUs
ProcritInjection, solution4000 [iU]/mLIntravenous; SubcutaneousJanssen, Lp1989-06-01Not applicableUs
ProcritInjection, solution20000 [iU]/mLIntravenous; SubcutaneousPhysicians Total Care, Inc.2008-03-24Not applicableUs
ProcritInjection, solution10000 [iU]/mLIntravenous; SubcutaneousJanssen, Lp1989-06-01Not applicableUs
ProcritInjection, solution2000 [iU]/mLIntravenous; SubcutaneousJanssen, Lp1989-06-01Not applicableUs
ProcritInjection, solution40000 [iU]/mLIntravenous; SubcutaneousPhysicians Total Care, Inc.2007-08-13Not applicableUs
ProcritInjection, solution10000 [iU]/mLIntravenous; SubcutaneousJanssen, Lp1989-06-01Not applicableUs
ProcritInjection, solution3000 [iU]/mLIntravenous; SubcutaneousJanssen, Lp1989-06-01Not applicableUs
ProcritInjection, solution20000 [iU]/mLIntravenous; SubcutaneousJanssen, Lp1989-06-01Not applicableUs
Approved Generic Prescription ProductsNot Available
Approved Over the Counter ProductsNot Available
Unapproved/Other Products Not Available
International Brands
NameCompany
BinocritSandoz
EpoceptLupin pharma
EpofitIntas pharma
EpoginChugai
NanokineNanogen Pharmaceutical biotechnology, Vietnam)
Brand mixturesNot Available
SaltsNot Available
Categories
UNII64FS3BFH5W
CAS number11096-26-7
Pharmacology
IndicationFor treatment of anemia (from renal transplants or certain HIV treatment)
Structured Indications
Clinical Trials
PhaseStatusPurposeConditionsCount
1CompletedNot AvailableAnemias / Chronic Kidney Failure1
1CompletedBasic ScienceRenal Effects1
1CompletedTreatmentAnemias / Chronic Kidney Disease (CKD)1
1CompletedTreatmentCerebral Palsy (CP)1
1CompletedTreatmentChronic Kidney Disease (CKD) / Pulmonary Hypertension (PH) / Sickle Cells Disease1
1CompletedTreatmentChronic Renal Failure (CRF)1
1CompletedTreatmentEncephalopathy, Hypoxic-Ischemic1
1CompletedTreatmentInfection, Human Immunodeficiency Virus1
1Not Yet RecruitingTreatmentHealthy4
1Not Yet RecruitingTreatmentTransplantation, Kidney1
1, 2Active Not RecruitingBasic ScienceHealthy1
1, 2Active Not RecruitingPreventionAortic Arch Hypoplasia or Interruption / Congenital Heart Disease (CHD) / Hypoplastic Left Heart Syndrome (HLHS) / Transposition of the Great Arteries1
1, 2Active Not RecruitingTreatmentBirth Asphyxia / Encephalopathy, Hypoxic-Ischemic / Neonatal Encephalopathy1
1, 2RecruitingTreatmentAnemias / Cardiovascular Diseases1
2Active Not RecruitingTreatmentAnemias1
2Active Not RecruitingTreatmentMyelodysplastic Syndromes1
2Active Not RecruitingTreatmentNewborn Infants1
2CompletedPreventionMyocardial Ischemia1
2CompletedPreventionOptic Neuritis1
2CompletedSupportive CareAnemias / Leukemias / Lymphoma NOS / Lymphoproliferative Disorders / Multiple Myeloma and Plasma Cell Neoplasm / Precancerous Conditions / Unspecified Adult Solid Tumor, Protocol Specific1
2CompletedTreatmentAcquired Immunodeficiency Syndromes / Anemias4
2CompletedTreatmentAnemia in End Stage Renal Disease1
2CompletedTreatmentAnemias5
2CompletedTreatmentAnemias / Blood Transfusions / Orthopedic Procedures1
2CompletedTreatmentAnemias / Cancers1
2CompletedTreatmentAnemias / Cancers / Leukemia, Lymphocytic / Leukemia, Lymphocytic, Chronic / Neoplasms / Quality of Life1
