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IdentificationPharmacologyInteractionsReferencesTrialsEconomicsPropertiesSpectraTaxonomyFluindione
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Name
- Fluindione
- Accession Number
- DB13136
- Type
- Small Molecule
- Groups
- Approved, Investigational
- Description
Fluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior. Fluindione has been investigated for the treatment of Blood Coagulation Disorders.
- Structure
Structure for DB13136 (Fluindione)
- Synonyms
- Not Available
- Categories
- UNII
- EQ35YMS20Q
- CAS number
- 957-56-2
- Weight
- Average: 240.233
Monoisotopic: 240.058657693 - Chemical Formula
- C15H9FO2
- InChI Key
- NASXCEITKQITLD-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H9FO2/c16-10-7-5-9(6-8-10)13-14(17)11-3-1-2-4-12(11)15(13)18/h1-8,13H
- IUPAC Name
- 2-(4-fluorophenyl)-2,3-dihydro-1H-indene-1,3-dione
- SMILES
- FC1=CC=C(C=C1)C1C(=O)C2=CC=CC=C2C1=O
Pharmacology
- Indication
- Not Available
- Structured Indications
- Not Available
- Pharmacodynamics
- Not Available
- Mechanism of action
- Not Available
- Absorption
- Not Available
- Volume of distribution
- Not Available
- Protein binding
- Not Available
- Metabolism
- Not Available
- Route of elimination
- Not Available
- Half life
- Not Available
- Clearance
- Not Available
- Toxicity
- Not Available
- Affected organisms
- Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
Drug Interaction Drug group (4R)-limonene (4R)-limonene may increase the anticoagulant activities of Fluindione. Investigational Abciximab Abciximab may increase the anticoagulant activities of Fluindione. Approved Aceclofenac Aceclofenac may increase the anticoagulant activities of Fluindione. Approved, Investigational Acemetacin The risk or severity of bleeding can be increased when Fluindione is combined with Acemetacin. Approved, Experimental, Investigational Acenocoumarol Acenocoumarol may increase the anticoagulant activities of Fluindione. Approved, Investigational Acetaminophen Acetaminophen may increase the anticoagulant activities of Fluindione. Approved Acetohexamide Acetohexamide may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Acetylsalicylic acid Acetylsalicylic acid may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Adapalene Adapalene may increase the anticoagulant activities of Fluindione. Approved Alaproclate Alaproclate may increase the anticoagulant activities of Fluindione. Experimental Alclofenac Alclofenac may increase the anticoagulant activities of Fluindione. Approved, Withdrawn Allopurinol Allopurinol may increase the anticoagulant activities of Fluindione. Approved Allylestrenol The therapeutic efficacy of Fluindione can be decreased when used in combination with Allylestrenol. Approved Alminoprofen Alminoprofen may increase the anticoagulant activities of Fluindione. Experimental Aloxiprin Aloxiprin may increase the anticoagulant activities of Fluindione. Experimental Alprostadil Alprostadil may increase the anticoagulant activities of Fluindione. Approved, Investigational Alteplase Alteplase may increase the anticoagulant activities of Fluindione. Approved Altrenogest The therapeutic efficacy of Fluindione can be decreased when used in combination with Altrenogest. Vet Approved Aluminium clofibrate Aluminium clofibrate may increase the anticoagulant activities of Fluindione. Experimental Amdinocillin Amdinocillin may increase the anticoagulant activities of Fluindione. Investigational, Withdrawn Amineptine Amineptine may increase the anticoagulant activities of Fluindione. Illicit, Withdrawn Aminosalicylic Acid Aminosalicylic Acid may increase the anticoagulant activities of Fluindione. Approved Amiodarone The therapeutic efficacy of Fluindione can be increased when used in combination with Amiodarone. Approved, Investigational Amitriptyline Amitriptyline may increase the anticoagulant activities of Fluindione. Approved Amitriptylinoxide Amitriptylinoxide may increase the anticoagulant activities of Fluindione. Approved, Investigational Amobarbital The metabolism of Fluindione can be increased when combined with Amobarbital. Approved, Illicit Amoxapine Amoxapine may increase the anticoagulant activities of Fluindione. Approved Amoxicillin Amoxicillin may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Ampicillin Ampicillin may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Anagrelide Anagrelide may increase the anticoagulant activities of Fluindione. Approved Ancrod Ancrod may increase the anticoagulant activities of Fluindione. Approved, Investigational Andrographolide Andrographolide may increase the anticoagulant activities of Fluindione. Investigational Anisodamine Anisodamine may increase the anticoagulant activities of Fluindione. Investigational Anistreplase Anistreplase may increase the anticoagulant activities of Fluindione. Approved Antipyrine Antipyrine may increase the anticoagulant activities of Fluindione. Approved, Investigational Antithrombin III human Antithrombin III human may increase the anticoagulant activities of Fluindione. Approved Apixaban Apixaban may increase the anticoagulant activities of Fluindione. Approved Apocynin Apocynin may increase the anticoagulant activities of Fluindione. Investigational Apremilast Apremilast may increase the anticoagulant activities of Fluindione. Approved, Investigational Aprotinin The therapeutic efficacy of Fluindione can be decreased when used in combination with Aprotinin. Approved, Investigational, Withdrawn Ardeparin Ardeparin may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Argatroban Argatroban may increase the anticoagulant activities of Fluindione. Approved, Investigational Aspoxicillin Aspoxicillin may increase the anticoagulant activities of Fluindione. Experimental Astaxanthin Astaxanthin may increase the anticoagulant activities of Fluindione. Investigational Azapropazone Azapropazone may increase the anticoagulant activities of Fluindione. Withdrawn Azathioprine Azathioprine may decrease the anticoagulant activities of Fluindione. Approved Azelastine Azelastine may increase the anticoagulant activities of Fluindione. Approved Azficel-T The risk or severity of adverse effects can be increased when Fluindione is combined with Azficel-T. Approved, Investigational Azidocillin Azidocillin may increase the anticoagulant activities of Fluindione. Approved Azithromycin The serum concentration of Fluindione can be increased when it is combined with Azithromycin. Approved Azlocillin Azlocillin may increase the anticoagulant activities of Fluindione. Approved Bacampicillin Bacampicillin may increase the anticoagulant activities of Fluindione. Approved, Investigational Balsalazide Balsalazide may increase the anticoagulant activities of Fluindione. Approved, Investigational Barbexaclone The metabolism of Fluindione can be increased when combined with Barbexaclone. Experimental Barbital The metabolism of Fluindione can be increased when combined with Barbital. Illicit Batroxobin Batroxobin may increase the anticoagulant activities of Fluindione. Experimental Becaplermin Becaplermin may increase the anticoagulant activities of Fluindione. Approved, Investigational Bemiparin Bemiparin may increase the anticoagulant activities of Fluindione. Approved, Investigational Bendazac Bendazac may increase the anticoagulant activities of Fluindione. Experimental Benorilate Benorilate may increase the anticoagulant activities of Fluindione. Experimental Benoxaprofen Benoxaprofen may increase the anticoagulant activities of Fluindione. Withdrawn Benzathine benzylpenicillin Benzathine benzylpenicillin may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Benzydamine Benzydamine may increase the anticoagulant activities of Fluindione. Approved Benzylpenicillin Benzylpenicillin may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Benzylpenicilloyl Polylysine Benzylpenicilloyl Polylysine may increase the anticoagulant activities of Fluindione. Approved Beraprost Beraprost may increase the anticoagulant activities of Fluindione. Investigational Bevonium Bevonium may increase the anticoagulant activities of Fluindione. Experimental Bezafibrate Bezafibrate may increase the anticoagulant activities of Fluindione. Approved, Investigational Bicalutamide The serum concentration of Fluindione can be increased when it is combined with