Fluindione

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Fluindione
Accession Number
DB13136
Type
Small Molecule
Groups
Investigational
Description

Fluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior. Fluindione has been investigated for the treatment of Blood Coagulation Disorders.

Structure
Thumb
Synonyms
Not Available
Categories
UNII
EQ35YMS20Q
CAS number
957-56-2
Weight
Average: 240.233
Monoisotopic: 240.058657693
Chemical Formula
C15H9FO2
InChI Key
NASXCEITKQITLD-UHFFFAOYSA-N
InChI
InChI=1S/C15H9FO2/c16-10-7-5-9(6-8-10)13-14(17)11-3-1-2-4-12(11)15(13)18/h1-8,13H
IUPAC Name
2-(4-fluorophenyl)-2,3-dihydro-1H-indene-1,3-dione
SMILES
FC1=CC=C(C=C1)C1C(=O)C2=CC=CC=C2C1=O

Pharmacology

Indication
Not Available
Structured Indications
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
AbciximabAbciximab may increase the anticoagulant activities of Fluindione.Approved
AceclofenacAceclofenac may increase the anticoagulant activities of Fluindione.Approved
AcemetacinAcemetacin may increase the anticoagulant activities of Fluindione.Experimental
AcenocoumarolAcenocoumarol may increase the anticoagulant activities of Fluindione.Approved
AcetaminophenAcetaminophen may increase the anticoagulant activities of Fluindione.Approved
AcetohexamideAcetohexamide may increase the anticoagulant activities of Fluindione.Withdrawn
Acetylsalicylic acidAcetylsalicylic acid may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
AdapaleneAdapalene may increase the anticoagulant activities of Fluindione.Approved
AlaproclateAlaproclate may increase the anticoagulant activities of Fluindione.Experimental
AlclofenacAlclofenac may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
AllopurinolAllopurinol may increase the anticoagulant activities of Fluindione.Approved
AllylestrenolThe therapeutic efficacy of Fluindione can be decreased when used in combination with Allylestrenol.Approved
AlminoprofenAlminoprofen may increase the anticoagulant activities of Fluindione.Experimental
AloxiprinAloxiprin may increase the anticoagulant activities of Fluindione.Experimental
AlprostadilAlprostadil may increase the anticoagulant activities of Fluindione.Approved, Investigational
AlteplaseAlteplase may increase the anticoagulant activities of Fluindione.Approved
AltrenogestThe therapeutic efficacy of Fluindione can be decreased when used in combination with Altrenogest.Vet Approved
Aluminium clofibrateAluminium clofibrate may increase the anticoagulant activities of Fluindione.Experimental
ALX-0081ALX-0081 may increase the anticoagulant activities of Fluindione.Investigational
AmdinocillinAmdinocillin may increase the anticoagulant activities of Fluindione.Withdrawn
AmineptineAmineptine may increase the anticoagulant activities of Fluindione.Illicit, Withdrawn
Aminosalicylic AcidAminosalicylic Acid may increase the anticoagulant activities of Fluindione.Approved
AmiodaroneAmiodarone may increase the anticoagulant activities of Fluindione.Approved, Investigational
AmitriptylineAmitriptyline may increase the anticoagulant activities of Fluindione.Approved
AmobarbitalThe metabolism of Fluindione can be increased when combined with Amobarbital.Approved, Illicit
AmoxicillinAmoxicillin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
AmpicillinAmpicillin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
AnagrelideAnagrelide may increase the anticoagulant activities of Fluindione.Approved
AncrodAncrod may increase the anticoagulant activities of Fluindione.Investigational
AndrographolideAndrographolide may increase the anticoagulant activities of Fluindione.Investigational
AnisodamineAnisodamine may increase the anticoagulant activities of Fluindione.Investigational
AnistreplaseAnistreplase may increase the anticoagulant activities of Fluindione.Approved
AntipyrineAntipyrine may increase the anticoagulant activities of Fluindione.Approved
Antithrombin III humanAntithrombin III human may increase the anticoagulant activities of Fluindione.Approved
ApixabanApixaban may increase the anticoagulant activities of Fluindione.Approved
ApocyninApocynin may increase the anticoagulant activities of Fluindione.Investigational
ApremilastApremilast may increase the anticoagulant activities of Fluindione.Approved, Investigational
AprotininThe therapeutic efficacy of Fluindione can be decreased when used in combination with Aprotinin.Approved, Withdrawn
ArdeparinArdeparin may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
ArgatrobanArgatroban may increase the anticoagulant activities of Fluindione.Approved, Investigational
AspoxicillinAspoxicillin may increase the anticoagulant activities of Fluindione.Experimental
AstaxanthinAstaxanthin may increase the anticoagulant activities of Fluindione.Investigational
AtorvastatinAtorvastatin may increase the anticoagulant activities of Fluindione.Approved
AzapropazoneAzapropazone may increase the anticoagulant activities of Fluindione.Withdrawn
AzathioprineAzathioprine may decrease the anticoagulant activities of Fluindione.Approved
AzelastineAzelastine may increase the anticoagulant activities of Fluindione.Approved
AzidocillinAzidocillin may increase the anticoagulant activities of Fluindione.Approved
AzithromycinThe serum concentration of Fluindione can be increased when it is combined with Azithromycin.Approved
AzlocillinAzlocillin may increase the anticoagulant activities of Fluindione.Approved
BacampicillinBacampicillin may increase the anticoagulant activities of Fluindione.Approved
BalsalazideBalsalazide may increase the anticoagulant activities of Fluindione.Approved, Investigational
BarbexacloneThe metabolism of Fluindione can be increased when combined with Barbexaclone.Experimental
BarbitalThe metabolism of Fluindione can be increased when combined with Barbital.Illicit
BatroxobinBatroxobin may increase the anticoagulant activities of Fluindione.Experimental
BecaplerminBecaplermin may increase the anticoagulant activities of Fluindione.Approved, Investigational
BemiparinBemiparin may increase the anticoagulant activities of Fluindione.Approved
BendazacBendazac may increase the anticoagulant activities of Fluindione.Experimental
BenorilateBenorilate may increase the anticoagulant activities of Fluindione.Experimental
BenoxaprofenBenoxaprofen may increase the anticoagulant activities of Fluindione.Withdrawn
Benzathine benzylpenicillinBenzathine benzylpenicillin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
BenzylpenicillinBenzylpenicillin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
Benzylpenicilloyl PolylysineBenzylpenicilloyl Polylysine may increase the anticoagulant activities of Fluindione.Approved
BeraprostBeraprost may increase the anticoagulant activities of Fluindione.Investigational
BevoniumBevonium may increase the anticoagulant activities of Fluindione.Experimental
BezafibrateBezafibrate may increase the anticoagulant activities of Fluindione.Approved
BicalutamideThe serum concentration of Fluindione can be increased when it is combined with Bicalutamide.Approved
BivalirudinBivalirudin may increase the anticoagulant activities of Fluindione.Approved, Investigational
BosentanThe metabolism of Fluindione can be increased when combined with Bosentan.Approved, Investigational
BrinaseBrinase may increase the anticoagulant activities of Fluindione.Experimental
BromfenacBromfenac may increase the anticoagulant activities of Fluindione.Approved
BucillamineBucillamine may increase the anticoagulant activities of Fluindione.Investigational
BufexamacBufexamac may increase the anticoagulant activities of Fluindione.Experimental