2CompletedTreatmentAnemias / Cancer treatment / Cancers1
2CompletedTreatmentAnemias / Chronic Kidney Disease (CKD)1
2CompletedTreatmentAnemias / Chronic Kidney Disease (CKD) / Chronic Renal Failure (CRF)1
2CompletedTreatmentAnemias / Chronic Renal Insufficiency1
2CompletedTreatmentAnemias / Critical Illness1
2CompletedTreatmentAnemias / End Stage Renal Disease (ESRD)1
2CompletedTreatmentAnemias / Kidney Diseases1
2CompletedTreatmentAnemias / Neoplasms3
2CompletedTreatmentAnemias / Renal Failure, Chronic1
2CompletedTreatmentAnemias / Cancer treatment1
2CompletedTreatmentAneurysmal Subarachnoid Hemorrhage1
2CompletedTreatmentBeta-Thalassemia1
2CompletedTreatmentFriedreich's Ataxia2
2CompletedTreatmentMoods Disorders1
2CompletedTreatmentMyelodysplastic Syndrome1
2CompletedTreatmentMyelodysplastic Syndromes3
2CompletedTreatmentMyocardial Infarction (MI)1
2CompletedTreatmentPreterm Infants1
2Not Yet RecruitingTreatmentAcute Myocardial Infarction (AMI)1
2Not Yet RecruitingTreatmentAnemias / Congenital Heart Disease (CHD) / Cyanosis / Cyanotic Congenital Heart Disease1
2Not Yet RecruitingTreatmentAngiogenesis / Stroke, Ischemic1
2Not Yet RecruitingTreatmentCerebral Palsy (CP)1
2RecruitingPreventionNeonatal Anemia1
2RecruitingTreatmentAnemias / Chronic Renal Failure (CRF) / Dialysis therapy1
2RecruitingTreatmentHead and Neck Cancers1
2RecruitingTreatmentMultiple Sclerosis (Primary or Secondary Progressive Phase)1
2RecruitingTreatmentTrauma, Multiple1
2TerminatedPreventionBrain Injury / Erythropoietin / Infants, Premature / Intraventricular Hemorrhage / Neurodevelopmental Outcomes / Periventricular Leukomalacia / Randomized Clinical Trial1
2TerminatedTreatmentAgeing / Anemias / Hemoglobins2
2TerminatedTreatmentAging / Anemias1
2TerminatedTreatmentAnemias2
2TerminatedTreatmentAnemias / Cancers / Epoetin Alfa1
2TerminatedTreatmentAnemias / Cancers / Neoplasms1
2TerminatedTreatmentAnemias / HIV Disease1
2TerminatedTreatmentAnemias / Rheumatoid Arthritis (RA)1
2TerminatedTreatmentAnemias / Surgery, Arthroscopy1
2TerminatedTreatmentEnd Stage Renal Disease (ESRD)1
2TerminatedTreatmentLeukemias1
2TerminatedTreatmentMyelodysplastic Syndromes1
2TerminatedTreatmentStroke1
2WithdrawnPreventionCancers1
2WithdrawnPreventionTraumatic Brain Injury (TBI)1
2WithdrawnTreatmentAnemias1
2WithdrawnTreatmentAnemias / Myelodysplastic Syndromes1
2WithdrawnTreatmentAnemias / Rheumatoid Arthritis (RA)1
2WithdrawnTreatmentInfection, Human Immunodeficiency Virus / Neuropathy1
2WithdrawnTreatmentStroke1
2, 3CompletedTreatmentAnemias / Blood Transfusions / Orthopedic Procedures1
2, 3CompletedTreatmentBlood Transfusions / Blood Transfusions, Autologous / Cardiovascular Surgical Procedures / Mammaplasty / Orthopedic Procedures / Orthopedic Surgery1
2, 3CompletedTreatmentBlood Transfusions / Blood Transfusions, Autologous / Cardiovascular Surgical Procedures / Orthopedic Procedures / Orthopedic Surgery1
2, 3CompletedTreatmentInfant, Low Birth Weight / Infant, Small for Gestational Age / Infants, Premature / Neonatal Anemia / Newborn Infants1
