DrugDrug NameDrug Description
DB01003Cromoglicic acidA medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions.
DB01094HesperetinFor lowering cholesterol and, possibly, otherwise favorably affecting lipids. In vitro research also suggests the possibility that hesperetin might have some anticancer effects and that it might have some anti-aromatase...
DB01148FlavoxateA muscarinic antagonist and spasmolytic used for the symptomatic relief of conditions associated with lack of muscle control in the bladder, such as dysuria, urgency, and nocturia.
DB01645GenisteinCurrently Genistein is being studied in clinical trials as a treatment for prostate cancer.
DB01698RutinA flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
DB02115DaidzinNot Available
DB02375MyricetinNot Available
DB03467NaringeninNot Available
DB03496AlvocidibInvestigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified).
DB03823EpigallocatechinNot Available
DB04216QuercetinQuercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
DB044294'-HydroxyflavanoneNot Available
DB04703HesperidinA bioflavonoid found in a variety of nutritional supplements that is touted to have various beneficial effects on blood vessel disorders and various other conditions.
DB04915IdronoxilIntended for the treatment of various forms of cancer.
DB04941CrofelemerAn antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
DB05187ElafibranorInvestigated for use/treatment in atherosclerosis and diabetes mellitus type 2.
DB05197SofalconeInvestigated for use/treatment in gastroenteritis and ulcers.
DB06588TriphendiolInvestigated for use/treatment in cancer/tumors (unspecified).
DB06732beta-Naphthoflavoneβ-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.
DB07352ApigeninNot Available
DB07776FlavoneNot Available
DB08995DiosminDiosmin is a semisynthetic drug indicated for the treatment of venous disease. Diosmin is a flavone that can be found in the plant Teucrium gnaphalodes. Diosmin is available as a...
DB11259DiosmetinDiosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits . Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant,...
DB11457RotenoneRotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also...
DB11674EquolEquol has been used in trials studying the treatment of Breast Cancer.
DB12039EpicatechinEpicatechin has been used in trials studying the treatment of Pre-diabetes.
DB12052IcariinIcariin has been investigated for the basic science of the Pharmacokinetic Profile of Icariin in Humans.
DB12058RecoflavoneRecoflavone has been used in trials studying the treatment of Acute Gastritis, Dry Eye Syndrome, and Chronic Gastritis.
DB12116Epigallocatechin gallateEpigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
DB12290PuerarinPuerarin has been investigated for the treatment of Alcohol Abuse.
DB12665IsoquercetinIsoquercetin has been used in trials studying the treatment of Kidney Cancer, Renal cell carcinoma, Advanced Renal Cell Carcinoma, Thromboembolism of Vein in Pancreatic Cancer, and Thromboembolism of Vein VTE...
DB12672IcaritinIcaritin has been used in trials studying the treatment of Solid Tumors, Metastatic Breast Cancer, and Hepatocellular Carcinoma (HCC).
DB13062ME-344ME-344 has been used in trials studying the treatment of Solid Tumors.
DB13124TroxerutinTroxerutin has been used in trials studying the treatment of Chronic Venous Insufficiency.
DB13182DaidzeinNot Annotated
DB13333EfloxateNot Annotated
DB13482DimeflineNot Annotated
DB13490HidrosminNot Annotated
DB13618IpriflavoneNot Annotated
DB14008HispidulinHispidulin (4',5,7-trihydroxy-6-methoxyflavone) is a potent benzodiazepine (BZD) receptor ligand with positive allosteric properties .
DB14086CianidanolAn antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.
DB14122DihydroxymethoxychalconeCardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits to human...
DB14586Citrus bioflavonoidsNot Annotated
DB02224TaxifolinNot Available
DB032852',4,4'-TrihydroxychalconeNot Available
DB07795FisetinNot Available
DB09298SilibininCurrently being tested as a treatment of severe intoxications with hepatotoxic substances, such as death cap (Amanita phalloides) poisoning.
DB15334Biochanin ABiochanin A is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
DB15335FormononetinFormononetin is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
DB15359XanthohumolXanthohumol is under investigation in clinical trial NCT01367431 (Xanthohumol and Metabolic Syndrome).
