Displaying drugs 3751 - 3775 of 11286 in total
Tafluprost
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Description: … Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. ... A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma …
Hesperidin
Hesperidin is a flavan-on glycoside found in citrus fruits.
Approved
Investigational
Matched Description: … Hesperidin is a flavan-on glycoside found in citrus fruits. …
Diethylstilbestrol
A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed)
The FDA withdrew its...
Approved
Investigational
Withdrawn
Matched Description: … It was also used formerly as a growth promoter in animals. ... A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. ... to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a …
Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen
Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine for intramuscular injection indicated for the active immunization to prevent invasive disease caused by Neisseria meningitidis serogroup B. It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated...
Approved
Matched Description: … Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine ... factor H binding protein (fHBP) variants from N. meningitidis serogroup B, one from fHBP subfamily A ... It is contained in the suspension of Trumenba, which is a vaccine is composed of two recombinant lipidated …
Rifampicin
A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts...
Approved
Matched Description: … A semisynthetic antibiotic produced from Streptomyces mediterranei. ... It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. ... In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex …
Hyaluronidase (human recombinant)
A purified preparation of the enzyme recombinant human hyaluronidase. Hyaluronidase (human recombinant) (INN Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). Hyaluronidase is an enzyme used to improve the absorption and dispersion of...
Approved
Investigational
Matched Description: … A purified preparation of the enzyme recombinant human hyaluronidase. ... DNA plasmid encoding for a soluble fragment of human hyaluronidase (PH20). ... Vorhyaluronidase alfa) is produced by genetically engineered Chinese Hamster Ovary (CHO) cells containing a …
Unoprostone
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate.
The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Description: … Unoprostone isopropyl is a prostaglandin analogue. ... Ophthalmic Solution 0.15% is a synthetic docosanoid. …
DL-dimyristoylphosphatidylglycerol
DL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations to solubilize drugs for injection.
Approved
Matched Description: … DL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations …
Metergoline
Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors. Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration and agonist at dopamine receptors. Its use has been studied in various clinical settings such as a treatment for seasonal...
Approved
Matched Description: … Metergoline is an antagonist at various 5-HT receptor subtypes at a relatively low concentration and ... Metergoline is an ergot-derived psychoactive drug that acts as a ligand for serotonin and dopamine receptors ... [A27181] Its use has been studied in various clinical settings such as a treatment for seasonal affective …
Ragweed pollen extract
Ragweed pollen extract has been developed by Curalogic. The company has initiated a phase III trial with its product for oral immunotherapy of ragweed allergy. While traditional disease-modifying immunotherapeutics are administered by subcutaneous injection, Curalogic has developed a more convenient orally administered drug.
Approved
Investigational
Matched Description: … The company has initiated a phase III trial with its product for oral immunotherapy of ragweed allergy ... disease-modifying immunotherapeutics are administered by subcutaneous injection, Curalogic has developed a …
Vanillyl butyl ether
Vanillyl butyl ether is an ether of monohydroxybenzoic acid. It is added to food products as a flavoring agent. It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent, hair conditioning agent, and warming or cooling agent.
Approved
Matched Description: … It is added to food products as a flavoring agent. ... It is also present in cosmetics and personal care products as a fragrance ingredient, oral care agent …
Benziodarone
Benziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz. It is used in the treatment of gout . It was withdrawn from France markets and British markets due to its effects causing Jaundice in patients [T487, A175636].
Approved
Withdrawn
Matched Description: … Benziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz …
Valrubicin
Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the doxorubicin, which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Approved
Matched Description: … It is a semisynthetic analog of the [doxorubicin], which is an anthracycline drug. ... Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the …
Polydatin
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis …
Phenoxybenzamine
An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
Approved
Matched Description: … It has been used to treat hypertension and as a peripheral vasodilator. …
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Description: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a …
Safflower oil
Safflower (Carthamus tinctorius L) is a herbaceous plant in the Asteraceae family. Extracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids, monounsaturated fatty acid (oleic acid) or essential n-6 polyunsaturated fatty acid (PUFA) linoleic acid [A32677, A32679], depending on the flower type....
Approved
Investigational
Matched Description: … Safflower (_Carthamus tinctorius_ L) is a herbaceous plant in the Asteraceae family. ... Extracted from the seeds of safflowers, safflower oil is a rich source of various saturated fatty acids ... Safflower oil with a higher content of polyunsaturated fatty acids is more commonly used as an edible …
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Description: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a …
Thiothixene
A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
Approved
Matched Description: … A thioxanthine used as an antipsychotic agent. …
Polysilicone-15
Polysilicone-15 is a silicone based UVB absorber [L2796, L2797, L2799, F87, F88, F89]. The compound is a colorless to pale yellow viscous liquid which is soluble in organic solvents of medium polarity and insoluble in water [L2796, L2797, L2799, F87, F88, F89]. It is the first polymeric UVB filer consisting...
Approved
Matched Description: … Polysilicone-15 is a silicone based UVB absorber [L2796, L2797, L2799, F87, F88, F89]. ... The compound is a colorless to pale yellow viscous liquid which is soluble in organic solvents of medium ... It is the first polymeric UVB filer consisting of chromophores attached to a silicone backbone [L2796 …
Efavirenz
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Description: … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI ... ) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency ... postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a …
Keyhole limpet hemocyanin
Keyhole limpet hemocyanin is an immune modulator, given as a vaccine to help the body respond to cancer. A natural protein isolated from the marine mollusc keyhole limpet. Keyhole limpet hemocyanin is an immunogenic carrier protein that, in vivo, increases antigenic immune responses to haptens and other weak antigens such...
Approved
Investigational
Matched Description: … A natural protein isolated from the marine mollusc keyhole limpet. ... Keyhole limpet hemocyanin is an immune modulator, given as a vaccine to help the body respond to cancer …
Trifluoperazine
A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Approved
Investigational
Matched Description: … A phenothiazine with actions similar to chlorpromazine. …
Telavancin
Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant Staphylococcus aureus (MRSA) and other gram-positive bacteria. MRSA is an important pathogen capable of causing hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and skin and subcutaneous tissue infections among others.
Approved
Matched Description: … Telavancin is a semi-synthetic derivative of vanocymycin that has bactericidal activity against Methicillin-resistant …
Displaying drugs 3751 - 3775 of 11286 in total