BuflomedilBuflomedil may increase the anticoagulant activities of Fluindione.Experimental
BumadizoneBumadizone may increase the anticoagulant activities of Fluindione.Experimental
ButylphthalideButylphthalide may increase the anticoagulant activities of Fluindione.Investigational
CangrelorCangrelor may increase the anticoagulant activities of Fluindione.Approved
CapecitabineThe serum concentration of Fluindione can be increased when it is combined with Capecitabine.Approved, Investigational
CarbamazepineThe serum concentration of Fluindione can be decreased when it is combined with Carbamazepine.Approved, Investigational
Carbaspirin calciumCarbaspirin calcium may increase the anticoagulant activities of Fluindione.Experimental
CarbenicillinCarbenicillin may increase the anticoagulant activities of Fluindione.Approved
Carbenicillin indanylCarbenicillin indanyl may increase the anticoagulant activities of Fluindione.Approved
CarbimazoleCarbimazole may decrease the anticoagulant activities of Fluindione.Approved
CarbomycinThe serum concentration of Fluindione can be increased when it is combined with Carbomycin.Vet Approved
CarbutamideCarbutamide may increase the anticoagulant activities of Fluindione.Experimental
CarfecillinCarfecillin may increase the anticoagulant activities of Fluindione.Experimental
CarprofenCarprofen may increase the anticoagulant activities of Fluindione.Approved, Vet Approved, Withdrawn
CastanospermineCastanospermine may increase the anticoagulant activities of Fluindione.Experimental
CefacetrileCefacetrile may increase the anticoagulant activities of Fluindione.Approved
CefaclorCefaclor may increase the anticoagulant activities of Fluindione.Approved
CefadroxilCefadroxil may increase the anticoagulant activities of Fluindione.Approved, Vet Approved, Withdrawn
CefalotinCefalotin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
CefamandoleCefamandole may increase the anticoagulant activities of Fluindione.Approved
CefapirinCefapirin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
CefatrizineCefatrizine may increase the anticoagulant activities of Fluindione.Experimental
CefazedoneCefazedone may increase the anticoagulant activities of Fluindione.Experimental
CefazolinCefazolin may increase the anticoagulant activities of Fluindione.Approved
CefbuperazoneCefbuperazone may increase the anticoagulant activities of Fluindione.Experimental
CefetametCefetamet may increase the anticoagulant activities of Fluindione.Experimental
CefiximeCefixime may increase the anticoagulant activities of Fluindione.Approved
CefmenoximeCefmenoxime may increase the anticoagulant activities of Fluindione.Approved
CefmetazoleCefmetazole may increase the anticoagulant activities of Fluindione.Approved
CefminoxCefminox may increase the anticoagulant activities of Fluindione.Approved
CefodizimeCefodizime may increase the anticoagulant activities of Fluindione.Experimental
CefonicidCefonicid may increase the anticoagulant activities of Fluindione.Approved
CefoperazoneCefoperazone may increase the anticoagulant activities of Fluindione.Approved
CeforanideCeforanide may increase the anticoagulant activities of Fluindione.Approved
CefotaximeCefotaxime may increase the anticoagulant activities of Fluindione.Approved
CefotetanCefotetan may increase the anticoagulant activities of Fluindione.Approved
CefotiamCefotiam may increase the anticoagulant activities of Fluindione.Approved
CefoxitinCefoxitin may increase the anticoagulant activities of Fluindione.Approved
CefpodoximeCefpodoxime may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
CefradineCefradine may increase the anticoagulant activities of Fluindione.Approved
CefroxadineCefroxadine may increase the anticoagulant activities of Fluindione.Withdrawn
CefsulodinCefsulodin may increase the anticoagulant activities of Fluindione.Experimental
CeftazidimeCeftazidime may increase the anticoagulant activities of Fluindione.Approved
CeftezoleCeftezole may increase the anticoagulant activities of Fluindione.Experimental
CeftizoximeCeftizoxime may increase the anticoagulant activities of Fluindione.Approved
CeftriaxoneCeftriaxone may increase the anticoagulant activities of Fluindione.Approved
CefuroximeCefuroxime may increase the anticoagulant activities of Fluindione.Approved
CelecoxibCelecoxib may increase the anticoagulant activities of Fluindione.Approved, Investigational
CephalexinCephalexin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
CephaloglycinCephaloglycin may increase the anticoagulant activities of Fluindione.Approved
CephaloridineCephaloridine may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
CerivastatinCerivastatin may increase the anticoagulant activities of Fluindione.Withdrawn
CertoparinCertoparin may increase the anticoagulant activities of Fluindione.Approved
Chloral hydrateThe serum concentration of Fluindione can be increased when it is combined with Chloral hydrate.Approved, Illicit, Vet Approved
ChloramphenicolChloramphenicol may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
ChloroquineChloroquine may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
ChlorotrianiseneChlorotrianisene may decrease the anticoagulant activities of Fluindione.Withdrawn
ChlorpropamideChlorpropamide may increase the anticoagulant activities of Fluindione.Approved
ChlortetracyclineChlortetracycline may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
CholestyramineCholestyramine can cause a decrease in the absorption of Fluindione resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Choline magnesium trisalicylateCholine magnesium trisalicylate may increase the anticoagulant activities of Fluindione.Approved
CilostazolCilostazol may increase the anticoagulant activities of Fluindione.Approved
CimetidineCimetidine may increase the anticoagulant activities of Fluindione.Approved
CinoxacinCinoxacin may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
CiprofibrateCiprofibrate may increase the anticoagulant activities of Fluindione.Approved
CitalopramCitalopram may increase the anticoagulant activities of Fluindione.Approved
Citric AcidCitric Acid may increase the anticoagulant activities of Fluindione.Nutraceutical, Vet Approved
ClarithromycinThe serum concentration of Fluindione can be increased when it is combined with Clarithromycin.Approved
ClofibrateClofibrate may increase the anticoagulant activities of Fluindione.Approved
ClofibrideClofibride may increase the anticoagulant activities of Fluindione.Experimental
ClomipramineClomipramine may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
ClonixinClonixin may increase the anticoagulant activities of Fluindione.Approved
ClopidogrelClopidogrel may increase the anticoagulant activities of Fluindione.Approved, Nutraceutical
CloricromenCloricromen may increase the anticoagulant activities of Fluindione.Experimental
ClorindioneClorindione may increase the anticoagulant activities of Fluindione.Experimental
CloxacillinCloxacillin may decrease the anticoagulant activities of Fluindione.Approved, Vet Approved
ColesevelamColesevelam can cause a decrease in the absorption of Fluindione resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
ColestipolColestipol can cause a decrease in the absorption of Fluindione resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
Collagenase clostridium histolyticumThe risk or severity of adverse effects can be increased when Fluindione is combined with Collagenase clostridium histolyticum.Approved, Investigational
Conjugated estrogensConjugated estrogens may decrease the anticoagulant activities of Fluindione.Approved
