Showing BioInteractions for Gabexate (DB12831)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Gabexate is a Plasma kallikrein inhibitor | ||
| 1 | Plasma kallikrein inhibitors | Berotralstat, Conestat alfa, Ecallantide, Human C1-esterase inhibitor, Lanadelumab, Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Gabexate is a Prothrombin inhibitor | ||
| 1 | Prothrombin inhibitors | Antithrombin Alfa, Argatroban, Betrixaban, Bivalirudin, Conestat alfa, Dabigatran etexilate, Human C1-esterase inhibitor, Lepirudin, Nafamostat, Suramin, Thrombomodulin Alfa, Ximelagatran |
| 2 | Prothrombin activators | Antihemophilic factor, human recombinant, Lonoctocog alfa, Menadione, Moroctocog alfa |
| 3 | Prothrombin agonists | Anti-inhibitor coagulant complex, Kappadione |
| 4 | Prothrombin substrates | Anti-inhibitor coagulant complex |
| 5 | Prothrombin binders | Turoctocog alfa, Turoctocog alfa pegol |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Gabexate is a Plasminogen inhibitor | ||
| 1 | Plasminogen inhibitors | Aminocaproic acid, Tranexamic acid |
| 2 | Plasminogen activators | Alteplase, Anistreplase, Reteplase, Streptokinase, Tenecteplase, Urokinase |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Gabexate is a Trypsin-1 inhibitor | ||
| 1 | Trypsin-1 inhibitors | Camostat, Nafamostat, RWJ-56423 |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Gabexate is a Complement C1s subcomponent inhibitor | ||
| 1 | Complement C1s subcomponent inhibitors | Conestat alfa, Human C1-esterase inhibitor |
| 2 | Complement C1s subcomponent modulators | Zinc chloride, Zinc sulfate, unspecified form |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Gabexate is a Complement C1r subcomponent inhibitor | ||
| 1 | Complement C1r subcomponent inhibitors | Conestat alfa, Human C1-esterase inhibitor |
| 2 | Complement C1r subcomponent modulators | Zinc chloride, Zinc sulfate, unspecified form |