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Reactions
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Displaying reactions
1981 - 2010
of
3773
in total
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Substrate
Enzyme
Products
Clear
Ivacaftor
DB08820
Cytochrome P450 3A4
/
Cytochrome P450 3A5
M1 (hydroxymethyl-ivacaftor)
Details
Ivermectin
DB00602
Cytochrome P450 3A4
3''-o-Desmethyl-ivermectin B1a
Details
Ivermectin
DB00602
Cytochrome P450 3A4
3''-o-Desmethyl-ivermectin B1b
Details
Ivosidenib
DB14568
Not Available
Ivosidenib M39 metabolite
Details
Ivosidenib
DB14568
Not Available
Ivosidenib M30 metabolite
Details
Ivosidenib M39 metabolite
DBMET03503
Not Available
Ivosidenib M37 metabolite
Details
Ketamine
DB01221
Not Available
6-Hydroxyketamine
Details
Ketamine
DB01221
Not Available
5-Hydroxyketamine
Details
Ketamine
DB01221
Not Available
4-Hydroxyketamine
Details
Ketamine
DB01221
Cytochrome P450 2C9
/
Cytochrome P450 2B6
/
Cytochrome P450 3A4
Norketamine
Details
Ketobemidone
DB06738
Prostaglandin G/H synthase 1
Reduced ketobemidone
Details
Ketobemidone
DB06738
Prostaglandin G/H synthase 1
Dihydroxy ketobemidone
Details
Ketobemidone
DB06738
Cytochrome P450 2C9
/
Cytochrome P450 3A4
Norketobemidone
Details
Ketobemidone
DB06738
Prostaglandin G/H synthase 1
Ketobemidone N-oxide
Details
Ketoconazole
DB01026
Cytochrome P450 3A4
M7 (Ketoconazole)
Details
Ketoconazole
DB01026
Not Available
M9 (Ketoconazole)
Details
Ketoconazole
DB01026
Cytochrome P450 3A4
M13 (Ketoconazole)
Details
Ketoconazole
DB01026
Not Available
M14 (Ketoconazole)
Details
Ketoconazole
DB01026
Cytochrome P450 3A4
M8 (Ketoconazole)
Details
Ketoconazole
DB01026
Not Available
Ketoconazole epoxide intermediate
Details
Ketoconazole dihydroxyl intermediate
DBMET02665
Not Available
M3 (Ketoconazole)
Details
Ketoconazole dihydroxyl intermediate
DBMET02665
Not Available
M5' (Ketoconazole)
Details
Ketoconazole epoxide intermediate
DBMET02660
Not Available
Ketoconazole ketone intermediate
Details
Ketoconazole epoxide intermediate
DBMET02660
Not Available
Ketoconazole dihydroxyl intermediate
Details
Ketoconazole ketone hydroxyl intermediate
DBMET02662
Cytochrome P450 3A4
/
Cytochrome P450 2D6
M2 (Ketoconazole)
Details
Ketoconazole ketone hydroxyl intermediate
DBMET02662
Not Available
M5 (Ketoconazole)
Details
Ketoconazole ketone intermediate
DBMET02661
Not Available
Ketoconazole ketone hydroxyl intermediate
Details
Ketoprofen
DB01009
Not Available
Ketoprofen glucuronide
Details
Ketorolac
DB00465
Not Available
4-hydroxy ketorolac
Details
Ketorolac
DB00465
UDP-glucuronosyltransferase 2B7
rac Ketorolac Glucuronide
Details
Displaying reactions
1981 - 2010
of
3773
in total
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71
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