CranberryCranberry may increase the anticoagulant activities of Fluindione.Approved
CurcuminCurcumin may increase the anticoagulant activities of Fluindione.Investigational
CyclacillinCyclacillin may increase the anticoagulant activities of Fluindione.Approved
CyclobenzaprineCyclobenzaprine may increase the anticoagulant activities of Fluindione.Approved
D-LimoneneD-Limonene may increase the anticoagulant activities of Fluindione.Investigational
DaidzeinDaidzein may decrease the anticoagulant activities of Fluindione.Experimental
DalteparinDalteparin may increase the anticoagulant activities of Fluindione.Approved
DanaparoidDanaparoid may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
DapoxetineDapoxetine may increase the anticoagulant activities of Fluindione.Investigational
DarexabanDarexaban may increase the anticoagulant activities of Fluindione.Investigational
DasatinibDasatinib may increase the anticoagulant activities of Fluindione.Approved, Investigational
DeferasiroxThe risk or severity of adverse effects can be increased when Fluindione is combined with Deferasirox.Approved, Investigational
DefibrotideDefibrotide may increase the anticoagulant activities of Fluindione.Approved, Investigational
DemeclocyclineDemeclocycline may increase the anticoagulant activities of Fluindione.Approved
DemegestoneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Demegestone.Experimental
Deoxycholic AcidThe risk or severity of adverse effects can be increased when Fluindione is combined with Deoxycholic Acid.Approved
dersalazinedersalazine may increase the anticoagulant activities of Fluindione.Investigational
DesipramineDesipramine may increase the anticoagulant activities of Fluindione.Approved
DesirudinDesirudin may increase the anticoagulant activities of Fluindione.Approved
DesmoteplaseDesmoteplase may increase the anticoagulant activities of Fluindione.Investigational
DesogestrelDesogestrel may decrease the anticoagulant activities of Fluindione.Approved
DesvenlafaxineThe risk or severity of adverse effects can be increased when Desvenlafaxine is combined with Fluindione.Approved
DexmethylphenidateThe serum concentration of Fluindione can be increased when it is combined with Dexmethylphenidate.Approved
DextranDextran may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
Dextran 40Dextran 40 may increase the anticoagulant activities of Fluindione.Approved
Dextran 70Dextran 70 may increase the anticoagulant activities of Fluindione.Approved
Dextran 75Dextran 75 may increase the anticoagulant activities of Fluindione.Approved
DibenzepinDibenzepin may increase the anticoagulant activities of Fluindione.Experimental
DiclofenacDiclofenac may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
DicloxacillinDicloxacillin may decrease the anticoagulant activities of Fluindione.Approved, Vet Approved
DicoumarolDicoumarol may increase the anticoagulant activities of Fluindione.Approved
DienestrolDienestrol may decrease the anticoagulant activities of Fluindione.Approved
DienogestDienogest may decrease the anticoagulant activities of Fluindione.Approved
DiethylstilbestrolDiethylstilbestrol may decrease the anticoagulant activities of Fluindione.Approved
DifenpiramideDifenpiramide may increase the anticoagulant activities of Fluindione.Experimental
DiflunisalDiflunisal may increase the anticoagulant activities of Fluindione.Approved
DihydrotestosteroneDihydrotestosterone may increase the anticoagulant activities of Fluindione.Illicit
DiphenadioneDiphenadione may increase the anticoagulant activities of Fluindione.Experimental
DipyridamoleDipyridamole may increase the anticoagulant activities of Fluindione.Approved
DisulfiramThe serum concentration of Fluindione can be increased when it is combined with Disulfiram.Approved
DitazoleDitazole may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
DosulepinDosulepin may increase the anticoagulant activities of Fluindione.Approved
DoxepinDoxepin may increase the anticoagulant activities of Fluindione.Approved
DoxycyclineDoxycycline may increase the anticoagulant activities of Fluindione.Approved, Investigational, Vet Approved
DronedaroneThe serum concentration of Fluindione can be increased when it is combined with Dronedarone.Approved
DrospirenoneDrospirenone may decrease the anticoagulant activities of Fluindione.Approved
Drotrecogin alfaDrotrecogin alfa may increase the anticoagulant activities of Fluindione.Approved, Investigational, Withdrawn
DroxicamDroxicam may increase the anticoagulant activities of Fluindione.Approved
DuloxetineDuloxetine may increase the anticoagulant activities of Fluindione.Approved
DuvelisibDuvelisib may increase the anticoagulant activities of Fluindione.Investigational
DydrogesteroneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Dydrogesterone.Approved, Withdrawn
E-6201E-6201 may increase the anticoagulant activities of Fluindione.Investigational
EconazoleThe serum concentration of Fluindione can be increased when it is combined with Econazole.Approved
Edetic AcidEdetic Acid may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
EdoxabanEdoxaban may increase the anticoagulant activities of Fluindione.Approved
EfavirenzThe serum concentration of Fluindione can be decreased when it is combined with Efavirenz.Approved, Investigational
EnoxacinEnoxacin may increase the anticoagulant activities of Fluindione.Approved
EnoxaparinEnoxaparin may increase the anticoagulant activities of Fluindione.Approved
EpicillinEpicillin may increase the anticoagulant activities of Fluindione.Experimental
EpimestrolEpimestrol may decrease the anticoagulant activities of Fluindione.Experimental
EpinastineEpinastine may increase the anticoagulant activities of Fluindione.Approved, Investigational
EpirizoleEpirizole may increase the anticoagulant activities of Fluindione.Approved
EplivanserinEplivanserin may increase the anticoagulant activities of Fluindione.Investigational
eplivanserineeplivanserine may increase the anticoagulant activities of Fluindione.Investigational
EpoprostenolEpoprostenol may increase the anticoagulant activities of Fluindione.Approved
EptifibatideEptifibatide may increase the anticoagulant activities of Fluindione.Approved, Investigational
EquolEquol may decrease the anticoagulant activities of Fluindione.Investigational
EscitalopramEscitalopram may increase the anticoagulant activities of Fluindione.Approved, Investigational
EsmirtazapineEsmirtazapine may increase the anticoagulant activities of Fluindione.Investigational
EsomeprazoleThe serum concentration of Fluindione can be increased when it is combined with Esomeprazole.Approved, Investigational
EstradiolEstradiol may decrease the anticoagulant activities of Fluindione.Approved, Investigational, Vet Approved
EstramustineEstramustine may decrease the anticoagulant activities of Fluindione.Approved
EstriolEstriol may decrease the anticoagulant activities of Fluindione.Approved, Vet Approved
Estrogens, esterifiedEstrogens, esterified may decrease the anticoagulant activities of Fluindione.Approved
EstroneEstrone may decrease the anticoagulant activities of Fluindione.Approved
Estrone sulfateEstrone sulfate may decrease the anticoagulant activities of Fluindione.Approved
Etacrynic acidThe serum concentration of Fluindione can be increased when it is combined with Etacrynic acid.Approved
EtanerceptEtanercept may increase the anticoagulant activities of Fluindione.Approved, Investigational
EthanolThe serum concentration of Fluindione can be decreased when it is combined with Ethanol.Approved
