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Displaying drugs 1 - 25 of 962 in total
Antithrombin III human
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Synonyms: … Heparin cofactor B ... Antithrombin III (human) ... Antithrombin III human …
Matched Name: … Antithrombin III human …
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Name: … Antithrombin III human …
Matched Description: … A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Human interferon beta
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … HUMAN INTERFERON BETA ... Interferon beta (human) …
Matched Name: … Human interferon beta …
Matched Description: … Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis ... (MS), and was initially approved by the FDA in 1992. ... [L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Name: … Human interferon beta …
Matched Description: … Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis ... (MS), and was initially approved by the FDA in 1992. ... [L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Human botulinum neurotoxin A/B immune globulin
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin IV human ... Botulism immune globulin intravenous (human) ... Human-derived botulism antitoxin antibodies …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... 2003[L39814] and has since been used to treat more than 2100 cases of infant botulism. …
Matched Categories: … Human Immunoglobulin G …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … [L39819,L39824] BabyBIG (human-derived botulism immunoglobulin) was approved for use by the FDA in ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma ... 2003[L39814] and has since been used to treat more than 2100 cases of infant botulism. …
Matched Categories: … Human Immunoglobulin G …
Human papillomavirus type 11 L1 capsid protein antigen
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 11 Vaccine ... Recombinant human papillomavirus type 11 L1 protein …
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] ... GARDASİL 9 IM ENJEKSİYONLUK SÜSPANSİYON, 1 ADET ŞIRINGA+2 ADET İĞNE …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human ... Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] ... GARDASİL 9 IM ENJEKSİYONLUK SÜSPANSİYON, 1 ADET ŞIRINGA+2 ADET İĞNE …
Matched Categories: … Inactivated Human Papillomavirus Vaccine …
Human papillomavirus type 58 L1 capsid protein antigen
Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 58 Vaccine ... Recombinant human papillomavirus type 58 L1 protein …
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) type 58. ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] ... GARDASİL 9 IM ENJEKSİYONLUK SÜSPANSİYON, 1 ADET ŞIRINGA+2 ADET İĞNE …
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) type 58. ... It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular …
Matched Mixtures name: … Gardasil 9 [Human Papillomavirus 9-valent Vaccine, Recombinant] ... GARDASİL 9 IM ENJEKSİYONLUK SÜSPANSİYON, 1 ADET ŞIRINGA+2 ADET İĞNE …
Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen
Approved
Investigational
Matched Name: … Human papillomavirus type 16 L1 capsid protein residues 2-471 antigen …
Apadamtase alfa
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs ... Recombinant human adamts13 ... Metalloproteinase ADAMTS13 (human recombinant BAX930) …
Matched Description: … metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible for cleaving ... rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … metalloproteinase with a thrombospondin type 1 motif, member 13), which is responsible for cleaving ... rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... large von Willebrand factor multimers and preventing the formation of microthrombi - this deficiency …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
CVac
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
Plasminogen
Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved
Matched Synonyms: … 1-glutamylplasminogen ... Human plasminogen ... plasminogen, human-tvmh …
Matched Description: … )[L34620] for the treatment of type 1 plasminogen deficiency (hypoplasminogenemia). ... [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh ... [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … )[L34620] for the treatment of type 1 plasminogen deficiency (hypoplasminogenemia). ... [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh ... [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Elotuzumab
Elotuzumab is a humanized IgG1 (Immunoglobulin G) monoclonal antibody indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received one to three prior therapies. Elotuzumab targets SLAMF7, also known as Signaling Lymphocytic Activation Molecule Family member 7, a cell surface glycoprotein. Elotuzumab...