Bicalutamide. Approved Bivalirudin Bivalirudin may increase the anticoagulant activities of Fluindione. Approved, Investigational Bosentan The metabolism of Fluindione can be increased when combined with Bosentan. Approved, Investigational Brinase Brinase may increase the anticoagulant activities of Fluindione. Experimental Bromfenac Bromfenac may increase the anticoagulant activities of Fluindione. Approved Bucillamine Bucillamine may increase the anticoagulant activities of Fluindione. Investigational Bufexamac Bufexamac may increase the anticoagulant activities of Fluindione. Approved, Experimental Buflomedil Buflomedil may increase the anticoagulant activities of Fluindione. Experimental Bumadizone Bumadizone may increase the anticoagulant activities of Fluindione. Experimental Butriptyline Butriptyline may increase the anticoagulant activities of Fluindione. Approved Butylphthalide Butylphthalide may increase the anticoagulant activities of Fluindione. Investigational Cangrelor Cangrelor may increase the anticoagulant activities of Fluindione. Approved Capecitabine The serum concentration of Fluindione can be increased when it is combined with Capecitabine. Approved, Investigational Caplacizumab Caplacizumab may increase the anticoagulant activities of Fluindione. Investigational Carbamazepine The serum concentration of Fluindione can be decreased when it is combined with Carbamazepine. Approved, Investigational Carbaspirin calcium Carbaspirin calcium may increase the anticoagulant activities of Fluindione. Experimental, Investigational Carbenicillin Carbenicillin may increase the anticoagulant activities of Fluindione. Approved, Investigational Carbenicillin indanyl Carbenicillin indanyl may increase the anticoagulant activities of Fluindione. Approved, Investigational Carbimazole Carbimazole may decrease the anticoagulant activities of Fluindione. Approved, Investigational Carbomycin The serum concentration of Fluindione can be increased when it is combined with Carbomycin. Vet Approved Carbutamide Carbutamide may increase the anticoagulant activities of Fluindione. Experimental Carfecillin Carfecillin may increase the anticoagulant activities of Fluindione. Experimental Carprofen Carprofen may increase the anticoagulant activities of Fluindione. Approved, Vet Approved, Withdrawn Castanospermine Castanospermine may increase the anticoagulant activities of Fluindione. Experimental Cefacetrile Cefacetrile may increase the anticoagulant activities of Fluindione. Approved Cefaclor Cefaclor may increase the anticoagulant activities of Fluindione. Approved Cefadroxil Cefadroxil may increase the anticoagulant activities of Fluindione. Approved, Vet Approved, Withdrawn Cefalotin Cefalotin may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Cefamandole Cefamandole may increase the anticoagulant activities of Fluindione. Approved, Investigational Cefapirin Cefapirin may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Cefatrizine Cefatrizine may increase the anticoagulant activities of Fluindione. Experimental Cefazedone Cefazedone may increase the anticoagulant activities of Fluindione. Experimental Cefazolin Cefazolin may increase the anticoagulant activities of Fluindione. Approved Cefbuperazone Cefbuperazone may increase the anticoagulant activities of Fluindione. Experimental Cefetamet Cefetamet may increase the anticoagulant activities of Fluindione. Experimental Cefixime Cefixime may increase the anticoagulant activities of Fluindione. Approved, Investigational Cefmenoxime Cefmenoxime may increase the anticoagulant activities of Fluindione. Approved Cefmetazole Cefmetazole may increase the anticoagulant activities of Fluindione. Approved, Investigational Cefminox Cefminox may increase the anticoagulant activities of Fluindione. Approved Cefodizime Cefodizime may increase the anticoagulant activities of Fluindione. Experimental Cefonicid Cefonicid may increase the anticoagulant activities of Fluindione. Approved, Investigational Cefoperazone Cefoperazone may increase the anticoagulant activities of Fluindione. Approved, Investigational Ceforanide Ceforanide may increase the anticoagulant activities of Fluindione. Approved Cefotaxime Cefotaxime may increase the anticoagulant activities of Fluindione. Approved Cefotetan Cefotetan may increase the anticoagulant activities of Fluindione. Approved Cefotiam Cefotiam may increase the anticoagulant activities of Fluindione. Approved, Investigational Cefoxitin Cefoxitin may increase the anticoagulant activities of Fluindione. Approved Cefpodoxime Cefpodoxime may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Cefradine Cefradine may increase the anticoagulant activities of Fluindione. Approved Cefroxadine Cefroxadine may increase the anticoagulant activities of Fluindione. Withdrawn Cefsulodin Cefsulodin may increase the anticoagulant activities of Fluindione. Experimental Ceftazidime Ceftazidime may increase the anticoagulant activities of Fluindione. Approved Ceftezole Ceftezole may increase the anticoagulant activities of Fluindione. Experimental Ceftizoxime Ceftizoxime may increase the anticoagulant activities of Fluindione. Approved, Investigational Ceftobiprole Ceftobiprole may increase the anticoagulant activities of Fluindione. Approved, Investigational Ceftriaxone Ceftriaxone may increase the anticoagulant activities of Fluindione. Approved Cefuroxime Cefuroxime may increase the anticoagulant activities of Fluindione. Approved Celecoxib Celecoxib may increase the anticoagulant activities of Fluindione. Approved, Investigational Cephalexin Cephalexin may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Cephaloglycin Cephaloglycin may increase the anticoagulant activities of Fluindione. Approved Cephaloridine Cephaloridine may increase the anticoagulant activities of Fluindione. Approved, Withdrawn Certoparin Certoparin may increase the anticoagulant activities of Fluindione. Approved, Investigational Chloral hydrate The serum concentration of Fluindione can be increased when it is combined with Chloral hydrate. Approved, Illicit, Investigational, Vet Approved Chloramphenicol Chloramphenicol may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Chloroquine Chloroquine may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Chlorotrianisene Chlorotrianisene may decrease the anticoagulant activities of Fluindione. Investigational, Withdrawn Chlorpropamide Chlorpropamide may increase the anticoagulant activities of Fluindione. Approved, Investigational Chlortetracycline Chlortetracycline may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Cholestyramine Cholestyramine can cause a decrease in the absorption of Fluindione resulting in a reduced serum concentration and potentially a decrease in efficacy. Approved, Investigational Choline magnesium trisalicylate Choline magnesium trisalicylate may increase the anticoagulant activities of Fluindione. Approved Cilostazol Cilostazol may increase the anticoagulant activities of Fluindione. Approved, Investigational Cimetidine Cimetidine may increase the anticoagulant activities of Fluindione. Approved, Investigational Cinoxacin Cinoxacin may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Ciprofibrate Ciprofibrate may increase the anticoagulant activities of Fluindione. Approved, Investigational Citalopram Citalopram may increase the anticoagulant activities of Fluindione. Approved Citric Acid Citric Acid may increase the anticoagulant activities of Fluindione. Approved, Nutraceutical, Vet Approved Clarithromycin The serum concentration of Fluindione can be increased when it is combined with Clarithromycin. Approved Clofibrate Clofibrate may increase the anticoagulant activities of Fluindione. Approved, Investigational Clofibride Clofibride may increase the anticoagulant activities of Fluindione. Experimental Clomipramine Clomipramine may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Clonixin Clonixin may increase the anticoagulant activities of Fluindione. Approved Clopidogrel Clopidogrel may increase the anticoagulant activities of Fluindione. Approved Cloricromen Cloricromen may increase the anticoagulant activities of Fluindione. Experimental Clorindione Clorindione may increase the anticoagulant activities of Fluindione. Experimental Cloxacillin Cloxacillin may decrease the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Colesevelam