EthenzamideEthenzamide may increase the anticoagulant activities of Fluindione.Experimental
Ethinyl EstradiolEthinyl Estradiol may decrease the anticoagulant activities of Fluindione.Approved
EthotoinEthotoin may increase the anticoagulant activities of Fluindione.Approved
Ethyl biscoumacetateEthyl biscoumacetate may increase the anticoagulant activities of Fluindione.Withdrawn
Ethynodiol diacetateEthynodiol diacetate may decrease the anticoagulant activities of Fluindione.Approved
EtodolacEtodolac may increase the anticoagulant activities of Fluindione.Approved, Investigational, Vet Approved
EtofenamateEtofenamate may increase the anticoagulant activities of Fluindione.Approved
EtofibrateEtofibrate may increase the anticoagulant activities of Fluindione.Approved
EtonogestrelEtonogestrel may decrease the anticoagulant activities of Fluindione.Approved, Investigational
EtoperidoneEtoperidone may increase the anticoagulant activities of Fluindione.Approved
EtoposideEtoposide may increase the anticoagulant activities of Fluindione.Approved
EtoricoxibEtoricoxib may increase the anticoagulant activities of Fluindione.Approved, Investigational
Evening primrose oilEvening primrose oil may increase the anticoagulant activities of Fluindione.Approved
ExenatideExenatide may increase the anticoagulant activities of Fluindione.Approved, Investigational
exisulindexisulind may increase the anticoagulant activities of Fluindione.Investigational
FelbinacFelbinac may increase the anticoagulant activities of Fluindione.Experimental
FenbufenFenbufen may increase the anticoagulant activities of Fluindione.Approved
FenofibrateFenofibrate may increase the anticoagulant activities of Fluindione.Approved
Fenofibric acidFenofibric acid may increase the anticoagulant activities of Fluindione.Approved
FenoprofenFenoprofen may increase the anticoagulant activities of Fluindione.Approved
FentiazacFentiazac may increase the anticoagulant activities of Fluindione.Experimental
FeprazoneFeprazone may increase the anticoagulant activities of Fluindione.Experimental
Ferulic acidFerulic acid may increase the anticoagulant activities of Fluindione.Experimental
FibrinolysinFibrinolysin may increase the anticoagulant activities of Fluindione.Investigational
FleroxacinFleroxacin may increase the anticoagulant activities of Fluindione.Approved
FloctafenineFloctafenine may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
FlucloxacillinFlucloxacillin may decrease the anticoagulant activities of Fluindione.Approved
FluconazoleThe serum concentration of Fluindione can be increased when it is combined with Fluconazole.Approved
FlumequineFlumequine may increase the anticoagulant activities of Fluindione.Withdrawn
FlunixinFlunixin may increase the anticoagulant activities of Fluindione.Vet Approved
FlunoxaprofenFlunoxaprofen may increase the anticoagulant activities of Fluindione.Experimental
FluorouracilThe serum concentration of Fluindione can be increased when it is combined with Fluorouracil.Approved
FluoxetineFluoxetine may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
FluoxymesteroneFluoxymesterone may increase the anticoagulant activities of Fluindione.Approved, Illicit
FlurbiprofenFlurbiprofen may increase the anticoagulant activities of Fluindione.Approved, Investigational
FluvastatinFluvastatin may increase the anticoagulant activities of Fluindione.Approved
FluvoxamineFluvoxamine may increase the anticoagulant activities of Fluindione.Approved, Investigational
FondaparinuxFondaparinux may increase the anticoagulant activities of Fluindione.Investigational
Fondaparinux sodiumFondaparinux sodium may increase the anticoagulant activities of Fluindione.Approved, Investigational
FosphenytoinFosphenytoin may increase the anticoagulant activities of Fluindione.Approved
Fusidic AcidThe serum concentration of Fluindione can be increased when it is combined with Fusidic Acid.Approved
GabexateGabexate may increase the anticoagulant activities of Fluindione.Investigational
GarenoxacinGarenoxacin may increase the anticoagulant activities of Fluindione.Investigational
GatifloxacinGatifloxacin may increase the anticoagulant activities of Fluindione.Approved, Investigational
GefitinibGefitinib may increase the anticoagulant activities of Fluindione.Approved, Investigational
GemfibrozilGemfibrozil may increase the anticoagulant activities of Fluindione.Approved
GemifloxacinGemifloxacin may increase the anticoagulant activities of Fluindione.Approved, Investigational
GenisteinGenistein may decrease the anticoagulant activities of Fluindione.Investigational
GestodeneGestodene may decrease the anticoagulant activities of Fluindione.Approved
GestonoroneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Gestonorone.Experimental
GestrinoneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Gestrinone.Approved
Ginkgo bilobaThe risk or severity of adverse effects can be increased when Ginkgo biloba is combined with Fluindione.Approved, Nutraceutical
GlibornurideGlibornuride may increase the anticoagulant activities of Fluindione.Withdrawn
GliclazideGliclazide may increase the anticoagulant activities of Fluindione.Approved
GlipizideGlipizide may increase the anticoagulant activities of Fluindione.Approved
GliquidoneGliquidone may increase the anticoagulant activities of Fluindione.Approved
GlisoxepideGlisoxepide may increase the anticoagulant activities of Fluindione.Approved
GLPG-0492GLPG-0492 may increase the anticoagulant activities of Fluindione.Investigational
Glucagon recombinantGlucagon recombinant may increase the anticoagulant activities of Fluindione.Approved
GlutethimideThe metabolism of Fluindione can be increased when combined with Glutethimide.Approved, Illicit
GlyburideGlyburide may increase the anticoagulant activities of Fluindione.Approved
GrepafloxacinGrepafloxacin may increase the anticoagulant activities of Fluindione.Withdrawn
GriseofulvinThe serum concentration of Fluindione can be decreased when it is combined with Griseofulvin.Approved, Vet Approved
GuacetisalGuacetisal may increase the anticoagulant activities of Fluindione.Experimental
HeminHemin may increase the anticoagulant activities of Fluindione.Approved
Hemoglobin crosfumarilHemoglobin crosfumaril may increase the anticoagulant activities of Fluindione.Experimental
HeparinHeparin may increase the anticoagulant activities of Fluindione.Approved, Investigational
HexestrolHexestrol may decrease the anticoagulant activities of Fluindione.Withdrawn
HexobarbitalThe metabolism of Fluindione can be increased when combined with Hexobarbital.Approved
HigenamineHigenamine may increase the anticoagulant activities of Fluindione.Investigational
Hydroxyprogesterone caproateThe therapeutic efficacy of Fluindione can be decreased when used in combination with Hydroxyprogesterone caproate.Approved
HydroxytyrosolHydroxytyrosol may increase the anticoagulant activities of Fluindione.Investigational
Ibritumomab tiuxetanThe risk or severity of adverse effects can be increased when Fluindione is combined with Ibritumomab tiuxetan.Approved
IbrutinibThe risk or severity of adverse effects can be increased when Ibrutinib is combined with Fluindione.Approved
IbudilastIbudilast may increase the anticoagulant activities of Fluindione.Approved, Investigational
IbuprofenIbuprofen may increase the anticoagulant activities of Fluindione.Approved
IbuproxamIbuproxam may increase the anticoagulant activities of Fluindione.Withdrawn
IcatibantIcatibant may increase the anticoagulant activities of Fluindione.Approved