DB02709ResveratrolBeing investigated for the treatment of Herpes labialis infections (cold sores).
DB05073SRT501Investigated for use/treatment in diabetes mellitus type 2 and neurologic disorders.
DB15581ChrysinNot Annotated
DB15584LuteolinNot Annotated
DrugDrug NameTargetType
DB01003Cromoglicic acidCalcium-activated potassium channel subunit alpha-1target
DB01003Cromoglicic acidProtein S100-Ptarget
DB01094HesperetinMicrosomal triglyceride transfer protein large subunittarget
DB01094HesperetinSterol O-acyltransferase 1target
DB01094HesperetinSterol O-acyltransferase 2target
DB01094HesperetinCytochrome P450 1A2enzyme
DB01094HesperetinATP-binding cassette sub-family G member 2transporter
DB01094HesperetinSex hormone-binding globulintarget
DB01148FlavoxateMuscarinic acetylcholine receptor M1target
DB01148FlavoxateMuscarinic acetylcholine receptor M2target
DB01645GenisteinEstrogen receptor betatarget
DB01645GenisteinDNA topoisomerase 2-alphatarget
DB01645GenisteinProtein-tyrosine kinase 2-betatarget
DB01645GenisteinP-glycoprotein 1transporter
DB01645GenisteinMultidrug resistance-associated protein 1transporter
DB01645GenisteinATP-binding cassette sub-family G member 2transporter
DB01645GenisteinCytochrome P450 1A2enzyme
DB01645GenisteinNuclear receptor coactivator 1target
DB01645GenisteinEstrogen receptor alphatarget
DB01645GenisteinNuclear receptor coactivator 2target
DB01645GenisteinTransthyretincarrier
DB01645GenisteinSteroid hormone receptor ERR2target
DB01645GenisteinSteroid hormone receptor ERR1target
DB01645GenisteinNuclear receptor subfamily 1 group I member 2target
DB01645GenisteinRAC-alpha serine/threonine-protein kinasetarget
DB01645GenisteinG-protein coupled estrogen receptor 1target
DB01645GenisteinCytochrome P450 1B1target
DB01645GenisteinSex hormone-binding globulintarget
DB01645GenisteinCytochrome P450 1A1enzyme
DB01645GenisteinSolute carrier organic anion transporter family member 1B1transporter
DB01645GenisteinSolute carrier organic anion transporter family member 2B1transporter
DB01645GenisteinCytochrome P450 2C8enzyme
DB01645GenisteinCytochrome P450 2C9enzyme
DB01645GenisteinCytochrome P450 3A1enzyme
DB01645GenisteinCytochrome P450 3A2enzyme
DB01645GenisteinCytochrome P450 3A4enzyme
DB01698RutinAldo-keto reductase family 1 member C3target
DB01698RutinCytochrome P450 3A4enzyme
DB01698RutinCarbonyl reductase [NADPH] 1target
DB02115DaidzinAldehyde dehydrogenase, mitochondrialtarget
DB02115DaidzinATP-binding cassette sub-family G member 2transporter
DB02375MyricetinPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
DB02375MyricetinMultidrug resistance-associated protein 1transporter
DB02375MyricetinTyrosine-protein kinase JAK1target
DB03467NaringeninSolute carrier organic anion transporter family member 2B1transporter
DB03467NaringeninP-glycoprotein 1transporter
DB03467NaringeninMultidrug resistance-associated protein 1transporter
DB03467NaringeninATP-binding cassette sub-family G member 2transporter
DB03467NaringeninHTH-type transcriptional regulator TtgRtarget
DB03467NaringeninEstrogen receptor alphatarget
DB03467NaringeninAldo-keto reductase family 1 member C1target
DB03467NaringeninCytochrome P450 1B1target
DB03467NaringeninKAT8 regulatory NSL complex subunit 3target
DB03467NaringeninSex hormone-binding globulintarget
DB03467NaringeninCytochrome P450 19A1target
DB03467NaringeninEstrogen receptor betatarget