Approved
Matched Synonyms: … Immunoglobulin G1, anti-(human protein CS1) (human-mouse HuLuc63 heavy chain), disulfide with human-mouse …
Matched Description: … consists of the complementary determining regions (CDR) of the mouse antibody, MuLuc63, grafted onto human ... Food and Drug Administration. ... IgG1 heavy and kappa light chain frameworks. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … consists of the complementary determining regions (CDR) of the mouse antibody, MuLuc63, grafted onto human ... Food and Drug Administration. ... IgG1 heavy and kappa light chain frameworks. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Conestat alfa
C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Synonyms: … Recombinant human C1-INH ... Recombinant human C1 inhibitor ... Recombinant human C1-inhibitor …
Matched Description: … C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase ... tPA and plasmin within the fibrinolytic pathway. ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … RUCONEST 2100 U IV ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 ADET …
Matched Description: … C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase ... tPA and plasmin within the fibrinolytic pathway. ... Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … RUCONEST 2100 U IV ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 ADET …
Nirsevimab
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry...
Approved
Investigational
Matched Synonyms: … monoclonal antibody.gamma.1 heavy chain (1-456) (human vh (homo sapiens ighv1-69*01(ighd)-ighj4*01 ( ... 90.1%)) (8.8.19) (1-126) -homo sapiens ighg1*03 ... Immunoglobulin g1-kappa, anti-(human respiratory syncytial virus fusion glycoprotein f0 (protein f))human …
Matched Description: … neutralizes several RSV A and B strains. ... Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used ... to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Matched Description: … neutralizes several RSV A and B strains. ... Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ĸ) monoclonal antibody used ... to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins …
Insulin aspart
Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin, aspart, human ... Insulin, aspart protamine, human …
Matched Description: … Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune …
Matched Mixtures name: … RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 ... NOVORAPİD 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Matched Description: … Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... Insulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune …
Matched Mixtures name: … RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 ... NOVORAPİD 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Synonyms: … WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 LIGHT CHAIN, DIMER ... WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18/CHO LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(GANGLIOSIDE GD2) (HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 HEAVY CHAIN), DISULFIDE …
Matched Description: … constant regions of human IgG1 heavy-chain and kappa light-chain. ... on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted ... Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … constant regions of human IgG1 heavy-chain and kappa light-chain. ... on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted ... Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Parathyroid hormone
Parathyroid hormone (PTH) is a single-chain polypeptide composed of 84 amino acids. Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence, leaving the mature protein as a single-chain 84 amino-acids...
Approved
Investigational
Matched Synonyms: … Parathyroid hormone (1-84) human recombinant ... Parathormone (human recombinant) ... PTH(1-84) …
Matched Description: … Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion ... Food and Drug Administration (FDA). ... The name Preos and the New Drug Application is pending approval by the U.S. …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Parathyroid Hormones and Analogues ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Available as Preotact, it is an identical form of human recombinant hormome which produced as a fusion ... Food and Drug Administration (FDA). ... The name Preos and the New Drug Application is pending approval by the U.S. …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Parathyroid Hormones and Analogues ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Moroctocog alfa
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Synonyms: … Human factor VIII, recombinant B-domain deleted ... Antihemphilic factor, recombinant human B-domain deleted ... B-domain deleted recombinant factor VIII …
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant ... Moroctocog alfa is identical in sequence to endogenously produced Factor VIII, but does not contain the B-domain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … REFACTO AF 500 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUC FLAKON, 1 ADET ... REFACTO AF 250 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU FLAKON, 1 ADET ... REFACTO AF 1000 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU FLAKON, 1 ADET …
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant ... Moroctocog alfa is identical in sequence to endogenously produced Factor VIII, but does not contain the B-domain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … REFACTO AF 500 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUC FLAKON, 1 ADET ... REFACTO AF 250 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU FLAKON, 1 ADET ... REFACTO AF 1000 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU FLAKON, 1 ADET …
Drotrecogin alfa
Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and a light chain linked by a disulfide bond. Drotrecogin alfa was withdrawn from the market after a major study indicated...