Colesevelam can cause a decrease in the absorption of Fluindione resulting in a reduced serum concentration and potentially a decrease in efficacy. Approved Colestipol Colestipol can cause a decrease in the absorption of Fluindione resulting in a reduced serum concentration and potentially a decrease in efficacy. Approved Collagenase clostridium histolyticum The risk or severity of adverse effects can be increased when Fluindione is combined with Collagenase clostridium histolyticum. Approved, Investigational Conjugated estrogens Conjugated estrogens may decrease the anticoagulant activities of Fluindione. Approved Cranberry Cranberry may increase the anticoagulant activities of Fluindione. Approved, Investigational Curcumin Curcumin may increase the anticoagulant activities of Fluindione. Approved, Investigational Cyclacillin Cyclacillin may increase the anticoagulant activities of Fluindione. Approved Dabigatran etexilate Dabigatran etexilate may increase the anticoagulant activities of Fluindione. Approved Daidzein Daidzein may decrease the anticoagulant activities of Fluindione. Experimental Dalteparin Dalteparin may increase the anticoagulant activities of Fluindione. Approved Danaparoid Danaparoid may increase the anticoagulant activities of Fluindione. Approved, Withdrawn Danazol Danazol may increase the anticoagulant activities of Fluindione. Approved Dapoxetine Dapoxetine may increase the anticoagulant activities of Fluindione. Investigational Darexaban Darexaban may increase the anticoagulant activities of Fluindione. Investigational Dasatinib Dasatinib may increase the anticoagulant activities of Fluindione. Approved, Investigational Deferasirox The risk or severity of adverse effects can be increased when Fluindione is combined with Deferasirox. Approved, Investigational Defibrotide Defibrotide may increase the anticoagulant activities of Fluindione. Approved, Investigational Demeclocycline Demeclocycline may increase the anticoagulant activities of Fluindione. Approved Demegestone The therapeutic efficacy of Fluindione can be decreased when used in combination with Demegestone. Experimental Deoxycholic Acid The risk or severity of adverse effects can be increased when Fluindione is combined with Deoxycholic Acid. Approved Dersalazine Dersalazine may increase the anticoagulant activities of Fluindione. Investigational Desipramine Desipramine may increase the anticoagulant activities of Fluindione. Approved, Investigational Desirudin Desirudin may increase the anticoagulant activities of Fluindione. Approved Desmoteplase Desmoteplase may increase the anticoagulant activities of Fluindione. Investigational Desogestrel Desogestrel may decrease the anticoagulant activities of Fluindione. Approved Desvenlafaxine The risk or severity of adverse effects can be increased when Desvenlafaxine is combined with Fluindione. Approved, Investigational Dexmethylphenidate The serum concentration of Fluindione can be increased when it is combined with Dexmethylphenidate. Approved, Investigational Dextran Dextran may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Dibenzepin Dibenzepin may increase the anticoagulant activities of Fluindione. Experimental Diclofenac Diclofenac may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Dicloxacillin Dicloxacillin may decrease the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Dicoumarol Dicoumarol may increase the anticoagulant activities of Fluindione. Approved Dienestrol Dienestrol may decrease the anticoagulant activities of Fluindione. Approved, Investigational Dienogest Dienogest may decrease the anticoagulant activities of Fluindione. Approved Diethylstilbestrol Diethylstilbestrol may decrease the anticoagulant activities of Fluindione. Approved, Investigational Difenpiramide Difenpiramide may increase the anticoagulant activities of Fluindione. Experimental Diflunisal Diflunisal may increase the anticoagulant activities of Fluindione. Approved, Investigational Dimetacrine Dimetacrine may increase the anticoagulant activities of Fluindione. Approved, Withdrawn Diphenadione Diphenadione may increase the anticoagulant activities of Fluindione. Experimental Dipyridamole Dipyridamole may increase the anticoagulant activities of Fluindione. Approved Disulfiram The serum concentration of Fluindione can be increased when it is combined with Disulfiram. Approved Ditazole Ditazole may increase the anticoagulant activities of Fluindione. Approved, Withdrawn Dosulepin Dosulepin may increase the anticoagulant activities of Fluindione. Approved Doxepin Doxepin may increase the anticoagulant activities of Fluindione. Approved, Investigational Doxycycline Doxycycline may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Dronedarone The serum concentration of Fluindione can be increased when it is combined with Dronedarone. Approved Drospirenone Drospirenone may decrease the anticoagulant activities of Fluindione. Approved Drotrecogin alfa Drotrecogin alfa may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Droxicam Droxicam may increase the anticoagulant activities of Fluindione. Withdrawn Duloxetine Duloxetine may increase the anticoagulant activities of Fluindione. Approved Duvelisib Duvelisib may increase the anticoagulant activities of Fluindione. Investigational Dydrogesterone The therapeutic efficacy of Fluindione can be decreased when used in combination with Dydrogesterone. Approved, Investigational, Withdrawn E-6201 E-6201 may increase the anticoagulant activities of Fluindione. Investigational Econazole The serum concentration of Fluindione can be increased when it is combined with Econazole. Approved Edetic Acid Edetic Acid may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Edoxaban Edoxaban may increase the anticoagulant activities of Fluindione. Approved Efavirenz The serum concentration of Fluindione can be decreased when it is combined with Efavirenz. Approved, Investigational Enoxacin Enoxacin may increase the anticoagulant activities of Fluindione. Approved, Investigational Enoxaparin Enoxaparin may increase the anticoagulant activities of Fluindione. Approved Epicillin Epicillin may increase the anticoagulant activities of Fluindione. Experimental Epimestrol Epimestrol may decrease the anticoagulant activities of Fluindione. Experimental Epinastine Epinastine may increase the anticoagulant activities of Fluindione. Approved, Investigational Epirizole Epirizole may increase the anticoagulant activities of Fluindione. Approved Eplivanserin Eplivanserin may increase the anticoagulant activities of Fluindione. Investigational eplivanserine eplivanserine may increase the anticoagulant activities of Fluindione. Investigational Epoprostenol Epoprostenol may increase the anticoagulant activities of Fluindione. Approved Eptifibatide Eptifibatide may increase the anticoagulant activities of Fluindione. Approved, Investigational Equol Equol may decrease the anticoagulant activities of Fluindione. Investigational Erythromycin The serum concentration of Fluindione can be increased when it is combined with Erythromycin. Approved, Investigational, Vet Approved Escitalopram Escitalopram may increase the anticoagulant activities of Fluindione. Approved, Investigational Esomeprazole The serum concentration of Fluindione can be increased when it is combined with Esomeprazole. Approved, Investigational Estradiol Estradiol may decrease the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Estradiol acetate Estradiol acetate may decrease the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Estradiol cypionate Estradiol cypionate may decrease the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Estradiol valerate Estradiol valerate may decrease the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Estramustine Estramustine may decrease the anticoagulant activities of Fluindione. Approved, Investigational Estriol Estriol may decrease the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Estrogens, esterified Estrogens, esterified may decrease the anticoagulant activities of Fluindione. Approved Estrone Estrone may decrease the anticoagulant activities of Fluindione. Approved Estrone sulfate Estrone sulfate may decrease the anticoagulant activities of Fluindione. Approved Etacrynic acid The serum concentration of Fluindione can be increased when it is combined with