DB03496AlvocidibGlycogen phosphorylase, muscle formtarget
DB03496AlvocidibCyclin-dependent kinase 7target
DB03496AlvocidibCyclin-dependent kinase 5target
DB03496AlvocidibCyclin-dependent kinase 9target
DB03496AlvocidibCyclin-dependent kinase 1target
DB03496AlvocidibCyclin-dependent kinase 6target
DB03496AlvocidibEpidermal growth factor receptortarget
DB03496AlvocidibCyclin-dependent kinase 4target
DB03496AlvocidibCyclin-dependent kinase 8target
DB03496AlvocidibCyclin-dependent kinase 2target
DB03496AlvocidibATP-binding cassette sub-family G member 2transporter
DB03496AlvocidibGlycogen phosphorylase, brain formtarget
DB03496AlvocidibGlycogen phosphorylase, liver formtarget
DB03496AlvocidibUDP-glucuronosyltransferase 1-1enzyme
DB04216QuercetinTyrosine-protein kinase HCKtarget
DB04216QuercetinCytochrome P450 2C8enzyme
DB04216QuercetinMultidrug resistance-associated protein 1transporter
DB04216QuercetinCanalicular multispecific organic anion transporter 1transporter
DB04216QuercetinMonocarboxylate transporter 2transporter
DB04216QuercetinSolute carrier organic anion transporter family member 2B1transporter
DB04216QuercetinP-glycoprotein 1transporter
DB04216QuercetinMonocarboxylate transporter 1transporter
DB04216QuercetinATP-binding cassette sub-family G member 2transporter
DB04216QuercetinPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
DB04216QuercetinUDP-glucuronosyltransferase 3A1target
DB04216QuercetinATP synthase subunit alpha, mitochondrialtarget
DB04216QuercetinATP synthase subunit beta, mitochondrialtarget
DB04216QuercetinATP synthase subunit gamma, mitochondrialtarget
DB04216QuercetinSerine/threonine-protein kinase pim-1target
DB04216QuercetinHTH-type transcriptional regulator TtgRtarget
DB04216Quercetin3-hydroxyisobutyryl-CoA hydrolase, mitochondrialtarget
DB04216Quercetin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
DB04216QuercetinSerine/threonine-protein kinase 17Btarget
DB04216QuercetinEstrogen receptor alphatarget
DB04216QuercetinEstrogen receptor betatarget
DB04216QuercetinRibosyldihydronicotinamide dehydrogenase [quinone]target
DB04216QuercetinSerum albumincarrier
DB04216QuercetinAryl hydrocarbon receptortarget
DB04216QuercetinCytochrome P450 1B1target
DB04216QuercetinActin, cytoplasmic 1target
DB04216QuercetinCasein kinase II subunit alphatarget
DB04216QuercetinCasein kinase II subunit betatarget
DB04216QuercetinEukaryotic translation initiation factor 3 subunit Ftarget
DB04216QuercetinHeat shock protein HSP 90-alphatarget
DB04216QuercetinHeat shock-related 70 kDa protein 2target
DB04216QuercetinRuvB-like 2target
DB04216QuercetinSplicing factor 3B subunit 3target
DB04216QuercetinUbiquitin-like modifier-activating enzyme 1target
DB04216QuercetinSex hormone-binding globulintarget
DB04216QuercetinCarbonyl reductase [NADPH] 1target
DB04216QuercetinCCAAT/enhancer-binding protein betatarget
DB04216QuercetinNuclear receptor subfamily 1 group I member 2target
DB04216QuercetinSolute carrier organic anion transporter family member 1B1transporter
DB044294'-HydroxyflavanoneSex hormone-binding globulintarget
DB04703HesperidinAurora kinase Btarget
DB04915IdronoxilEcto-NOX disulfide-thiol exchanger 2target
DB04941CrofelemerCystic fibrosis transmembrane conductance regulatortarget
DB04941CrofelemerAnoctamin-1target
DB05187ElafibranorPeroxisome proliferator-activated receptor alphatarget
