Showing BioInteractions for Semaglutide (DB13928)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Semaglutide is a Glucagon-like peptide 1 receptor agonist | ||
| 1 | Glucagon-like peptide 1 receptor agonists | Albiglutide, Dulaglutide, Exenatide, Glucagon, Liraglutide, Lixisenatide |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Semaglutide is a Dipeptidyl peptidase 4 substrate | ||
| 1 | Dipeptidyl peptidase 4 inhibitors | Alogliptin, Atorvastatin, Linagliptin, Saxagliptin, Sitagliptin, Vildagliptin |
| 2 | Dipeptidyl peptidase 4 substrates | Exenatide, Liraglutide |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Semaglutide is a Neprilysin substrate | ||
| 1 | Neprilysin inhibitors | Candoxatril, Candoxatrilat, Phosphoramidon, Sacubitril, Thiorphan |
| 2 | Neprilysin substrates | Liraglutide |
| 3 | Neprilysin antagonists | Sacubitril |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Semaglutide is a Lipoprotein lipase inhibitor | ||
| 1 | Lipoprotein lipase inhibitors | Tyloxapol |
| 2 | Lipoprotein lipase stimulators | Omega-3-carboxylic acids |
| 3 | Lipoprotein lipase inducers | Glycyrrhizic acid |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Semaglutide is a Alpha-amylase 1 inhibitor | ||