Etacrynic acid. Approved, Investigational Etanercept Etanercept may increase the anticoagulant activities of Fluindione. Approved, Investigational Ethanol The serum concentration of Fluindione can be decreased when it is combined with Ethanol. Approved Ethenzamide Ethenzamide may increase the anticoagulant activities of Fluindione. Experimental Ethinyl Estradiol Ethinyl Estradiol may decrease the anticoagulant activities of Fluindione. Approved Ethotoin Ethotoin may increase the anticoagulant activities of Fluindione. Approved Ethyl biscoumacetate Ethyl biscoumacetate may increase the anticoagulant activities of Fluindione. Withdrawn Ethynodiol The therapeutic efficacy of Fluindione can be decreased when used in combination with Ethynodiol. Experimental Ethynodiol diacetate Ethynodiol diacetate may decrease the anticoagulant activities of Fluindione. Approved Etodolac Etodolac may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Etofenamate Etofenamate may increase the anticoagulant activities of Fluindione. Approved, Investigational Etofibrate Etofibrate may increase the anticoagulant activities of Fluindione. Approved Etonogestrel Etonogestrel may decrease the anticoagulant activities of Fluindione. Approved, Investigational Etoperidone Etoperidone may increase the anticoagulant activities of Fluindione. Withdrawn Etoposide Etoposide may increase the anticoagulant activities of Fluindione. Approved Etoricoxib Etoricoxib may increase the anticoagulant activities of Fluindione. Approved, Investigational Evening primrose oil Evening primrose oil may increase the anticoagulant activities of Fluindione. Investigational, Nutraceutical Exenatide Exenatide may increase the anticoagulant activities of Fluindione. Approved, Investigational Exisulind Exisulind may increase the anticoagulant activities of Fluindione. Investigational Felbinac Felbinac may increase the anticoagulant activities of Fluindione. Experimental Fenbufen Fenbufen may increase the anticoagulant activities of Fluindione. Approved Fenofibrate Fenofibrate may increase the anticoagulant activities of Fluindione. Approved Fenofibric acid Fenofibric acid may increase the anticoagulant activities of Fluindione. Approved Fenoprofen Fenoprofen may increase the anticoagulant activities of Fluindione. Approved Fentiazac Fentiazac may increase the anticoagulant activities of Fluindione. Experimental Feprazone Feprazone may increase the anticoagulant activities of Fluindione. Experimental Ferulic acid Ferulic acid may increase the anticoagulant activities of Fluindione. Experimental Fibrinolysin Fibrinolysin may increase the anticoagulant activities of Fluindione. Investigational Fleroxacin Fleroxacin may increase the anticoagulant activities of Fluindione. Approved Floctafenine Floctafenine may increase the anticoagulant activities of Fluindione. Approved, Withdrawn Flucloxacillin Flucloxacillin may decrease the anticoagulant activities of Fluindione. Approved, Investigational Fluconazole The serum concentration of Fluindione can be increased when it is combined with Fluconazole. Approved, Investigational Flumequine Flumequine may increase the anticoagulant activities of Fluindione. Withdrawn Flunixin Flunixin may increase the anticoagulant activities of Fluindione. Vet Approved Flunoxaprofen Flunoxaprofen may increase the anticoagulant activities of Fluindione. Experimental Fluorouracil The serum concentration of Fluindione can be increased when it is combined with Fluorouracil. Approved Fluoxetine Fluoxetine may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Fluoxymesterone Fluoxymesterone may increase the anticoagulant activities of Fluindione. Approved, Illicit Flurbiprofen Flurbiprofen may increase the anticoagulant activities of Fluindione. Approved, Investigational Fluvoxamine Fluvoxamine may increase the anticoagulant activities of Fluindione. Approved, Investigational Fondaparinux Fondaparinux may increase the anticoagulant activities of Fluindione. Approved, Investigational Fondaparinux sodium Fondaparinux sodium may increase the anticoagulant activities of Fluindione. Approved, Investigational Fosphenytoin Fosphenytoin may increase the anticoagulant activities of Fluindione. Approved, Investigational Fusidic Acid The serum concentration of Fluindione can be increased when it is combined with Fusidic Acid. Approved, Investigational Gabexate Gabexate may increase the anticoagulant activities of Fluindione. Investigational Garenoxacin Garenoxacin may increase the anticoagulant activities of Fluindione. Investigational Gatifloxacin Gatifloxacin may increase the anticoagulant activities of Fluindione. Approved, Investigational Gefitinib Gefitinib may increase the anticoagulant activities of Fluindione. Approved, Investigational Gemfibrozil Gemfibrozil may increase the anticoagulant activities of Fluindione. Approved Gemifloxacin Gemifloxacin may increase the anticoagulant activities of Fluindione. Approved, Investigational Genistein Genistein may decrease the anticoagulant activities of Fluindione. Investigational Gestodene Gestodene may decrease the anticoagulant activities of Fluindione. Approved, Investigational Gestonorone The therapeutic efficacy of Fluindione can be decreased when used in combination with Gestonorone. Experimental Gestrinone The therapeutic efficacy of Fluindione can be decreased when used in combination with Gestrinone. Approved Ginkgo biloba The risk or severity of adverse effects can be increased when Ginkgo biloba is combined with Fluindione. Approved, Investigational, Nutraceutical Glibornuride Glibornuride may increase the anticoagulant activities of Fluindione. Investigational, Withdrawn Gliclazide Gliclazide may increase the anticoagulant activities of Fluindione. Approved Glimepiride Glimepiride may increase the anticoagulant activities of Fluindione. Approved Glipizide Glipizide may increase the anticoagulant activities of Fluindione. Approved, Investigational Gliquidone Gliquidone may increase the anticoagulant activities of Fluindione. Approved, Investigational Glisoxepide Glisoxepide may increase the anticoagulant activities of Fluindione. Investigational GLPG-0492 GLPG-0492 may increase the anticoagulant activities of Fluindione. Investigational Glucagon recombinant Glucagon recombinant may increase the anticoagulant activities of Fluindione. Approved Glutethimide The metabolism of Fluindione can be increased when combined with Glutethimide. Approved, Illicit Glyburide Glyburide may increase the anticoagulant activities of Fluindione. Approved Grepafloxacin Grepafloxacin may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Griseofulvin The serum concentration of Fluindione can be decreased when it is combined with Griseofulvin. Approved, Investigational, Vet Approved Guacetisal Guacetisal may increase the anticoagulant activities of Fluindione. Experimental Hemin Hemin may increase the anticoagulant activities of Fluindione. Approved, Investigational Hemoglobin crosfumaril Hemoglobin crosfumaril may increase the anticoagulant activities of Fluindione. Experimental Heparin Heparin may increase the anticoagulant activities of Fluindione. Approved, Investigational Hexestrol Hexestrol may decrease the anticoagulant activities of Fluindione. Withdrawn Hexobarbital The metabolism of Fluindione can be increased when combined with Hexobarbital. Approved Higenamine Higenamine may increase the anticoagulant activities of Fluindione. Investigational Hydroxyprogesterone caproate The therapeutic efficacy of Fluindione can be decreased when used in combination with Hydroxyprogesterone caproate. Approved, Investigational Hydroxytyrosol Hydroxytyrosol may increase the anticoagulant activities of Fluindione. Investigational Ibritumomab tiuxetan The risk or severity of adverse effects can be increased when Fluindione is combined with Ibritumomab tiuxetan. Approved, Investigational Ibrutinib The risk or severity of adverse effects can be increased when Ibrutinib is combined with Fluindione. Approved Ibudilast Ibudilast may increase the anticoagulant activities of Fluindione. Approved, Investigational Ibuprofen Ibuprofen may increase the anticoagulant activities of Fluindione. Approved Ibuproxam Ibuproxam may increase the anticoagulant activities of Fluindione. Withdrawn Icatibant Icatibant may increase the anticoagulant activities of Fluindione. Approved, Investigational