2, 3RecruitingTreatmentMalaria, Cerebral1
2, 3RecruitingTreatmentPerinatal Asphyxia1
3Active Not RecruitingTreatmentCervix Cancer1
3CompletedDiagnosticAnemias1
3CompletedPreventionAnemias / Kidney Failure / Left Ventricular Hypertrophy1
3CompletedSupportive CareAcute Myelogenous Leukaemia (AML) / Leukemias / Myelodysplastic Syndrome1
3CompletedSupportive CareAnemias / Leukemias / Lymphoma NOS / Lymphoproliferative Disorders / Multiple Myeloma and Plasma Cell Neoplasm / Precancerous/Nonmalignant Condition / Unspecified Adult Solid Tumor, Protocol Specific1
3CompletedTreatmentAnemias14
3CompletedTreatmentAnemias / Blood Transfusions, Autologous / Orthopedic Procedures1
3CompletedTreatmentAnemias / Blood Transfusions / Orthopedic Procedures1
3CompletedTreatmentAnemias / Cancer, Breast / Cancer, Ovarian / Esophagus Cancer / Lymphoma NOS / Multiple Myeloma (MM) / Neoplasms / Prostate Cancers / Small Cell Lung Carcinoma1
3CompletedTreatmentAnemias / Cancers / Neoplasms1
3CompletedTreatmentAnemias / Cancer treatment / Cancers1
3CompletedTreatmentAnemias / Chronic Kidney Disease (CKD)1
3CompletedTreatmentAnemias / Chronic Kidney Disease (CKD) / Chronic Renal Failure (CRF)2
3CompletedTreatmentAnemias / Hodgkins Disease (HD) / Leukemias / Non-Hodgkin's Lymphoma (NHL)1
3CompletedTreatmentAnemias / Kidney Failure,Chronic1
3CompletedTreatmentAnemias / Multiple Myeloma (MM)1
3CompletedTreatmentAnemias / Neoplasms1
3CompletedTreatmentAnemias / Neoplasms, Breast / Quality of Life1
3CompletedTreatmentAnemias / Renal Diseases1
3CompletedTreatmentAnemias / Thrombosis, Venous1
3CompletedTreatmentAngioplasty, Transluminal, Percutaneous Coronary / Myocardial Infarction (MI)1
3CompletedTreatmentCarcinomas / Prostate1
3CompletedTreatmentChronic Hepatitis C (CHC)1
3CompletedTreatmentHepatitis C1
3CompletedTreatmentHepatitis C, Chronic1
3CompletedTreatmentHip Fractures1
3CompletedTreatmentKidney Failure1
3CompletedTreatmentPredialysis Patients1
3CompletedTreatmentRectal Neoplasms / Stomach Neoplasms1
3CompletedTreatmentTraumatic Brain Injury (TBI)1
3Not Yet RecruitingTreatmentAnemias / Chronic Kidney Disease (CKD)1
3RecruitingPreventionChronic Kidney Insufficiency / Diabetes1
3RecruitingTreatmentAnemia in Incident Dialysis Patients1
3RecruitingTreatmentAnemias2
3RecruitingTreatmentAnemias / Aortic Stenosis1
3RecruitingTreatmentAnemias / End Stage Renal Disease (ESRD)1
3RecruitingTreatmentBirth Asphyxia / Neonatal Encephalopathy1
3RecruitingTreatmentCKD Anemia in Stable Dialysis Patients1
3RecruitingTreatmentExtreme Prematurity1
3RecruitingTreatmentIntraventricular Hemorrhage of Prematurity1
3RecruitingTreatmentOptic Nerve Diseases1
3SuspendedTreatmentSpinal Cord Injuries (SCI)1
3TerminatedTreatmentAnemias5
3TerminatedTreatmentAnemias / Cancers1
3TerminatedTreatmentAnemias / Chemotherapy, Adjuvant / Hemoglobins / Neoplasms, Breast / Quality of Life1
3TerminatedTreatmentAnemias / Lung Cancers / Non-Small-Cell Lung Carcinoma (NSCLC)1
3TerminatedTreatmentAnemias / Myelodysplastic Syndromes1
3TerminatedTreatmentAnemias / Neoplasms1
3TerminatedTreatmentDrug Resistance / Kidney Failure,Chronic1
