Expectorants

Name
Expectorants
Accession Number
DBCAT000852
Description

Agents that increase mucous excretion. Mucolytic agents, that is drugs that liquefy mucous secretions, are also included here.

ATC Classification
Drugs
DrugDrug Description
GuaifenesinAn expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.
SteproninStrepronin is a mucolytic (expectorant) drug.
CarbocisteineUsed to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis.
ErdosteineFro the treatment of chronic bronchitis in adults.
AmbroxolAmbroxol is indicated for secretolytic therapy in bronchoplmonary diseaes with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing.
LetosteineLetosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions.
EprazinoneEprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms.
BromhexineBromhexine is an expectorant/mucolytic agent. Bromhexine is not available in the United States. It is marketed under the trade name Bisolvon(R) in Germany, England, Belgium, France, Italy, Netherlands, Norway, Sweden,...
SobrerolNot Annotated
AcetylcysteineA medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose.
Potassium citrateAn agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.
Terpin hydrateAn expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract.
CitioloneNot Annotated
GuacetisalNot Annotated
Dornase alfaA synthetic form of human deoxyribonuclease I used to break down extracellular DNA in the lungs, a major source of mucous viscosity in cystic fibrosis.
MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, and to measure glomerular filtration rate.
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
TyloxapolTyloxapol is an inhaled surfactant that assists in removing and liquefying and removing bronchopulmonary secretions with mucus and pus. Tyloxapol is administered either through nebulized solution or a stream of...
Hedera helix leaf extractAn extract from Hedera helix leaf extract used in allergy testing.
NeltenexineNeltenexine is an elastase inhibitor. It may be useful for preventing pulmonary emphysema.
Wood creosoteNot Annotated
IpecacAn emetic agent used to induce vomiting in poisoning.
LevoverbenoneNot Annotated
Antimony pentasulfideNot Annotated
Althea rootNot Annotated
DomiodolNot Annotated
DextromethorphanAn NMDA receptor antagonist used to treat cases of dry cough.
Potassium IodideAn oral antithyroid agent used for the prevention of radioactive iodine uptake into the thyroid gland during a nuclear radiation emergency.
Coenzyme MA uroprotective agent used for the reduction and prophylaxis of oxazaphosphorine-induced toxicity in the urinary tract.
Polygala senega rootNot Annotated
Drugs & Drug Targets
DrugTargetType
GuaifenesinNMDA receptortarget
CarbocisteineGlutathione S-transferase Ptarget
ErdosteineAdenosine deaminaseenzyme
AmbroxolCytochrome P450 3A4enzyme
AcetylcysteineSolute carrier organic anion transporter family member 1B1transporter
AcetylcysteineNAPQI (N-acetyl-p-benzoquinone imine)target
AcetylcysteineSolute carrier family 22 member 6transporter
AcetylcysteineAminoacylase-1target
AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
AcetylcysteineInhibitor of nuclear factor kappa-B kinase subunit betatarget
AcetylcysteineGlutathione synthetasetarget
AcetylcysteineCystine/glutamate transportertarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 2Btarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 1target
AcetylcysteineGlutamate receptor ionotropic, NMDA 2Atarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 2Dtarget
AcetylcysteineGlutamate receptor ionotropic, NMDA 3Atarget
Dornase alfaDNAtarget
MannitolMannitol dehydrogenaseenzyme
TyloxapolLipoprotein lipasetarget
IpecacCytochrome P450 2D6enzyme
IpecacCytochrome P450 3A4enzyme
DextromethorphanSigma non-opioid intracellular receptor 1target
DextromethorphanHCG20471, isoform CRA_ctarget
DextromethorphanNeuronal acetylcholine receptor subunit alpha-2target
DextromethorphanSodium-dependent serotonin transportertarget
DextromethorphanGlutamate receptor ionotropic, NMDA 3Atarget
DextromethorphanCytochrome P450 2D6enzyme
DextromethorphanCytochrome P450 3A4enzyme
DextromethorphanCytochrome P450 3A7enzyme
DextromethorphanCytochrome P450 2C9enzyme
DextromethorphanCytochrome P450 2B6enzyme
DextromethorphanCytochrome P450 2C19enzyme
DextromethorphanMembrane-associated progesterone receptor component 1target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-3target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-4target
DextromethorphanNeuronal acetylcholine receptor subunit beta-4target
DextromethorphanNeuronal acetylcholine receptor subunit beta-2target
DextromethorphanNeuronal acetylcholine receptor subunit alpha-7target
DextromethorphanMu-type opioid receptortarget
DextromethorphanDelta-type opioid receptortarget
DextromethorphanKappa-type opioid receptortarget
DextromethorphanNADPH oxidasetarget
DextromethorphanSodium-dependent noradrenaline transportertarget
Potassium IodideTyrosinetarget
Coenzyme MGlutathione reductase, mitochondrialenzyme