Icosapent ethyl Icosapent ethyl may increase the anticoagulant activities of Fluindione. Approved, Investigational, Nutraceutical Idraparinux Idraparinux may increase the anticoagulant activities of Fluindione. Investigational Ifenprodil Ifenprodil may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Ifetroban Ifetroban may increase the anticoagulant activities of Fluindione. Investigational Ifosfamide Ifosfamide may increase the anticoagulant activities of Fluindione. Approved Iloprost Iloprost may increase the anticoagulant activities of Fluindione. Approved, Investigational Imidazole salicylate Imidazole salicylate may increase the anticoagulant activities of Fluindione. Experimental Imipramine Imipramine may increase the anticoagulant activities of Fluindione. Approved Indalpine Indalpine may increase the anticoagulant activities of Fluindione. Investigational, Withdrawn Indobufen Indobufen may increase the anticoagulant activities of Fluindione. Investigational Indomethacin Indomethacin may increase the anticoagulant activities of Fluindione. Approved, Investigational Indoprofen Indoprofen may increase the anticoagulant activities of Fluindione. Withdrawn Iprindole Iprindole may increase the anticoagulant activities of Fluindione. Experimental Isoxicam Isoxicam may increase the anticoagulant activities of Fluindione. Withdrawn Itraconazole The serum concentration of Fluindione can be increased when it is combined with Itraconazole. Approved, Investigational Ivermectin Ivermectin may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Josamycin The serum concentration of Fluindione can be increased when it is combined with Josamycin. Approved, Investigational Kebuzone Kebuzone may increase the anticoagulant activities of Fluindione. Experimental Ketanserin Ketanserin may increase the anticoagulant activities of Fluindione. Investigational Ketoconazole The serum concentration of Fluindione can be increased when it is combined with Ketoconazole. Approved, Investigational Ketoprofen Ketoprofen may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Ketorolac Ketorolac may increase the anticoagulant activities of Fluindione. Approved Kitasamycin The serum concentration of Fluindione can be increased when it is combined with Kitasamycin. Experimental L-Carnitine L-Carnitine may increase the anticoagulant activities of Fluindione. Approved, Investigational Lansoprazole The serum concentration of Fluindione can be increased when it is combined with Lansoprazole. Approved, Investigational Leflunomide Leflunomide may increase the anticoagulant activities of Fluindione. Approved, Investigational Lepirudin Lepirudin may increase the anticoagulant activities of Fluindione. Approved Letaxaban Letaxaban may increase the anticoagulant activities of Fluindione. Investigational Levofloxacin Levofloxacin may increase the anticoagulant activities of Fluindione. Approved, Investigational Levomilnacipran The risk or severity of adverse effects can be increased when Levomilnacipran is combined with Fluindione. Approved, Investigational Levonorgestrel Levonorgestrel may decrease the anticoagulant activities of Fluindione. Approved, Investigational Levothyroxine Levothyroxine may increase the anticoagulant activities of Fluindione. Approved Limaprost The risk or severity of adverse effects can be increased when Limaprost is combined with Fluindione. Approved, Investigational Linsidomine Linsidomine may increase the anticoagulant activities of Fluindione. Experimental Liothyronine Liothyronine may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Liotrix Liotrix may increase the anticoagulant activities of Fluindione. Approved Lisofylline Lisofylline may increase the anticoagulant activities of Fluindione. Investigational Lixisenatide Lixisenatide can cause a decrease in the absorption of Fluindione resulting in a reduced serum concentration and potentially a decrease in efficacy. Approved Lofepramine Lofepramine may increase the anticoagulant activities of Fluindione. Experimental Lonazolac Lonazolac may increase the anticoagulant activities of Fluindione. Experimental Lornoxicam Lornoxicam may increase the anticoagulant activities of Fluindione. Approved, Investigational Loxoprofen Loxoprofen may increase the anticoagulant activities of Fluindione. Approved, Investigational Lumiracoxib Lumiracoxib may increase the anticoagulant activities of Fluindione. Approved, Investigational Lynestrenol Lynestrenol may decrease the anticoagulant activities of Fluindione. Approved, Investigational Magnesium salicylate Magnesium salicylate may increase the anticoagulant activities of Fluindione. Approved Masoprocol Masoprocol may increase the anticoagulant activities of Fluindione. Approved, Investigational Meclofenamic acid Meclofenamic acid may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Medrogestone The therapeutic efficacy of Fluindione can be decreased when used in combination with Medrogestone. Approved Medroxyprogesterone acetate Medroxyprogesterone acetate may decrease the anticoagulant activities of Fluindione. Approved, Investigational Mefenamic acid Mefenamic acid may increase the anticoagulant activities of Fluindione. Approved Megestrol acetate The therapeutic efficacy of Fluindione can be decreased when used in combination with Megestrol acetate. Approved, Investigational, Vet Approved Melagatran Fluindione may increase the anticoagulant activities of Melagatran. Experimental Melitracen Melitracen may increase the anticoagulant activities of Fluindione. Experimental, Investigational Meloxicam Meloxicam may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Mercaptopurine Mercaptopurine may decrease the anticoagulant activities of Fluindione. Approved Mesalazine Mesalazine may increase the anticoagulant activities of Fluindione. Approved Mesterolone Mesterolone may increase the anticoagulant activities of Fluindione. Experimental Mestranol Mestranol may decrease the anticoagulant activities of Fluindione. Approved Metahexamide Metahexamide may increase the anticoagulant activities of Fluindione. Experimental Metamizole Metamizole may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Metampicillin Metampicillin may increase the anticoagulant activities of Fluindione. Experimental Methallenestril Methallenestril may decrease the anticoagulant activities of Fluindione. Experimental Methimazole Methimazole may decrease the anticoagulant activities of Fluindione. Approved Methohexital The metabolism of Fluindione can be increased when combined with Methohexital. Approved Methyl salicylate Methyl salicylate may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Methylestrenolone The therapeutic efficacy of Fluindione can be decreased when used in combination with Methylestrenolone. Experimental Methylphenidate The serum concentration of Fluindione can be increased when it is combined with Methylphenidate. Approved, Investigational Methylphenobarbital The metabolism of Fluindione can be increased when combined with Methylphenobarbital. Approved Methyltestosterone Methyltestosterone may increase the anticoagulant activities of Fluindione. Approved Methylthiouracil Methylthiouracil may decrease the anticoagulant activities of Fluindione. Experimental Meticillin Meticillin may increase the anticoagulant activities of Fluindione. Approved, Investigational Metronidazole The serum concentration of Fluindione can be increased when it is combined with Metronidazole. Approved Mezlocillin Mezlocillin may increase the anticoagulant activities of Fluindione. Approved, Investigational Miconazole The serum concentration of Fluindione can be increased when it is combined with Miconazole. Approved, Investigational, Vet Approved Milnacipran The risk or severity of adverse effects can be increased when Milnacipran is combined with Fluindione. Approved, Investigational Milrinone Milrinone may increase the anticoagulant activities of Fluindione. Approved Minocycline Minocycline may increase the anticoagulant activities of Fluindione. Approved, Investigational Mizoribine Mizoribine may increase the anticoagulant activities of Fluindione. Investigational Mofebutazone Mofebutazone may increase the anticoagulant activities of Fluindione. Experimental Moxestrol Moxestrol may decrease the anticoagulant activities of Fluindione. Experimental Mycophenolate mofetil