3TerminatedTreatmentGastrointestinal Cancers / Rectal Cancers1
3WithdrawnTreatmentAnemias / Blood Transfusions / Orthopedic Surgery1
4Active Not RecruitingPreventionDiabetic Nephropathies1
4Active Not RecruitingTreatmentAnemias / Erythrocyte Transfusion / Renal Dialysis / Renal Insufficiency,Chronic1
4CompletedNot AvailableAnemias1
4CompletedNot AvailableAnemias / Neoplasms2
4CompletedBasic ScienceHypertensive / Thrombosis1
4CompletedPreventionOther and unspecified effects of high altitude1
4CompletedPreventionPatients Receiving a Kidney From a Non-Heart-Beating Donor1
4CompletedTreatmentAnemias9
4CompletedTreatmentAnemias / Cancer treatment / Cancers1
4CompletedTreatmentAnemias / Chronic Renal Failure (CRF)1
4CompletedTreatmentAnemias / Infection, Human Immunodeficiency Virus1
4CompletedTreatmentAnemias / Neoplasms2
4CompletedTreatmentAnemias / Cancer treatment1
4CompletedTreatmentChronic Hepatitis C (CHC)1
4CompletedTreatmentChronic Renal Failure (CRF)1
4CompletedTreatmentDelayed Graft Function1
4CompletedTreatmentSynovitis of osteoarthritis1
4Not Yet RecruitingTreatmentHeart Failure (HF)1
4RecruitingTreatmentAcute Myocardial Infarction (AMI)1
4RecruitingTreatmentAnemias / Hematopoietic Stem Cell Transplantation (HSCT) / Lymphoma NOS1
4RecruitingTreatmentChronic Hepatitis C (CHC)1
4RecruitingTreatmentMyelodysplastic Syndromes1
4TerminatedPreventionContrast Induced Nephropathy (CIN)1
4TerminatedTreatmentAnemias6
4TerminatedTreatmentAnemias / Cancer treatment / Cancers1
4TerminatedTreatmentAnemias / Chronic Renal Insufficiency1
4TerminatedTreatmentAnemias / Hepatitis C Virus (HCV) / Infection, Human Immunodeficiency Virus / Neutropenias1
4TerminatedTreatmentAnemias / Kidney Diseases1
4TerminatedTreatmentAnemias / Renal Failure, Chronic Renal Failure1
4TerminatedTreatmentSubarachnoid Hemorrhage1
4TerminatedTreatmentSurgical Hemostasis1
Not AvailableCompletedNot AvailableAnemia, Neoplasms1
Not AvailableCompletedNot AvailableChronic Renal Failure (CRF)1
Not AvailableCompletedBasic ScienceInsulin Sensitivity1
Not AvailableCompletedSupportive CareMultiple Myeloma (MM)1
Not AvailableCompletedTreatmentAnemias / Infant, Low Birth Weight1
Not AvailableCompletedTreatmentBlood Transfusions1
Not AvailableCompletedTreatmentCardiovascular Diseases / Chronic Diseases / Kidney Diseases1
Not AvailableCompletedTreatmentCrohn's Disease (CD)1
Not AvailableCompletedTreatmentCytopenias / Infection, Human Immunodeficiency Virus8
Not AvailableCompletedTreatmentHypoglycemia / Type 1 Diabetes Mellitus (T1DM)1
Not AvailableCompletedTreatmentLeukemias1
Not AvailableNot Yet RecruitingNot AvailableAnemias / End Stage Renal Failure1
Not AvailableRecruitingNot AvailableAllogenic Transfusion / Hip Arthroplasty / Knee Replacement Surgery / Perioperative Anaemia1
Not AvailableRecruitingBasic ScienceIron Metabolism Disorders1
Not AvailableRecruitingScreeningRetinopathy of Prematurity1
Not AvailableTerminatedTreatmentAnemias1
Not AvailableTerminatedTreatmentIron-Deficiency Anemias1
Not AvailableWithdrawnTreatmentAnemias1
PharmacodynamicsUsed in the treatment of anemia. Involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass.
