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Displaying drugs 1 - 25 of 7231 in total

Sodium phosphate P 32

Approved
Matched Synonyms: … Sodium phosphate P 32 ... Sodium phosphate P-32 …
Matched Name: … Sodium phosphate P 32 …

p-tert-Butylphenol-formaldehyde resin (low molecular weight)

p-tert-Butylphenol-formaldehyde resin is a widely used adhesive chemical used in a wide variety of commercially available products and a known dermatological sensitizer and allergen [A34290,A34291]. Sensitivity to p-tert-Butylphenol-formaldehyde resin may be identified with a clinical patch test.
Approved
Experimental
Matched Name: … p-tert-Butylphenol-formaldehyde resin (low molecular weight) …
Matched Description: … Sensitivity to p-tert-Butylphenol-formaldehyde resin may be identified with a clinical patch test. ... p-tert-Butylphenol-formaldehyde resin is a widely used adhesive chemical used in a wide variety of commercially …

Benzocaine

Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Synonyms: … p-Carbethoxyaniline ... Ethyl p-aminobenzoate ... p-(Ethoxycarbonyl)aniline …
Matched Mixtures name: … NORAVER P TABLETAS DE DISOLUCIÓN BUCAL ... NORAVER P TABLETAS DE DISOLUCIÓN BUCAL …
Matched Categories: … P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP2B6 Substrates ... Cytochrome P-450 CYP2D6 Substrates …

Hydroquinone

Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Synonyms: … p-Benzenediol ... p-Hydroquinone ... p-hydroxyphenol …

Ethyl hydroxybenzoate

Approved
Experimental
Matched Synonyms: … Ethyl p-hydroxybenzoate ... p-Oxybenzoesaeureaethylester ... p-hydroxybenzoic acid ethyl ester …

Aminoglutethimide

An aromatase inhibitor that produces a state of "medical" adrenalectomy by blocking the production of adrenal steroids. It also blocks the conversion of androgens to estrogens. Aminoglutethimide has been used in the treatment of advanced breast and prostate cancer. It was formerly used for its weak anticonvulsant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … p-Aminoglutethimide ... 2-(p-Aminophenyl)-2-ethylglutarimide ... α-(p-Aminophenyl)-α-ethylglutarimide …
Matched Categories: … Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP2C19 Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2C19 Inducers (strength unknown) …

Bromodiphenhydramine

Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.
Approved
Matched Synonyms: … β-(p-bromobenzhydryloxy)ethyldimethylamine ... β-dimethylaminoethyl p-bromobenzhydryl ether ... 2-(p-bromo-α-phenylbenzyloxy)-N,N-dimethylethylamine …

Astemizole

Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Approved
Withdrawn
Matched Synonyms: … 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole ... 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole …
Matched Categories: … P-glycoprotein inhibitors ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2D6 Substrates ... Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A Substrates …

Aminobenzoic acid

A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Synonyms: … p-Carboxyaniline ... p-Aminobenzoic acid ... p-Carboxyphenylamine …

Zinc phenolsulfonate

Approved
Experimental
Matched Synonyms: … Zinc p-phenolsulfonate ... Zinc p-phenolsulphonate ... p-hydroxybenzenesulfonic acid zinc salt …

Celecoxib

Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Synonyms: … p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide …
Matched Categories: … P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2C9 Substrates …

Aminohippuric acid

The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … p-aminohippurate ... p-aminohippuric acid ... N-(p-Aminobenzoyl)glycine …

Sulfacetamide

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Synonyms: … p-Aminobenzenesulfonacetamide ... N-((p-Aminophenyl)sulfonyl)acetamide ... N-(p-Aminobenzenesulfonyl)acetamide …

Benzylparaben

Benzylparaben is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … Benzyl p-hydroxybenzoate ... p-Hydroxybenzoic acid benzyl ester …

Clofibrate

A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Approved
Investigational
Matched Synonyms: … Ethyl 2-(p-chlorophenoxy)isobutyrate ... alpha-p-Chlorophenoxyisobutyryl ethyl ester ... alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP2E1 Inducers ... Cytochrome P-450 CYP2A6 Inhibitors ... Cytochrome P-450 CYP3A4 Inducers …

N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine

N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine is a component of black rubber. It is also a dermatological sensitizer and allergen. Sensitivity to N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine may be identified with a clinical patch test.
Approved
Matched Synonyms: … N-Cyclohexyl-N'-phenyl-p-phenylendiamine ... N-cyclohexyl-N'-phenyl-p-phenylenediamine …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Diethylaminoethyl p-aminobenzoate ... β-(diethylamino)ethyl p-aminobenzoate ... p-Aminobenzoic acid 2-diethylaminoethyl ester …

Dienestrol

Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of...
Approved
Investigational
Matched Synonyms: … p,p'-(Diethylideneethylene)diphenol …

Baclofen

Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … DL-4-Amino-3-p-chlorophenylbutanoic acid ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid ... beta-(p-Chlorophenyl)-gamma-aminobutyric acid …

Sulfanilamide

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Approved
Matched Synonyms: … p-aminobenzenesulfamide ... p-aminobenzenesulfonamide …
Matched Categories: … Cytochrome P-450 CYP3A Inhibitors ... Cytochrome P-450 CYP3A4 Inhibitors ... Cytochrome P-450 CYP2C19 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors …

Proguanil

Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite.
Approved
Matched Synonyms: … 1-(p-Chlorophenyl)-5-isopropylbiguanide …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP2C19 Substrates ... Cytochrome P-450 CYP2D6 Inhibitors ... Cytochrome P-450 Enzyme Inhibitors …

Monobenzone

Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. It exerts a depigmenting effect on skin of mammals by increasing the excretion of melanin from the melanocytes. It may also cause...
Approved
Matched Synonyms: … p-(Benzyloxy)phenol ... Benzyl p-hydroxyphenyl ether ... p-Hydroxyphenyl benzyl ether …

Pentamidine

Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Approved
Investigational
Matched Synonyms: … p,p'-(pentamethylenedioxy)dibenzamidine …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2D6 Substrates ... Cytochrome P-450 CYP3A5 Substrates ... Cytochrome P-450 CYP2C19 Substrates …

4-(Isopropylamino)diphenylamine

4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen. Sensitivity to this compound may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … N-Fenyl-N'-isopropyl-p-fenylendiamin ... N-Isopropyl-N'-phenyl-p-phenylenediamine ... p-Phenylenediamine, N-isopropyl-N'-phenyl …

Anisindione

Anisindione is a synthetic anticoagulant and an indanedione derivative. Its anticoagulant action is mediated through the inhibition of the vitamin K-mediated gamma-carboxylation of precursor proteins that are critical in forming the formation of active procoagulation factors II, VII, IX, and X, as well as the anticoagulant proteins C and S,...
Approved
Matched Synonyms: … 2-p-Anisyl-1,3-indandione ... 2-(p-Methoxyphenyl)-1,3-indandione ... 2-(p-Methoxyphenyl)indane-1,3-dione …
Displaying drugs 1 - 25 of 7231 in total