Mycophenolate mofetil may increase the anticoagulant activities of Fluindione. Approved, Investigational Mycophenolic acid Mycophenolic acid may increase the anticoagulant activities of Fluindione. Approved Nabumetone Nabumetone may increase the anticoagulant activities of Fluindione. Approved Nadroparin Nadroparin may increase the anticoagulant activities of Fluindione. Approved, Investigational Nafamostat Nafamostat may increase the anticoagulant activities of Fluindione. Approved, Investigational Nafcillin Nafcillin may decrease the anticoagulant activities of Fluindione. Approved, Investigational Naftifine Naftifine may increase the anticoagulant activities of Fluindione. Approved Naftopidil Naftopidil may increase the anticoagulant activities of Fluindione. Investigational Nalidixic Acid Nalidixic Acid may increase the anticoagulant activities of Fluindione. Approved, Investigational Nandrolone Nandrolone may increase the anticoagulant activities of Fluindione. Experimental, Investigational Nandrolone decanoate Nandrolone decanoate may increase the anticoagulant activities of Fluindione. Approved, Illicit Naproxen Naproxen may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Nefazodone Nefazodone may increase the anticoagulant activities of Fluindione. Approved, Withdrawn Nemonoxacin Nemonoxacin may increase the anticoagulant activities of Fluindione. Investigational Neomycin Neomycin may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Nepafenac Nepafenac may increase the anticoagulant activities of Fluindione. Approved, Investigational Nifenazone Nifenazone may increase the anticoagulant activities of Fluindione. Experimental Niflumic Acid Niflumic Acid may increase the anticoagulant activities of Fluindione. Approved Nimesulide Nimesulide may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Nintedanib The risk or severity of adverse effects can be increased when Fluindione is combined with Nintedanib. Approved Nitroaspirin Nitroaspirin may increase the anticoagulant activities of Fluindione. Investigational Nomegestrol The therapeutic efficacy of Fluindione can be decreased when used in combination with Nomegestrol. Approved Norelgestromin Norelgestromin may decrease the anticoagulant activities of Fluindione. Approved, Investigational Norethisterone The therapeutic efficacy of Fluindione can be decreased when used in combination with Norethisterone. Approved Norfloxacin Norfloxacin may increase the anticoagulant activities of Fluindione. Approved Norgestimate Norgestimate may decrease the anticoagulant activities of Fluindione. Approved, Investigational Norgestrel Norgestrel may decrease the anticoagulant activities of Fluindione. Approved Norgestrienone The therapeutic efficacy of Fluindione can be decreased when used in combination with Norgestrienone. Experimental Nortriptyline Nortriptyline may increase the anticoagulant activities of Fluindione. Approved Obinutuzumab The risk or severity of adverse effects can be increased when Fluindione is combined with Obinutuzumab. Approved, Investigational Oleandomycin The serum concentration of Fluindione can be increased when it is combined with Oleandomycin. Vet Approved Olopatadine Olopatadine may increase the anticoagulant activities of Fluindione. Approved Olsalazine Olsalazine may increase the anticoagulant activities of Fluindione. Approved Omacetaxine mepesuccinate The risk or severity of bleeding can be increased when Fluindione is combined with Omacetaxine mepesuccinate. Approved, Investigational Omega-3 fatty acids Omega-3 fatty acids may increase the anticoagulant activities of Fluindione. Approved, Nutraceutical Omega-3-carboxylic acids The therapeutic efficacy of Fluindione can be increased when used in combination with Omega-3-carboxylic acids. Approved, Investigational Omeprazole The serum concentration of Fluindione can be increased when it is combined with Omeprazole. Approved, Investigational, Vet Approved Opipramol Opipramol may increase the anticoagulant activities of Fluindione. Investigational Orgotein Orgotein may increase the anticoagulant activities of Fluindione. Vet Approved Oritavancin The serum concentration of Fluindione can be increased when it is combined with Oritavancin. Approved, Investigational Otamixaban Otamixaban may increase the anticoagulant activities of Fluindione. Investigational Oxacillin Oxacillin may increase the anticoagulant activities of Fluindione. Approved, Investigational Oxandrolone Oxandrolone may increase the anticoagulant activities of Fluindione. Approved, Investigational Oxaprozin Oxaprozin may increase the anticoagulant activities of Fluindione. Approved Oxolinic acid Oxolinic acid may increase the anticoagulant activities of Fluindione. Experimental Oxymetholone Oxymetholone may increase the anticoagulant activities of Fluindione. Approved, Illicit Oxyphenbutazone Oxyphenbutazone may increase the anticoagulant activities of Fluindione. Approved, Withdrawn Ozagrel Ozagrel may increase the anticoagulant activities of Fluindione. Investigational Parecoxib Parecoxib may increase the anticoagulant activities of Fluindione. Approved Parnaparin Parnaparin may increase the anticoagulant activities of Fluindione. Approved, Investigational Paroxetine Paroxetine may increase the anticoagulant activities of Fluindione. Approved, Investigational Parthenolide Parthenolide may increase the anticoagulant activities of Fluindione. Approved, Investigational Pazufloxacin Pazufloxacin may increase the anticoagulant activities of Fluindione. Investigational Pefloxacin Pefloxacin may increase the anticoagulant activities of Fluindione. Approved Penamecillin Penamecillin may increase the anticoagulant activities of Fluindione. Experimental Penimepicycline Penimepicycline may increase the anticoagulant activities of Fluindione. Experimental Pentaerythritol Tetranitrate Pentaerythritol Tetranitrate may increase the anticoagulant activities of Fluindione. Approved Pentobarbital The metabolism of Fluindione can be increased when combined with Pentobarbital. Approved, Investigational, Vet Approved Pentosan Polysulfate Pentosan Polysulfate may increase the anticoagulant activities of Fluindione. Approved Pentoxifylline Pentoxifylline may increase the anticoagulant activities of Fluindione. Approved, Investigational Phenindione Phenindione may increase the anticoagulant activities of Fluindione. Approved, Investigational Phenobarbital The metabolism of Fluindione can be increased when combined with Phenobarbital. Approved, Investigational Phenoxymethylpenicillin Phenoxymethylpenicillin may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Phenprocoumon Phenprocoumon may increase the anticoagulant activities of Fluindione. Approved, Investigational Phenyl aminosalicylate Phenyl aminosalicylate may increase the anticoagulant activities of Fluindione. Approved Phenylbutazone Phenylbutazone may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Phenytoin Phenytoin may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Phylloquinone Phylloquinone may decrease the anticoagulant activities of Fluindione. Approved, Investigational Picotamide Picotamide may increase the anticoagulant activities of Fluindione. Experimental Pimecrolimus Pimecrolimus may increase the anticoagulant activities of Fluindione. Approved, Investigational Pipemidic acid Pipemidic acid may increase the anticoagulant activities of Fluindione. Experimental Piperacillin Piperacillin may increase the anticoagulant activities of Fluindione. Approved Pirfenidone Pirfenidone may increase the anticoagulant activities of Fluindione. Approved, Investigational Piromidic acid Piromidic acid may increase the anticoagulant activities of Fluindione. Experimental Piroxicam Piroxicam may increase the anticoagulant activities of Fluindione. Approved, Investigational Pirprofen Pirprofen may increase the anticoagulant activities of Fluindione. Experimental Pivampicillin Pivampicillin may increase the anticoagulant activities of Fluindione. Approved Pivmecillinam Pivmecillinam may increase the anticoagulant activities of Fluindione. Approved Polyestradiol phosphate Polyestradiol phosphate may decrease the anticoagulant activities of Fluindione. Approved Posaconazole The serum concentration of Fluindione can be increased when it is combined with Posaconazole. Approved, Investigational, Vet Approved