Icosapent ethylIcosapent ethyl may increase the anticoagulant activities of Fluindione.Approved, Nutraceutical
IdraparinuxIdraparinux may increase the anticoagulant activities of Fluindione.Investigational
IfenprodilIfenprodil may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
IfetrobanIfetroban may increase the anticoagulant activities of Fluindione.Investigational
IfosfamideIfosfamide may increase the anticoagulant activities of Fluindione.Approved
IloprostIloprost may increase the anticoagulant activities of Fluindione.Approved, Investigational
Imidazole salicylateImidazole salicylate may increase the anticoagulant activities of Fluindione.Experimental
ImipramineImipramine may increase the anticoagulant activities of Fluindione.Approved
IndalpineIndalpine may increase the anticoagulant activities of Fluindione.Investigational, Withdrawn
IndobufenIndobufen may increase the anticoagulant activities of Fluindione.Investigational
IndomethacinIndomethacin may increase the anticoagulant activities of Fluindione.Approved, Investigational
IndoprofenIndoprofen may increase the anticoagulant activities of Fluindione.Withdrawn
IprindoleIprindole may increase the anticoagulant activities of Fluindione.Experimental
IsoxicamIsoxicam may increase the anticoagulant activities of Fluindione.Withdrawn
ItraconazoleThe serum concentration of Fluindione can be increased when it is combined with Itraconazole.Approved, Investigational
IvermectinIvermectin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
JosamycinThe serum concentration of Fluindione can be increased when it is combined with Josamycin.Approved
KebuzoneKebuzone may increase the anticoagulant activities of Fluindione.Experimental
KetanserinKetanserin may increase the anticoagulant activities of Fluindione.Investigational
KetoconazoleThe serum concentration of Fluindione can be increased when it is combined with Ketoconazole.Approved, Investigational
KetoprofenKetoprofen may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
KetorolacKetorolac may increase the anticoagulant activities of Fluindione.Approved
KitasamycinThe serum concentration of Fluindione can be increased when it is combined with Kitasamycin.Experimental
L-CarnitineL-Carnitine may increase the anticoagulant activities of Fluindione.Approved
LansoprazoleThe serum concentration of Fluindione can be increased when it is combined with Lansoprazole.Approved, Investigational
LeflunomideLeflunomide may increase the anticoagulant activities of Fluindione.Approved, Investigational
LepirudinLepirudin may increase the anticoagulant activities of Fluindione.Approved
LetaxabanLetaxaban may increase the anticoagulant activities of Fluindione.Investigational
LevofloxacinLevofloxacin may increase the anticoagulant activities of Fluindione.Approved, Investigational
LevomilnacipranThe risk or severity of adverse effects can be increased when Levomilnacipran is combined with Fluindione.Approved
LevonorgestrelLevonorgestrel may decrease the anticoagulant activities of Fluindione.Approved, Investigational
LevothyroxineLevothyroxine may increase the anticoagulant activities of Fluindione.Approved
LimaprostThe risk or severity of adverse effects can be increased when Limaprost is combined with Fluindione.Approved
LinsidomineLinsidomine may increase the anticoagulant activities of Fluindione.Experimental
LiothyronineLiothyronine may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
LiotrixLiotrix may increase the anticoagulant activities of Fluindione.Approved
LisofyllineLisofylline may increase the anticoagulant activities of Fluindione.Investigational
LixisenatideLixisenatide can cause a decrease in the absorption of Fluindione resulting in a reduced serum concentration and potentially a decrease in efficacy.Approved
LofepramineLofepramine may increase the anticoagulant activities of Fluindione.Experimental
LonazolacLonazolac may increase the anticoagulant activities of Fluindione.Experimental
LornoxicamLornoxicam may increase the anticoagulant activities of Fluindione.Approved
LovastatinLovastatin may increase the anticoagulant activities of Fluindione.Approved, Investigational
LoxoprofenLoxoprofen may increase the anticoagulant activities of Fluindione.Approved
LumiracoxibLumiracoxib may increase the anticoagulant activities of Fluindione.Approved, Investigational
LynestrenolLynestrenol may decrease the anticoagulant activities of Fluindione.Investigational
Magnesium salicylateMagnesium salicylate may increase the anticoagulant activities of Fluindione.Approved
MasoprocolMasoprocol may increase the anticoagulant activities of Fluindione.Approved
Meclofenamic acidMeclofenamic acid may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
MedrogestoneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Medrogestone.Approved
Medroxyprogesterone acetateMedroxyprogesterone acetate may decrease the anticoagulant activities of Fluindione.Approved, Investigational
Mefenamic acidMefenamic acid may increase the anticoagulant activities of Fluindione.Approved
MelagatranFluindione may increase the anticoagulant activities of Melagatran.Experimental
MeloxicamMeloxicam may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
MercaptopurineMercaptopurine may decrease the anticoagulant activities of Fluindione.Approved
MesalazineMesalazine may increase the anticoagulant activities of Fluindione.Approved
MesteroloneMesterolone may increase the anticoagulant activities of Fluindione.Experimental
MestranolMestranol may decrease the anticoagulant activities of Fluindione.Approved
MetahexamideMetahexamide may increase the anticoagulant activities of Fluindione.Experimental
MetamizoleMetamizole may increase the anticoagulant activities of Fluindione.Withdrawn
MetampicillinMetampicillin may increase the anticoagulant activities of Fluindione.Experimental
MethallenestrilMethallenestril may decrease the anticoagulant activities of Fluindione.Experimental
MethimazoleMethimazole may decrease the anticoagulant activities of Fluindione.Approved
MethohexitalThe metabolism of Fluindione can be increased when combined with Methohexital.Approved
MethylestrenoloneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Methylestrenolone.Experimental
MethylphenidateThe serum concentration of Fluindione can be increased when it is combined with Methylphenidate.Approved, Investigational
MethylphenobarbitalThe metabolism of Fluindione can be increased when combined with Methylphenobarbital.Approved
MethyltestosteroneMethyltestosterone may increase the anticoagulant activities of Fluindione.Approved
MethylthiouracilMethylthiouracil may decrease the anticoagulant activities of Fluindione.Experimental
MeticillinMeticillin may increase the anticoagulant activities of Fluindione.Approved
MetronidazoleThe serum concentration of Fluindione can be increased when it is combined with Metronidazole.Approved
MevastatinMevastatin may increase the anticoagulant activities of Fluindione.Experimental
MezlocillinMezlocillin may increase the anticoagulant activities of Fluindione.Approved
MiconazoleThe serum concentration of Fluindione can be increased when it is combined with Miconazole.Approved, Investigational, Vet Approved
MilnacipranThe risk or severity of adverse effects can be increased when Milnacipran is combined with Fluindione.Approved
MilrinoneMilrinone may increase the anticoagulant activities of Fluindione.Approved
MinocyclineMinocycline may increase the anticoagulant activities of Fluindione.Approved, Investigational
MirtazapineMirtazapine may increase the anticoagulant activities of Fluindione.Approved