DB05187ElafibranorPeroxisome proliferator-activated receptor deltatarget
DB05187ElafibranorPeroxisome proliferator-activated receptor gammatarget
DB05197SofalconeCarbonyl reductase [NADPH] 1enzyme
DB06732beta-NaphthoflavoneCytochrome P450 1A2enzyme
DB06732beta-NaphthoflavoneEstrogen receptor alphatarget
DB06732beta-NaphthoflavoneSteroid hormone receptor ERR1target
DB06732beta-NaphthoflavoneCOUP transcription factor 1target
DB06732beta-NaphthoflavoneAryl hydrocarbon receptortarget
DB06732beta-NaphthoflavoneCytochrome P450 1B1target
DB07352Apigenin3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZtarget
DB07776FlavoneNeocarzinostatintarget
DB07776FlavoneSteroid hormone receptor ERR1target
DB07776FlavoneSteroid hormone receptor ERR2target
DB07776FlavoneCytochrome P450 1B1target
DB08995DiosminAryl hydrocarbon receptortarget
DB11674EquolEstrogen receptor betatarget
DB11674EquolSex hormone-binding globulintarget
DB12116Epigallocatechin gallateAryl hydrocarbon receptortarget
DB12116Epigallocatechin gallateDNA (cytosine-5)-methyltransferase 1target
DB12116Epigallocatechin gallateDihydrofolate reductase, mitochondrialtarget
DB07795FisetinCyclin homologtarget
DB07795FisetinCyclin-dependent kinase 6target
DB09298SilibininSolute carrier family 22 member 6transporter
DB09298SilibininUDP-glucuronosyltransferase 1-1enzyme
DB09298SilibininSolute carrier organic anion transporter family member 1B1transporter
DB09298SilibininSolute carrier organic anion transporter family member 1B3transporter
DB09298SilibininSolute carrier organic anion transporter family member 2B1transporter
DB02709ResveratrolTransthyretincarrier
DB02709ResveratrolRibosyldihydronicotinamide dehydrogenase [quinone]target
DB02709ResveratrolProstaglandin G/H synthase 1target
DB02709ResveratrolCasein kinase II subunit alphatarget
DB02709ResveratrolProstaglandin G/H synthase 2target
DB02709ResveratrolCytochrome P450 1A1enzyme
DB02709ResveratrolCytochrome P450 3A4enzyme
DB02709ResveratrolCytochrome P450 1A2enzyme
DB02709ResveratrolCytochrome P450 1B1enzyme
DB02709ResveratrolArachidonate 15-lipoxygenasetarget
DB02709ResveratrolArachidonate 5-lipoxygenasetarget
DB02709ResveratrolAryl hydrocarbon receptortarget
DB02709ResveratrolPhosphatidylinositol 4-kinase type 2-betatarget
DB02709ResveratrolIntegrin alpha-5target
DB02709ResveratrolIntegrin beta-3target
DB02709ResveratrolSerum albumincarrier
DB02709ResveratrolAmyloid beta A4 proteintarget
DB02709ResveratrolAlpha-synucleintarget
DB02709ResveratrolEstrogen receptor alphatarget
DB02709ResveratrolMelatonin receptor type 1Atarget
DB02709ResveratrolMelatonin receptor type 1Btarget
DB02709ResveratrolC-type lectin domain family 14 member Atarget
DB02709ResveratrolNuclear receptor subfamily 1 group I member 2target
DB02709ResveratrolNuclear receptor subfamily 1 group I member 3target
DB02709ResveratrolSolute carrier family 2, facilitated glucose transporter member 1target
DB02709ResveratrolCarbonyl reductase [NADPH] 1target
DB02709ResveratrolPeroxisome proliferator-activated receptor alphatarget
DB02709ResveratrolPeroxisome proliferator-activated receptor gammatarget
DB02709ResveratrolRAC-alpha serine/threonine-protein kinasetarget
DB02709ResveratrolFar upstream element-binding protein 2target
DB02709ResveratrolTyrosine--tRNA ligase, cytoplasmictarget
DB05073SRT501NAD-dependent protein deacetylase sirtuin-1target