Pulmonary Edemas

Also known as: Pulmonary oedema / Pulmonary Edema / Edema, Pulmonary / Pulmonary oedemas / Oedema, Pulmonary / Oedema lung / Edema lung / Lung oedema / Lung edema / Oedema pulmonary / Pulmonary oedema NOS / Congestion - lung / Pulmonary congestion (chronic) (passive) / Edema pulmonary

DrugDrug NameDrug Description
DB01115NifedipineNifedipine has been formulated as both a long- and short-acting 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nifedipine prevents calcium-dependent myocyte contraction and vasoconstriction. A second proposed mechanism for the drug’s vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth muscle carbonic anhydrase. Nifedipine is used to treat hypertension and chronic stable angina.
DrugDrug NamePhaseStatusCount
DB01001Salbutamol2Completed1
DB00203Sildenafil2Recruiting1
DB09153Sodium chloride2Completed1
DB00653Magnesium sulfate3Completed1
DB00841Dobutamine4Recruiting1
DB00235Milrinone4Recruiting1
DB04899Nesiritide4Withdrawn1
DB00819AcetazolamideNot AvailableCompleted1
DB00820TadalafilNot AvailableCompleted1