MizoribineMizoribine may increase the anticoagulant activities of Fluindione.Investigational
MofebutazoneMofebutazone may increase the anticoagulant activities of Fluindione.Experimental
MoxestrolMoxestrol may decrease the anticoagulant activities of Fluindione.Experimental
Mycophenolate mofetilMycophenolate mofetil may increase the anticoagulant activities of Fluindione.Approved, Investigational
Mycophenolic acidMycophenolic acid may increase the anticoagulant activities of Fluindione.Approved
NabumetoneNabumetone may increase the anticoagulant activities of Fluindione.Approved
NadroparinNadroparin may increase the anticoagulant activities of Fluindione.Approved
NafamostatNafamostat may increase the anticoagulant activities of Fluindione.Approved, Investigational
NafcillinNafcillin may decrease the anticoagulant activities of Fluindione.Approved
NaftifineNaftifine may increase the anticoagulant activities of Fluindione.Approved
NaftopidilNaftopidil may increase the anticoagulant activities of Fluindione.Investigational
Nalidixic AcidNalidixic Acid may increase the anticoagulant activities of Fluindione.Approved
NandroloneNandrolone may increase the anticoagulant activities of Fluindione.Experimental
NaproxenNaproxen may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
NefazodoneNefazodone may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
NemonoxacinNemonoxacin may increase the anticoagulant activities of Fluindione.Investigational
NeomycinNeomycin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
NepafenacNepafenac may increase the anticoagulant activities of Fluindione.Approved
NifenazoneNifenazone may increase the anticoagulant activities of Fluindione.Experimental
Niflumic AcidNiflumic Acid may increase the anticoagulant activities of Fluindione.Approved
NimesulideNimesulide may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
NintedanibThe risk or severity of adverse effects can be increased when Fluindione is combined with Nintedanib.Approved
NitroaspirinNitroaspirin may increase the anticoagulant activities of Fluindione.Investigational
NomegestrolThe therapeutic efficacy of Fluindione can be decreased when used in combination with Nomegestrol.Approved
NorelgestrominNorelgestromin may decrease the anticoagulant activities of Fluindione.Approved
NorethisteroneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Norethisterone.Approved
NorfloxacinNorfloxacin may increase the anticoagulant activities of Fluindione.Approved
NorgestimateNorgestimate may decrease the anticoagulant activities of Fluindione.Approved
NorgestrelNorgestrel may decrease the anticoagulant activities of Fluindione.Approved
NorgestrienoneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Norgestrienone.Experimental
NortriptylineNortriptyline may increase the anticoagulant activities of Fluindione.Approved
ObinutuzumabThe risk or severity of adverse effects can be increased when Fluindione is combined with Obinutuzumab.Approved
OleandomycinThe serum concentration of Fluindione can be increased when it is combined with Oleandomycin.Vet Approved
OlopatadineOlopatadine may increase the anticoagulant activities of Fluindione.Approved
OlsalazineOlsalazine may increase the anticoagulant activities of Fluindione.Approved
Omacetaxine mepesuccinateThe risk or severity of adverse effects can be increased when Fluindione is combined with Omacetaxine mepesuccinate.Approved
Omega-3 fatty acidsOmega-3 fatty acids may increase the anticoagulant activities of Fluindione.Approved, Nutraceutical
OmeprazoleThe serum concentration of Fluindione can be increased when it is combined with Omeprazole.Approved, Investigational, Vet Approved
OpipramolOpipramol may increase the anticoagulant activities of Fluindione.Investigational
OrgoteinOrgotein may increase the anticoagulant activities of Fluindione.Vet Approved
OritavancinThe serum concentration of Fluindione can be increased when it is combined with Oritavancin.Approved, Investigational
OtamixabanOtamixaban may increase the anticoagulant activities of Fluindione.Investigational
OxacillinOxacillin may increase the anticoagulant activities of Fluindione.Approved
OxandroloneOxandrolone may increase the anticoagulant activities of Fluindione.Approved, Investigational
OxaprozinOxaprozin may increase the anticoagulant activities of Fluindione.Approved
Oxolinic acidOxolinic acid may increase the anticoagulant activities of Fluindione.Experimental
OxymetholoneOxymetholone may increase the anticoagulant activities of Fluindione.Approved, Illicit
OxyphenbutazoneOxyphenbutazone may increase the anticoagulant activities of Fluindione.Withdrawn
OzagrelOzagrel may increase the anticoagulant activities of Fluindione.Investigational
ParecoxibParecoxib may increase the anticoagulant activities of Fluindione.Approved
ParnaparinParnaparin may increase the anticoagulant activities of Fluindione.Approved
ParoxetineParoxetine may increase the anticoagulant activities of Fluindione.Approved, Investigational
ParthenolideParthenolide may increase the anticoagulant activities of Fluindione.Investigational
PazufloxacinPazufloxacin may increase the anticoagulant activities of Fluindione.Investigational
PefloxacinPefloxacin may increase the anticoagulant activities of Fluindione.Approved
PenamecillinPenamecillin may increase the anticoagulant activities of Fluindione.Experimental
PenimepicyclinePenimepicycline may increase the anticoagulant activities of Fluindione.Experimental
PentobarbitalThe metabolism of Fluindione can be increased when combined with Pentobarbital.Approved, Vet Approved
Pentosan PolysulfatePentosan Polysulfate may increase the anticoagulant activities of Fluindione.Approved
PentoxifyllinePentoxifylline may increase the anticoagulant activities of Fluindione.Approved, Investigational
PhenindionePhenindione may increase the anticoagulant activities of Fluindione.Approved
PhenobarbitalThe metabolism of Fluindione can be increased when combined with Phenobarbital.Approved
PhenoxymethylpenicillinPhenoxymethylpenicillin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
PhenprocoumonPhenprocoumon may increase the anticoagulant activities of Fluindione.Approved
PhenylbutazonePhenylbutazone may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
PhenytoinPhenytoin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
PhylloquinonePhylloquinone may decrease the anticoagulant activities of Fluindione.Approved
PicotamidePicotamide may increase the anticoagulant activities of Fluindione.Experimental
PimecrolimusPimecrolimus may increase the anticoagulant activities of Fluindione.Approved, Investigational
Pipemidic acidPipemidic acid may increase the anticoagulant activities of Fluindione.Experimental
PiperacillinPiperacillin may increase the anticoagulant activities of Fluindione.Approved
PirfenidonePirfenidone may increase the anticoagulant activities of Fluindione.Investigational
Piromidic acidPiromidic acid may increase the anticoagulant activities of Fluindione.Experimental
PiroxicamPiroxicam may increase the anticoagulant activities of Fluindione.Approved, Investigational
PirprofenPirprofen may increase the anticoagulant activities of Fluindione.Experimental
PitavastatinPitavastatin may increase the anticoagulant activities of Fluindione.Approved
PivampicillinPivampicillin may increase the anticoagulant activities of Fluindione.Approved
PivmecillinamPivmecillinam may increase the anticoagulant activities of Fluindione.Approved
Polyestradiol phosphatePolyestradiol phosphate may decrease the anticoagulant activities of Fluindione.Approved