Approved
Investigational
Withdrawn
Matched Synonyms: … Blood coagulation factor XIV (human) ... Recombinant human activated protein C (rH-APC) …
Matched Description: … Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. ... It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Description: … Drotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. ... It is a glycoprotein of approximately 55 kilodalton molecular weight, consisting of a heavy chain and …
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Beremagene geperpavec
Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Synonyms: … Dna (recombinant herpes simplex virus type 1 strain kos plasmid vector kb103 human collagen col7a1-specifying ... B-VEC …
Matched Description: … Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector …
Matched Categories: … Cellular and Gene Therapy …
Matched Description: … Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector …
Matched Categories: … Cellular and Gene Therapy …
Valoctocogene roxaparvovec
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 5 vector BMN 270 human blood-coagulation factor VIII SQ variant-specifying …
Matched Description: … deleted SQ form of human coagulation factor VIII (hFVIII-SQ). ... roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain ... [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for …
Matched Categories: … Cellular and Gene Therapy ... Amino Acids, Peptides, and Proteins …
Matched Description: … deleted SQ form of human coagulation factor VIII (hFVIII-SQ). ... roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain ... [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for …
Matched Categories: … Cellular and Gene Therapy ... Amino Acids, Peptides, and Proteins …
Elranatamab
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … B-CELL MATURATION ANTIGEN (BCMA) CLUSTER OF DIFFERENTIATION 3 (CD3) BISPECIFIC MONOCLONAL ANTIBODY (MAB ... ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL SURFACE ANTIGEN T3/LEU-4 ... -CHAIN) (HUMAN-MUS MUSCULUS MONOCLONAL PF-06863059 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS …
Matched Description: … Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. ... The resulting 4-chain bispecific antibody is covalently linked via five inter-chain disulfide bonds. ... immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager …
Matched Description: … Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. ... The resulting 4-chain bispecific antibody is covalently linked via five inter-chain disulfide bonds. ... immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager …
Sulesomab
Market product is Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes.
Approved
Matched Synonyms: … Immunoglobulin G1 (mouse monoclonal IMMU-MN3 Fab' fragment gamma-chain anti-human NCA-90 granulocyte …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Inflammation and Infection Detection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Inflammation and Infection Detection …
Beroctocog alfa
Approved
Investigational
Matched Categories: … Human Antihemophilic Factors ... Amino Acids, Peptides, and Proteins …
Matched Products: … HEMOFIL M ANTIHEMOPHILIC FACTOR (HUMAN), METHOD M, ... FEIBA 1000 U IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... FEIBA 500 U IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Matched Products: … HEMOFIL M ANTIHEMOPHILIC FACTOR (HUMAN), METHOD M, ... FEIBA 1000 U IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... FEIBA 500 U IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Rotavirus vaccine
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially ... Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. ... [L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain. …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …
Matched Products: … ROTARIX ORAL SÜSPANSIYON HAZIRLAMAK IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADET …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …
Matched Products: … ROTARIX ORAL SÜSPANSIYON HAZIRLAMAK IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADET …
Efmoroctocog alfa
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Description: … is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... VIII, but does not contain the B-domain, which has no known biological function, and [DB13192], which ... The B domain of factor VIII is deleted. …
Matched Categories: … Human Antihemophilic Factors …
Matched Categories: … Human Antihemophilic Factors …
Darunavir
Darunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as ritonavir for the effective management of HIV-1 infection. As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. Darunavir is being...
Approved
Matched Synonyms: … (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy ... (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-neopentylphenylsulfonamido)-3-hydroxy ... (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido …
Matched Iupac: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido ... ]-1-phenylbutan-2-yl]carbamate …
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] ... with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 …
Matched Salts cas: … 2281870-65-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... darunavir and ritonavir ... darunavir and cobicistat ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Darunavir 600 and 800 mg …
Matched Iupac: … (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido ... ]-1-phenylbutan-2-yl]carbamate …
Matched Description: … [A191682] Clinical trials are underway and are expected to conclude in August 2020.[L12066] ... with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 …
Matched Salts cas: … 2281870-65-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... darunavir and ritonavir ... darunavir and cobicistat ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Darunavir 600 and 800 mg …
Displaying drugs 1 - 25 of 962 in total