Potassium Iodide Potassium Iodide may decrease the anticoagulant activities of Fluindione. Approved Pranoprofen Pranoprofen may increase the anticoagulant activities of Fluindione. Experimental, Investigational Prasugrel Prasugrel may increase the anticoagulant activities of Fluindione. Approved Primidone The metabolism of Fluindione can be increased when combined with Primidone. Approved, Vet Approved Procaine benzylpenicillin Procaine benzylpenicillin may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Progesterone The therapeutic efficacy of Fluindione can be decreased when used in combination with Progesterone. Approved, Vet Approved Proglumetacin Proglumetacin may increase the anticoagulant activities of Fluindione. Experimental Promegestone The therapeutic efficacy of Fluindione can be decreased when used in combination with Promegestone. Experimental Promestriene Promestriene may decrease the anticoagulant activities of Fluindione. Investigational Propacetamol Propacetamol may increase the anticoagulant activities of Fluindione. Approved, Investigational Propafenone The serum concentration of Fluindione can be increased when it is combined with Propafenone. Approved Propicillin Propicillin may increase the anticoagulant activities of Fluindione. Experimental Propylthiouracil Propylthiouracil may decrease the anticoagulant activities of Fluindione. Approved, Investigational Propyphenazone Propyphenazone may increase the anticoagulant activities of Fluindione. Experimental Proquazone Proquazone may increase the anticoagulant activities of Fluindione. Experimental Protein C Protein C may increase the anticoagulant activities of Fluindione. Approved Protein S human Fluindione may increase the anticoagulant activities of Protein S human. Approved Protocatechualdehyde Protocatechualdehyde may increase the anticoagulant activities of Fluindione. Approved Protriptyline Protriptyline may increase the anticoagulant activities of Fluindione. Approved Prulifloxacin Prulifloxacin may increase the anticoagulant activities of Fluindione. Investigational PTC299 PTC299 may increase the anticoagulant activities of Fluindione. Investigational Quinestrol Quinestrol may decrease the anticoagulant activities of Fluindione. Approved Quinidine Quinidine may increase the anticoagulant activities of Fluindione. Approved, Investigational Quinine Quinine may increase the anticoagulant activities of Fluindione. Approved Ramatroban Ramatroban may increase the anticoagulant activities of Fluindione. Investigational Relcovaptan Relcovaptan may increase the anticoagulant activities of Fluindione. Investigational Resveratrol Resveratrol may increase the anticoagulant activities of Fluindione. Approved, Experimental, Investigational Reteplase Reteplase may increase the anticoagulant activities of Fluindione. Approved, Investigational Reviparin Reviparin may increase the anticoagulant activities of Fluindione. Approved, Investigational Ridogrel Ridogrel may increase the anticoagulant activities of Fluindione. Approved Rifabutin The metabolism of Fluindione can be increased when combined with Rifabutin. Approved, Investigational Rifampicin The metabolism of Fluindione can be increased when combined with Rifampicin. Approved Rifapentine The metabolism of Fluindione can be increased when combined with Rifapentine. Approved, Investigational Rifaximin The metabolism of Fluindione can be increased when combined with Rifaximin. Approved, Investigational Rivaroxaban Fluindione may increase the anticoagulant activities of Rivaroxaban. Approved Rofecoxib Rofecoxib may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Ronifibrate Ronifibrate may increase the anticoagulant activities of Fluindione. Experimental Rosiglitazone Rosiglitazone may increase the anticoagulant activities of Fluindione. Approved, Investigational Rosoxacin Rosoxacin may increase the anticoagulant activities of Fluindione. Approved, Investigational Rufloxacin Rufloxacin may increase the anticoagulant activities of Fluindione. Experimental Salicylamide Salicylamide may increase the anticoagulant activities of Fluindione. Approved Salicylic acid Salicylic acid may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Salsalate Salsalate may increase the anticoagulant activities of Fluindione. Approved Sarpogrelate Sarpogrelate may increase the anticoagulant activities of Fluindione. Investigational Saruplase Saruplase may increase the anticoagulant activities of Fluindione. Experimental Secobarbital The metabolism of Fluindione can be increased when combined with Secobarbital. Approved, Vet Approved Secoisolariciresinol Secoisolariciresinol may decrease the anticoagulant activities of Fluindione. Investigational Selexipag Selexipag may increase the anticoagulant activities of Fluindione. Approved Semapimod Semapimod may increase the anticoagulant activities of Fluindione. Investigational Seratrodast Seratrodast may increase the anticoagulant activities of Fluindione. Approved Serrapeptase Serrapeptase may increase the anticoagulant activities of Fluindione. Investigational Sertraline Sertraline may increase the anticoagulant activities of Fluindione. Approved Sevoflurane Sevoflurane may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Simfibrate Simfibrate may increase the anticoagulant activities of Fluindione. Experimental Sitafloxacin Sitafloxacin may increase the anticoagulant activities of Fluindione. Experimental, Investigational Solithromycin The serum concentration of Fluindione can be increased when it is combined with Solithromycin. Investigational Sparfloxacin Sparfloxacin may increase the anticoagulant activities of Fluindione. Approved, Investigational SRT501 SRT501 may increase the anticoagulant activities of Fluindione. Investigational St. John's Wort The metabolism of Fluindione can be increased when combined with St. John's Wort. Approved, Investigational, Nutraceutical Stanolone Stanolone may increase the anticoagulant activities of Fluindione. Illicit, Investigational Stanozolol Stanozolol may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Streptokinase The risk or severity of hemorrhage can be increased when Streptokinase is combined with Fluindione. Approved, Investigational Sucralfate Sucralfate may decrease the anticoagulant activities of Fluindione. Approved Sugammadex Sugammadex may increase the anticoagulant activities of Fluindione. Approved Sulbactam Sulbactam may increase the anticoagulant activities of Fluindione. Approved Sulbenicillin Sulbenicillin may increase the anticoagulant activities of Fluindione. Experimental Sulfadiazine Sulfadiazine may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Sulfamethoxazole Sulfamethoxazole may increase the anticoagulant activities of Fluindione. Approved Sulfasalazine Sulfasalazine may increase the anticoagulant activities of Fluindione. Approved Sulfinpyrazone The metabolism of Fluindione can be decreased when combined with Sulfinpyrazone. Approved Sulfisoxazole Sulfisoxazole may increase the anticoagulant activities of Fluindione. Approved, Vet Approved Sulindac Sulindac may increase the anticoagulant activities of Fluindione. Approved, Investigational Sulodexide Sulodexide may increase the anticoagulant activities of Fluindione. Approved, Investigational Sultamicillin Sultamicillin may increase the anticoagulant activities of Fluindione. Approved, Investigational Suprofen Suprofen may increase the anticoagulant activities of Fluindione. Approved, Withdrawn Suxibuzone Suxibuzone may increase the anticoagulant activities of Fluindione. Experimental Synthetic Conjugated Estrogens, A Synthetic Conjugated Estrogens, A may decrease the anticoagulant activities of Fluindione. Approved Synthetic Conjugated Estrogens, B Synthetic Conjugated Estrogens, B may decrease the anticoagulant activities of Fluindione. Approved Talampicillin Talampicillin may increase the anticoagulant activities of Fluindione. Experimental Tamoxifen Tamoxifen may increase the anticoagulant activities of Fluindione. Approved Tarenflurbil Tarenflurbil may increase the anticoagulant activities of Fluindione. Investigational Tazobactam Tazobactam may increase the anticoagulant activities of Fluindione. Approved Tegafur The serum concentration of Fluindione can be increased when it is combined with Tegafur. Approved, Investigational Telithromycin The serum