Mechanism of actionBinding of erythropoietin to the erythropoietin receptor leads to receptor dimerization, which facilitates activation of JAK-STAT signaling pathways within the cytosol. Activated STAT (signal transducers and activators of transcription) proteins are then translocated to the nucleus where they serve as transcription factors which regulate the activation of specific genes involved in cell division or differentiation.
TargetKindPharmacological actionActionsOrganismUniProt ID
Erythropoietin receptorProteinyes
agonist
HumanP19235 details
Related Articles
AbsorptionNot Available
Volume of distributionNot Available
Protein bindingNot Available
MetabolismNot Available
Route of eliminationNot Available
Half lifeNot Available
Clearance
  • 20.2 +/- 15.9 mL/h/kg [150 Units/kg SC TIW, Week 1 when anemic cancer patients were receiving chemotherapy]
  • 23.6 +/- 9.5 mL/h/kg [150 Units/kg SC TIW, Week 3 when anemic cancer patients were not receiving chemotherapy]
  • 9.2 +/- 4.7 mL/h/kg [40,000 Units/kg SC TIW, Week 1 when anemic cancer patients were receiving chemotherapy]
  • 13.9 +/- 7.6 mL/h/kg [40,000 Units/kg SC TIW, Week 3 when anemic cancer patients were not receiving chemotherapy]
ToxicityNot Available
Affected organisms
  • Humans and other mammals
PathwaysNot Available
SNP Mediated EffectsNot Available
SNP Mediated Adverse Drug ReactionsNot Available
Interactions
Drug Interactions
DrugInteractionDrug group
LenalidomideErythropoietin may increase the thrombogenic activities of Lenalidomide.Approved
Nandrolone decanoateNandrolone decanoate may increase the stimulatory activities of Erythropoietin.Approved, Illicit
Nandrolone phenpropionateNandrolone phenpropionate may increase the stimulatory activities of Erythropoietin.Approved, Illicit
ThalidomideErythropoietin may increase the thrombogenic activities of Thalidomide.Approved, Investigational, Withdrawn
Food InteractionsNot Available
References
Synthesis ReferenceNot Available
General ReferencesNot Available
External Links
ATC CodesB03XA01
AHFS Codes
  • 20:16.00
PDB Entries
FDA labelDownload (2.73 MB)
MSDSNot Available
Pharmacoeconomics
ManufacturersNot Available
Packagers
Dosage forms
FormRouteStrength
Injection, solutionIntravenous; Subcutaneous1000 IU/0.5ml
Injection, solutionIntravenous; Subcutaneous10000 IU/1.0ml
Injection, solutionIntravenous; Subcutaneous2000 IU/1.0ml
Injection, solutionIntravenous; Subcutaneous20000 IU/0.5ml
Injection, solutionIntravenous; Subcutaneous3000 IU/0.3ml
Injection, solutionIntravenous; Subcutaneous30000 IU/0.75ml
Injection, solutionIntravenous; Subcutaneous4000 IU/0.4ml
Injection, solutionIntravenous; Subcutaneous40000 IU/1ml
Injection, solutionIntravenous; Subcutaneous40000 IU/1.0ml
Injection, solutionIntravenous; Subcutaneous5000 IU/0.5ml
Injection, solutionIntravenous; Subcutaneous6000 IU/0.6ml
Injection, solutionIntravenous; Subcutaneous7000 IU/0.7ml
Injection, solutionIntravenous; Subcutaneous8000 IU/0.8ml
Injection, solutionIntravenous; Subcutaneous9000 IU/0.9ml
Injection, solutionIntravenous; Subcutaneous10000 IU/1ml
SolutionIntravenous; Subcutaneous10000 [iU]/mL
SolutionIntravenous; Subcutaneous2000 [iU]/mL
SolutionIntravenous; Subcutaneous20000 [iU]/mL
SolutionIntravenous; Subcutaneous3000 [iU]/mL
SolutionIntravenous; Subcutaneous4000 [iU]/mL
Injection, solutionIntravenous; Subcutaneous2000 IU/0.5ml
Injection, solutionIntravenous; Subcutaneous20000 IU/1.0ml