PosaconazoleThe serum concentration of Fluindione can be increased when it is combined with Posaconazole.Approved, Investigational, Vet Approved
PranoprofenPranoprofen may increase the anticoagulant activities of Fluindione.Experimental
PrasugrelPrasugrel may increase the anticoagulant activities of Fluindione.Approved
PravastatinPravastatin may increase the anticoagulant activities of Fluindione.Approved
PrimidoneThe metabolism of Fluindione can be increased when combined with Primidone.Approved, Vet Approved
Procaine benzylpenicillinProcaine benzylpenicillin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
ProgesteroneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Progesterone.Approved, Vet Approved
ProglumetacinProglumetacin may increase the anticoagulant activities of Fluindione.Experimental
PromegestoneThe therapeutic efficacy of Fluindione can be decreased when used in combination with Promegestone.Experimental
PromestrienePromestriene may decrease the anticoagulant activities of Fluindione.Investigational
PropacetamolPropacetamol may increase the anticoagulant activities of Fluindione.Approved
PropafenoneThe serum concentration of Fluindione can be increased when it is combined with Propafenone.Approved
PropicillinPropicillin may increase the anticoagulant activities of Fluindione.Experimental
PropylthiouracilPropylthiouracil may decrease the anticoagulant activities of Fluindione.Approved
PropyphenazonePropyphenazone may increase the anticoagulant activities of Fluindione.Experimental
ProquazoneProquazone may increase the anticoagulant activities of Fluindione.Experimental
Protein CProtein C may increase the anticoagulant activities of Fluindione.Approved
Protein S humanFluindione may increase the anticoagulant activities of Protein S human.Approved
ProtocatechualdehydeProtocatechualdehyde may increase the anticoagulant activities of Fluindione.Approved
ProtriptylineProtriptyline may increase the anticoagulant activities of Fluindione.Approved
PrulifloxacinPrulifloxacin may increase the anticoagulant activities of Fluindione.Investigational
PTC299PTC299 may increase the anticoagulant activities of Fluindione.Investigational
QuinestrolQuinestrol may decrease the anticoagulant activities of Fluindione.Approved
QuinidineQuinidine may increase the anticoagulant activities of Fluindione.Approved
QuinineQuinine may increase the anticoagulant activities of Fluindione.Approved
RamatrobanRamatroban may increase the anticoagulant activities of Fluindione.Investigational
ResveratrolResveratrol may increase the anticoagulant activities of Fluindione.Experimental, Investigational
ReteplaseReteplase may increase the anticoagulant activities of Fluindione.Approved
ReviparinReviparin may increase the anticoagulant activities of Fluindione.Approved
RidogrelRidogrel may increase the anticoagulant activities of Fluindione.Approved
RifabutinThe metabolism of Fluindione can be increased when combined with Rifabutin.Approved
RifampicinThe metabolism of Fluindione can be increased when combined with Rifampicin.Approved
RifapentineThe metabolism of Fluindione can be increased when combined with Rifapentine.Approved
RivaroxabanFluindione may increase the anticoagulant activities of Rivaroxaban.Approved
RofecoxibRofecoxib may increase the anticoagulant activities of Fluindione.Investigational, Withdrawn
RonifibrateRonifibrate may increase the anticoagulant activities of Fluindione.Experimental
RosiglitazoneRosiglitazone may increase the anticoagulant activities of Fluindione.Approved, Investigational
RosoxacinRosoxacin may increase the anticoagulant activities of Fluindione.Approved
RosuvastatinRosuvastatin may increase the anticoagulant activities of Fluindione.Approved
RufloxacinRufloxacin may increase the anticoagulant activities of Fluindione.Experimental
SalicylamideSalicylamide may increase the anticoagulant activities of Fluindione.Approved
Salicylic acidSalicylic acid may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
SalsalateSalsalate may increase the anticoagulant activities of Fluindione.Approved
SarpogrelateSarpogrelate may increase the anticoagulant activities of Fluindione.Investigational
SaruplaseSaruplase may increase the anticoagulant activities of Fluindione.Experimental
SecobarbitalThe metabolism of Fluindione can be increased when combined with Secobarbital.Approved, Vet Approved
SecoisolariciresinolSecoisolariciresinol may decrease the anticoagulant activities of Fluindione.Investigational
SelexipagSelexipag may increase the anticoagulant activities of Fluindione.Approved
SemapimodSemapimod may increase the anticoagulant activities of Fluindione.Investigational
SeratrodastSeratrodast may increase the anticoagulant activities of Fluindione.Approved
SerrapeptaseSerrapeptase may increase the anticoagulant activities of Fluindione.Investigational
SertralineSertraline may increase the anticoagulant activities of Fluindione.Approved
SevofluraneSevoflurane may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
SimfibrateSimfibrate may increase the anticoagulant activities of Fluindione.Experimental
SimvastatinSimvastatin may increase the anticoagulant activities of Fluindione.Approved
SitafloxacinSitafloxacin may increase the anticoagulant activities of Fluindione.Experimental
SolithromycinThe serum concentration of Fluindione can be increased when it is combined with Solithromycin.Investigational
SparfloxacinSparfloxacin may increase the anticoagulant activities of Fluindione.Approved
SRT501SRT501 may increase the anticoagulant activities of Fluindione.Investigational
St. John's WortThe metabolism of Fluindione can be increased when combined with St. John's Wort.Nutraceutical
StanozololStanozolol may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
StreptokinaseStreptokinase may increase the anticoagulant activities of Fluindione.Approved
SucralfateSucralfate may decrease the anticoagulant activities of Fluindione.Approved
SugammadexSugammadex may increase the anticoagulant activities of Fluindione.Approved
SulbactamSulbactam may increase the anticoagulant activities of Fluindione.Approved
SulbenicillinSulbenicillin may increase the anticoagulant activities of Fluindione.Experimental
SulfadiazineSulfadiazine may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
SulfamethoxazoleSulfamethoxazole may increase the anticoagulant activities of Fluindione.Approved
SulfasalazineSulfasalazine may increase the anticoagulant activities of Fluindione.Approved
SulfinpyrazoneThe metabolism of Fluindione can be decreased when combined with Sulfinpyrazone.Approved
SulfisoxazoleSulfisoxazole may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
SulindacSulindac may increase the anticoagulant activities of Fluindione.Approved
SulodexideSulodexide may increase the anticoagulant activities of Fluindione.Approved, Investigational
SultamicillinSultamicillin may increase the anticoagulant activities of Fluindione.Investigational
SuprofenSuprofen may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
SuxibuzoneSuxibuzone may increase the anticoagulant activities of Fluindione.Experimental
Synthetic Conjugated Estrogens, ASynthetic Conjugated Estrogens, A may decrease the anticoagulant activities of Fluindione.Approved
Synthetic Conjugated Estrogens, BSynthetic Conjugated Estrogens, B may decrease the anticoagulant activities of Fluindione.Approved
TalampicillinTalampicillin may increase the anticoagulant activities of Fluindione.Experimental
TamoxifenThe serum concentration of Fluindione can be increased when it is combined with Tamoxifen.Approved