concentration of Fluindione can be increased when it is combined with Telithromycin. Approved Temafloxacin Temafloxacin may increase the anticoagulant activities of Fluindione. Withdrawn Tenecteplase Tenecteplase may increase the anticoagulant activities of Fluindione. Approved Tenidap Tenidap may increase the anticoagulant activities of Fluindione. Experimental Tenoxicam Tenoxicam may increase the anticoagulant activities of Fluindione. Approved Tepoxalin Tepoxalin may increase the anticoagulant activities of Fluindione. Vet Approved Teriflunomide Teriflunomide may increase the anticoagulant activities of Fluindione. Approved Tesmilifene Tesmilifene may increase the anticoagulant activities of Fluindione. Investigational Testosterone Testosterone may increase the anticoagulant activities of Fluindione. Approved, Investigational Testosterone cypionate The therapeutic efficacy of Fluindione can be increased when used in combination with Testosterone cypionate. Approved Testosterone enanthate The therapeutic efficacy of Fluindione can be increased when used in combination with Testosterone enanthate. Approved Testosterone propionate Testosterone propionate may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved, Withdrawn Testosterone undecanoate The therapeutic efficacy of Fluindione can be increased when used in combination with Testosterone undecanoate. Approved, Investigational Thiamylal The metabolism of Fluindione can be increased when combined with Thiamylal. Approved, Vet Approved Thiopental The metabolism of Fluindione can be increased when combined with Thiopental. Approved, Vet Approved Thyroid, porcine Thyroid, porcine may increase the anticoagulant activities of Fluindione. Approved Tianeptine Tianeptine may increase the anticoagulant activities of Fluindione. Approved, Investigational Tiaprofenic acid Tiaprofenic acid may increase the anticoagulant activities of Fluindione. Approved Tibolone Tibolone may increase the anticoagulant activities of Fluindione. Approved, Investigational Ticagrelor Ticagrelor may increase the anticoagulant activities of Fluindione. Approved Ticarcillin Ticarcillin may increase the anticoagulant activities of Fluindione. Approved, Investigational, Vet Approved Ticlopidine Ticlopidine may increase the anticoagulant activities of Fluindione. Approved Tinoridine Tinoridine may increase the anticoagulant activities of Fluindione. Investigational Tinzaparin Tinzaparin may increase the anticoagulant activities of Fluindione. Approved Tioclomarol Tioclomarol may increase the anticoagulant activities of Fluindione. Experimental Tipranavir Tipranavir may increase the anticoagulant activities of Fluindione. Approved, Investigational Tirofiban Tirofiban may increase the anticoagulant activities of Fluindione. Approved Tolazamide Tolazamide may increase the anticoagulant activities of Fluindione. Approved, Investigational Tolbutamide Tolbutamide may increase the anticoagulant activities of Fluindione. Approved, Investigational Tolfenamic Acid Tolfenamic Acid may increase the anticoagulant activities of Fluindione. Approved, Investigational Tolmetin Tolmetin may increase the anticoagulant activities of Fluindione. Approved Toremifene Toremifene may increase the anticoagulant activities of Fluindione. Approved, Investigational Tositumomab The risk or severity of adverse effects can be increased when Fluindione is combined with Tositumomab. Approved, Investigational Tramadol Tramadol may increase the anticoagulant activities of Fluindione. Approved, Investigational Tranilast Tranilast may increase the anticoagulant activities of Fluindione. Approved, Investigational Trapidil Trapidil may increase the anticoagulant activities of Fluindione. Approved Treprostinil Treprostinil may increase the anticoagulant activities of Fluindione. Approved, Investigational Tribenoside Tribenoside may increase the anticoagulant activities of Fluindione. Experimental Triflusal Triflusal may increase the anticoagulant activities of Fluindione. Approved, Investigational Trimipramine Trimipramine may increase the anticoagulant activities of Fluindione. Approved Triptolide Triptolide may increase the anticoagulant activities of Fluindione. Investigational Trolamine salicylate Trolamine salicylate may increase the anticoagulant activities of Fluindione. Approved Trovafloxacin Trovafloxacin may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Troxerutin Troxerutin may increase the anticoagulant activities of Fluindione. Investigational Tylosin The serum concentration of Fluindione can be increased when it is combined with Tylosin. Vet Approved Urokinase Urokinase may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Valdecoxib Valdecoxib may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Venlafaxine The risk or severity of adverse effects can be increased when Venlafaxine is combined with Fluindione. Approved Vitamin E Vitamin E may increase the anticoagulant activities of Fluindione. Approved, Nutraceutical, Vet Approved Vorapaxar The risk or severity of adverse effects can be increased when Vorapaxar is combined with Fluindione. Approved Voriconazole The serum concentration of Fluindione can be increased when it is combined with Voriconazole. Approved, Investigational Vorinostat Vorinostat may increase the anticoagulant activities of Fluindione. Approved, Investigational Warfarin Warfarin may increase the anticoagulant activities of Fluindione. Approved Ximelagatran Ximelagatran may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Zafirlukast The serum concentration of Fluindione can be increased when it is combined with Zafirlukast. Approved, Investigational Zaltoprofen Zaltoprofen may increase the anticoagulant activities of Fluindione. Approved, Investigational Zeranol Zeranol may decrease the anticoagulant activities of Fluindione. Vet Approved Zileuton Zileuton may increase the anticoagulant activities of Fluindione. Approved, Investigational, Withdrawn Zimelidine Zimelidine may increase the anticoagulant activities of Fluindione. Withdrawn Zomepirac Zomepirac may increase the anticoagulant activities of Fluindione. Withdrawn - Food Interactions
- Not Available
References
- General References
- Not Available
- External Links
- PubChem Compound
- 68942
- PubChem Substance
- 347829254
- ChemSpider
- 62167
- BindingDB
- 50280156
- ChEBI
- 134975
- ChEMBL
- CHEMBL24924
- Wikipedia
- Fluindione
- ATC Codes
- B01AA12 — Fluindione
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Recruiting Treatment Nonvalvular Atrial Fibrillation 1 4 Completed Treatment Disorders, Blood Coagulation 1 4 Completed Treatment Nonvalvular Atrial Fibrillation 1 4 Recruiting Treatment Anticoagulating Treatment on a Duration at Least 12-month-old Superior / Anticoagulation Treatment at Least > or = to 12-month / Permanent Atrial Fibrillation / Pulmonary Embolism (PE) / Thrombosis, Venous 1 Not Available Recruiting Not Available Pulmonary Arterial Hypertension (PAH) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.0549 mg/mL ALOGPS logP 3.09 ALOGPS logP 3.02 ChemAxon logS -3.6 ALOGPS pKa (Strongest Acidic) 4.19 ChemAxon pKa (Strongest Basic) -7.5 ChemAxon Physiological Charge -1 ChemAxon Hydrogen Acceptor Count 2 ChemAxon Hydrogen Donor Count 0 ChemAxon Polar Surface Area 34.14 Å2 ChemAxon Rotatable Bond Count 1 ChemAxon Refractivity 65.45 m3·mol-1 ChemAxon Polarizability 23.35 Å3 ChemAxon Number of Rings 3 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter Yes ChemAxon Veber's Rule Yes ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Taxonomy
- Description
- This compound belongs to the class of organic compounds known as indanediones. These are compounds containing an indane ring bearing two ketone groups.
- Kingdom
- Organic compounds
- Super Class
- Benzenoids
- Class
- Indanes
- Sub Class
- Indanones
- Direct Parent
- Indanediones
- Alternative Parents
- Aryl alkyl ketones / Fluorobenzenes / Beta-diketones / Aryl fluorides / Organofluorides / Organic oxides / Hydrocarbon derivatives
- Substituents
- Indanedione / Aryl ketone / Aryl alkyl ketone / Fluorobenzene / Halobenzene / 1,3-diketone / 1,3-dicarbonyl compound / Aryl fluoride / Monocyclic benzene moiety / Aryl halide
- Molecular Framework
- Aromatic homopolycyclic compounds
- External Descriptors
- Not Available
Drug created on October 20, 2016 21:35 / Updated on May 02, 2018 00:29