Injection, solutionIntravenous; Subcutaneous3000 IU/0.5ml
Injection, solutionIntravenous; Subcutaneous30000 IU/1.0ml
Injection, solutionIntravenous; Subcutaneous4000 IU/0.5ml
SolutionIntravenous; Subcutaneous20000 unit
SolutionIntravenous; Subcutaneous30000 unit
SolutionIntravenous; Subcutaneous10000 unit
SolutionIntravenous; Subcutaneous1000 unit
SolutionIntravenous; Subcutaneous2000 unit
SolutionIntravenous; Subcutaneous3000 unit
SolutionIntravenous; Subcutaneous40000 unit
SolutionIntravenous; Subcutaneous4000 unit
SolutionIntravenous; Subcutaneous5000 unit
SolutionIntravenous; Subcutaneous6000 unit
SolutionIntravenous; Subcutaneous8000 unit
Injection, solutionIntravenous; Subcutaneous10000 [iU]/mL
Injection, solutionIntravenous; Subcutaneous2000 [iU]/mL
Injection, solutionIntravenous; Subcutaneous20000 [iU]/mL
Injection, solutionIntravenous; Subcutaneous3000 [iU]/mL
Injection, solutionIntravenous; Subcutaneous4000 [iU]/mL
Injection, solutionIntravenous; Subcutaneous40000 [iU]/mL
Prices
Unit descriptionCostUnit
Epogen 40000 unit/ml Solution 1 Box Contains Ten 1ml Vials6852.3USD box
Epogen 20000 unit/ml Solution 1 Box Contains Ten 1ml Vials3157.44USD box
Epogen 10000 unit/ml Solution 1 Box Contains Ten 1ml Vials1578.72USD box
Procrit 40000 unit/ml vial767.03USD vial
Procrit 10000 unit/ml vial710.87USD vial
Epogen 40000 unit/ml vial640.37USD ml
Procrit 20000 unit/ml vial388.97USD ml
Procrit 20000 unit/ml Solution378.14USD ml
Procrit 10000 unit/ml Solution 2ml Vial358.02USD vial
Epogen 10000 unit/ml Solution 2ml Vial315.74USD vial
Epogen 20000 unit/ml vial303.6USD ml
Epogen 10000 unit/ml vial151.8USD ml
Procrit 4000 unit/ml vial74.17USD vial
Epogen 4000 unit/ml vial61.34USD vial
Procrit 3000 unit/ml vial55.63USD vial
Epogen 3000 unit/ml vial47.53USD vial
Procrit 2000 unit/ml vial37.09USD vial
Epogen 2000 unit/ml vial34.14USD vial
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
CA1339047 No1997-05-272014-05-27Canada
Properties
StateLiquid
Experimental Properties
PropertyValueSource
melting point53 °CArakawa, T. et al., Biosci. Biotechnol. Biochem. 65:1321-1327 (2001)
isoelectric point8.75Not Available
Taxonomy
DescriptionNot Available
KingdomOrganic Compounds
Super ClassOrganic Acids
ClassCarboxylic Acids and Derivatives
Sub ClassAmino Acids, Peptides, and Analogues
Direct ParentPeptides
Alternative ParentsNot Available
SubstituentsNot Available
Molecular FrameworkNot Available
External DescriptorsNot Available

Targets

Kind
Protein
Organism
Human
Pharmacological action
yes
Actions
agonist
General Function:
Identical protein binding
Specific Function:
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
Gene Name:
EPOR
Uniprot ID:
P19235
Molecular Weight:
55064.725 Da
References
  1. LaMontagne KR, Butler J, Marshall DJ, Tullai J, Gechtman Z, Hall C, Meshaw A, Farrell FX: Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor-positive breast carcinoma models. Mol Cancer Ther. 2006 Feb;5(2):347-55. [PubMed:16505108 ]
  2. Kokhaei P, Abdalla AO, Hansson L, Mikaelsson E, Kubbies M, Haselbeck A, Jernberg-Wiklund H, Mellstedt H, Osterborg A: Expression of erythropoietin receptor and in vitro functional effects of epoetins in B-cell malignancies. Clin Cancer Res. 2007 Jun 15;13(12):3536-44. [PubMed:17575216 ]
  3. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
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Drug created on June 13, 2005 07:24 / Updated on August 17, 2016 12:23