TarenflurbilTarenflurbil may increase the anticoagulant activities of Fluindione.Investigational
TazobactamTazobactam may increase the anticoagulant activities of Fluindione.Approved
TegafurThe serum concentration of Fluindione can be increased when it is combined with Tegafur.Approved
TelithromycinThe serum concentration of Fluindione can be increased when it is combined with Telithromycin.Approved
TemafloxacinTemafloxacin may increase the anticoagulant activities of Fluindione.Withdrawn
TenecteplaseTenecteplase may increase the anticoagulant activities of Fluindione.Approved
TenidapTenidap may increase the anticoagulant activities of Fluindione.Experimental
TenoxicamTenoxicam may increase the anticoagulant activities of Fluindione.Approved
TepoxalinTepoxalin may increase the anticoagulant activities of Fluindione.Vet Approved
TeriflunomideTeriflunomide may increase the anticoagulant activities of Fluindione.Approved
TesmilifeneTesmilifene may increase the anticoagulant activities of Fluindione.Investigational
TestosteroneTestosterone may increase the anticoagulant activities of Fluindione.Approved, Investigational
ThiamylalThe metabolism of Fluindione can be increased when combined with Thiamylal.Approved, Vet Approved
ThiopentalThe metabolism of Fluindione can be increased when combined with Thiopental.Approved, Vet Approved
Thyroid, porcineThyroid, porcine may increase the anticoagulant activities of Fluindione.Approved
TianeptineTianeptine may increase the anticoagulant activities of Fluindione.Approved
Tiaprofenic acidTiaprofenic acid may increase the anticoagulant activities of Fluindione.Approved
TiboloneTibolone may increase the anticoagulant activities of Fluindione.Approved
TicagrelorTicagrelor may increase the anticoagulant activities of Fluindione.Approved
TicarcillinTicarcillin may increase the anticoagulant activities of Fluindione.Approved, Vet Approved
TiclopidineTiclopidine may increase the anticoagulant activities of Fluindione.Approved
TinoridineTinoridine may increase the anticoagulant activities of Fluindione.Investigational
TinzaparinTinzaparin may increase the anticoagulant activities of Fluindione.Approved
TioclomarolTioclomarol may increase the anticoagulant activities of Fluindione.Experimental
TipranavirTipranavir may increase the anticoagulant activities of Fluindione.Approved, Investigational
TirofibanTirofiban may increase the anticoagulant activities of Fluindione.Approved
TolazamideTolazamide may increase the anticoagulant activities of Fluindione.Approved
Tolfenamic AcidTolfenamic Acid may increase the anticoagulant activities of Fluindione.Approved
TolmetinTolmetin may increase the anticoagulant activities of Fluindione.Approved
ToremifeneToremifene may increase the anticoagulant activities of Fluindione.Approved, Investigational
TositumomabThe risk or severity of adverse effects can be increased when Fluindione is combined with Tositumomab.Approved
TramadolTramadol may increase the anticoagulant activities of Fluindione.Approved, Investigational
TranilastTranilast may increase the anticoagulant activities of Fluindione.Approved, Investigational
TrapidilTrapidil may increase the anticoagulant activities of Fluindione.Approved
TreprostinilTreprostinil may increase the anticoagulant activities of Fluindione.Approved, Investigational
TribenosideTribenoside may increase the anticoagulant activities of Fluindione.Experimental
TriflusalTriflusal may increase the anticoagulant activities of Fluindione.Approved
TrimipramineTrimipramine may increase the anticoagulant activities of Fluindione.Approved
TriptolideTriptolide may increase the anticoagulant activities of Fluindione.Investigational
TrovafloxacinTrovafloxacin may increase the anticoagulant activities of Fluindione.Approved, Withdrawn
TroxerutinTroxerutin may increase the anticoagulant activities of Fluindione.Investigational
TylosinThe serum concentration of Fluindione can be increased when it is combined with Tylosin.Vet Approved
UbidecarenoneUbidecarenone may decrease the anticoagulant activities of Fluindione.Experimental
UrokinaseUrokinase may increase the anticoagulant activities of Fluindione.Approved, Investigational, Withdrawn
ValdecoxibValdecoxib may increase the anticoagulant activities of Fluindione.Investigational, Withdrawn
VenlafaxineThe risk or severity of adverse effects can be increased when Venlafaxine is combined with Fluindione.Approved
Vitamin EVitamin E may increase the anticoagulant activities of Fluindione.Approved, Nutraceutical, Vet Approved
VorapaxarThe risk or severity of adverse effects can be increased when Vorapaxar is combined with Fluindione.Approved
VoriconazoleThe serum concentration of Fluindione can be increased when it is combined with Voriconazole.Approved, Investigational
VorinostatVorinostat may increase the anticoagulant activities of Fluindione.Approved, Investigational
WarfarinWarfarin may increase the anticoagulant activities of Fluindione.Approved
XimelagatranXimelagatran may increase the anticoagulant activities of Fluindione.Approved, Investigational, Withdrawn
ZafirlukastThe serum concentration of Fluindione can be increased when it is combined with Zafirlukast.Approved, Investigational
ZaltoprofenZaltoprofen may increase the anticoagulant activities of Fluindione.Approved
ZeranolZeranol may decrease the anticoagulant activities of Fluindione.Vet Approved
ZileutonZileuton may increase the anticoagulant activities of Fluindione.Approved, Investigational, Withdrawn
ZimelidineZimelidine may increase the anticoagulant activities of Fluindione.Withdrawn
ZomepiracZomepirac may increase the anticoagulant activities of Fluindione.Withdrawn
Food Interactions
Not Available

References

Synthesis Reference
Not Available
General References
Not Available
External Links
ChemSpider
62167
BindingDB
50280156
ChEBI
134975
ChEMBL
CHEMBL24924
ATC Codes
B01AA12 — Fluindione
AHFS Codes
Not Available
PDB Entries
Not Available
FDA label
Not Available
MSDS
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Not Yet RecruitingTreatmentNonvalvular Atrial Fibrillation1
4Active Not RecruitingTreatmentNonvalvular Atrial Fibrillation1
4CompletedTreatmentDisorders, Blood Coagulation1
4RecruitingTreatmentAnticoagulating Treatment on a Duration at Least 12-month-old Superior / Anticoagulation Treatment at Least > or = to 12-month / Permanent Atrial Fibrillation / Prophylaxis of Pulmonary embolism / Thrombosis, Venous1
Not AvailableNot Yet RecruitingNot AvailablePulmonary Arterial Hypertension (PAH)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0549 mg/mLALOGPS
logP3.09ALOGPS
logP3.02ChemAxon
logS-3.6ALOGPS
pKa (Strongest Acidic)4.19ChemAxon
pKa (Strongest Basic)-7.5ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area34.14 Å2ChemAxon
Rotatable Bond Count1ChemAxon
Refractivity65.45 m3·mol-1ChemAxon
Polarizability23.35 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as indanediones. These are compounds containing an indane ring bearing two ketone groups.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Indanes
Sub Class
Indanones
Direct Parent
Indanediones
Alternative Parents
Aryl alkyl ketones / Fluorobenzenes / Beta-diketones / Aryl fluorides / Organofluorides / Organic oxides / Hydrocarbon derivatives / Aldehydes
Substituents
Indanedione / Aryl alkyl ketone / Aryl ketone / Fluorobenzene / Halobenzene / 1,3-diketone / Aryl fluoride / Aryl halide / Monocyclic benzene moiety / 1,3-dicarbonyl compound
Molecular Framework
Aromatic homopolycyclic compounds
External Descriptors
Not Available

Drug created on October 20, 2016 21:35 / Updated on September 01, 2017 12:28